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  1. Article ; Online: Deviating From the True Diagnosis.

    Chen, Zhiyong / Saini, Monica

    Journal of clinical neuromuscular disease

    2022  Volume 23, Issue 3, Page(s) 162

    Language English
    Publishing date 2022-02-21
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1454947-5
    ISSN 1537-1611 ; 1522-0443
    ISSN (online) 1537-1611
    ISSN 1522-0443
    DOI 10.1097/CND.0000000000000292
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    Zs.A 5293: Show issues Location:
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  2. Article: Demystifying pollution haven hypothesis: Role of FDI.

    Singhania, Monica / Saini, Neha

    Journal of business research

    2020  Volume 123, Page(s) 516–528

    Abstract: This study explores the interrelationship between FDI, institutional factors, financial development and sustainability by revisiting the pollution haven (or halo) hypotheses. The data is sourced from the World Development Indicators (WDI) database over ... ...

    Abstract This study explores the interrelationship between FDI, institutional factors, financial development and sustainability by revisiting the pollution haven (or halo) hypotheses. The data is sourced from the World Development Indicators (WDI) database over the period of 1990-2016, covering 21 developed and developing countries with high carbon emissions. The study uses dynamic panel data estimations by applying the generalized method of moments (GMM) and system-generalized methods of moments (Sys-GMM) over sample countries. The results indicate that FDI has a significant positive impact on environmental degradation. There is evidence of pollution haven hypotheses, especially in developing countries. We contribute to existing literature by revisiting the Environment Kuznets Curve (EKC) hypothesis and presenting the effect of FDI on carbon intensity in the light of institutional factors and financial development. The findings relating to FDI, institutional factors and financial development may cause researchers and policymakers to reiterate the sustainability dimension of foreign capital inflows in both developed and developing countries. We propose the policy framework to include a mandatory Statement of Environmental Disclosures for both listed and unlisted home and host companies at the time of their origin, expansion and fund raising in order to achieve sustainable business goals (SBGs).
    Keywords covid19
    Language English
    Publishing date 2020-10-20
    Publishing country United States
    Document type Journal Article
    ISSN 0148-2963
    ISSN 0148-2963
    DOI 10.1016/j.jbusres.2020.10.007
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  3. Article ; Online: Early detection of glaucoma integrated with deep learning models over medical devices.

    Saini, DilipKumar Jang Bahadur / Choubey, Siddhartha / Choubey, Abha / Kidwai, Mariyam / Mehrotra, Monica / Kolekar, Sagar / Raut, Yudhishthir

    Bio Systems

    2024  Volume 238, Page(s) 105156

    Abstract: The early detection of some diseases can be a decisive factor in postponing or stabilizing their most adverse effects on the people who suffer from them. In the case of glaucoma, which is an ocular pathology that is the second leading cause of blindness ... ...

    Abstract The early detection of some diseases can be a decisive factor in postponing or stabilizing their most adverse effects on the people who suffer from them. In the case of glaucoma, which is an ocular pathology that is the second leading cause of blindness in the world, early detection can make the difference between a patient's complete losses of vision, or preserve their sight, as well as improve their subsequent treatment. It is for this reason that there are currently medical campaigns for the early detection of pathologies with these characteristics in a certain study population, called screening, which have shown very good results. In addition, the application of telemedicine to these processes has allowed remote evaluation of cases by clinical experts and numerous initiatives have emerged for its use in new screening strategies. On the other hand, biomedical image processing techniques based on deep learning have undergone great development in recent years, and there are several works that have demonstrated their possible application in the automatic detection of glaucoma with fundus images. The article has consisted of the development of a web platform that integrates both scenarios: on the one hand, the remote evaluation of fundus images by medical specialists, and on the other, the application of a tool based on Deep Learning for the automatic detection of glaucoma in the case studies.
    MeSH term(s) Humans ; Deep Learning ; Glaucoma/diagnosis ; Fundus Oculi ; Image Processing, Computer-Assisted
    Language English
    Publishing date 2024-02-28
    Publishing country Ireland
    Document type Journal Article
    ZDB-ID 186234-0
    ISSN 1872-8324 ; 0303-2647
    ISSN (online) 1872-8324
    ISSN 0303-2647
    DOI 10.1016/j.biosystems.2024.105156
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  4. Article: Disentangling the Coronavirus Disease 2019 Health Disparities in African Americans: Biological, Environmental, and Social Factors.

    Saini, Geetanjali / Swahn, Monica H / Aneja, Ritu

    Open forum infectious diseases

    2021  Volume 8, Issue 3, Page(s) ofab064

    Abstract: The stark racial disparities related to the coronavirus disease 2019 (COVID-19) pandemic in the United States, wherein minority populations are disproportionately getting infected and succumbing to the disease, is of grave concern. It is critical to ... ...

    Abstract The stark racial disparities related to the coronavirus disease 2019 (COVID-19) pandemic in the United States, wherein minority populations are disproportionately getting infected and succumbing to the disease, is of grave concern. It is critical to understand and address the underlying causes of these disparities that are complex and driven by interacting environmental, social and biological factors. In this article we focus on the African American community and examine how social and environmental determinants of health intersect with biological factors (comorbidities, underlying genetics, host immunity, vitamin D levels, epigenetics) to exacerbate risk for morbidity and mortality.
    Language English
    Publishing date 2021-02-04
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2757767-3
    ISSN 2328-8957
    ISSN 2328-8957
    DOI 10.1093/ofid/ofab064
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  5. Article ; Online: Diversity analysis of endophytes with antimicrobial and antioxidant potential from Viola odorata: an endemic plant species of the Himalayas.

    Salwan, Richa / Rana, Aditi / Saini, Raj / Sharma, Amit / Sharma, Monica / Sharma, Vivek

    Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology

    2023  Volume 54, Issue 3, Page(s) 2361–2374

    Abstract: Viola odorata, also known as "Banafshah" in high altitudes of Himalayas, is well known for its pharmaceutical importance in Ayurvedic and Unani medicinal system. The plant is a source of various drugs for its anti-inflammatory, diaphoretic, diuretic, ... ...

    Abstract Viola odorata, also known as "Banafshah" in high altitudes of Himalayas, is well known for its pharmaceutical importance in Ayurvedic and Unani medicinal system. The plant is a source of various drugs for its anti-inflammatory, diaphoretic, diuretic, emollient, expectorant, antipyretic, and laxative properties. The endophytes of plants have been reported for their role in modulating various physiological and biological processes of the host plants. In the present study, a total of 244 endophytes were isolated in pure cultures from the roots of Viola odorata, and genetic diversity was evaluated using amplified ribosomal DNA restriction analysis (ARDRA) and enterobacterial repetitive intergenic consensus (ERIC). The molecular fingerprinting revealed variation among various rRNA types among morphologically different endophytes based on ARDRA and ERIC-PCR. The screening of endophytes showed antimicrobial activity of 11 bacterial isolates and one actinomycete SGA9 against various pathogens Bacillus cereus, Escherichia coli, Listeria monocytogenes, Pseudomonas aeruginosa, Staphylococcus aureus, and Staphylococcus epidermidis. The antioxidant activity revealed the majority of the bacterial isolates able to scavenge the free radical in the range of 10-50% and 8 bacterial isolates in the range of 50-85%. Principal component analysis separated eight isolates away from the central eclipse and form a separate group based on antimicrobial and antioxidant potential. The identification of these eight isolates showed affiliation with different species of the genus Enterobacter, Microbacterium, Pseudomonas, Rhizobium, and Streptomyces. This is the first report on the characterization of endophytic bacteria and actinomycetes from endemic Viola odorata. Results suggested that these endophytes could be explored for the production of antimicrobial and antioxidant products.
    MeSH term(s) Antioxidants/pharmacology ; Endophytes ; Viola/genetics ; Anti-Infective Agents/pharmacology ; Bacteria ; RNA, Ribosomal, 16S
    Chemical Substances Antioxidants ; Anti-Infective Agents ; RNA, Ribosomal, 16S
    Language English
    Publishing date 2023-05-25
    Publishing country Brazil
    Document type Journal Article
    ZDB-ID 2017175-4
    ISSN 1678-4405 ; 1517-8382
    ISSN (online) 1678-4405
    ISSN 1517-8382
    DOI 10.1007/s42770-023-01010-5
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  6. Article: Salmonella paratyphi

    Saini, Ruchika / Jesrani, Gautam / Gupta, Monica / Gupta, Samiksha / Chhabra, Ankit

    Turkish journal of emergency medicine

    2021  Volume 21, Issue 4, Page(s) 210–213

    Abstract: Splenic vein thrombosis and splenic infarction are complications beyond the usual clinical spectrum of paratyphoid fever, and the presentation is rarely described. We report the case of a young female, who presented with high-grade fever and severe left ... ...

    Abstract Splenic vein thrombosis and splenic infarction are complications beyond the usual clinical spectrum of paratyphoid fever, and the presentation is rarely described. We report the case of a young female, who presented with high-grade fever and severe left upper quadrant pain. Her blood culture was positive for
    Language English
    Publishing date 2021-10-29
    Publishing country India
    Document type Case Reports
    ISSN 2452-2473
    ISSN 2452-2473
    DOI 10.4103/2452-2473.329625
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  7. Article ; Online: Facial Nerve Involvement Accompanying Optic Neuritis Secondary to Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disorder.

    Chen, Zhiyong / Saini, Monica / Loo, Jing Liang

    Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society

    2020  Volume 41, Issue 3, Page(s) e378–e380

    Abstract: Abstract: We present the first reported case of facial nerve involvement accompanying an optic neuritis in myelin oligodendrocyte glycoprotein antibody-associated disorder. ...

    Abstract Abstract: We present the first reported case of facial nerve involvement accompanying an optic neuritis in myelin oligodendrocyte glycoprotein antibody-associated disorder.
    MeSH term(s) Autoantibodies/immunology ; Facial Nerve/diagnostic imaging ; Facial Nerve Diseases/complications ; Facial Nerve Diseases/diagnosis ; Facial Nerve Diseases/immunology ; Humans ; Magnetic Resonance Imaging/methods ; Male ; Myelin-Oligodendrocyte Glycoprotein/immunology ; Optic Neuritis/diagnosis ; Optic Neuritis/immunology ; Visual Acuity ; Young Adult
    Chemical Substances Autoantibodies ; Myelin-Oligodendrocyte Glycoprotein
    Language English
    Publishing date 2020-10-29
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 1189901-3
    ISSN 1536-5166 ; 1070-8022
    ISSN (online) 1536-5166
    ISSN 1070-8022
    DOI 10.1097/WNO.0000000000001145
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    Zs.A 1670: Show issues Location:
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  8. Article: Cefepime-Induced Neurotoxicity.

    Saini, Tanjot / Gaines, Monica N / Sohal, Aalam / Li, Lin

    Cureus

    2021  Volume 13, Issue 9, Page(s) e17831

    Abstract: Cefepime is a common antibiotic used to treat various infections such as pneumonia, skin infections, and intra-abdominal infections due to its broad gram-positive and gram-negative spectrum. However, patients with acute kidney injury, end-stage renal ... ...

    Abstract Cefepime is a common antibiotic used to treat various infections such as pneumonia, skin infections, and intra-abdominal infections due to its broad gram-positive and gram-negative spectrum. However, patients with acute kidney injury, end-stage renal disease, and renal transplantation are disproportionately at higher risk of developing complications from administration of cefepime, secondary to its predominant renal excretion. Current guidelines prescribe cefepime renal-dosing, dependent on the glomerular filtration rate, to prevent toxicity. This study presents a rare case where an acutely hospitalized patient undergoing chronic renal transplant rejection was administered renal-dose cefepime. Despite renal dosing, the patient developed neurotoxicity that manifested as delirium, inability to tolerate oral intake, and non-convulsive status epilepticus. Solely adjusting for renal dysfunction may be inadequate to prevent the accumulation of cefepime metabolites, which may present in an atypical manner in the patient. Such possibilities emphasize the need for continued evaluation of a patient's mentation in case of cefepime administration. Cefepime-induced neurotoxicity incidences need to be evaluated and researched thoroughly.
    Language English
    Publishing date 2021-09-08
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.17831
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  9. Article: Diabetes Ketoacidosis Complicating as Wrist Drop: A Case Report on Acute Motor Neuropathy.

    Arora, Shreya / Gupta, Shivani / Jesrani, Gautam / Saini, Ruchika / Gupta, Monica

    Cureus

    2021  Volume 13, Issue 8, Page(s) e17081

    Abstract: Diabetic ketoacidosis (DKA) is an acute and major complication of diabetes mellitus. Neurological complications can be seen at any time during the course of illness and range from decreased consciousness to ischemic or hemorrhagic stroke. Acute ... ...

    Abstract Diabetic ketoacidosis (DKA) is an acute and major complication of diabetes mellitus. Neurological complications can be seen at any time during the course of illness and range from decreased consciousness to ischemic or hemorrhagic stroke. Acute neuropathy is very rare in this milieu. Here, we report a case of a 40-year-old patient, who developed a left-sided wrist drop after being treated for DKA. The nerve conduction velocity studies demonstrated decreased action potential amplitude in only the motor component of the left radial nerve. Other possible causes of the complaint were ruled out and the patient was managed with cock-up splint, vitamin B1 and B6 supplementation, and physiotherapy. Despite all these measures, the patient had minimal improvement. Thus, close monitoring of patients is crucial to identify these infirmities, even after the acute condition has resolved.
    Language English
    Publishing date 2021-08-11
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.17081
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  10. Article ; Online: Atypical mucormycosis masquerading as non-resolving cavitatory pneumonia: A frequently misdiagnosed entity.

    Saini, Ruchika / Syal, Arshi / Gaba, Saurabh / Gupta, Monica / Arya, Yajur

    Tropical doctor

    2021  Volume 51, Issue 2, Page(s) 282–284

    Abstract: We are reporting an unusual case of cavitatory pulmonary mucormycosis in a patient with uncontrolled type 2 diabetes mellitus who was treated successfully. This is a unique case of pulmonary mucormycosis masquerading as cavitatory pulmonary disease. A 45- ...

    Abstract We are reporting an unusual case of cavitatory pulmonary mucormycosis in a patient with uncontrolled type 2 diabetes mellitus who was treated successfully. This is a unique case of pulmonary mucormycosis masquerading as cavitatory pulmonary disease. A 45-year-old female presented with fever, chest pain, cough and breathlessness. She was also found to have very high blood glucose due to previously undiagnosed diabetes. Diabetic ketoacidosis is the most common predisposing factor for mucormycosis. Our patient had uncontrolled diabetes and presented with bilateral cavitatory pulmonary lesions even in the absence of diabetic ketoacidosis. Appropriate investigations were ordered, and alternate causes of lung cavitation were diligently excluded. She was treated with amphotericin-B for three weeks followed by oral posaconazole for eight weeks with excellent outcome. A low threshold for detection as well as a differential of mucormycosis must be kept in immunocompromised patients presenting with cavitatory lung disease.
    Language English
    Publishing date 2021-02-14
    Publishing country England
    Document type Journal Article
    ZDB-ID 193169-6
    ISSN 1758-1133 ; 0049-4755
    ISSN (online) 1758-1133
    ISSN 0049-4755
    DOI 10.1177/0049475521991340
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