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  1. Book ; Online ; E-Book: Atlas of Hysteroscopy

    Tinelli, Andrea / Alonso Pacheco, Luis / Haimovich, Sergio

    2020  

    Abstract: This book provides a wealth of detailed hysteroscopic images, illustrating the various gynecological pathologies that can be directly diagnosed by hysteroscopy. Providing comprehensive coverage, the book examines each pathology on the basis of concrete ... ...

    Author's details edited by Andrea Tinelli, Luis Alonso Pacheco, Sergio Haimovich
    Abstract This book provides a wealth of detailed hysteroscopic images, illustrating the various gynecological pathologies that can be directly diagnosed by hysteroscopy. Providing comprehensive coverage, the book examines each pathology on the basis of concrete images, offering readers support with the diagnostic evaluation. This is especially important when there are recrudescent pathologies, such as TBC, which can often confuse physicians in the context of diagnosis, and with regard to oncological, infectious and infertility issues. Written by prominent experts in the field, this atlas offers an extremely useful and comprehensive tool for all gynecologists, which can support them to overcome any diagnostic doubts and arrive at an accurate diagnosis.
    Keywords Gynecology  ; Oncology   ; Pathology ; Gynecology ; Oncology
    Subject code 618.1407545
    Language English
    Size 1 online resource (VI, 230 p. 529 illus., 527 illus. in color.)
    Edition 1st ed. 2020.
    Publisher Springer International Publishing ; Imprint: Springer
    Publishing place Cham
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    ISBN 3-030-29466-8 ; 3-030-29465-X ; 978-3-030-29466-3 ; 978-3-030-29465-6
    DOI 10.1007/978-3-030-29466-3
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Book ; Online: Eco-Friendly Materials for Civil Construction

    Fontes Vieira, Carlos Maurício / de Castro Xavier, Gustavo / Colorado Lopera, Henry Alonso / Monteiro, Sergio Neves

    Utilization and Advantages

    2023  

    Keywords Technology: general issues ; History of engineering & technology ; ubim fiber ; natural lignocellulosic fiber ; X-ray diffraction ; density ; morphology characterization ; waste tires ; molasses ; soil improving ; cements ; materials ; sustainability ; construction ; civil engineering ; phases ; castor oil polyurethane ; natural fiber biocomposite ; piassava fiber powder ; high-performance coating ; high-performance coating floor ; ornamental rock waste ; projected mortar ; life cycle assessment ; squeeze flow ; cement ; thermoelectric modules ; cost-efficiency ratio ; life cycle ; circular economy ; artificial stone ; vegetable polyurethane ; granite waste ; quartzite ; resin ; coating ; solid waste ; construction and demolition ; engineered stone ; wastes ; waste glass ; quartz ; epoxy resin ; glass waste ; sand ; liquid phase ; reuse ; low-cost GFRP ; square ; recycled brick aggregate ; regression
    Language English
    Size 1 electronic resource (230 pages)
    Publisher MDPI - Multidisciplinary Digital Publishing Institute
    Publishing place Basel
    Document type Book ; Online
    Note English
    HBZ-ID HT030377926
    ISBN 9783036570860 ; 3036570861
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  3. Book ; Online: CITIES: Energetic Efficiency, Sustainability; Infrastructures, Energy and the Environment; Mobility and IoT; Governance and Citizenship

    Hernández-Callejo, Luis / Gómez, Víctor Alonso / Nesmachnow, Sergio / Leite, Vicente / Prieto, Javier / Ferreira, Ângela

    2021  

    Keywords Technology: general issues ; electric buses ; public transportation ; PV supplied sustainable transportation ; digitization ; knowledge sharing ; human resources management ; competitiveness ; Industry 4.0 ; home energy management ; Zigbee ; smart socket ; monitoring ; appliances scheduling ; urban mobility ; data analysis ; origin-destination ; ITS ; tall building ; locating criteria ; fuzzy visibility ; visual impact ; water accounting ; resource efficiencies ; virtual water trade ; Australian trade sustainability ; sustainable resource management ; governance-engineering nexus ; smart mobility ; demand responsive transport ; connected and autonomous vehicle ; Mobility-as-a-Service (MaaS) ; electric mobility ; shared transportation ; intelligent transportation systems ; smart city ; transportation disadvantage ; social exclusion ; Android application ; energy-efficient ; mobile ads ; gamma correction ; energy performance certificate (EPC) ; hedonic pricing method ; real estate market ; property prices ; Alicante ; DIALux ; simulation ; lighting quality ; teaching institution ; classroom lighting ; flood risk management ; measures ; approaches ; design criteria ; plans ; schemes ; hazard ; vulnerability ; risk ; expected annual damages ; direct and indirect flood losses ; computational intelligence ; image processing ; pedestrian movement patterns ; surveillance cameras ; cost-benefit analysis ; multicriteria analysis ; comparative risk assessment ; economic rent ; internal rate of return ; present value ; optimal risk point ; flood management ratio ; photovoltaic cell defect ; classifier ; artificial intelligence ; traffic congestion ; public urban transport ; daily infections by COVID-19 ; flood ; integrated flood risk management ; resilience building ; emergency planning ; disaster risk reduction ; community participation ; disaster preparedness ; environmental footprint ; cleanup ; green remediation ; renewable energy sources ; smart microgrid ; Home Assistant ; monitoring and control system ; older adults ; mobility ; systematic review ; municipal electric bike system ; electric bike-sharing ; sustainable urban transport ; travel behavior ; timetable synchronization ; public transportation planning ; mixed integer programming ; evolutionary algorithms ; real case study ; smart cities ; battery energy storage system ; dimensioning methodology ; industrial consumption ; electricity fixed term ; demand response ; smart grid ; discomfort index ; water heaters ; thermal model
    Size 1 electronic resource (480 pages)
    Publisher MDPI - Multidisciplinary Digital Publishing Institute
    Publishing place Basel, Switzerland
    Document type Book ; Online
    Note English ; Open Access
    HBZ-ID HT021291698
    ISBN 9783036527444 ; 3036527443
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  4. Article: Antiproliferative and cytotoxic effects of grape pomace and grape seed extracts on colorectal cancer cell lines

    PÉREZ-ORTIZ, JOSÉ M. / Gómez-Alonso, Sergio

    Food Science & Nutrition, 7(9):2948-2957

    2019  

    Abstract: Grape pomace is the source of bioactive compounds (anthocyanins, flavonols, flavan‐3‐ols, and stilbenes) which exhibit antiproliferative actions on cell cultures. We have investigated the antitumoral effects of grape pomace and grape seed extracts on ... ...

    Abstract Grape pomace is the source of bioactive compounds (anthocyanins, flavonols, flavan‐3‐ols, and stilbenes) which exhibit antiproliferative actions on cell cultures. We have investigated the antitumoral effects of grape pomace and grape seed extracts on colon cancer cells (Caco‐2, HT‐29) and fibroblasts. Crude extracts prepared from white and red pomace, and grape seeds, reduced the viability and proliferation of Caco‐2. HT‐29 cells were resistant to these actions. Purified extracts were then prepared from the same sources and compared with the LDH test; again, all three extracts were active and purified extract from grape seed was the most potent and specific on Caco‐2 cells. HT‐29 cells were more sensitive to these purified extracts. The biological activity resided almost exclusively in the flavonol and flavan‐3‐ols subfractions, rather than the anthocyanin subfraction. Preliminary results on the mechanisms involved in these effects revealed downregulation of Myc gene expression in HT‐29 and upregulation of Ptg2 in Caco‐2 cells.
    Keywords Caco‐2 ; HT‐29 ; antitumoral ; grape extracts
    Language English
    Document type Article
    Database Repository for Life Sciences

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  5. Article ; Online: Móvil a pie de cama para unos cuidados de calidad

    Sergio Romeo López Alonso

    NURE Investigación, Vol 20, Iss

    2023  Volume 123

    Abstract: Como se adelantó en las Conclusiones del VII Encuentro con Editores de Revistas Científicas de Enfermería, en la actualidad, persisten las dificultades que presentan las enfermeras clínicas para acceder al conocimiento disciplinar generado a través de la ...

    Abstract Como se adelantó en las Conclusiones del VII Encuentro con Editores de Revistas Científicas de Enfermería, en la actualidad, persisten las dificultades que presentan las enfermeras clínicas para acceder al conocimiento disciplinar generado a través de la investigación y publicado en las revistas destinadas a tal fin. Estas dificultades de acceso al conocimiento pueden suponer una importante merma en la calidad de los cuidados que proporcionan las enfermeras a la población; ya que dicha calidad va ligada necesariamente a la última investigación disponible. Fue precisamente esta traslación del conocimiento a la práctica, la base que fundamentó, en su momento, el movimiento hacia la práctica clínica basada en evidencias. En este sentido, las preguntas clínicas suelen surgir de un encuentro enfermera-paciente en un contexto sanitario, siendo muchas veces necesaria su respuesta en un tiempo relativamente inmediato, bien sea por la sobrecarga asistencial o por la urgencia del problema.
    Keywords Teléfono Celular ; Aplicaciones Móviles ; Motor de Búsqueda ; Inteligencia Artificial ; Enfermería Basada en la Evidencia ; Medicine ; R ; Nursing ; RT1-120
    Language Spanish
    Publishing date 2023-04-01T00:00:00Z
    Publisher Fundación para el Desarrollo de la Enfermería
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article ; Online: Letter to the Editor: Intracorporeal anastomosis versus extracorporeal anastomosis in laparoscopic right colectomy: An observational cohort study.

    Tustumi, Francisco / Araujo, Sergio Eduardo Alonso

    World journal of surgery

    2023  Volume 48, Issue 4, Page(s) 989

    MeSH term(s) Humans ; Colectomy ; Anastomosis, Surgical ; Laparoscopy ; Cohort Studies ; Colonic Neoplasms/surgery ; Treatment Outcome ; Retrospective Studies
    Language English
    Publishing date 2023-12-10
    Publishing country United States
    Document type Observational Study ; Letter
    ZDB-ID 224043-9
    ISSN 1432-2323 ; 0364-2313
    ISSN (online) 1432-2323
    ISSN 0364-2313
    DOI 10.1002/wjs.12039
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1336: Show issues Location:
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  7. Article ; Online: "Cyclist at 12 o'clock!": a systematic review of in-vehicle advanced driver assistance systems (ADAS) for preventing car-rider crashes.

    Useche, Sergio A / Faus, Mireia / Alonso, Francisco

    Frontiers in public health

    2024  Volume 12, Page(s) 1335209

    Abstract: Introduction: While Advanced Driver Assistance Systems (ADAS) have become a prominent topic in road safety research, there has been relatively little discussion about their effectiveness in preventing car collisions involving specific vulnerable road ... ...

    Abstract Introduction: While Advanced Driver Assistance Systems (ADAS) have become a prominent topic in road safety research, there has been relatively little discussion about their effectiveness in preventing car collisions involving specific vulnerable road users, such as cyclists. Therefore, the primary objective of this systematic literature review is to analyze the available evidence regarding the effectiveness of in-vehicle ADAS in preventing vehicle collisions with cyclists.
    Methods: To achieve this goal, this systematic review analyzed a selection of original research papers that examined the effectiveness of ADAS systems in preventing car-cyclist collisions. The review followed the PRISMA protocol, which led to the extraction of 21 eligible studies from an initial pool of 289 sources indexed in the primary scientific literature databases. Additionally, word community-based content analyses were used to examine the research topics and their links within the current scientific literature on the matter.
    Results: Although the current number of studies available is still scarce (most sources focus on car-motorcyclist or car-pedestrian crashes), the overall quality of the available studies has been reasonably good, as determined by the selected evaluation methods. In terms of studies' outcomes, the literature supports the value of in-vehicle ADAS for preventing car-cyclist crashes. However, threatful side effects such as unrealistic expectations of these systems and users' overconfidence or desensitization are also highlighted, as well as the need to increase driver training and road user awareness.
    Conclusion: The results of this study suggest that Advanced Driver Assistance Systems have significant potential to contribute to the prevention of driving crashes involving cyclists. However, the literature emphasizes the importance of concurrently enhancing user-related skills in both ADAS use and road-user interaction through educational and training initiatives. Future research should also address emerging issues, such as ADAS-related behavioral ergonomics, and conduct long-term effectiveness assessments of ADAS in preventing car-cycling crashes and their subsequent injuries.
    Systematic review registration: PROSPERO, unique identifier CRD42024505492, https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=505492.
    MeSH term(s) Accidents, Traffic/prevention & control ; Automobiles ; Bicycling ; Databases, Factual ; Educational Status
    Language English
    Publishing date 2024-02-19
    Publishing country Switzerland
    Document type Journal Article ; Systematic Review
    ZDB-ID 2711781-9
    ISSN 2296-2565 ; 2296-2565
    ISSN (online) 2296-2565
    ISSN 2296-2565
    DOI 10.3389/fpubh.2024.1335209
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Mechanisms of adaptation and evolution in Toxoplasma gondii.

    Angel, Sergio O / Vanagas, Laura / Alonso, Andres M

    Molecular and biochemical parasitology

    2024  Volume 258, Page(s) 111615

    Abstract: Toxoplasma has high host flexibility, infecting all nucleated cells of mammals and birds. This implies that during its infective process the parasite must constantly adapt to different environmental situations, which in turn leads to modifications in its ...

    Abstract Toxoplasma has high host flexibility, infecting all nucleated cells of mammals and birds. This implies that during its infective process the parasite must constantly adapt to different environmental situations, which in turn leads to modifications in its metabolism, regulation of gene transcription, translation of mRNAs and stage specific factors. There are conserved pathways that support these adaptations, which we aim to elucidate in this review. We begin by exploring the widespread epigenetic mechanisms and transcription regulators, continue with the supportive role of Heat Shock Proteins (Hsp), the translation regulation, stress granules, and finish with the emergence of contingency genes in highly variable genomic domains, such as subtelomeres. Within epigenetics, the discovery of a new histone variant of the H2B family (H2B.Z), contributing to T. gondii virulence and differentiation, but also gene expression regulation and its association with the metabolic state of the parasite, is highlighted. Associated with the regulation of gene expression are transcription factors (TFs). An overview of the main findings on TF and development is presented. We also emphasize the role of Hsp90 and Tgj1 in T. gondii metabolic fitness and the regulation of protein translation. Translation regulation is also highlighted as a mechanism for adaptation to conditions encountered by the parasite as well as stress granules containing mRNA and proteins generated in the extracellular tachyzoite. Another important aspect in evolution and adaptability are the subtelomeres because of their high variability and gene duplication rate. Toxoplasma possess multigene families of membrane proteins and contingency genes that are associated with different metabolic stresses. Among them parasite differentiation and environmental stresses stand out, including those that lead tachyzoite to bradyzoite conversion. Finally, we are interested in positioning protozoa as valuable evolution models, focusing on research related to the Extended Evolutionary Synthesis, based on models recently generated, such as extracellular adaptation and ex vivo cyst recrudescence.
    MeSH term(s) Toxoplasma/genetics ; Toxoplasma/metabolism ; Toxoplasma/growth & development ; Adaptation, Physiological ; Animals ; Epigenesis, Genetic ; Protozoan Proteins/genetics ; Protozoan Proteins/metabolism ; Gene Expression Regulation ; Humans ; Biological Evolution ; Transcription Factors/genetics ; Transcription Factors/metabolism ; Evolution, Molecular
    Chemical Substances Protozoan Proteins ; Transcription Factors
    Language English
    Publishing date 2024-02-13
    Publishing country Netherlands
    Document type Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 756166-0
    ISSN 1872-9428 ; 0166-6851
    ISSN (online) 1872-9428
    ISSN 0166-6851
    DOI 10.1016/j.molbiopara.2024.111615
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  9. Article: Proteomics Applications in

    Deng, Bin / Vanagas, Laura / Alonso, Andres M / Angel, Sergio O

    Pathogens (Basel, Switzerland)

    2023  Volume 13, Issue 1

    Abstract: Toxoplasma ... ...

    Abstract Toxoplasma gondii
    Language English
    Publishing date 2023-12-29
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2695572-6
    ISSN 2076-0817
    ISSN 2076-0817
    DOI 10.3390/pathogens13010033
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  10. Article: The Challenge of Learning New Techniques in Minimally Invasive Colon and Rectal Surgery.

    Araujo, Sergio Eduardo Alonso

    Clinics in colon and rectal surgery

    2021  Volume 34, Issue 3, Page(s) 129–130

    Language English
    Publishing date 2021-03-29
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2048635-2
    ISSN 1531-0043
    ISSN 1531-0043
    DOI 10.1055/s-0040-1718689
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    Zs.A 3931: Show issues Location:
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