LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 96

Search options

  1. Article ; Online: Air Disinfection for Airborne Infection Control with a Focus on COVID-19: Why Germicidal UV is Essential

    Nardell, Edward A

    Photochemistry and photobiology

    2021  Volume 97, Issue 3, Page(s) 493–497

    Abstract: Aerosol transmission is now widely accepted as the principal way that COVID-19 is spread, as has the importance of ventilation-natural and mechanical. But in other than healthcare facilities, mechanical ventilation is designed for comfort, not airborne ... ...

    Abstract Aerosol transmission is now widely accepted as the principal way that COVID-19 is spread, as has the importance of ventilation-natural and mechanical. But in other than healthcare facilities, mechanical ventilation is designed for comfort, not airborne infection control, and cannot achieve the 6 to 12 room air changes per hour recommended for airborne infection control. More efficient air filters have been recommended in ventilation ducts despite a lack of convincing evidence that SARS-CoV-2 virus spreads through ventilation systems. Most transmission appears to occur in rooms where both an infectious source COVID-19 case and other susceptible occupants share the same air. Only two established room-based technologies are available to supplement mechanical ventilation: portable room air cleaners and upper room germicidal UV air disinfection. Portable room air cleaners can be effective, but performance is limited by their clean air delivery rate relative to room volume. SARS-CoV-2 is highly susceptible to GUV, an 80-year-old technology that has been shown to safely, quietly, effectively and economically produce the equivalent of 10 to 20 or more air changes per hour under real life conditions. For these reasons, upper room GUV is the essential engineering intervention for reducing COVID-19 spread.
    MeSH term(s) Air Microbiology ; COVID-19/prevention & control ; Disinfection/instrumentation ; Disinfection/methods ; Humans ; SARS-CoV-2/radiation effects ; Ultraviolet Rays ; Virus Inactivation/radiation effects
    Language English
    Publishing date 2021-04-05
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 123540-0
    ISSN 1751-1097 ; 0031-8655
    ISSN (online) 1751-1097
    ISSN 0031-8655
    DOI 10.1111/php.13421
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  2. Article ; Online: Time to Revise Our Tuberculosis Infection-Latency-Disease Model in High-burden Settings.

    Nardell, Edward A

    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

    2020  Volume 72, Issue 11, Page(s) 2016–2017

    MeSH term(s) Humans ; Latent Tuberculosis ; Tuberculosis
    Language English
    Publishing date 2020-06-25
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 1099781-7
    ISSN 1537-6591 ; 1058-4838
    ISSN (online) 1537-6591
    ISSN 1058-4838
    DOI 10.1093/cid/ciaa866
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  3. Article ; Online: Preventing Transmission of Mycobacterium Tuberculosis-A Refocused Approach.

    Nardell, Edward A

    Clinics in chest medicine

    2019  Volume 40, Issue 4, Page(s) 857–869

    Abstract: Traditional tuberculosis (TB) infection control focuses on the known patient with TB, usually on appropriate treatment. A refocused, intensified TB infection control approach is presented. Combined with active case finding and rapid molecular diagnostics, ...

    Abstract Traditional tuberculosis (TB) infection control focuses on the known patient with TB, usually on appropriate treatment. A refocused, intensified TB infection control approach is presented. Combined with active case finding and rapid molecular diagnostics, an approach called FAST is described as a convenient way to call attention to the untreated patient. Natural ventilation is the mainstay of air disinfection in much of the world. Germicidal ultraviolet technology is the most sustainable approach to air disinfection under resource-limited conditions. Testing and treatment of latent TB infection works to prevent reactivation but requires greater risk targeting in both low- and high-risk settings.
    MeSH term(s) Humans ; Infection Control/methods ; Mycobacterium tuberculosis/pathogenicity ; Tuberculosis/prevention & control
    Language English
    Publishing date 2019-11-15
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, U.S. Gov't, P.H.S. ; Review
    ZDB-ID 447455-7
    ISSN 1557-8216 ; 0272-5231
    ISSN (online) 1557-8216
    ISSN 0272-5231
    DOI 10.1016/j.ccm.2019.07.010
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  4. Article ; Online: Reply by Bueno de Mesquita

    Bueno de Mesquita, P Jacob / Sokas, Rosemary K / Rice, Mary B / Nardell, Edward A

    Annals of the American Thoracic Society

    2024  Volume 21, Issue 4, Page(s) 680–681

    Language English
    Publishing date 2024-02-23
    Publishing country United States
    Document type Letter
    ZDB-ID 2717461-X
    ISSN 2325-6621 ; 1943-5665 ; 2325-6621
    ISSN (online) 2325-6621 ; 1943-5665
    ISSN 2325-6621
    DOI 10.1513/AnnalsATS.202401-035LE
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  5. Article ; Online: Airborne Spread of SARS-CoV-2 and a Potential Role for Air Disinfection.

    Nardell, Edward A / Nathavitharana, Ruvandhi R

    JAMA

    2020  Volume 324, Issue 2, Page(s) 141–142

    MeSH term(s) Aerosols ; Air Microbiology ; Betacoronavirus ; COVID-19 ; Coronavirus Infections/prevention & control ; Coronavirus Infections/transmission ; Disinfection ; Humans ; Pandemics/prevention & control ; Pneumonia, Viral/prevention & control ; Pneumonia, Viral/transmission ; SARS-CoV-2
    Chemical Substances Aerosols
    Keywords covid19
    Language English
    Publishing date 2020-01-07
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, U.S. Gov't, Non-P.H.S.
    ZDB-ID 2958-0
    ISSN 1538-3598 ; 0254-9077 ; 0002-9955 ; 0098-7484
    ISSN (online) 1538-3598
    ISSN 0254-9077 ; 0002-9955 ; 0098-7484
    DOI 10.1001/jama.2020.7603
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  6. Article ; Online: Far-UVC: Technology Update with an Untapped Potential to Mitigate Airborne Infections.

    Bueno de Mesquita, P Jacob / Sokas, Rosemary K / Rice, Mary B / Nardell, Edward A

    Annals of the American Thoracic Society

    2023  Volume 20, Issue 12, Page(s) 1700–1702

    Language English
    Publishing date 2023-09-05
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2717461-X
    ISSN 2325-6621 ; 1943-5665 ; 2325-6621
    ISSN (online) 2325-6621 ; 1943-5665
    ISSN 2325-6621
    DOI 10.1513/AnnalsATS.202305-460VP
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  7. Article ; Online: Transmission and Institutional Infection Control of Tuberculosis.

    Nardell, Edward A

    Cold Spring Harbor perspectives in medicine

    2015  Volume 6, Issue 2, Page(s) a018192

    Abstract: Tuberculosis (TB) transmission control in institutions is evolving with increased awareness of the rapid impact of treatment on transmission, the importance of the unsuspected, untreated case of transmission, and the advent of rapid molecular diagnostics. ...

    Abstract Tuberculosis (TB) transmission control in institutions is evolving with increased awareness of the rapid impact of treatment on transmission, the importance of the unsuspected, untreated case of transmission, and the advent of rapid molecular diagnostics. With active case finding based on cough surveillance and rapid drug susceptibility testing, in theory, it is possible to be reasonably sure that no patient enters a facility with undiagnosed TB or drug resistance. Droplet nuclei transmission of TB is reviewed with an emphasis on risk factors relevant to control. Among environmental controls, natural ventilation and upper-room ultraviolet germicidal ultraviolet air disinfection are the most cost-effective choices, although high-volume mechanical ventilation can also be used. Room air cleaners are generally not recommended. Maintenance is required for all engineering solutions. Finally, personal protection with fit-tested respirators is used in many situations where administrative and engineering methods cannot assure protection.
    MeSH term(s) Ambulatory Care ; Cross Infection/prevention & control ; Cross Infection/transmission ; Environment Design ; Health Personnel ; Hospitalization ; Humans ; Infection Control/methods ; Occupational Diseases/prevention & control ; Respiratory Protective Devices ; Risk Factors ; Tuberculosis/prevention & control ; Tuberculosis/transmission ; Ventilation/methods
    Language English
    Publishing date 2015-08-20
    Publishing country United States
    Document type Journal Article ; Review
    ISSN 2157-1422
    ISSN (online) 2157-1422
    DOI 10.1101/cshperspect.a018192
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  8. Article ; Online: Airborne Spread of SARS-CoV-2 and a Potential Role for Air Disinfection

    Nardell, Edward A. / Nathavitharana, Ruvandhi R.

    JAMA

    2020  Volume 324, Issue 2, Page(s) 141

    Keywords General Medicine ; covid19
    Language English
    Publisher American Medical Association (AMA)
    Publishing country us
    Document type Article ; Online
    ZDB-ID 2958-0
    ISSN 1538-3598 ; 0254-9077 ; 0002-9955 ; 0098-7484
    ISSN (online) 1538-3598
    ISSN 0254-9077 ; 0002-9955 ; 0098-7484
    DOI 10.1001/jama.2020.7603
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    More links

    Kategorien

  9. Article: Ceiling impact on air disinfection performance of Upper-Room Germicidal Ultraviolet (UR-GUV).

    Zhu, Shengwei / Lin, Tong / Wang, Lingzhe / Nardell, Edward A / Vincent, Richard L / Srebric, Jelena

    Building and environment

    2022  Volume 224, Page(s) 109530

    Abstract: This study used Computational Fluid Dynamics (CFD) to investigate air disinfection for SARS-CoV-2 by the Upper-Room Germicidal Ultraviolet (UR-GUV), with focus on ceiling impact. The study includes three indoor settings, i.e., low (airport bus), medium ( ... ...

    Abstract This study used Computational Fluid Dynamics (CFD) to investigate air disinfection for SARS-CoV-2 by the Upper-Room Germicidal Ultraviolet (UR-GUV), with focus on ceiling impact. The study includes three indoor settings, i.e., low (airport bus), medium (classroom) and high (rehearsal room) ceilings, which were ventilated with 100% clean air (CA case), 80% air-recirculation with a low filtration (LF case), and 80% air-recirculation with a high filtration (HF case). According to the results, using UR-GUV can offset the increased infection risk caused by air recirculation, with viral concentrations in near field (NF) and far field (FF) in the LF case similar to those in the CA case. In the CA case, fraction remaining (
    Language English
    Publishing date 2022-08-31
    Publishing country England
    Document type Journal Article
    ISSN 0360-1323
    ISSN 0360-1323
    DOI 10.1016/j.buildenv.2022.109530
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

To top