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  1. Article ; Online: Recent Improvements in Data From the Gun Violence Archive-Will They Lead to Change?

    Worsham, Christopher M / Jena, Anupam B

    JAMA network open

    2023  Volume 6, Issue 6, Page(s) e2316512

    MeSH term(s) Humans ; Gun Violence/prevention & control ; Violence/prevention & control ; Firearms
    Language English
    Publishing date 2023-06-01
    Publishing country United States
    Document type Journal Article ; Comment
    ISSN 2574-3805
    ISSN (online) 2574-3805
    DOI 10.1001/jamanetworkopen.2023.16512
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  2. Article ; Online: Optimal timing of influenza vaccination in young children: population based cohort study.

    Worsham, Christopher M / Bray, Charles F / Jena, Anupam B

    BMJ (Clinical research ed.)

    2024  Volume 384, Page(s) e077076

    Abstract: Objective: To assess optimal timing of influenza vaccination in young children.: Design: Population based cohort study.: Setting: United States.: Participants: Commercially insured children aged 2-5 years who were vaccinated against influenza ... ...

    Abstract Objective: To assess optimal timing of influenza vaccination in young children.
    Design: Population based cohort study.
    Setting: United States.
    Participants: Commercially insured children aged 2-5 years who were vaccinated against influenza during 2011-18.
    Main outcome measure: Rates of diagnosis of influenza among children who were vaccinated against influenza, by birth month.
    Results: Overall, 819 223 children aged 2-5 received influenza vaccination. Children vaccinated in November and December were least likely to have a diagnosis of influenza, a finding that may be confounded by unmeasured factors that influence the timing of vaccination and risk of influenza. Vaccination commonly occurred on days of preventive care visits and during birth months. Children born in October were disproportionately vaccinated in October and were, on average, vaccinated later than children born in August and earlier than those born in December. Children born in October had the lowest rate of influenza diagnosis (for example, 2.7% (6016/224 540) versus 3.0% (6462/212 622) for those born in August; adjusted odds ratio 0.88, 95% confidence interval 0.85 to 0.92).
    Conclusions: In a quasi-experimental analysis of young children vaccinated against influenza, birth month was associated with the timing of vaccination through its influence on the timing of preventive care visits. Children born in October were most likely to be vaccinated in October and least likely to have a diagnosis of influenza, consistent with recommendations promoting October vaccination.
    MeSH term(s) Child ; Female ; Pregnancy ; Humans ; United States/epidemiology ; Child, Preschool ; Cohort Studies ; Influenza, Human/epidemiology ; Influenza, Human/prevention & control ; Parturition ; Vaccination ; Odds Ratio ; Influenza Vaccines/therapeutic use
    Chemical Substances Influenza Vaccines
    Language English
    Publishing date 2024-02-21
    Publishing country England
    Document type Journal Article
    ZDB-ID 1362901-3
    ISSN 1756-1833 ; 0959-8154 ; 0959-8146 ; 0959-8138 ; 0959-535X ; 1759-2151
    ISSN (online) 1756-1833
    ISSN 0959-8154 ; 0959-8146 ; 0959-8138 ; 0959-535X ; 1759-2151
    DOI 10.1136/bmj-2023-077076
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  3. Article ; Online: The Role of the Household in Prescription Opioid Safety.

    Worsham, Christopher M / Barnett, Michael L

    JAMA network open

    2020  Volume 3, Issue 3, Page(s) e201108

    MeSH term(s) Adolescent ; Analgesics, Opioid ; Drug Prescriptions ; Family ; Humans ; Substance-Related Disorders ; Young Adult
    Chemical Substances Analgesics, Opioid
    Language English
    Publishing date 2020-03-02
    Publishing country United States
    Document type Journal Article ; Comment
    ISSN 2574-3805
    ISSN (online) 2574-3805
    DOI 10.1001/jamanetworkopen.2020.1108
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  4. Article ; Online: Association between UFO sightings and emergency department visits.

    Worsham, Christopher M / Zimerman, André / Woo, Jaemin / Shaw, David / Jena, Anupam B

    The American journal of emergency medicine

    2023  Volume 66, Page(s) 164–166

    MeSH term(s) Humans ; Emergency Service, Hospital
    Language English
    Publishing date 2023-01-15
    Publishing country United States
    Document type Letter
    ZDB-ID 605890-5
    ISSN 1532-8171 ; 0735-6757
    ISSN (online) 1532-8171
    ISSN 0735-6757
    DOI 10.1016/j.ajem.2023.01.022
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  5. Article ; Online: Analysis of institutional conflict of interest and bias in research findings and reporting.

    Varady, Nathan H / Worsham, Christopher M / Jena, Anupam B

    Healthcare (Amsterdam, Netherlands)

    2021  Volume 9, Issue 1, Page(s) 100515

    MeSH term(s) Conflict of Interest ; Humans
    Language English
    Publishing date 2021-01-28
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2724773-9
    ISSN 2213-0772 ; 2213-0764 ; 2213-0772
    ISSN (online) 2213-0772 ; 2213-0764
    ISSN 2213-0772
    DOI 10.1016/j.hjdsi.2020.100515
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  6. Article ; Online: Characterization of Prescription Patterns and Estimated Costs for Use of Oxygen Concentrators for Home Oxygen Therapy in the US.

    Kahn, Peter A / Worsham, Christopher M / Berland, Gretchen

    JAMA network open

    2021  Volume 4, Issue 10, Page(s) e2129967

    MeSH term(s) Drug Prescriptions/statistics & numerical data ; Equipment and Supplies/economics ; Equipment and Supplies/statistics & numerical data ; Hawaii ; Humans ; Oxygen/administration & dosage ; Oxygen/therapeutic use ; Oxygen Inhalation Therapy/economics ; Oxygen Inhalation Therapy/instrumentation ; Oxygen Inhalation Therapy/statistics & numerical data
    Chemical Substances Oxygen (S88TT14065)
    Language English
    Publishing date 2021-10-01
    Publishing country United States
    Document type Journal Article
    ISSN 2574-3805
    ISSN (online) 2574-3805
    DOI 10.1001/jamanetworkopen.2021.29967
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  7. Article ; Online: Changes in Minoxidil Prescribing After Media Attention About Oral Use for Hair Loss.

    Goodwin Cartwright, Brianna M / Wang, Michael / Rodriguez, Patricia / Stewart, Sarah / Worsham, Christopher M / Stucky, Nick / Jena, Anupam B

    JAMA network open

    2023  Volume 6, Issue 5, Page(s) e2312477

    MeSH term(s) Humans ; Minoxidil/therapeutic use ; Alopecia/drug therapy ; Administration, Oral
    Chemical Substances Minoxidil (5965120SH1)
    Language English
    Publishing date 2023-05-01
    Publishing country United States
    Document type Letter
    ISSN 2574-3805
    ISSN (online) 2574-3805
    DOI 10.1001/jamanetworkopen.2023.12477
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  8. Article ; Online: Air Hunger and Psychological Trauma in Ventilated Patients with COVID-19. An Urgent Problem.

    Worsham, Christopher M / Banzett, Robert B / Schwartzstein, Richard M

    Annals of the American Thoracic Society

    2020  Volume 17, Issue 8, Page(s) 926–927

    MeSH term(s) Betacoronavirus/isolation & purification ; COVID-19 ; Coronavirus Infections/epidemiology ; Coronavirus Infections/physiopathology ; Coronavirus Infections/therapy ; Dyspnea/etiology ; Dyspnea/physiopathology ; Dyspnea/psychology ; Humans ; Narcotics/pharmacology ; Opiate Alkaloids/pharmacology ; Pandemics ; Pneumonia, Viral/epidemiology ; Pneumonia, Viral/physiopathology ; Pneumonia, Viral/therapy ; Psychological Trauma/etiology ; Psychological Trauma/physiopathology ; Respiration, Artificial/adverse effects ; Respiration, Artificial/methods ; Respiration, Artificial/psychology ; Respiratory Insufficiency/etiology ; Respiratory Insufficiency/psychology ; SARS-CoV-2 ; Treatment Outcome
    Chemical Substances Narcotics ; Opiate Alkaloids
    Keywords covid19
    Language English
    Publishing date 2020-06-04
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2717461-X
    ISSN 2325-6621 ; 1943-5665 ; 2325-6621
    ISSN (online) 2325-6621 ; 1943-5665
    ISSN 2325-6621
    DOI 10.1513/AnnalsATS.202004-322VP
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    Zs.A 5828: Show issues Location:
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  9. Article ; Online: Carbon Monoxide Poisoning during Major U.S. Power Outages.

    Worsham, Christopher M / Woo, Jaemin / Kearney, Michael J / Bray, Charles F / Jena, Anupam B

    The New England journal of medicine

    2022  Volume 386, Issue 2, Page(s) 191–192

    MeSH term(s) Air Pollution, Indoor ; Carbon Monoxide Poisoning/epidemiology ; Electric Power Supplies ; Emergency Service, Hospital/statistics & numerical data ; Humans ; Natural Disasters ; United States/epidemiology
    Language English
    Publishing date 2022-01-24
    Publishing country United States
    Document type Letter
    ZDB-ID 207154-x
    ISSN 1533-4406 ; 0028-4793
    ISSN (online) 1533-4406
    ISSN 0028-4793
    DOI 10.1056/NEJMc2113554
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  10. Article ; Online: Dyspnea, Acute Respiratory Failure, Psychological Trauma, and Post-ICU Mental Health: A Caution and a Call for Research.

    Worsham, Christopher M / Banzett, Robert B / Schwartzstein, Richard M

    Chest

    2020  Volume 159, Issue 2, Page(s) 749–756

    Abstract: Dyspnea is an uncomfortable sensation with the potential to cause psychological trauma. Patients presenting with acute respiratory failure, particularly when tidal volume is restricted during mechanical ventilation, may experience the most distressing ... ...

    Abstract Dyspnea is an uncomfortable sensation with the potential to cause psychological trauma. Patients presenting with acute respiratory failure, particularly when tidal volume is restricted during mechanical ventilation, may experience the most distressing form of dyspnea known as air hunger. Air hunger activates brain pathways known to be involved in posttraumatic stress disorder (PTSD), anxiety, and depression. These conditions are considered part of the post-intensive care syndrome. These sequelae may be even more prevalent among patients with ARDS. Low tidal volume, a mainstay of modern therapy for ARDS, is difficult to avoid and is likely to cause air hunger despite sedation. Adjunctive neuromuscular blockade does not prevent or relieve air hunger, but it does prevent the patient from communicating discomfort to caregivers. Consequently, paralysis may also contribute to the development of PTSD. Although research has identified post-ARDS PTSD as a cause for concern, and investigators have taken steps to quantify the burden of disease, there is little information to guide mechanical ventilation strategies designed to reduce its occurrence. We suggest such efforts will be more successful if they are directed at the known mechanisms of air hunger. Investigation of the antidyspnea effects of sedative and analgesic drugs commonly used in the ICU and their impact on post-ARDS PTSD symptoms is a logical next step. Although in practice we often accept negative consequences of life-saving therapies as unavoidable, we must understand the negative sequelae of our therapies and work to minimize them under our primary directive to "first, do no harm" to patients.
    MeSH term(s) Anxiety/psychology ; Critical Illness/psychology ; Depression/psychology ; Dyspnea/psychology ; Female ; Humans ; Intensive Care Units ; Male ; Respiration, Artificial/adverse effects ; Respiration, Artificial/psychology ; Respiratory Distress Syndrome/psychology ; Respiratory Distress Syndrome/therapy ; Risk Factors ; Stress Disorders, Post-Traumatic/psychology ; Tidal Volume
    Keywords covid19
    Language English
    Publishing date 2020-10-01
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Review
    ZDB-ID 1032552-9
    ISSN 1931-3543 ; 0012-3692
    ISSN (online) 1931-3543
    ISSN 0012-3692
    DOI 10.1016/j.chest.2020.09.251
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