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  1. Article ; Online: Air pollution and SARS-CoV-2 in the Po Valley: possible environmental persistence?

    Di Cerbo, Alessandro

    Minerva medica

    2020  Volume 111, Issue 4, Page(s) 306–307

    MeSH term(s) Air Pollution/adverse effects ; Betacoronavirus/physiology ; COVID-19 ; Copper ; Coronavirus Infections/epidemiology ; Coronavirus Infections/transmission ; Coronavirus Infections/virology ; Humans ; Iron ; Italy/epidemiology ; Pandemics ; Particle Size ; Particulate Matter/toxicity ; Pneumonia, Viral/epidemiology ; Pneumonia, Viral/transmission ; Pneumonia, Viral/virology ; SARS-CoV-2 ; Virus Replication
    Chemical Substances Particulate Matter ; Copper (789U1901C5) ; Iron (E1UOL152H7)
    Keywords covid19
    Language English
    Publishing date 2020-04-23
    Publishing country Italy
    Document type Editorial
    ZDB-ID 123586-2
    ISSN 1827-1669 ; 0026-4806
    ISSN (online) 1827-1669
    ISSN 0026-4806
    DOI 10.23736/S0026-4806.20.06586-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

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  2. Article: Cell-Free Supernatant from a Strain of

    Pedretti, Natalia / Iseppi, Ramona / Condò, Carla / Spaggiari, Luca / Messi, Patrizia / Pericolini, Eva / Di Cerbo, Alessandro / Ardizzoni, Andrea / Sabia, Carla

    Microorganisms

    2024  Volume 12, Issue 4

    Abstract: In recent years, the search for new compounds with antibacterial activity has drastically increased due to the spread of antibiotic-resistant microorganisms. In this study, we analyzed Cell-Free Supernatant (CFS) ... ...

    Abstract In recent years, the search for new compounds with antibacterial activity has drastically increased due to the spread of antibiotic-resistant microorganisms. In this study, we analyzed Cell-Free Supernatant (CFS) from
    Language English
    Publishing date 2024-04-02
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2720891-6
    ISSN 2076-2607
    ISSN 2076-2607
    DOI 10.3390/microorganisms12040718
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  4. Article: Formulation and Preparation of Losartan-Potassium-Loaded Controlled-Release Matrices Using Ethocel Grade 10 to Establish a Correlation between In Vitro and In Vivo Results.

    Khan, Kamran Ahmad / Ahmad, Ashfaq / Marini, Carlotta / Nicotra, Mario / Di Cerbo, Alessandro / Fazal-Ur-Rehman / Ullah, Naveed / Khan, Gul Majid

    Pharmaceutics

    2024  Volume 16, Issue 2

    Abstract: In the current study, matrices of losartan potassium were formulated with two different polymers (Ethocel 10 premium and Ethocel 10FP premium), along with a filler and a lubricant, at different drug-to- ... ...

    Abstract In the current study, matrices of losartan potassium were formulated with two different polymers (Ethocel 10 premium and Ethocel 10FP premium), along with a filler and a lubricant, at different drug-to-polymer
    Language English
    Publishing date 2024-01-28
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2527217-2
    ISSN 1999-4923
    ISSN 1999-4923
    DOI 10.3390/pharmaceutics16020186
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  5. Article: Comparison between an Emerging Point-of-Care Tool for TSH Evaluation and a Centralized Laboratory-Based Method in a Cohort of Patients from Southern Italy.

    Di Cerbo, Alfredo / Quagliano, Nazario / Napolitano, Antonella / Pezzuto, Federica / Iannitti, Tommaso / Di Cerbo, Alessandro

    Diagnostics (Basel, Switzerland)

    2021  Volume 11, Issue 9

    Abstract: Endocrine and metabolic disorders are a common condition in Europe and worldwide, and, among these, thyroid dysfunction still remains a problem. The measurement of thyroid stimulating hormone (TSH) levels represents the first-line assay for the ... ...

    Abstract Endocrine and metabolic disorders are a common condition in Europe and worldwide, and, among these, thyroid dysfunction still remains a problem. The measurement of thyroid stimulating hormone (TSH) levels represents the first-line assay for the assessment of thyroid function. In the present study, we compared serum concentrations of TSH, measured using a commercially available point-of-care test (POCT) method (FastPack
    Language English
    Publishing date 2021-08-31
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662336-5
    ISSN 2075-4418
    ISSN 2075-4418
    DOI 10.3390/diagnostics11091590
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  6. Article ; Online: Ameliorative effects of Dunaliella salina microalgae on nanoparticle (ZnO NPs)-induced toxicity in fish.

    Farag, Mayada R / Alagawany, Mahmoud / Alsulami, Lafi S / Di Cerbo, Alessandro / Attia, Youssef

    Environmental science and pollution research international

    2023  Volume 30, Issue 58, Page(s) 121915–121928

    Abstract: Dunaliella salina (D. salina) is a well-known microalga that contains considerable amounts of nutritious and medicinal bioactive components. This work studied the modulatory role of D. salina against zinc oxide nanoparticle (ZnO NPs)-induced neurotoxic ... ...

    Abstract Dunaliella salina (D. salina) is a well-known microalga that contains considerable amounts of nutritious and medicinal bioactive components. This work studied the modulatory role of D. salina against zinc oxide nanoparticle (ZnO NPs)-induced neurotoxic effects in adult zebrafish. Fishes were subjected to 0.69 mg L
    MeSH term(s) Animals ; Zinc Oxide/toxicity ; Microalgae/metabolism ; Zebrafish/metabolism ; Acetylcholinesterase/metabolism ; Hydrogen Peroxide/pharmacology ; Nanoparticles/toxicity ; Antioxidants/metabolism ; Oxidative Stress
    Chemical Substances Zinc Oxide (SOI2LOH54Z) ; Acetylcholinesterase (EC 3.1.1.7) ; Hydrogen Peroxide (BBX060AN9V) ; Antioxidants
    Language English
    Publishing date 2023-11-14
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1178791-0
    ISSN 1614-7499 ; 0944-1344
    ISSN (online) 1614-7499
    ISSN 0944-1344
    DOI 10.1007/s11356-023-30933-7
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    In stock of ZB MED Bonn / Germany

    Z 5915: Show issues

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  7. Article ; Online: Characterization of virulence factors and antimicrobial resistance in Staphylococcus spp. isolated from clinical samples.

    Pedretti, Natalia / Iseppi, Ramona / Condò, Carla / Ghazanfar, Shakira / Messi, Patrizia / Di Cerbo, Alessandro / Sabia, Carla

    Folia microbiologica

    2024  

    Abstract: The virulence factors, antibiotic resistance patterns, and the associated genetic elements have been investigated in Staphylococcus species. A total of 100 strains has been isolated from clinical samples in the Microbiology Laboratory of Hesperia ... ...

    Abstract The virulence factors, antibiotic resistance patterns, and the associated genetic elements have been investigated in Staphylococcus species. A total of 100 strains has been isolated from clinical samples in the Microbiology Laboratory of Hesperia Hospital, Modena, Italy, and identified as Staphylococcus aureus (65), Staphylococcus epidermidis (24), Staphylococcus hominis (3), Staphylococcus saprophyticus (3), and Staphylococcus warneri (5). All the strains were analyzed to determine phenotypic and genotypic characters, notably the virulence factors, the antibiotics susceptibility, and the genetic determinants. The highest percentage of resistance in Staphylococcus spp. was found for erythromycin and benzylpenicillin (87% and 85%, respectively). All S. aureus, two S. epidermidis (8.3%), and one S. saprophyticus (33.3%) strains were resistant to oxacillin. The methicillin resistance gene (mecA) was detected by polymerase chain reaction (PCR) amplification in 65 S. aureus strains and in 3 coagulase-negative staphylococci (CoNS) (8.6%). With regard to the virulence characteristics, all the S. aureus were positive to all virulence tests, except for slime test. Among the CoNS isolates, 19 (79.1%) S. epidermidis and one (33.3%) S. saprophyticus strains resulted positive for the slime test only. The results obtained are useful for a more in-depth understanding of the function and contribution of S. aureus and CoNS antibiotic resistance and virulence factors to staphylococcal infections. In particular, the production of slime is very important for CoNS, a virulence factor frequently found in infections caused by these strains. Further investigations on the genetic relatedness among strains of different sources will be useful for epidemiological and monitoring purposes and will enable us to develop new strategies to counteract the diffusion of methicillin-resistant S. aureus (MRSA) and CoNS strains not only in clinical field, but also in other related environments.
    Language English
    Publishing date 2024-02-17
    Publishing country United States
    Document type Journal Article
    ZDB-ID 240503-9
    ISSN 1874-9356 ; 0015-5632
    ISSN (online) 1874-9356
    ISSN 0015-5632
    DOI 10.1007/s12223-024-01148-1
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 845: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  8. Article ; Online: Evidence for Endogenous Opioid Dependence Related to Latent Sensitization in a Rat Model of Chronic Inflammatory Pain.

    Morales-Medina, Julio César / Pugliese, Nicola / Di Cerbo, Alessandro / Zizzadoro, Claudia / Iannitti, Tommaso

    International journal of molecular sciences

    2023  Volume 24, Issue 3

    Abstract: Studies performed in a mouse model of chronic inflammatory pain induced by intraplantar injection of complete Freund's adjuvant (CFA) have shown that constitutive activation of the endogenous opioid signaling, besides serving as a mechanism of endogenous ...

    Abstract Studies performed in a mouse model of chronic inflammatory pain induced by intraplantar injection of complete Freund's adjuvant (CFA) have shown that constitutive activation of the endogenous opioid signaling, besides serving as a mechanism of endogenous analgesia that tonically represses pain sensitization, also generates a state of endogenous opioid dependence. Since species-related differences concerning pain biology and addictive behaviors occur between mice and rats, the present study explored whether the coexistence of endogenous opioid analgesia and endogenous opioid dependence also characterizes a homologous rat model. To this aim, CFA-injured Wistar rats were treated with either 3 mg/kg or 10 mg/kg of the opioid receptor inverse agonist naltrexone (NTX) during the pain remission phase and monitored for 60 min for possible withdrawal behaviors. At 3 mg/kg, NTX, besides inducing the reinstatement of mechanical allodynia, also caused a distinct appearance of ptosis, with slight but nonsignificant changes to the occurrence of teeth chatters and rearing. On the other hand, 10 mg/kg of NTX failed to unmask pain sensitization and induced significantly lower levels of ptosis than 3 mg/kg. Such an NTX-related response pattern observed in the rat CFA model seems to differ substantially from the pattern previously described in the mouse CFA model. This supports the knowledge that mice and rats are not identical in terms of pharmacological response and stresses the importance of choosing the appropriate species for preclinical pain research purposes depending on the scientific question being asked.
    MeSH term(s) Rats ; Mice ; Animals ; Analgesics, Opioid/pharmacology ; Drug Inverse Agonism ; Rats, Wistar ; Inflammation/drug therapy ; Chronic Pain/drug therapy ; Hyperalgesia/drug therapy ; Opioid Peptides/therapeutic use ; Naltrexone/pharmacology ; Naltrexone/therapeutic use ; Opioid-Related Disorders/drug therapy ; Disease Models, Animal
    Chemical Substances Analgesics, Opioid ; Opioid Peptides ; Naltrexone (5S6W795CQM)
    Language English
    Publishing date 2023-02-01
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms24032812
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  9. Article: Understanding the Pathogenesis of Red Mark Syndrome in Rainbow Trout (

    Galeotti, Marco / Orioles, Massimo / Saccà, Elena / Byadgi, Omkar / Pesaro, Stefano / Di Cerbo, Alessandro / Magi, Gian Enrico

    Animals : an open access journal from MDPI

    2023  Volume 13, Issue 6

    Abstract: Red mark syndrome (RMS) is a widespread skin disorder of rainbow trout in freshwater aquaculture, believed to be caused by ... ...

    Abstract Red mark syndrome (RMS) is a widespread skin disorder of rainbow trout in freshwater aquaculture, believed to be caused by a
    Language English
    Publishing date 2023-03-20
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2606558-7
    ISSN 2076-2615
    ISSN 2076-2615
    DOI 10.3390/ani13061103
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  10. Article ; Online: Heat detoxification of Jatropha cucas meal and its effect on productive and reproductive performance of quail.

    Attia, Youssef A / Farag, Mayada R / Al-Harthi, Mohammed A / Bovera, Fulvia / Alqurashi, Adel D / Di Cerbo, Alessandro / Alagawany, Mahmoud

    Poultry science

    2023  Volume 102, Issue 12, Page(s) 103072

    Abstract: Jatropha is a large, multipurpose, drought-tolerant plant with many traits and great potential as a biofuel crop. It originates from Central America but is now distributed throughout the tropics, including Africa and Asia. The study determines whether ... ...

    Abstract Jatropha is a large, multipurpose, drought-tolerant plant with many traits and great potential as a biofuel crop. It originates from Central America but is now distributed throughout the tropics, including Africa and Asia. The study determines whether the dietary inclusion of raw Jatropha cucas meal (RJM, 3.5%) had negative impacts on the reproductive and productive performances of male Japanese quail as well as whether these impacts could be mitigated by heating the jatropha meal at 100°C for 24 or 48 h (JH
    MeSH term(s) Animals ; Quail ; Coturnix ; Jatropha ; Hot Temperature ; Chickens ; Diet/veterinary ; Antioxidants ; Animal Feed/analysis
    Chemical Substances Antioxidants
    Language English
    Publishing date 2023-09-01
    Publishing country England
    Document type Journal Article
    ZDB-ID 242586-5
    ISSN 1525-3171 ; 0032-5791
    ISSN (online) 1525-3171
    ISSN 0032-5791
    DOI 10.1016/j.psj.2023.103072
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    In stock of ZB MED Cologne/Königswinter

    Zs.B 853: Show issues Location:
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