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Article ; Online: Assessment of Air Pollution around Durra Refinery (Baghdad) from Emission NO2 Gas at April Monthof Air Pollution around Durra Refinery (Baghdad) from Emission NO2 Gas at April Month

Abbas M. Anad / Ahmed F. Hassoon / Monim. H. Al- Jiboori

Baghdad Science Journal, Vol 19, Iss

2022 Volume 3

Abstract: Nitrogen dioxide NO2 is one of the most dangerous contaminant in the air, its toxic gas that cause disturbing respiratory effects, most of it emitted from industrial sources especially from the stack of power plants and oil refineries. In this study ... ...

Abstract	Nitrogen dioxide NO2 is one of the most dangerous contaminant in the air, its toxic gas that cause disturbing respiratory effects, most of it emitted from industrial sources especially from the stack of power plants and oil refineries. In this study Gaussian equations modelled by Matlab program to state the effect of pollutant NO2 gas on area around Durra refinery, this program also evaluate some elements such as wind and stability and its effect on stacks height. Data used in this study is the amount of fuel oil and fuel gas burn inside refinery at a year 2017. Hourly April month data chosen as a case study because it’s unsteady month. After evaluate emission rate of the all fuel and calculate exit velocity from stack (consider all refinery unit is a point), effective height resulted. Effective height is test with other atmospheric element and with stability, and there is direct relation with unstable turner classes. After Gaussian model implemented results show that most pollutant area from pollutant of NO2 is Al-Jadriyah and Al-Karada area, this area is about 3-5 kilometer from the refinery point. The wind direction domain is from the south to south-east, thus most flow is to north, north-west and the pollutant level of NO2 is over the national ambient air quality standard in this area.
Keywords	Science ; Q
Subject code	910
Language	Arabic
Publishing date	2022-06-01T00:00:00Z
Publisher	College of Science for Women, University of Baghdad
Document type	Article ; Online
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Article ; Online: Quercetin modulates expression of serum exosomal long noncoding RNA NEAT1 to regulate the miR-129-5p/BDNF axis and attenuate cognitive impairment in diabetic mice.

Wang, Hui / Jayasankar, Narayanan / Thamaraikani, Tamilanban / Viktor, Patrik / Mohany, Mohamed / Al-Rejaie, Salim S / Alammar, Hasan Khalid / Anad, Enaam / Alhili, Farah / Hussein, Sinan F / Amin, Ali H / Lakshmaiya, Natrayan / Ahsan, Muhammad / Bahrami, Abolfazl / Akhavan-Sigari, Reza

Life sciences

2024 Volume 340, Page(s) 122449

Abstract: Aims: Cognitive impairment poses a considerable health challenge in the context of type 2 diabetes mellitus (T2DM), emphasizing the need for effective interventions. This study delves into the therapeutic efficacy of quercetin, a natural flavonoid, in ... ...

Abstract	Aims: Cognitive impairment poses a considerable health challenge in the context of type 2 diabetes mellitus (T2DM), emphasizing the need for effective interventions. This study delves into the therapeutic efficacy of quercetin, a natural flavonoid, in mitigating cognitive impairment induced by T2DM in murine models. Materials and methods: Serum exosome samples were obtained from both T2DM-related and healthy mice for transcriptome sequencing, enabling the identification of differentially expressed mRNAs and long noncoding RNAs (lncRNAs). Subsequent experiments were conducted to ascertain the binding affinity between mmu-miR-129-5p, NEAT1 and BDNF. The structural characteristics and dimensions of isolated exosomes were scrutinized, and the expression levels of exosome-associated proteins were quantified. Primary mouse hippocampal neurons were cultured for in vitro validation, assessing the expression of pertinent genes as well as neuronal vitality, proliferation, and apoptosis capabilities. For in vivo validation, a T2DM mouse model was established, and quercetin treatment was administered. Changes in various parameters, cognitive ability, and the expression of insulin-related proteins, along with pivotal signaling pathways, were monitored. Key findings: Analysis of serum exosomes from T2DM mice revealed dysregulation of NEAT1, mmu-miR-129-5p, and BDNF. In vitro investigations demonstrated that NEAT1 upregulated BDNF expression by inhibiting mmu-miR-129-5p. Overexpression of mmu-miR-129-5p or silencing NEAT1 resulted in the downregulation of insulin-related protein expression, enhanced apoptosis, and suppressed neuronal proliferation. In vivo studies validated that quercetin treatment significantly ameliorated T2DM-related cognitive impairment in mice. Significance: These findings suggest that quercetin holds promise in inhibiting hippocampal neuron apoptosis and improving T2DM-related cognitive impairment by modulating the NEAT1/miR-129-5p/BDNF pathway within serum exosomes.
MeSH term(s)	Animals ; Mice ; RNA, Long Noncoding/genetics ; RNA, Long Noncoding/metabolism ; Quercetin/pharmacology ; Brain-Derived Neurotrophic Factor/genetics ; Diabetes Mellitus, Type 2/complications ; Diabetes Mellitus, Type 2/drug therapy ; Diabetes Mellitus, Type 2/genetics ; Diabetes Mellitus, Experimental/complications ; Cell Proliferation/genetics ; MicroRNAs/genetics ; MicroRNAs/metabolism ; Cognitive Dysfunction/drug therapy ; Cognitive Dysfunction/genetics ; Insulins
Chemical Substances	RNA, Long Noncoding ; Quercetin (9IKM0I5T1E) ; Brain-Derived Neurotrophic Factor ; MicroRNAs ; Insulins
Language	English
Publishing date	2024-01-20
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	3378-9
ISSN	1879-0631 ; 0024-3205
ISSN (online)	1879-0631
ISSN	0024-3205
DOI	10.1016/j.lfs.2024.122449
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Article: A simple method for selecting urine samples that need culturing.

Anad, F Y

Annals of Saudi medicine

2007 Volume 21, Issue 1-2, Page(s) 104–105

Language	English
Publishing date	2007-01-28
Publishing country	Saudi Arabia
Document type	Journal Article
ZDB-ID	639014-6
ISSN	0975-4466 ; 0256-4947
ISSN (online)	0975-4466
ISSN	0256-4947
DOI	10.5144/0256-4947.2001.104
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Article ; Online: Simulation Effect of Stability Classes on SO 2 Concentration in Daura Refinery and Neighboring Regions

abbas majeed anad / Monim H. Al-Jiboori / Ahmed F. Hassoon

Mustansiriyah Journal of Science, Vol 30, Iss 3, Pp 1-

2019 Volume 8

Abstract: ... that the in atmospheric stability class (F) concentrations of sulfur oxides is (54442mg/m 3 ) at distance 100m and (5127 ...

Abstract	Sulfur dioxide (SO 2 ) is one of the most dangerous pollutants in the air. Most of the gas is emitted from industrial sources, mainly steam power plants, which account for more than 50% of it. Its consider toxic gas that cause irritating respiratory effects in this study the effect of air pollution around Durra refinery and its neighborhood. Where adopted in the study. the data of gaseous pollutants in the air (sulfur dioxide) were analyzed in the area south of Baghdad at January month that is have high frequent of stability condition . The data provided by the Ministry of Oil / Baghdad for 2017. In addition, the effect of air stability classes on the quantities of this pollutant. The results of the study showed that the in atmospheric stability class (F) concentrations of sulfur oxides is (54442mg/m 3 ) at distance 100m and (5127 mg/m 3 ) at distance 10000m were the highest in the region. Overall results show that the concentration rates reached relatively high values during the stable and very stable atmospheric stability and that the values for the month of January for sulfur dioxide were found to be high and are inversely proportional to the speed of the wind.
Keywords	Effect of stability ; SO 2 concentration ; Gaussian Plume Model ; Science ; Q
Language	Arabic
Publishing date	2019-10-01T00:00:00Z
Publisher	Al-Mustansiriyah University
Document type	Article ; Online
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Article ; Online: A simple method for selecting urine samples that need culturing.

Anad F

Annals of Saudi Medicine, Vol 21, Iss -1, Pp 104-

2001 Volume 5

Keywords	Medicine (General) ; R5-920 ; Medicine ; R ; DOAJ:Medicine (General) ; DOAJ:Health Sciences
Language	English
Publishing date	2001-01-01T00:00:00Z
Publisher	King Faisal Specialist Hospital and Research Centre
Document type	Article ; Online
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Article ; Online: Identification of the A293 (AVE1231) Binding Site in the Cardiac Two-Pore-Domain Potassium Channel TASK-1: a Common Low Affinity Antiarrhythmic Drug Binding Site.

Wiedmann, Felix / Kiper, Aytug K / Bedoya, Mauricio / Ratte, Antonius / Rinné, Susanne / Kraft, Manuel / Waibel, Maximilian / Anad, Priya / Wenzel, Wolfgang / González, Wendy / Katus, Hugo A / Decher, Niels / Schmidt, Constanze

Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology

2019 Volume 52, Issue 5, Page(s) 1223–1235

Abstract: Background/aims: The two-pore-domain potassium channel TASK-1 regulates atrial action potential duration. Due to the atrium-specific expression of TASK-1 in the human heart and the functional upregulation of TASK-1 currents in atrial fibrillation (AF), ... ...

Abstract	Background/aims: The two-pore-domain potassium channel TASK-1 regulates atrial action potential duration. Due to the atrium-specific expression of TASK-1 in the human heart and the functional upregulation of TASK-1 currents in atrial fibrillation (AF), TASK-1 represents a promising target for the treatment of AF. Therefore, detailed knowledge of the molecular determinants of TASK-1 inhibition may help to identify new drugs for the future therapy of AF. In the current study, the molecular determinants of TASK-1 inhibition by the potent and antiarrhythmic compound A293 (AVE1231) were studied in detail. Methods: Alanine-scanning mutagenesis together with two-electrode voltage-clamp recordings were combined with in silico docking experiments. Results: Here, we have identified Q126 located in the M2 segment together with L239 and N240 of the M4 segment as amino acids essential for the A293-mediated inhibition of TASK-1. These data indicate a binding site which is different to that of A1899 for which also residues of the pore signature sequence and the late M4 segments are essential. Using in silico docking experiments, we propose a binding site at the lower end of the cytosolic pore, located at the entry to lateral side fenestrations of TASK-1. Strikingly, TASK-1 inhibition by the low affinity antiarrhythmic TASK-1 blockers propafenone, amiodarone and carvedilol was also strongly diminished by mutations at this novel binding site. Conclusion: We have identified the A293 binding site in the central cavity of TASK-1 and propose that this site might represent a conserved site of action for many low affinity antiarrhythmic TASK-1 blockers.
MeSH term(s)	Amino Acid Substitution ; Animals ; Anti-Arrhythmia Agents/chemistry ; Binding Sites ; Humans ; Mutagenesis, Site-Directed ; Mutation, Missense ; Nerve Tissue Proteins/antagonists & inhibitors ; Nerve Tissue Proteins/chemistry ; Nerve Tissue Proteins/genetics ; Nerve Tissue Proteins/metabolism ; Potassium Channels, Tandem Pore Domain/antagonists & inhibitors ; Potassium Channels, Tandem Pore Domain/chemistry ; Potassium Channels, Tandem Pore Domain/genetics ; Potassium Channels, Tandem Pore Domain/metabolism ; Xenopus laevis
Chemical Substances	Anti-Arrhythmia Agents ; Nerve Tissue Proteins ; Potassium Channels, Tandem Pore Domain ; potassium channel subfamily K member 3 (1HQ3YCN4GS)
Language	English
Publishing date	2019-04-18
Publishing country	Germany
Document type	Journal Article
ZDB-ID	1067572-3
ISSN	1421-9778 ; 1015-8987
ISSN (online)	1421-9778
ISSN	1015-8987
DOI	10.33594/000000083
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Article: Is Cyprideis agrigentina Decima a good paleosalinometer for the Messinian Salinity Crisis? Morphometrical and geochemical analyses from the Eraclea Minoa section (Sicily)

Grossi, F / E. Gliozzi / F. Castorina / M. Voltaggio / P. AnadÃ³n

Palaeogeography, palaeoclimatology, palaeoecology. 2015 Feb. 01, v. 419

2015

Abstract: The living euryhaline species Cyprideis torosa (Jones) undergoes morphometric variations in size, noding and sieve-pore shape linked to the environmental salinity. In particular it is known that salinity values around 8â9psu represent the ... ...

Abstract	The living euryhaline species Cyprideis torosa (Jones) undergoes morphometric variations in size, noding and sieve-pore shape linked to the environmental salinity. In particular it is known that salinity values around 8â9psu represent the osmoregulation threshold and also the turning point between smaller and greater valve dimensions and prevailingly noded against un-noded valves. The variation of the percentage of round-, elongate- and irregular-shaped sieve-pores on the valves has shown an empiric logarithmic correlation with the water salinity from 0 to 100psu. Due to this ecologically cued polymorphism, C. torosa represents an invaluable paleosalinometer for the Quaternary brackish basins.In this paper we attempt to verify whether the ecophenotypical behavior of the post-evaporitic Messinian species Cyprideis agrigentina Decima was comparable with that of Cyprideis torosa. To reach this goal, three morphometric characters have been analyzed: 1) size variability; 2) noding and ornamentation; and 3) variability of the percentage of the sieve-pore shapes. The paleoenvironmental interpretation was made using synecological and geochemical approaches [stable isotopes, trace elements, Sr-isotopes and natural radioactivity (NRD)]. For this study, the 250m-thick Messinian Lago-Mare succession of Eraclea Minoa (Agrigento, Sicily) was chosen for the presence of monotypic assemblages made only by C. agrigentina for around 70m of thickness.The results of the morphometric analyses showed that: 1) size variations are not related to the salinity changes recognized both from synecological and geochemical analyses; 2) no noded specimens have been recovered along the Section; 3) the salinities calculated on the basis of the percentage of the sieve-pore shape are not correlated with the salinities inferred from the synecological and geochemical analyses. Thus, in this paper we conclude that Cyprideis agrigentina cannot be considered a paleosalinometer for the Messinian Salinity Crisis.There is a correlation of the Î´13C with the percentages of sieve-pore shapes, linking them to the behavior of the dissolved inorganic carbon (DIC) and to the oxygen availability at the bottom of the basin.
Keywords	basins ; carbon ; dissolved inorganic carbon ; euryhaline species ; morphometry ; osmoregulation ; oxygen ; paleoecology ; stable isotopes ; trace elements ; water salinity ; Sicily
Language	English
Dates of publication	2015-0201
Size	p. 75-89.
Publishing place	Elsevier B.V.
Document type	Article
ZDB-ID	417718-6
ISSN	0031-0182
ISSN	0031-0182
DOI	10.1016/j.palaeo.2014.09.024
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Article: Geology and taphonomy of the L'Espinau dinosaur bonebed, a singular lagoonal site from the Maastrichtian of South-Central Pyrenees

Fondevilla, V / A. Vicente / A.G. SellÃ©s / Ã. Galobart / B. Vila / C. MartÃn-Closas / F. Battista / J. DinarÃ¨s-Turell / N.L. Razzolini / O. Oms / P. AnadÃ³n

Sedimentary geology. 2017 June 15, v. 355

2017

Abstract: The L'Espinau site is a dinosaur bonebed from the Upper Cretaceous of the South-Central Pyrenees (north-eastern Spain) that have provided hundreds of bone remains attributed to hadrosauroids, together with a rich assemblage of herpetofauna, fish and ... ...

Abstract	The L'Espinau site is a dinosaur bonebed from the Upper Cretaceous of the South-Central Pyrenees (north-eastern Spain) that have provided hundreds of bone remains attributed to hadrosauroids, together with a rich assemblage of herpetofauna, fish and microflora. Magnetostratigraphy calibrated the site with the early late Maastrichtian, and the combined sedimentology, stable isotope geochemistry and palaeoecology revealed that this fossil site formed in a lagoon, in which a mixed freshwater-brackish palaeoenvironment was developed. This setting displays a south-north charophyte zonation from freshwater (Clavator brachycerus-dominated assemblage) to brackish or eurihaline conditions (Feistiella malladae-dominated assemblage), revealing a palaeoenvironment change towards the coast. Sedimentology and taphonomy (bidirectional arrangement of long bones, abrasion and disarticulation) indicate that the L'Espinau site is the result of a cohesive mass flow event originated very close to the sea. This process entrained and mixed fauna from both the terrestrial and the brackish/marine environment of a lagoon. An increasing of the water runoff (e.g. by intense rainfall) reworking poorly consolidated sediments is considered here as the most probable triggering mechanism. Mass flow-hosted bonebeds are commonly linked to fluvial palaeoenvironments, so our study case is a rare example of bones accumulating near the sea. This study adds evidence that hadrosauroids inhabited littoral environments during the Maastrichtian in the southern Pyrenean area.
Keywords	bones ; Charophyta ; coasts ; fish ; fossils ; freshwater ; geochemistry ; herpetofauna ; littoral zone ; marine environment ; mass flow ; microorganisms ; paleoecology ; rain ; runoff ; sediments ; stable isotopes ; Spain
Language	English
Dates of publication	2017-0615
Size	p. 75-92.
Publishing place	Elsevier B.V.
Document type	Article
ZDB-ID	216739-6
ISSN	0037-0738
ISSN	0037-0738
DOI	10.1016/j.sedgeo.2017.03.014
Database	NAL-Catalogue (AGRICOLA)

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Article: Fucoid assemblages on the north coast of Spain: past and present (1977â2007)

Lamela-Silvarrey, Cristina / ConsolaciÃ³n FernÃ¡ndez / Julio Arrontes / Ricardo AnadÃ³n

Botanica marina. 2012 Mar. 05, v. 55, no. 3

2012

Abstract: Fucoid assemblages dominated by Pelvetia canaliculata, Fucus spiralis, F. vesiculosus, and ... for all the species in 2007, and there were differences in the timing of maximum biomass for P. canaliculata and F ... canaliculata and particularly F. vesiculosus, being the assemblages most sensitive to change. Observed ...

Abstract	Fucoid assemblages dominated by Pelvetia canaliculata, Fucus spiralis, F. vesiculosus, and Ascophyllum nodosum located at two sites on the central coast of Asturias (northern Spain) were sampled monthly in 1977. Repeating the same sampling methodology, a resurvey was done in 2007 to detect changes in the abundances of the species using the previous data as a baseline. Annual net primary production was lower for all the species in 2007, and there were differences in the timing of maximum biomass for P. canaliculata and F. vesiculosus, as well as a shortening of the growth period in 2007. Associated fauna also differed between dates. Higher abundances of Gibbula spp. occurred in 2007, whereas littorinid species densities in the upper intertidal were reduced in that year. As a result, the fucoid-grazers balance changed, with P. canaliculata and particularly F. vesiculosus, being the assemblages most sensitive to change. Observed modifications were not merely fluctuations in the biomass patterns of these species, but also responses to increases in air temperature and sea surface temperature and to a shift in the frequency and seasonality of upwelling episodes. Other long-term abiotic fluctuations not directly related to global warming should also be considered as possible drivers for these changes.
Keywords	air temperature ; Ascophyllum nodosum ; biomass ; coasts ; fauna ; Fucus spiralis ; global warming ; littoral zone ; Pelvetia canaliculata ; primary productivity ; surface water temperature ; Spain
Language	English
Dates of publication	2012-0305
Size	p. 199-207.
Publishing place	Walter de Gruyter
Document type	Article
ZDB-ID	1475447-2
ISSN	1437-4323 ; 0006-8055
ISSN (online)	1437-4323
ISSN	0006-8055
DOI	10.1515/bot-2011-0081
Database	NAL-Catalogue (AGRICOLA)

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Article: Alagille syndrome and deletion of 20p.

Anad, F / Burn, J / Matthews, D / Cross, I / Davison, B C / Mueller, R / Sands, M / Lillington, D M / Eastham, E

Journal of medical genetics

1990 Volume 27, Issue 12, Page(s) 729–737

Abstract: We add five cases of 20p deletion to the 10 cases already published. Four had craniofacial, vertebral, ocular, and cardiovascular features of Alagille syndrome, which adds weight to the assignment of this disorder to the short arm of chromosome 20. ... ...

Abstract	We add five cases of 20p deletion to the 10 cases already published. Four had craniofacial, vertebral, ocular, and cardiovascular features of Alagille syndrome, which adds weight to the assignment of this disorder to the short arm of chromosome 20. Included in our series is the first report of familial transmission of a 20p deletion.
MeSH term(s)	Abnormalities, Multiple/genetics ; Adolescent ; Adult ; Bone and Bones/abnormalities ; Child, Preschool ; Cholestasis/genetics ; Chromosome Banding ; Chromosome Deletion ; Chromosomes, Human, Pair 20 ; Eye Abnormalities/genetics ; Facial Bones/abnormalities ; Female ; Heart Defects, Congenital/genetics ; Humans ; Infant ; Kidney/abnormalities ; Male ; Skull/abnormalities ; Syndrome
Language	English
Publishing date	1990-12
Publishing country	England
Document type	Case Reports ; Journal Article ; Review
ZDB-ID	220881-7
ISSN	1468-6244 ; 0022-2593
ISSN (online)	1468-6244
ISSN	0022-2593
DOI	10.1136/jmg.27.12.729
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