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  1. Article ; Online: Advantages of Delayed Sequence Intubation in Selected Patients With COVID-19.

    Castro de Oliveira, Bruna Maria / de Souza, Renato Lucas Passos

    Anesthesia and analgesia

    2020  Volume 131, Issue 2, Page(s) e133–e134

    MeSH term(s) Betacoronavirus ; COVID-19 ; Coronavirus Infections/diagnosis ; Coronavirus Infections/physiopathology ; Coronavirus Infections/therapy ; Humans ; Hypnotics and Sedatives/administration & dosage ; Intubation, Intratracheal/methods ; Pandemics ; Pneumonia, Viral/diagnosis ; Pneumonia, Viral/physiopathology ; Pneumonia, Viral/therapy ; Pulmonary Ventilation/drug effects ; Pulmonary Ventilation/physiology ; SARS-CoV-2
    Chemical Substances Hypnotics and Sedatives
    Keywords covid19
    Language English
    Publishing date 2020-08-19
    Publishing country United States
    Document type Letter
    ZDB-ID 80032-6
    ISSN 1526-7598 ; 0003-2999
    ISSN (online) 1526-7598
    ISSN 0003-2999
    DOI 10.1213/ANE.0000000000004977
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  2. Article ; Online: Molecular characterization of Chikungunya virus recovered from patients in the Maranhão state, Brazil.

    Junior, Antônio Dantas Silva / de Melo, Bruna Oliveira / Costa, Antonia Khaynnam Silva / de Jesus Ferreira Costa, Daniela / Castro, Érima Jôyssielly Mendonça / de Jesus Gomes Turri, Rosimary / de Sousa Monteiro, Andrea / Zagmignan, Adrielle / Bomfim, Maria Rosa Quaresma / de Silva, Luís Cláudio Nascimento

    Molecular biology reports

    2024  Volume 51, Issue 1, Page(s) 375

    Abstract: ... Indian Ocean Lineage (IOL). The ECSA genotype was first registered in Brazil in Feira de Santana and spread ... of the genome. The isolates were highly similar (> 99%) to the ECSA isolate from Feira de Santana (BHI3734 ...

    Abstract Background: Chikungunya virus (CHIKV) is an arbovirus from the Togaviridae family which has four genotypes: West African (WA), East/Central/South African (ECSA) and Asian/Caribbean lineage (AL) and Indian Ocean Lineage (IOL). The ECSA genotype was first registered in Brazil in Feira de Santana and spread to all Brazilian regions. This study reports the characterization of CHIKV isolates recovered from sera samples of fifty patients from seventeen cities in Maranhão, a state from Brazilian northeast region and part of the Legal Amazon area.
    Methods and results: Primers were developed to amplify the partial regions coding structural proteins (E1, E3, E2, 6 K, and Capsid C). The consensus sequences have 2871 bp, covering approximately 24% of the genome. The isolates were highly similar (> 99%) to the ECSA isolate from Feira de Santana (BHI3734/H804698), presenting 30 non-synonymous mutations in E1 (5.95%), 18 in E2 (4.46%), and 1 in E3 (3.03%), taking the BHI3734/H804698 isolate as standard. Although the mutations described have not previously been related to increased infectivity or transmissibility of CHIKV, in silico analysis showed changes in physicochemical characteristics, antigenicity, and B cell epitopes of E1 and E2.
    Conclusions: These findings demonstrate the importance of molecular approaches for monitoring the viral adaptations undergone by CHIKV and its geographic distribution.
    MeSH term(s) Humans ; Chikungunya virus/genetics ; Chikungunya Fever/epidemiology ; Brazil ; Disease Outbreaks ; Phylogeny ; Genotype
    Language English
    Publishing date 2024-03-01
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 186544-4
    ISSN 1573-4978 ; 0301-4851
    ISSN (online) 1573-4978
    ISSN 0301-4851
    DOI 10.1007/s11033-024-09252-8
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  3. Article ; Online: Fatty acids analysis by capillary electrophoresis: Fundamentals, advantages and applications.

    Geraldo, Patrícia Abranches / Velasco, Arthur Woyames de Castro / Berlande, Bruna Marchiori / Souza, Jéssica Cordeiro Queiroz de / Candido, João Marcos Beraldo / Adriano, Luiz Henrique Cantarino / Brito, Marco Antônio Domingues Assad E / do Nascimento, Maria Patrícia / Moreira, Olívia Brito de Oliveira / de Oliveira, Marcone Augusto Leal

    Electrophoresis

    2023  Volume 45, Issue 1-2, Page(s) 35–54

    Abstract: This review covers the know-how of the Grupo de Química Analítica e Quimiometria regarding ...

    Abstract This review covers the know-how of the Grupo de Química Analítica e Quimiometria regarding the analysis of fatty acids by capillary electrophoresis acquired over its 20 years of existence. Therefore, the fundamentals, advantages, and applications of this technique for analyzing different fatty acids in samples such as food, oils, cosmetics, and biological matrices are presented and discussed. Capillary electrophoresis is, thus, shown as an interesting and valuable separation technique for the target analysis of these analytes as an alternative to the gas chromatography coupled to flame ionization detection, as it offers advantages over the latter such as low analysis times, low sample and reagent consumption, the use of a nondedicated column, and simpler sample preparation. In addition, the methods shown in this literature review can be useful for quality control, adulteration, and health-related research by regulatory agencies.
    MeSH term(s) Fatty Acids/analysis ; Electrophoresis, Capillary/methods ; Chromatography, Gas/methods ; Oils ; Drug Contamination
    Chemical Substances Fatty Acids ; Oils
    Language English
    Publishing date 2023-11-09
    Publishing country Germany
    Document type Journal Article ; Review
    ZDB-ID 619001-7
    ISSN 1522-2683 ; 0173-0835
    ISSN (online) 1522-2683
    ISSN 0173-0835
    DOI 10.1002/elps.202300144
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  6. Article ; Online: Advantages of Delayed Sequence Intubation in Selected Patients With COVID-19

    Castro de Oliveira, Bruna Maria / de Souza, Renato Lucas Passos

    Anesthesia & Analgesia

    2020  Volume 131, Issue 2, Page(s) e133–e134

    Keywords Anesthesiology and Pain Medicine ; covid19
    Language English
    Publisher Ovid Technologies (Wolters Kluwer Health)
    Publishing country us
    Document type Article ; Online
    ZDB-ID 80032-6
    ISSN 1526-7598 ; 0003-2999
    ISSN (online) 1526-7598
    ISSN 0003-2999
    DOI 10.1213/ane.0000000000004977
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article ; Online: Fatty acids analysis by capillary electrophoresis: Fundamentals, advantages and applications

    Geraldo, Patrícia Abranches / Velasco, Arthur Woyames de Castro / Berlande, Bruna Marchiori / Souza, Jéssica Cordeiro Queiroz de / Candido, João Marcos Beraldo / Adriano, Luiz Henrique Cantarino / Brito, Marco Antônio Domingues Assad e / do Nascimento, Maria Patrícia / Moreira, Olívia Brito de Oliveira / de Oliveira, Marcone Augusto Leal

    ELECTROPHORESIS. 2024 Jan., v. 45, no. 1-2 p.35-54

    2024  

    Abstract: This review covers the know‐how of the Grupo de Química Analítica e Quimiometria regarding ...

    Abstract This review covers the know‐how of the Grupo de Química Analítica e Quimiometria regarding the analysis of fatty acids by capillary electrophoresis acquired over its 20 years of existence. Therefore, the fundamentals, advantages, and applications of this technique for analyzing different fatty acids in samples such as food, oils, cosmetics, and biological matrices are presented and discussed. Capillary electrophoresis is, thus, shown as an interesting and valuable separation technique for the target analysis of these analytes as an alternative to the gas chromatography coupled to flame ionization detection, as it offers advantages over the latter such as low analysis times, low sample and reagent consumption, the use of a nondedicated column, and simpler sample preparation. In addition, the methods shown in this literature review can be useful for quality control, adulteration, and health‐related research by regulatory agencies.
    Keywords adulterated products ; capillary electrophoresis ; chemical species ; cosmetics ; flame ionization ; quality control
    Language English
    Dates of publication 2024-01
    Size p. 35-54.
    Publishing place John Wiley & Sons, Ltd
    Document type Article ; Online
    Note REVIEW
    ZDB-ID 619001-7
    ISSN 1522-2683 ; 0173-0835
    ISSN (online) 1522-2683
    ISSN 0173-0835
    DOI 10.1002/elps.202300144
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  8. Article ; Online: No Evidence of Rabies Exposure in Wild Marmosets (Callithrix jacchus) of Northeast Brazil.

    Benavides, Julio A / Megid, Jane / Castilho, Juliana Galera / Macedo, Carla I / Mourão Fuches, Regina Maria / Frazatti Gallina, Neuza Maria / Boere, Vanner / Zalafon-Silva, Bruna / da Silva, Ramiro Monã / Coutinho, José Flávio Vidal / Arruda, Maria de Fatima / de Oliveira E Silva, Ita / Valença-Montenegro, Mônica Mafra / Cordeiro, Jefferson Farias / Leal, Silvana / Higashi, Cintia de Sousa / Medeiros, Fabíola de Souza / Uchoa de Castro, Alene / Rizzo, Rodrigo /
    Sena, Fabio Antonio / Gonçalves, Paola de Cassia / Rocha, Silene Manrique / Wada, Marcelo / Vargas, Alexander / Carrieri, Maria Luiza / Kotait, Ivanete

    EcoHealth

    2024  Volume 20, Issue 4, Page(s) 355–361

    Abstract: Rabies transmitted by wildlife is the main source of human rabies mortality in Latin America and considered an emerging disease. The common marmoset Callithrix jacchus of Brazil is the only known primate reservoir of rabies worldwide. We tested whether ... ...

    Abstract Rabies transmitted by wildlife is the main source of human rabies mortality in Latin America and considered an emerging disease. The common marmoset Callithrix jacchus of Brazil is the only known primate reservoir of rabies worldwide. We tested whether alive free-ranging C. jacchus were exposed to rabies in four northeast states that have previously reported rabies-positive dead C. jacchus (Pernambuco and Bahia) or not (Paraíba and Rio Grande do Norte). Our results show no evidence of rabies antibodies or infection in the sampled C. jacchus, suggesting that apparently healthy marmosets are not widely exposed to rabies over their natural range.
    MeSH term(s) Animals ; Humans ; Rabies/veterinary ; Callithrix ; Rabies virus ; Brazil ; Animals, Wild
    Language English
    Publishing date 2024-01-18
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2164327-1
    ISSN 1612-9210 ; 1612-9202
    ISSN (online) 1612-9210
    ISSN 1612-9202
    DOI 10.1007/s10393-023-01663-6
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  9. Article: Temporal bone squamous cell carcinoma: Aggressive behavior coursing with cerebellar invasion and hydrocephalus.

    de Castro, Maria Eduarda Rosário Viveiros / Ferreira-Pinto, Pedro Henrique Costa / de Oliveira Ferreira, Domênica Baroni Coelho / Brito, Ana Carolina Gonçalves / Parise, Maud / Correa, Eduardo Mendes / Cruz, Thaina Zanon / de Freitas, Wesley Klein Nunes / de Gouvea, Pedro Luiz Ribeiro Carvalho / da Silva, Wellerson Novaes / de Sousa, Bruna Cavalcante / Videira, Hannah Ferreira Machado / Parra, Guilherme Freitas / Nigri, Flavio

    Surgical neurology international

    2024  Volume 15, Page(s) 89

    Abstract: Background: Temporal bone squamous cell carcinoma (TBSCC) is a very rare condition. The prognosis is dismal for advanced tumors. Due to its rarity, information in the literature is scarce. Here, we report a unique case of TBSCC with cerebellar invasion ... ...

    Abstract Background: Temporal bone squamous cell carcinoma (TBSCC) is a very rare condition. The prognosis is dismal for advanced tumors. Due to its rarity, information in the literature is scarce. Here, we report a unique case of TBSCC with cerebellar invasion and hydrocephalus.
    Case description: A 46-year-old reported right-sided hearing loss and a painful right retroauricular mass for 4 months. Magnetic resonance imaging revealed a 8.7 × 7.6 × 6.4 cm mass invading the right temporal and occipital bones. After a biopsy and 3 surgical procedures over 6 months, the diagnosis of TBSCC was obtained. Due to invasion of the cerebellar tissue and obstructive hydrocephalus, a ventriculoperitoneal shunt was performed. The patient was referred for adjuvant radiotherapy. However, palliative care was initiated due to tumor progression.
    Conclusion: We report a case of advanced TBSCC with poor prognosis despite surgical treatment and radiotherapy. More data are necessary to provide new and better treatment to these patients.
    Language English
    Publishing date 2024-03-15
    Publishing country United States
    Document type Case Reports
    ISSN 2229-5097
    ISSN 2229-5097
    DOI 10.25259/SNI_1017_2023
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  10. Article ; Online: Neutralizing antibody response after immunization with a COVID-19 bivalent vaccine: Insights to the future.

    Souza, Milena Silva / Farias, Jéssica Pires / Andreata-Santos, Robert / Silva, Marianne Pereira / Brito, Ruth Dálety da Silva / Duarte Barbosa da Silva, Marcia / Peter, Cristina Mendes / Cirilo, Marcus Vinícius de França / Luiz, Wilson Barros / Birbrair, Alexander / Vidal, Paloma Oliveira / de Castro-Amarante, Maria Fernanda / Candido, Erika Donizetti / Munhoz, Aldilene Silva / de Mello Malta, Fernanda / Dorlass, Erik Gustavo / Machado, Rafael Rahal Guaragna / Pinho, João Renato Rebello / Oliveira, Danielle Bruna Leal /
    Durigon, Edison Luiz / Maricato, Juliana Terzi / Braconi, Carla Torres / Ferreira, Luís Carlos de Souza / Janini, Luiz Mário Ramos / Amorim, Jaime Henrique

    Journal of medical virology

    2024  Volume 96, Issue 2, Page(s) e29416

    Abstract: The raising of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants led to the use of COVID-19 bivalent vaccines, which include antigens of the wild-type (WT) virus, and of the Omicron strain. In this study, we aimed to evaluate the ... ...

    Abstract The raising of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants led to the use of COVID-19 bivalent vaccines, which include antigens of the wild-type (WT) virus, and of the Omicron strain. In this study, we aimed to evaluate the impact of bivalent vaccination on the neutralizing antibody (NAb) response. We enrolled 93 volunteers who had received three or four doses of monovalent vaccines based on the original virus (n = 61), or a booster shot with the bivalent vaccine (n = 32). Serum samples collected from volunteers were subjected to neutralization assays using the WT SARS-CoV-2, and Omicron subvariants. In addition, immunoinformatics to quantify and localize highly conserved NAb epitopes were performed. As main result, we observed that the neutralization titers of samples from individuals vaccinated with the bivalent vaccine were higher for the original virus, in comparison to their capacity of neutralizing the Omicron variant and its subvariants. NAb that recognize epitopes mostly conserved in the WT SARS-CoV-2 were boosted, while those that recognize epitopes mostly present in the Omicron variant, and subvariants were primed. These results indicate that formulation of future vaccines shall consider to target present viruses, and not viruses that no longer circulate.
    MeSH term(s) Humans ; COVID-19 Vaccines ; COVID-19/prevention & control ; SARS-CoV-2/genetics ; Vaccination ; Immunization, Secondary ; Antibodies, Neutralizing ; Epitopes/genetics ; Vaccines, Combined
    Chemical Substances COVID-19 Vaccines ; Antibodies, Neutralizing ; Epitopes ; Vaccines, Combined
    Language English
    Publishing date 2024-01-02
    Publishing country United States
    Document type Journal Article
    ZDB-ID 752392-0
    ISSN 1096-9071 ; 0146-6615
    ISSN (online) 1096-9071
    ISSN 0146-6615
    DOI 10.1002/jmv.29416
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