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  1. Book ; Conference proceedings: Albert Heim

    Heim, Albert

    (1849 - 1937) ; Professor für Geologie an ETH und Universität Zürich ; Katalog zur Gedenkausstellung 1987

    (Schriftenreihe der ETH-Bibliothek ; 23)

    1988  

    Event/congress Gedenkausstellung. (Zürich) (1987)
    Series title Schriftenreihe der ETH-Bibliothek ; 23
    Language German
    Size V, 63 S., überwiegend Ill., graph. Darst, 21 x 30 cm
    Publisher ETH-Bibliothek
    Publishing place Zürich
    Document type Book ; Conference proceedings
    Database Former special subject collection: coastal and deep sea fishing

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  2. Book ; Article ; Online: Albert Heim (1849-1937)

    Heim, Albert

    Schriftenreihe der ETH-Bibliothek, 23

    Katalog zur Gedenkausstellung 1987

    1988  

    Keywords PUBLIKATIONEN ZU TEMPORÄREN AUSSTELLUNGEN ; GEOLOGIE + REGIONAL GEOLOGIE + ERDWISSENSCHAFTEN ; Heim ; Albert ; SCHWEIZ (MITTELEUROPA). SCHWEIZERISCHE EIDGENOSSENSCHAFT ; PUBLICATIONS ON TEMPORARY EXHIBITIONS ; GEOLOGY + REGIONAL GEOLOGY + EARTH SCIENCES ; SWITZERLAND (CENTRAL EUROPE). SWISS CONFEDERATION ; info:eu-repo/classification/ddc/550 ; Earth sciences
    Language German
    Publisher ETH-Bibliothek
    Publishing country ch
    Document type Book ; Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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  3. Book ; Online: Albert Heim (1849-1937 - Prof.für Geologie ETH u. Univ.Zürich)

    Heim, Albert

    Handschriften und Autographen der ETH-Bibliothek, 47

    (Bibliographie Manuskripte - Korrespondenz)

    1985  

    Keywords HANDSCHRIFTENVERZEICHNISSE + HANDSCHRIFTENKATALOGE ; Heim ; Albert ; BRIEFE + BRIEFWECHSEL (DOKUMENTENTYP) ; KATALOGE/ALLGEMEIN (AUSSER BÜCHERKATALOGE) ; MANUSCRIPT LITERATURE BIBLIOGRAPHIES ; LETTERS + CORRESPONDENCE (DOCUMENT TYPES) ; CATALOGUES/GENERAL (NO BOOK LISTS) ; info:eu-repo/classification/ddc/550 ; Earth sciences
    Language German
    Publisher Wissenschaftshistorische Sammlung der ETH-Bibliothek
    Publishing country ch
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article: Evaluation of the Procleix Ultrio Elite Assay and the Panther-System for Individual NAT Screening of Blood, Hematopoietic Stem Cell, Tissue and Organ Donors.

    Heim, Albert

    Transfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie

    2016  Volume 43, Issue 3, Page(s) 177–182

    Abstract: Background: The performance of the multiplex Procleix Ultrio Elite assay as individual donor nucleic acid test (ID-NAT) for the detection of HIV-1, HIV-2, HCV, and HBV was evaluated in a retrospective, single center study.: Methods: ID-NAT results of ...

    Abstract Background: The performance of the multiplex Procleix Ultrio Elite assay as individual donor nucleic acid test (ID-NAT) for the detection of HIV-1, HIV-2, HCV, and HBV was evaluated in a retrospective, single center study.
    Methods: ID-NAT results of 21,181 blood donors, 984 tissue donors, 293 hematopoietic stem cell donors and 4 organ donors were reviewed in synopsis with results of serological screening and additional discriminatory and repetitive NAT in case of positive donors.
    Results: Specificity of the initial Procleix Ultrio Elite assay was 99.98% and after discriminatory testing 100.00%. Initially invalid results were observed in 75 of 21,181 blood donors (0.35%) but 16 of 984 tissue donors (1.62%, p < 0.001) which included non-heart-beating ('cadaveric') donors. All these had valid negative ID-NAT results after repeated testing or testing of 1:5 diluted specimens in case of tissue donors. Occult hepatitis B (defined here as HBV DNAemia without HBsAg detection) was demonstrated by ID-NAT in two anti-HBc-positive tissue donors and suspected in two other tissue donors, where a definite diagnosis was not achieved due to the insufficient sample volumes available.
    Conclusion: The Procleix Ultrio Elite assay proved to be specific, robust and rapid. Therefore, routine ID-NAT may also be feasible for organ and granulocyte donors.
    Language English
    Publishing date 2016-05-03
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2100848-6
    ISSN 1660-3818 ; 1660-3796
    ISSN (online) 1660-3818
    ISSN 1660-3796
    DOI 10.1159/000446217
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Rapid random access detection of the novel SARS-coronavirus-2 (SARS-CoV-2, previously 2019-nCoV) using an open access protocol for the Panther Fusion.

    Cordes, Anne K / Heim, Albert

    Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology

    2020  Volume 125, Page(s) 104305

    MeSH term(s) Automation, Laboratory ; Betacoronavirus/genetics ; COVID-19 ; COVID-19 Testing ; COVID-19 Vaccines ; Clinical Laboratory Techniques/methods ; Coronavirus Envelope Proteins ; Coronavirus Infections/diagnosis ; Coronavirus RNA-Dependent RNA Polymerase ; Humans ; Pandemics ; Pneumonia, Viral/diagnosis ; RNA-Dependent RNA Polymerase/genetics ; Real-Time Polymerase Chain Reaction/methods ; Reverse Transcriptase Polymerase Chain Reaction/methods ; SARS-CoV-2 ; Viral Envelope Proteins/genetics ; Viral Nonstructural Proteins/genetics
    Chemical Substances COVID-19 Vaccines ; Coronavirus Envelope Proteins ; Covid-19 aAPC vaccine ; Viral Envelope Proteins ; Viral Nonstructural Proteins ; envelope protein, SARS-CoV-2 ; Coronavirus RNA-Dependent RNA Polymerase (EC 2.7.7.48) ; NSP12 protein, SARS-CoV-2 (EC 2.7.7.48) ; RNA-Dependent RNA Polymerase (EC 2.7.7.48)
    Keywords covid19
    Language English
    Publishing date 2020-02-28
    Publishing country Netherlands
    Document type Letter
    ZDB-ID 1446080-4
    ISSN 1873-5967 ; 1386-6532
    ISSN (online) 1873-5967
    ISSN 1386-6532
    DOI 10.1016/j.jcv.2020.104305
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 3790: Show issues Location:
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  6. Book: Dissoziation und Kultur

    Wolfradt, Uwe / Heim, Gerhard / Fiedler, Peter

    (Pierre Janets Beiträge zur modernen Psychiatrie und Psychologie ; 3)

    2013  

    Author's details Uwe Wolfradt ; Gerhard Heim ; Peter Fiedler (Hrsg.)
    Series title Pierre Janets Beiträge zur modernen Psychiatrie und Psychologie ; 3
    Collection
    Language German
    Size 118 S. : Ill., 210 mm x 148 mm
    Publisher Pabst Scienc Publ
    Publishing place Lengerich
    Publishing country Germany
    Document type Book
    HBZ-ID HT018226833
    ISBN 978-3-89967-887-1 ; 978-3-89967-668-6 ; 3-89967-887-7 ; 3-89967-668-8
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2014 A 1799 available for loan (reading room) Lesesaal EG

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  7. Article: Molecular phylogeny of human adenovirus type 41 lineages.

    Götting, Jasper / Cordes, Anne K / Steinbrück, Lars / Heim, Albert

    Virus evolution

    2022  Volume 8, Issue 2, Page(s) veac098

    Abstract: Type 41 of human adenovirus species F (HAdV-F41) is a frequent aetiology of gastroenteritis in children, and nosocomial as well as kindergarten outbreaks have been frequently described. In contrast to other HAdV types, HAdV-F41 was not associated with a ... ...

    Abstract Type 41 of human adenovirus species F (HAdV-F41) is a frequent aetiology of gastroenteritis in children, and nosocomial as well as kindergarten outbreaks have been frequently described. In contrast to other HAdV types, HAdV-F41 was not associated with a life-threatening disseminated disease in allogeneic haematopoietic stem cell transplant (HSCT) recipients or any severe organ infections so far. Due to the limited clinical significance, the evolution of HAdV-F41 has not been studied in detail. Recently, HAdV-F41 has been associated with severe hepatitis in young children, and interest in HAdV-F41 has skyrocketed, although the aetiology of hepatitis has not been resolved. Complete genomic HAdV-F41 sequences from thirty-two diagnostic specimens of the past 11 years (2011-22) were generated, all originating from gastroenteritis patients. Additionally, thirty-three complete HAdV-F41 genomes from GenBank were added to our phylogenetic analysis. Phylogenetic analysis of sixty-five genomes indicated that HAdV-F41 evolved with three lineages co-circulating. Lineage 1 included the prototype 'Tak' from 1973 and six isolates from 2007 to 2017 with an average nucleotide identity of 99.3 per cent. Lineage 2 included 53 isolates from 2000 to 2022, had an average nucleotide identity of 99.8 per cent, and split into two sublineages. Lineage 3, probably described for the first time in 2009, had a 45-nucleotide deletion in the long fibre gene and had evolved significantly in the short fibre and E3 region. Moreover, a recent Lineage 3 isolate from 2022 had a recombinant phylogeny of the short fibre gene. Fibres interact with cellular receptors and determine cellular tropism, whereas E3 gene products interfere with the immune recognition of HAdV-infected cells. This in-depth study on the phylogeny of HAdV-F41 discovered significant evolution of recently described Lineage 3 of HAdV-F41, possibly resulting in altered cellular tropism, virulence, and pathophysiology.
    Language English
    Publishing date 2022-10-20
    Publishing country England
    Document type Journal Article
    ZDB-ID 2818949-8
    ISSN 2057-1577
    ISSN 2057-1577
    DOI 10.1093/ve/veac098
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Book: Schlüsselthemen der Psychotherapie

    Wolfradt, Uwe / Fiedler, Peter / Heim, Gerhard

    (Pierre Janets Beiträge zur modernen Psychiatrie und Psychologie ; Band 4)

    2017  

    Author's details Uwe Wolfradt, Peter Fiedler, Gerhard Heim (Hrsg.)
    Series title Pierre Janets Beiträge zur modernen Psychiatrie und Psychologie ; Band 4
    Collection
    Keywords Janet, Pierre ; Psychotherapie
    Subject Behandlung ; Psychologische Behandlung
    Language German ; English
    Size 127 Seiten, Illustrationen
    Publisher Pabst Science Publishers
    Publishing place Lengerich
    Publishing country Germany
    Document type Book
    Note Beiträge überwiegend deutsch, 1 Beitrag englisch
    HBZ-ID HT019469814
    ISBN 978-3-95853-340-0 ; 3-95853-340-X ; 9783958533417 ; 3958533418
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2018 A 182 available for loan (reading room) Lesesaal EG

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  9. Book ; Thesis: Synergistische Interaktion zwischen Interferon-beta und Interferon-gamma in persistent Coxsackievirus B3 infizierten "Carrier-State"-Kulturen humaner myokardialer Bindegewebszellen

    Heim, Albert Roland

    1992  

    Author's details vorgelegt von Albert Roland Heim
    Size 123 S. : Ill., graph. Darst.
    Document type Book ; Thesis
    Thesis / German Habilitation thesis München, Univ., Diss., 1992
    HBZ-ID HT004447993
    Database Catalogue ZB MED Medicine, Health

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    Shelf markLoan statusLocation
    93 D 869 order for loan Magazin

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  10. Article: Evaluation of the Procleix Ultrio Elite Assay and the Panther-System for Individual NAT Screening of Blood, Hematopoietic Stem Cell, Tissue and Organ Donors

    Heim, Albert

    Transfusion Medicine and Hemotherapy

    2016  Volume 43, Issue 3, Page(s) 177–182

    Abstract: Background: The performance of the multiplex Procleix Ultrio Elite assay as individual donor nucleic acid test (ID-NAT) for the detection of HIV-1, HIV-2, HCV, and HBV was evaluated in a retrospective, single center study. Methods: ID-NAT results of 21, ... ...

    Institution Institut für Virologie, Medizinische Hochschule Hannover, Hanover, Germany
    Abstract Background: The performance of the multiplex Procleix Ultrio Elite assay as individual donor nucleic acid test (ID-NAT) for the detection of HIV-1, HIV-2, HCV, and HBV was evaluated in a retrospective, single center study. Methods: ID-NAT results of 21,181 blood donors, 984 tissue donors, 293 hematopoietic stem cell donors and 4 organ donors were reviewed in synopsis with results of serological screening and additional discriminatory and repetitive NAT in case of positive donors. Results: Specificity of the initial Procleix Ultrio Elite assay was 99.98% and after discriminatory testing 100.00%. Initially invalid results were observed in 75 of 21,181 blood donors (0.35%) but 16 of 984 tissue donors (1.62%, p < 0.001) which included non-heart-beating (‘cadaveric') donors. All these had valid negative ID-NAT results after repeated testing or testing of 1:5 diluted specimens in case of tissue donors. Occult hepatitis B (defined here as HBV DNAemia without HBsAg detection) was demonstrated by ID-NAT in two anti-HBc-positive tissue donors and suspected in two other tissue donors, where a definite diagnosis was not achieved due to the insufficient sample volumes available. Conclusion: The Procleix Ultrio Elite assay proved to be specific, robust and rapid. Therefore, routine ID-NAT may also be feasible for organ and granulocyte donors.
    Keywords HBV ; HCV ; HIV ; Nucleic acid amplification ; Transfusion ; Transplantation ; Virus safety
    Language English
    Publishing date 2016-05-03
    Publisher S. Karger GmbH
    Publishing place Freiburg, Germany
    Document type Article
    Note Original Article
    ZDB-ID 2100848-6
    ISSN 1660-3818 ; 1660-3796
    ISSN (online) 1660-3818
    ISSN 1660-3796
    DOI 10.1159/000446217
    Database Karger publisher's database

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