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  1. Article ; Online: A new index for the diagnosis of outflow obstruction in hypertrophic cardiomyopathy: is it accurate? and if so, is it useful?

    Spirito, Paolo / Boni, Luca

    European heart journal. Cardiovascular Imaging

    2023  Volume 24, Issue 6, Page(s) 719–720

    MeSH term(s) Humans ; Ventricular Outflow Obstruction, Left ; Mitral Valve/physiopathology ; Ventricular Septum ; Cardiomyopathy, Hypertrophic/physiopathology ; Echocardiography
    Language English
    Publishing date 2023-04-04
    Publishing country England
    Document type Editorial ; Comment
    ZDB-ID 2638345-7
    ISSN 2047-2412 ; 2047-2404
    ISSN (online) 2047-2412
    ISSN 2047-2404
    DOI 10.1093/ehjci/jead055
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 5614: Show issues Location:
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  2. Article ; Online: Atrial Fibrillation in Hypertrophic Cardiomyopathy: New Light on an Old Problem.

    Spirito, Paolo

    Circulation

    2017  Volume 136, Issue 25, Page(s) 2437–2439

    MeSH term(s) Atrial Fibrillation ; Cardiomyopathy, Hypertrophic ; Humans
    Language English
    Publishing date 2017-12-15
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 80099-5
    ISSN 1524-4539 ; 0009-7322 ; 0069-4193 ; 0065-8499
    ISSN (online) 1524-4539
    ISSN 0009-7322 ; 0069-4193 ; 0065-8499
    DOI 10.1161/CIRCULATIONAHA.117.031743
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Saving More Lives.

    Spirito, Paolo

    Journal of the American College of Cardiology

    2017  Volume 69, Issue 7, Page(s) 774–776

    MeSH term(s) Cardiomyopathy, Hypertrophic ; Heart Aneurysm ; Humans ; Tachycardia, Ventricular
    Language English
    Publishing date 2017-02-16
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 605507-2
    ISSN 1558-3597 ; 0735-1097
    ISSN (online) 1558-3597
    ISSN 0735-1097
    DOI 10.1016/j.jacc.2016.12.010
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    Zs.A 1846: Show issues Location:
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    Zs.MO 196: Show issues

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  4. Article ; Online: The dawn of a better day for patients with hypertrophic cardiomyopathy.

    Spirito, Paolo

    Journal of the American College of Cardiology

    2015  Volume 65, Issue 18, Page(s) 1929–1930

    MeSH term(s) Cardiomyopathy, Hypertrophic/mortality ; Cardiomyopathy, Hypertrophic/therapy ; Female ; Humans ; Male
    Language English
    Publishing date 2015-05-12
    Publishing country United States
    Document type Comment ; Editorial
    ZDB-ID 605507-2
    ISSN 1558-3597 ; 0735-1097
    ISSN (online) 1558-3597
    ISSN 0735-1097
    DOI 10.1016/j.jacc.2015.03.516
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  5. Article ; Online: Differing strategies for sudden death prevention in hypertrophic cardiomyopathy.

    Maron, Martin S / Rowin, Ethan / Spirito, Paolo / Maron, Barry J

    Heart (British Cardiac Society)

    2023  Volume 109, Issue 8, Page(s) 589–594

    Abstract: Sudden death (SD) has traditionally been the most visible and feared complication of hypertrophic cardiomyopathy (HCM). Substantial progress in reducing the occurrence of these catastrophic events represents a new paradigm in disease management. ... ...

    Abstract Sudden death (SD) has traditionally been the most visible and feared complication of hypertrophic cardiomyopathy (HCM). Substantial progress in reducing the occurrence of these catastrophic events represents a new paradigm in disease management. Prevention of SD in HCM has resulted from introduction of primary prevention ICDs that reliably terminate life-threatening ventricular tachyarrhythmias, as well as a matured risk stratification algorithm capable of reliably identifying those patients at highest risk. This initiative has been a major determinant of reducing HCM-related mortality to a low rate of 0.5%/year. In such a heterogeneous heart disease as HCM, no perfect risk stratification strategy is possible, and available approaches differ in terms of sensitivity and specificity for identifying patients with SD risk. Major cardiovascular societies, American Heart Association/American College of Cardiology in the USA and European Society of Cardiology in Europe have promoted different risk stratification guidelines creating the potential for judging SD risk in a given HCM patient differently based on commitment to a particular societal guideline or country of residence. In this review, we provide a critical but balanced assessment of these two divergent SD prevention strategies with regard to their respective strengths and weaknesses, as a guide to clinicians directly engaged in this important management issue.
    MeSH term(s) Humans ; Risk Assessment ; Death, Sudden, Cardiac/etiology ; Death, Sudden, Cardiac/prevention & control ; Death, Sudden, Cardiac/epidemiology ; Defibrillators, Implantable/adverse effects ; Tachycardia, Ventricular/etiology ; Cardiomyopathy, Hypertrophic/complications ; Cardiomyopathy, Hypertrophic/diagnosis ; Cardiomyopathy, Hypertrophic/therapy ; Risk Factors
    Language English
    Publishing date 2023-03-27
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 1303417-0
    ISSN 1468-201X ; 1355-6037
    ISSN (online) 1468-201X
    ISSN 1355-6037
    DOI 10.1136/heartjnl-2020-316693
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.MO 112: Show issues

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  6. Article ; Online: Reply: Hypertrophic Cardiomyopathy as Congenital Heart Disease.

    Zyrianov, Aleksei / Spirito, Paolo / Ferrazzi, Paolo / Pezzoli, Laura / Iascone, Maria

    Journal of the American College of Cardiology

    2021  Volume 77, Issue 10, Page(s) 1378–1379

    MeSH term(s) Cardiomyopathy, Hypertrophic/complications ; Cardiomyopathy, Hypertrophic/diagnosis ; Heart Defects, Congenital/complications ; Heart Defects, Congenital/diagnosis ; Humans
    Language English
    Publishing date 2021-03-11
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 605507-2
    ISSN 1558-3597 ; 0735-1097
    ISSN (online) 1558-3597
    ISSN 0735-1097
    DOI 10.1016/j.jacc.2020.12.045
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    Zs.MO 196: Show issues

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  7. Article ; Online: We need more high-volume myectomy centres in Europe.

    Spirito, Paolo / Ferrazzi, Paolo

    European journal of heart failure

    2017  Volume 20, Issue 2, Page(s) 406–408

    MeSH term(s) Cardiac Surgical Procedures ; Cardiomyopathy, Hypertrophic ; Europe ; Heart Failure ; Humans ; Treatment Outcome
    Language English
    Publishing date 2017-11-21
    Publishing country England
    Document type Editorial ; Comment
    ZDB-ID 1483672-5
    ISSN 1879-0844 ; 1388-9842
    ISSN (online) 1879-0844
    ISSN 1388-9842
    DOI 10.1002/ejhf.1061
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    Zs.A 5299: Show issues Location:
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  8. Article ; Online: Long-Term Prognostic Implications of Conduction Abnormalities Following Septal Myectomy: What Do We Know?

    Spirito, Paolo / Fracchioni, Ilenia

    Journal of the American College of Cardiology

    2019  Volume 74, Issue 5, Page(s) 656–658

    MeSH term(s) Cardiac Conduction System Disease ; Cardiomyopathy, Hypertrophic ; Heart Septum ; Humans ; Prognosis
    Language English
    Publishing date 2019-08-01
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 605507-2
    ISSN 1558-3597 ; 0735-1097
    ISSN (online) 1558-3597
    ISSN 0735-1097
    DOI 10.1016/j.jacc.2019.05.054
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  9. Article ; Online: Mandibular Reconstruction after Resection of Ameloblastoma by Custom-Made CAD/CAM Mandibular Titanium Prosthesis: Two Case Reports, Finite Element Analysis and Discussion of the Technique.

    Cortese, Antonio / Spirito, Francesca / Claudio, Pier Paolo / Lo Muzio, Lorenzo / Ruggiero, Alessandro / Gargiulo, Maurizio

    Dentistry journal

    2023  Volume 11, Issue 4

    Abstract: Virtual surgical planning for CAD/CAM mandibular reconstruction by titanium prosthesis was recently reported for resected cases. Even if some advantages are evident, difficulties that may arise for TMJ function after reconstruction originate from ... ...

    Abstract Virtual surgical planning for CAD/CAM mandibular reconstruction by titanium prosthesis was recently reported for resected cases. Even if some advantages are evident, difficulties that may arise for TMJ function after reconstruction originate from prosthesis contamination through oral mucosa dehiscence. In these two cases reported of mandibular reconstruction after resection of ameloblastoma by custom-made CAD/CAM titanium prosthesis, the procedures were aimed to preserve the TMJ glenoid cavity and articular disc avoiding functional problems for hemi-mandibular resections that included the condyle (as in case #1) or with condylar preservation (as in case #2) and avoiding intraoral incisions in both cases. The entire surgical planning and prosthetic fabrication were explained with specifications and the sequence of the surgical procedure. Finite elements analysis (FEA) was performed to check the force distribution and efficacy of the prosthetic device (case 1 with hemi-mandibular resection and rehabilitation). Although successful in these two cases, surgical reconstruction of the mandibular defect after resection by a CAD-CAM custom-made prosthesis still shows some drawbacks and failure risks. Several advantages of this technique and the surgical success in these two cases were presented, but limitations and side effects must be considered when cases are selected.
    Language English
    Publishing date 2023-04-20
    Publishing country Switzerland
    Document type Case Reports
    ZDB-ID 2681351-8
    ISSN 2304-6767 ; 2304-6767
    ISSN (online) 2304-6767
    ISSN 2304-6767
    DOI 10.3390/dj11040106
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  10. Article ; Online: The challenge of diagnosing hypertrophic cardiomyopathy in patients of African descent.

    Spirito, Paolo / Ferrazzi, Paolo

    Heart (British Cardiac Society)

    2016  Volume 102, Issue 22, Page(s) 1777–1778

    Language English
    Publishing date 2016-09-27
    Publishing country England
    Document type Editorial
    ZDB-ID 1303417-0
    ISSN 1468-201X ; 1355-6037
    ISSN (online) 1468-201X
    ISSN 1355-6037
    DOI 10.1136/heartjnl-2016-310361
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