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  1. Article ; Online: Adipose Tissue Metabolism in Response to Food Intake.

    Carrillo, Andres E / Vliora, Maria

    Nutrients

    2023  Volume 15, Issue 22

    Abstract: The quality and quantity of the food we consume have a major impact on our general health and longevity [ ... ]. ...

    Abstract The quality and quantity of the food we consume have a major impact on our general health and longevity [...].
    MeSH term(s) Adipose Tissue/metabolism ; Eating/physiology
    Language English
    Publishing date 2023-11-17
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2518386-2
    ISSN 2072-6643 ; 2072-6643
    ISSN (online) 2072-6643
    ISSN 2072-6643
    DOI 10.3390/nu15224811
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  2. Article ; Online: Cardiac autonomic modulation in individuals with controlled and uncomplicated hypertension during exercise-heat stress.

    Carrillo, Andres E / Akerman, Ashley P / Notley, Sean R / Herry, Christophe L / Seely, Andrew J E / Ruzicka, Marcel / Boulay, Pierre / Kenny, Glen P

    Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme

    2023  Volume 48, Issue 11, Page(s) 863–869

    Abstract: Take-home message: During short bouts of light-to-vigorous exercise in the heat, controlled and uncomplicated hypertension did not significantly modulate HRV in physically active individuals. These findings can be used to refine guidance on use of ... ...

    Abstract Take-home message: During short bouts of light-to-vigorous exercise in the heat, controlled and uncomplicated hypertension did not significantly modulate HRV in physically active individuals. These findings can be used to refine guidance on use of exercise for hypertension management in the heat.
    MeSH term(s) Humans ; Heart Rate ; Heart ; Hypertension/therapy ; Autonomic Nervous System ; Heat-Shock Response ; Heat Stress Disorders
    Language English
    Publishing date 2023-08-09
    Publishing country Canada
    Document type Journal Article
    ZDB-ID 2236708-1
    ISSN 1715-5320 ; 1715-5312
    ISSN (online) 1715-5320
    ISSN 1715-5312
    DOI 10.1139/apnm-2023-0173
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1717: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (1.OG)
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  3. Article ; Online: Correlates of estimated lifetime cruciate ligament survival inform potential rupture risk reduction strategies: findings from the Exceptional Aging in Rottweilers Study.

    Waters, David J / Fu, Rong / Carrillo, Andres E / Chiang, Emily C / Maras, Aimee H / Kengeri, Seema S / Suckow, Cheri L

    Scientific reports

    2023  Volume 13, Issue 1, Page(s) 13920

    Abstract: Cranial cruciate ligament (CCL) rupture is one of the most commonly diagnosed orthopedic conditions of pet dogs, making estimated lifetime cruciate ligament survival an attractive endpoint for studies attempting to define clinical and genetic correlates ... ...

    Abstract Cranial cruciate ligament (CCL) rupture is one of the most commonly diagnosed orthopedic conditions of pet dogs, making estimated lifetime cruciate ligament survival an attractive endpoint for studies attempting to define clinical and genetic correlates of rupture risk reduction. Early life experiences contribute significantly to the origins of adult health outcomes, yet our current understanding of modifiable susceptibility factors that drive the high frequency of CCL rupture remains limited. We reasoned that combining lifetime medical history with standardized late-life assessment of lifetime cruciate ligament survival and detailed phenotyping of each dog for selected risk variables would provide a sensitive approach to identify factors that would differentiate between lifelong avoidance versus susceptibility to ligament rupture. Here, we report results of Kaplan-Meier analysis of estimated lifetime cruciate ligament survival and Cox proportional hazards modeling to assess risk variables in a lifetime cohort study of 123 purebred Rottweilers, a breed at high risk for veterinarian-diagnosed CCL rupture. We show that gonad removal during the 24-month developmental period is adversely associated with three measures of susceptibility-increased incidence of CCL rupture, multiplicity (bilateral rupture), and accelerated time to initial CCL failure. Our analysis reveals two other phenotypes-short adult height and the production of offspring (in females)-are associated with significant CCL rupture risk reduction. Together, the results provide clues to an early endocrine influence on lifetime cruciate ligament survival. Further, we identify two distinct clinical syndromes of CCL failure, providing a disease subtyping framework to advance future progress in genetic epidemiology, pathogenesis, and prediction. By conducting an evaluation of estimated lifetime CCL survival in dogs, we show that cruciate ligament survival may be jeopardized by gonad removal during the developmental period. Avoidance of such early environmental adversity may represent an actionable method for the control of canine CCL disease in certain breeds.
    MeSH term(s) Female ; Dogs ; Animals ; Cohort Studies ; Ligaments, Articular ; Risk Reduction Behavior ; Aging ; Anterior Cruciate Ligament Injuries ; Dog Diseases
    Language English
    Publishing date 2023-08-25
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-023-39288-y
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  4. Article ; Online: In-stent restenosis percutaneous coronary intervention after chimney stenting during transcatheter aortic valve-in-valve implantation.

    Andrés-Cordón, Joan F / Armario, Xavier / Fernández-Nofrerias, Eduard / Carrillo, Xavier / Rodríguez-Leor, Oriol

    EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology

    2023  Volume 19, Issue 2, Page(s) e191–e192

    MeSH term(s) Humans ; Aortic Valve/diagnostic imaging ; Aortic Valve/surgery ; Coronary Restenosis ; Stents ; Percutaneous Coronary Intervention/adverse effects ; Transcatheter Aortic Valve Replacement/adverse effects ; Aortic Valve Stenosis/surgery ; Treatment Outcome ; Heart Valve Prosthesis
    Language English
    Publishing date 2023-06-05
    Publishing country France
    Document type Journal Article
    ZDB-ID 2457174-X
    ISSN 1969-6213 ; 1774-024X
    ISSN (online) 1969-6213
    ISSN 1774-024X
    DOI 10.4244/EIJ-D-22-00891
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6680: Show issues Location:
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    Zs.MO 571: Show issues

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  5. Article: Elevated Inflammatory Status and Increased Risk of Chronic Disease in Chronological Aging: Inflamm-aging or

    Flynn, Michael G / Markofski, Melissa M / Carrillo, Andres E

    Aging and disease

    2019  Volume 10, Issue 1, Page(s) 147–156

    Abstract: Age-associated hyper-inflammation or "inflamm-aging" has been linked to the development of chronic diseases and characterized as an unavoidable aspect of aging. However, the inflamm-aging model does not adequately address the potential anti-inflammatory ... ...

    Abstract Age-associated hyper-inflammation or "inflamm-aging" has been linked to the development of chronic diseases and characterized as an unavoidable aspect of aging. However, the inflamm-aging model does not adequately address the potential anti-inflammatory effects of exercise training and the potential for exercise to ameliorate several age-related diseases. In this brief review, we introduce a new paradigm-
    Language English
    Publishing date 2019-02-01
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2625789-0
    ISSN 2152-5250
    ISSN 2152-5250
    DOI 10.14336/AD.2018.0326
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  6. Article ; Online: Assessing the cadmium content of cacao crops in Arauca, Colombia.

    Bravo, Daniel / Quiroga-Mateus, Ruth / López-Casallas, Marcela / Torres, Shirley / Contreras, Ramiro / Otero, Andres Camilo Mendez / Araujo-Carrillo, Gustavo A / González-Orozco, Carlos E

    Environmental monitoring and assessment

    2024  Volume 196, Issue 4, Page(s) 387

    Abstract: The district of Arauca is the second-largest producer of cacao in Colombia. However, despite its quality, it faces issues for export due to levels of cadmium (Cd) higher than the regulatory thresholds. A central question is how it may impact agricultural ...

    Abstract The district of Arauca is the second-largest producer of cacao in Colombia. However, despite its quality, it faces issues for export due to levels of cadmium (Cd) higher than the regulatory thresholds. A central question is how it may impact agricultural performance in the presence of Cd in cacao and chocolates. This study quantified Cd in cacao plantations from Arauca. Thus, 180 farms were assessed in the municipalities of Arauquita, Fortul, Saravena, and Tame. Five sample types (soil, irrigation channel sediment, soil litter, cacao seeds, and chocolates) were assessed for Cd. As a technological innovation, the new MXRF technology was used for Cd in chocolates. The sequence of Cd content was soil litter > chocolate > soils > cacao seeds > irrigation-channel sediment. A gradient north-south of Cd content in soil was observed, where highest content was found in farms near the Arauca River, and lower farther away. In irrigation channel sediment, Cd levels averaged 0.07 mg kg
    MeSH term(s) Cadmium/analysis ; Cacao ; Colombia ; Environmental Monitoring ; Soil Pollutants/analysis ; Soil ; Crops, Agricultural
    Chemical Substances Cadmium (00BH33GNGH) ; Soil Pollutants ; Soil
    Language English
    Publishing date 2024-03-21
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 782621-7
    ISSN 1573-2959 ; 0167-6369
    ISSN (online) 1573-2959
    ISSN 0167-6369
    DOI 10.1007/s10661-024-12539-9
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    In stock of ZB MED Bonn / Germany

    Z 5186: Show issues

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  7. Article ; Online: Effects of Alpha-lipoic Acid Supplementation on Human Diabetic Nephropathy: A Systematic Review and Meta-analysis.

    Vakali, Elena / Rigopoulos, Dimitrios / Carrillo, Andres E / Flouris, Andreas D / Dinas, Petros C

    Current diabetes reviews

    2021  Volume 18, Issue 6, Page(s) e140921196457

    Abstract: Background: Diabetic nephropathy (DN) is kidney dysfunction, which occurs due to elevated urine albumin excretion rate and reduced glomerular filtration rate. Studies on animals have shown that alpha-lipoic acid (ALA) supplementation can reduce the ... ...

    Abstract Background: Diabetic nephropathy (DN) is kidney dysfunction, which occurs due to elevated urine albumin excretion rate and reduced glomerular filtration rate. Studies on animals have shown that alpha-lipoic acid (ALA) supplementation can reduce the development of DN.
    Objectives: We performed a systematic review and meta-analysis to examine the effects of ALA supplementation on biological indices (albumin, creatinine, etc.) indicative of human DN.
    Methods: The search procedure included PubMed Central, Embase, Cochrane Library (trials), and Web of Science (protocol registration: INPLASY202060095).
    Results: We found that ALA supplementation decreased 24h urine albumin excretion rate in patients with diabetes (standardized mean difference=-2.27; confidence interval (CI)=(-4.09)-(-0.45); I
    Conclusion: The available evidence suggests that ALA supplementation does not improve biological indices that reflect DN in humans. Overall, we identified limited evidence, and therefore, the outcomes should be considered with caution.
    MeSH term(s) Albumins/therapeutic use ; Animals ; Creatinine ; Diabetes Mellitus/drug therapy ; Diabetic Nephropathies/drug therapy ; Dietary Supplements ; Female ; Humans ; Male ; Thioctic Acid/therapeutic use
    Chemical Substances Albumins ; Thioctic Acid (73Y7P0K73Y) ; Creatinine (AYI8EX34EU)
    Language English
    Publishing date 2021-09-08
    Publishing country United Arab Emirates
    Document type Systematic Review
    ISSN 1875-6417
    ISSN (online) 1875-6417
    DOI 10.2174/1573399817666210914103329
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  8. Article ; Online: App-Mohedo®: A mobile app for the management of chronic pelvic pain. A design and development study.

    Díaz-Mohedo, Esther / Carrillo-León, Antonio L / Calvache-Mateo, Andrés / Ptak, Magdalena / Romero-Franco, Natalia / Carlos-Fernández, Juan

    International journal of medical informatics

    2024  Volume 186, Page(s) 105410

    Abstract: Background: Chronic Pelvic Pain (CPP) has been described as a public health priority worldwide, and it is among the most prevalent and costly healthcare problems. Graded motor imagery (GMI) is a therapeutic tool that has been successfully used to ... ...

    Abstract Background: Chronic Pelvic Pain (CPP) has been described as a public health priority worldwide, and it is among the most prevalent and costly healthcare problems. Graded motor imagery (GMI) is a therapeutic tool that has been successfully used to improve pain in several chronic conditions. GMI therapy is divided into three stages: laterality training (LRJT, Left Right Judgement Task), imagined movements, and mirror therapy. No tool that allows working with LRJT in pelvic floor has been developed to date.
    Objective: This research aims to describe the process followed for the development of a highly usable, multi-language and multi-platform mobile application using GMI with LRJT to improve the treatment of patients with CPP. In addition, this will require achieving two other goals: firstly, to generate 550 pelvic floor images and, subsequently, to carry out an empirical study to objectively classify them into different difficulty levels of. This will allow the app to properly organize and plan the different therapy sessions to be followed by each patient.
    Methodology: For the design, evaluation and development of the app, an open methodology of user-centered design (MPIu + a) was applied. Furthermore, to classify and establish the pelvic floor images of the app in different difficulty levels, an observational, cross-sectional study was conducted with 132 volunteers through non-probabilistic sampling.
    Results: On one hand, applying MPIu+a, a total of 5 phases were required to generate an easy-to-use mobile application. On the other hand, the 550 pelvic floor images were classified into 3 difficulty levels (based on the percentage of correct answers and response time used by the participants in the classification process of each image): Level 1 (191 images with Accuracy = 100 % and RT = [0-2.5] seconds); Level 2 (208 images with Accuracy = 75-100 % and RT = [2.5-5] seconds); and Level 3 (151 images with Accuracy = 50-75 % and RT > 5 s).
    Conclusion: App-Mohedo® is the first multi-platform, multi-language and easy-to-use mobile application that, through GMI with LRJT, and with an adequate bank of images classified into three levels of difficulty, can be used as a complementary therapeutic tool in the treatment of patients with CPP. This work can also serve as an example, model or guide when applying a user-centered methodology, as MPIu + a, to the development of other apps, especially in the field of health.
    MeSH term(s) Humans ; Mobile Applications ; Cross-Sectional Studies ; Functional Laterality/physiology ; Chronic Disease ; Pelvic Pain/therapy
    Language English
    Publishing date 2024-03-15
    Publishing country Ireland
    Document type Journal Article
    ZDB-ID 1466296-6
    ISSN 1872-8243 ; 1386-5056
    ISSN (online) 1872-8243
    ISSN 1386-5056
    DOI 10.1016/j.ijmedinf.2024.105410
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  9. Article: Effects of Low Dose Caffeine on Post-Exercise Heart Rate Variability: A Double-Blind Placebo-Controlled Trial.

    Sargent, Cagney T / Shahbal, Tareq K / Carrillo, Andres E / Amorim, Tania / Edsall, Jason R / Ryan, Emily J / Ryan, Edward J

    International journal of exercise science

    2021  Volume 15, Issue 2, Page(s) 103–112

    Abstract: Caffeine may impact post-exercise heart rate variability (HRV); although, studies have yielded inconsistent findings. We examined the effects of low dose caffeine on post-exercise HRV. Healthy, college-aged adults [ ...

    Abstract Caffeine may impact post-exercise heart rate variability (HRV); although, studies have yielded inconsistent findings. We examined the effects of low dose caffeine on post-exercise HRV. Healthy, college-aged adults [
    Language English
    Publishing date 2021-12-01
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2411342-6
    ISSN 1939-795X
    ISSN 1939-795X
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  10. Article ; Online: Complex Mitral Paravalvular Leak Closure: 3D Printing to the Rescue.

    Andrés-Cordón, Joan F / Vilalta, Victoria / Millán, Xavier / Moustafa, Abdel H / Fernández-Nofrerias, Eduard / Julià, Ignasi / Carrillo, Xavier / Delgado, Victoria

    JACC. Cardiovascular interventions

    2023  Volume 16, Issue 17, Page(s) 2181–2182

    MeSH term(s) Humans ; Treatment Outcome ; Mitral Valve/diagnostic imaging ; Mitral Valve/surgery ; Mitral Valve Insufficiency/diagnostic imaging ; Mitral Valve Insufficiency/etiology ; Mitral Valve Insufficiency/surgery ; Heart Valve Prosthesis Implantation/adverse effects ; Printing, Three-Dimensional ; Cardiac Catheterization/adverse effects ; Heart Valve Prosthesis ; Prosthesis Failure ; Echocardiography, Transesophageal
    Language English
    Publishing date 2023-06-21
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2452157-7
    ISSN 1876-7605 ; 1936-8798
    ISSN (online) 1876-7605
    ISSN 1936-8798
    DOI 10.1016/j.jcin.2023.05.027
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6669: Show issues Location:
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