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Article ; Online: Adverse effects, pharmacological interactions, and cardiovascular drugs in COVID-19 treatment.

Chuquiure-Valenzuela, Eduardo / Chuquiure-Valenzuela, Patricia / Chuquiure-Gil, María J / Bobadilla-Chuquiure, María P / Chuquiure-Valenzuela, Javier / Chuquiure-Lardizabal, Eduardo

Archivos de cardiologia de Mexico

2021 Volume 91, Issue Suplemento COVID, Page(s) 79–85

Abstract: In severe coronavirus disease (COVID)-19 patients, an extraordinary systemic inflammatory response is seen. It could impact in multiple organ disorders, specially a severe myocardial injury, an acute myocarditis results in focal or global myocardial ... ...

Abstract	In severe coronavirus disease (COVID)-19 patients, an extraordinary systemic inflammatory response is seen. It could impact in multiple organ disorders, specially a severe myocardial injury, an acute myocarditis results in focal or global myocardial inflammation and necrosis. Those events can be present in healthy subjects or cardiovascular (CV) patients. It is clinically associated with ventricular dysfunction exacerbation or worsening and tachyarrhythmias. It is also related to a poor outcome for CV patients with ischemic heart disease, hypertensión, and heart failure. COVID-19 patients require multiple and complex treatment that alleviates symptoms, the vast variety of agents interacts with diseases and CV drugs. Our purpose is to correlate in guidance synopsis: Adverse effects, pharmacological interactions, and CV drugs in COVID-19 treatment.
MeSH term(s)	Cardiovascular Agents/adverse effects ; Cardiovascular Agents/therapeutic use ; Cardiovascular Diseases/drug therapy ; Cardiovascular Diseases/virology ; Drug Interactions ; Humans ; Myocarditis/drug therapy ; Myocarditis/virology ; COVID-19 Drug Treatment
Chemical Substances	Cardiovascular Agents
Language	English
Publishing date	2021-12-20
Publishing country	Mexico
Document type	Journal Article
ZDB-ID	2059019-2
ISSN	1665-1731 ; 1665-1731
ISSN (online)	1665-1731
ISSN	1665-1731
DOI	10.24875/ACM.20000234
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Psychological distress and unsatisfied information needs in heart failure patients and ventricular dysfunction without previously diagnosed psychiatric disorder. Cross-sectional study in a national reference center

Silva-Ruz, Carlos / Martínez-Ríos, Marco A / Carbajal-Gutiérrez, Brenda / Fiscal-López, Óscar J / Chuquiure-Valenzuela, Eduardo / García-Romero, Daniel / Sánchez-Sosa, Juan J

Archivos de cardiologia de Mexico

2022 Volume 92, Issue 1, Page(s) 36–41

Abstract: Introduction: Heart failure (HF) is a chronic disease that acutely and progressively reduces physical functionality. The patient commonly suffers from intermittent relapses that increase the likelihood of comorbidities such as chronic insomnia, ... ...

Title translation	Distrés psicológico y necesidades de información insatisfechas en pacientes con insuficiencia cardiaca y disfunción ventricular sin trastorno psiquiátrico previamente diagnosticado. Estudio transversal en un centro de referencia nacional.
Abstract	Introduction: Heart failure (HF) is a chronic disease that acutely and progressively reduces physical functionality. The patient commonly suffers from intermittent relapses that increase the likelihood of comorbidities such as chronic insomnia, cognitive impairment, alterations in sexual response, psychological distress, symptoms of anxiety and depression disorder, and decreased self-care behaviors. The objective of this study was to identify the main needs for psychological support in patients with HF. Methodology: A descriptive, cross-sectional and analytical study was carried out. Participants were selected through consecutive non-probability samples. 150 patients with a diagnosis of HF who attended the Specialized Center for Heart Failure at the National Institute of Cardiology “Ignacio Chávez” were evaluated from November 2018 to April 2019, applying the inventories: Quality of life in patients with HF (Minnesota), Hospital Anxiety and Depression Scale (HADS), psychological distress thermometer (visual analog scale) and the HF Patient Information Needs Inventory. Results: 33% of the patients perceive a high level of psychological distress that requires immediate assistance and 26.6% report a medium level that requires monitoring. The main information needs reported by the patients were information on taking medications (53.7%) and managing psychological distress (43.9%). Conclusion: Active assessment of psychological distress and unmet information needs is relevant in patients with heart failure, thus highlighting the importance of their identification and the correct design and application of evidence-based interventions aimed at their resolution.
MeSH term(s)	Cross-Sectional Studies ; Heart Failure/complications ; Heart Failure/diagnosis ; Heart Failure/therapy ; Humans ; Mental Disorders ; Psychological Distress ; Quality of Life ; Surveys and Questionnaires ; Ventricular Dysfunction
Language	Spanish
Publishing date	2022-01-03
Publishing country	Mexico
Document type	Journal Article
ISSN	1665-1731
ISSN (online)	1665-1731
DOI	10.24875/ACM.200004531
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Article ; Online: Explaining the increment in coronary heart disease mortality in Mexico between 2000 and 2012.

Arroyo-Quiroz, Carmen / O'Flaherty, Martin / Guzman-Castillo, Maria / Capewell, Simon / Chuquiure-Valenzuela, Eduardo / Jerjes-Sanchez, Carlos / Barrientos-Gutierrez, Tonatiuh

PloS one

2020 Volume 15, Issue 12, Page(s) e0242930

Abstract: Background: Mexico is still in the growing phase of the epidemic of coronary heart disease (CHD), with mortality increasing by 48% since 1980. However, no studies have analyzed the drivers of these trends. We aimed to model CHD deaths between 2000 and ... ...

Abstract	Background: Mexico is still in the growing phase of the epidemic of coronary heart disease (CHD), with mortality increasing by 48% since 1980. However, no studies have analyzed the drivers of these trends. We aimed to model CHD deaths between 2000 and 2012 in Mexico and to quantify the proportion of the mortality change attributable to advances in medical treatments and to changes in population-wide cardiovascular risk factors. Methods: We performed a retrospective analysis using the previously validated IMPACT model to explain observed changes in CHD mortality in Mexican adults. The model integrates nationwide data at two-time points (2000 and 2012) to quantify the effects on CHD mortality attributable to changes in risk factors and therapeutic trends. Results: From 2000 to 2012, CHD mortality rates increased by 33.8% in men and by 22.8% in women. The IMPACT model explained 71% of the CHD mortality increase. Most of the mortality increases could be attributed to increases in population risk factors, such as diabetes (43%), physical inactivity (28%) and total cholesterol (24%). Improvements in medical and surgical treatments together prevented or postponed 40.3% of deaths; 10% was attributable to improvements in secondary prevention treatments following MI, while 5.3% to community heart failure treatments. Conclusions: CHD mortality in Mexico is increasing due to adverse trends in major risk factors and suboptimal use of CHD treatments. Population-level interventions to reduce CHD risk factors are urgently needed, along with increased access and equitable distribution of therapies.
MeSH term(s)	Adult ; Aged ; Aged, 80 and over ; Coronary Disease/epidemiology ; Coronary Disease/mortality ; Female ; Humans ; Male ; Mexico/epidemiology ; Middle Aged ; Mortality/trends ; Retrospective Studies ; Risk Factors ; Uncertainty
Language	English
Publishing date	2020-12-03
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2267670-3
ISSN	1932-6203 ; 1932-6203
ISSN (online)	1932-6203
ISSN	1932-6203
DOI	10.1371/journal.pone.0242930
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Article: Cardiometabolic risk factors and antithrombotic treatment in a Mexican population with atrial fibrillation and heart failure with reduced ejection fraction.

Baños-González, Manuel A / González-Hermosillo, Antonio / Guevara-Valdivia, Milton E / Vázquez-Acosta, Jorge A / de Los Ríos-Ibarra, Manuel O / Aguilar-Linares, Julio A / Cantú-Brito, Carlos / Leiva-Pons, José L / Pozas-Garza, Gerardo / Favela-Pérez, Eddie A / Molina, Luis / Magaña-Magaña, Reynaldo / Camacho-Casillas, Rocío / Chuquiure-Valenzuela, Eduardo / Manzano-Cabada, Janneth / Márquez-Murillo, Manlio F

Gaceta medica de Mexico

2023 Volume 159, Issue 1, Page(s) 24–31

Abstract: Introduction: Heart failure in patients with non-valvular atrial fibrillation (NVAF) is two to three times more common than in individuals without NVAF.: Objective: To identify cardiometabolic risk factors (CMRF) and antithrombotic treatment in ... ...

Title translation	Factores de riesgo cardiometabólico y tratamiento antitrombótico en población mexicana con fibrilación auricular e insuficiencia cardiaca con fracción de expulsión reducida.
Abstract	Introduction: Heart failure in patients with non-valvular atrial fibrillation (NVAF) is two to three times more common than in individuals without NVAF. Objective: To identify cardiometabolic risk factors (CMRF) and antithrombotic treatment in patients with NVAF and heart failure with reduced ejection fraction (HFrEF), and to determine if there were differences according to gender. Methods: CMRF, pro-thrombotic risk, bleeding risk, and antithrombotic therapy were globally analyzed and according to gender. Results: Out of 1,423 patients with NVAF, 336 had HFrEF. On average, females were older than males. There was no difference between genders with regard to the type of NVAF or direct oral anticoagulants use. Hypertension was more common in women. History of transient ischemic attack was reported in 3.6% of the patients and cerebrovascular event in 10%, without differences in terms of gender. The percentage of men with elevated embolic risk was higher, but without antithrombotic treatment, in comparison with women. Conclusions: Significant differences were found according to gender in patients with NVAF and HFrEF, both in CMRF and some comorbidities, as well as in antithrombotic treatment according to embolic and bleeding risk.
MeSH term(s)	Humans ; Male ; Female ; Atrial Fibrillation/complications ; Atrial Fibrillation/drug therapy ; Anticoagulants/adverse effects ; Fibrinolytic Agents/adverse effects ; Heart Failure/complications ; Heart Failure/drug therapy ; Heart Failure/epidemiology ; Cardiometabolic Risk Factors ; Stroke Volume ; Risk Factors ; Stroke/epidemiology ; Stroke/etiology ; Stroke/prevention & control
Chemical Substances	Anticoagulants ; Fibrinolytic Agents
Language	English
Publishing date	2023-03-17
Publishing country	Mexico
Document type	Journal Article
ZDB-ID	425456-9
ISSN	0016-3813
ISSN	0016-3813
DOI	10.24875/GMM.M22000738
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Article ; Online: Explaining the increment in coronary heart disease mortality in Mexico between 2000 and 2012.

Carmen Arroyo-Quiroz / Martin O'Flaherty / Maria Guzman-Castillo / Simon Capewell / Eduardo Chuquiure-Valenzuela / Carlos Jerjes-Sanchez / Tonatiuh Barrientos-Gutierrez

PLoS ONE, Vol 15, Iss 12, p e

2020 Volume 0242930

Abstract: Background Mexico is still in the growing phase of the epidemic of coronary heart disease (CHD), with mortality increasing by 48% since 1980. However, no studies have analyzed the drivers of these trends. We aimed to model CHD deaths between 2000 and ... ...

Abstract	Background Mexico is still in the growing phase of the epidemic of coronary heart disease (CHD), with mortality increasing by 48% since 1980. However, no studies have analyzed the drivers of these trends. We aimed to model CHD deaths between 2000 and 2012 in Mexico and to quantify the proportion of the mortality change attributable to advances in medical treatments and to changes in population-wide cardiovascular risk factors. Methods We performed a retrospective analysis using the previously validated IMPACT model to explain observed changes in CHD mortality in Mexican adults. The model integrates nationwide data at two-time points (2000 and 2012) to quantify the effects on CHD mortality attributable to changes in risk factors and therapeutic trends. Results From 2000 to 2012, CHD mortality rates increased by 33.8% in men and by 22.8% in women. The IMPACT model explained 71% of the CHD mortality increase. Most of the mortality increases could be attributed to increases in population risk factors, such as diabetes (43%), physical inactivity (28%) and total cholesterol (24%). Improvements in medical and surgical treatments together prevented or postponed 40.3% of deaths; 10% was attributable to improvements in secondary prevention treatments following MI, while 5.3% to community heart failure treatments. Conclusions CHD mortality in Mexico is increasing due to adverse trends in major risk factors and suboptimal use of CHD treatments. Population-level interventions to reduce CHD risk factors are urgently needed, along with increased access and equitable distribution of therapies.
Keywords	Medicine ; R ; Science ; Q
Subject code	310
Language	English
Publishing date	2020-01-01T00:00:00Z
Publisher	Public Library of Science (PLoS)
Document type	Article ; Online
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Article ; Online: Clinimetric analysis of heart failure in Mexican patients.

Chuquiure-Valenzuela, Eduardo / Fiscal-López, Oscar / García-Romero, Daniel / Chuquiure-Gil, María J / Silva-Ruz, Carlos / Aguilar-Moreno, Susana / Ordaz-Valdés, Mauricio / Méndez-Hernández, Gabriela / Hernández-Isidro, Nayelli / Jacobo-García, Karina / Cossio-Aranda, Jorge

Archivos de cardiologia de Mexico

2019 Volume 89, Issue 4, Page(s) 339–347

Abstract: Heart failure (HF) is a syndrome characterized basically by a circulatory deficit to cover the metabolic and energetic demands of the body. This condition has a broad spectrum in its clinical presentation, affects the quality of life significantly, ... ...

Title translation	Análisis clinimétrico de la insuficiencia cardiaca en pacientes mexicanos.
Abstract	Heart failure (HF) is a syndrome characterized basically by a circulatory deficit to cover the metabolic and energetic demands of the body. This condition has a broad spectrum in its clinical presentation, affects the quality of life significantly, impacts the family/social environment, and generates a great demand for health services. The purpose of this research is to report the situational diagnose of patients with HF in Mexico. We evaluated 292 patients, 70.2% were men. Average age was 56.7 ± 14.3 years. Ischemic heart disease is the main etiology (98 patients, 33.9%) followed by hypertensive (22.6%) and idiopathic (23.3%) heart disease. The associated clinical background was obesity (31.1%), systemic hypertension (36.7%), myocardial infarction (26.4%), and dyslipidemia (15.1%). The most common symptom was stress dyspnea (41.4%) and jugular vein engorgement at physical examination (32.5%). Anemia was observed in 1% of patients. The average left ventricular ejection fraction was 29.2 ± 10.6%. Sinus rhythm was the most frequently detected in 84.9%. 19.9% of patients had an implantable cardioverter-defibrillator or cardiac resynchronization therapy. 13.7% of patients with QRS > 130 ms. In our population, the meta-analysis global group in chronic heart failure risk score calculated was 16.8 ± 5.7 and for EMPHASIS 3.3 ± 1.5. We observed that age at presentation in HF in this analysis is at least 10 years younger than in other reports. The grade of obesity takes relevance in our group. The association of anemia and HF in Mexico is rare.
MeSH term(s)	Adolescent ; Adult ; Aged ; Aged, 80 and over ; Anemia/epidemiology ; Cardiac Resynchronization Therapy/statistics & numerical data ; Defibrillators, Implantable/statistics & numerical data ; Female ; Heart Failure/epidemiology ; Heart Failure/physiopathology ; Heart Failure/therapy ; Humans ; Male ; Mexico/epidemiology ; Middle Aged ; Obesity/epidemiology ; Quality of Life ; Stroke Volume ; Young Adult
Language	English
Publishing date	2019-12-27
Publishing country	Mexico
Document type	Journal Article
ISSN	1665-1731
ISSN (online)	1665-1731
DOI	10.24875/ACM.M19000054
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Article ; Online: Characteristics and 2-year outcomes of dabigatran treatment in patients with heart failure and atrial fibrillation: GLORIA-AF.

Dubner, Sergio J / Teutsch, Christine / Huisman, Menno V / Diener, Hans-Christoph / Halperin, Jonathan / Rothman, Kenneth J / Ma, Chang-Sheng / Chuquiure-Valenzuela, Eduardo / Bergler-Klein, Jutta / Zint, Kristina / Riou França, Lionel / Lu, Shihai / Paquette, Miney / Lip, Gregory Y H

ESC heart failure

2020 Volume 7, Issue 5, Page(s) 2679–2689

Abstract: Aims: This study aimed to describe baseline characteristics of patients with atrial fibrillation (AF) at risk of stroke with and without history of heart failure (HF) and report 2-year outcomes in the dabigatran-treated subset of a prospective, global, ... ...

Abstract	Aims: This study aimed to describe baseline characteristics of patients with atrial fibrillation (AF) at risk of stroke with and without history of heart failure (HF) and report 2-year outcomes in the dabigatran-treated subset of a prospective, global, observational study (GLORIA-AF). Methods and results: Newly diagnosed patients with AF and CHA Conclusions: Patients with AF and history of HF may have greater disease burden at AF diagnosis and increased mortality rates vs. patients without HF. Stroke and major bleeding rates were roughly comparable between groups confirming the long-term safety and effectiveness of dabigatran in patients with HF.
MeSH term(s)	Atrial Fibrillation/complications ; Atrial Fibrillation/drug therapy ; Atrial Fibrillation/epidemiology ; Dabigatran ; Heart Failure/complications ; Heart Failure/drug therapy ; Heart Failure/epidemiology ; Humans ; Prospective Studies ; Stroke/epidemiology ; Stroke/etiology ; Stroke/prevention & control
Chemical Substances	Dabigatran (I0VM4M70GC)
Keywords	covid19
Language	English
Publishing date	2020-07-02
Publishing country	England
Document type	Journal Article ; Observational Study ; Research Support, Non-U.S. Gov't
ZDB-ID	2814355-3
ISSN	2055-5822 ; 2055-5822
ISSN (online)	2055-5822
ISSN	2055-5822
DOI	10.1002/ehf2.12857
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Article ; Online: Correction: Management of Cardiovascular Disease Patients With Confirmed or Suspected COVID-19 in Limited Resource Settings.

Global heart

2020 Volume 15, Issue 1, Page(s) 54

Abstract: This corrects the article DOI: 10.5334/gh.823.]. ...

Abstract	[This corrects the article DOI: 10.5334/gh.823.].
Keywords	covid19
Language	English
Publishing date	2020-08-07
Publishing country	England
Document type	Journal Article ; Published Erratum
ZDB-ID	2629633-0
ISSN	2211-8179 ; 2211-8160
ISSN (online)	2211-8179
ISSN	2211-8160
DOI	10.5334/gh.885
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Article ; Online: Cardiometabolic risk factors and antithrombotic treatment in a Mexican population with atrial fibrillation and heart failure with reduced ejection fraction

Manuel A. BaÃ±os-GonzÃ¡lez / Antonio GonzÃ¡lez-Hermosillo / Milton E. Guevara-Valtier / Jorge A. VÃ¡zquez-Acosta / Manuel O. de los RÃos-Ibarra / Julio A. Aguilar-Linares / Carlos CantÃº-Brito / JosÃ© L. Leiva-Pons / Gerardo Pozas-Garza / Eddie A. Favela-PÃ©rez / Luis Molina / Reynaldo MagaÃ±a-MagaÃ±a / RocÃo Camacho-Casillas / Eduardo Chuquiure-Valenzuela / Janneth Manzano-Cabada / Manlio F. MÃ¡rquez-Murillo

Gaceta Médica de México, Vol 159, Iss

2023 Volume 1

Abstract: Introduction: Heart failure in patients with non-valvular atrial fibrillation (NVAF) is two to three times more common than in individuals without NVAF. Objective: To identify cardiometabolic risk factors (CMRF) and antithrombotic treatment in patients ... ...

Abstract	Introduction: Heart failure in patients with non-valvular atrial fibrillation (NVAF) is two to three times more common than in individuals without NVAF. Objective: To identify cardiometabolic risk factors (CMRF) and antithrombotic treatment in patients with NVAF and heart failure with reduced ejection fraction (HFrEF), and to determine if there were differences according to gender. Methods: CMRF, pro-thrombotic risk, bleeding risk, and antithrombotic therapy were globally analyzed and according to gender. Results: Out of 1,423 patients with NVAF, 336 had HFrEF. On average, females were older than males. There was no difference between genders with regard to the type of NVAF or direct oral anticoagulants use. Hypertension was more common in women. History of transient ischemic attack was reported in 3.6% of the patients and cerebrovascular event in 10%, without differences in terms of gender. The percentage of men with elevated embolic risk was higher, but without antithrombotic treatment, in comparison with women. Conclusions: Significant differences were found according to gender in patients with NVAF and HFrEF, both in CMRF and some comorbidities, as well as in antithrombotic treatment according to embolic and bleeding risk.
Keywords	Anticoagulants. Risk factors. Atrial fibrillation. Heart failure. Mexico ; Public aspects of medicine ; RA1-1270 ; Internal medicine ; RC31-1245
Subject code	610
Language	English
Publishing date	2023-01-01T00:00:00Z
Publisher	Permanyer
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Management of Cardiovascular Disease Patients With Confirmed or Suspected COVID-19 in Limited Resource Settings.

Global heart

2020 Volume 15, Issue 1, Page(s) 44

Abstract: In this paper, we provide recommendations on the management of cardiovascular disease (CVD) among patients with confirmed or suspected coronavirus disease (COVID-19) to facilitate the decision making of healthcare professionals in low resource settings. ... ...

Abstract	In this paper, we provide recommendations on the management of cardiovascular disease (CVD) among patients with confirmed or suspected coronavirus disease (COVID-19) to facilitate the decision making of healthcare professionals in low resource settings. The emergence of novel coronavirus disease, also known as Severe Acute Respiratory Syndrome-Coronavirus-2 (SARS-CoV-2), has presented an unprecedented global challenge for the healthcare community. The ability of SARS-CoV-2 to get transmitted during the asymptomatic phase and its high infectivity have led to the rapid transmission of COVID-19 beyond geographic regions, leading to a pandemic. There is concern that COVID-19 is cardiotropic, and it interacts with the cardiovascular system on multiple levels. Individuals with established CVD are more susceptible to severe COVID-19. Through a consensus approach involving an international group this WHF statement summarizes the links between cardiovascular disease and COVID-19 and present some practical recommendations for the management of hypertension and diabetes, acute coronary syndrome, heart failure, rheumatic heart disease, Chagas disease, and myocardial injury for patients with COVID-19 in low-resource settings. This document is not a clinical guideline and it is not intended to replace national clinical guidelines or recommendations. Given the rapidly growing burden posed by COVID-19 illness and the associated severe prognostic implication of CVD involvement, further research is required to understand the potential mechanisms linking COVID-19 and CVD, clinical presentation, and outcomes of various cardiovascular manifestations in COVID-19 patients.
MeSH term(s)	COVID-19 ; Cardiovascular Diseases/complications ; Cardiovascular Diseases/therapy ; Clinical Decision-Making ; Coronavirus Infections/complications ; Decision Trees ; Health Resources ; Humans ; Pandemics ; Pneumonia, Viral/complications ; Practice Guidelines as Topic
Keywords	covid19
Language	English
Publishing date	2020-07-01
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2629633-0
ISSN	2211-8179 ; 2211-8160
ISSN (online)	2211-8179
ISSN	2211-8160
DOI	10.5334/gh.823
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