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  1. Article: Signal detection models as contextual bandits.

    Sherratt, Thomas N / O'Neill, Erica

    Royal Society open science

    2023  Volume 10, Issue 6, Page(s) 230157

    Abstract: Signal detection theory (SDT) has been widely applied to identify the optimal discriminative decisions of receivers under uncertainty. However, the approach assumes that decision-makers immediately adopt the appropriate acceptance threshold, even though ... ...

    Abstract Signal detection theory (SDT) has been widely applied to identify the optimal discriminative decisions of receivers under uncertainty. However, the approach assumes that decision-makers immediately adopt the appropriate acceptance threshold, even though the optimal response must often be learned. Here we recast the classical normal-normal (and power-law) signal detection model as a contextual multi-armed bandit (CMAB). Thus, rather than starting with complete information, decision-makers must infer how the magnitude of a continuous cue is related to the probability that a signaller is desirable, while simultaneously seeking to exploit the information they acquire. We explain how various CMAB heuristics resolve the trade-off between better estimating the underlying relationship and exploiting it. Next, we determined how naive human volunteers resolve signal detection problems with a continuous cue. As anticipated, a model of choice (accept/reject) that assumed volunteers immediately adopted the SDT-predicted acceptance threshold did not predict volunteer behaviour well. The Softmax rule for solving CMABs, with choices based on a logistic function of the expected payoffs, best explained the decisions of our volunteers but a simple midpoint algorithm also predicted decisions well under some conditions. CMABs offer principled parametric solutions to solving many classical SDT problems when decision-makers start with incomplete information.
    Language English
    Publishing date 2023-06-21
    Publishing country England
    Document type Journal Article
    ZDB-ID 2787755-3
    ISSN 2054-5703
    ISSN 2054-5703
    DOI 10.1098/rsos.230157
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Methodological considerations in the recruitment and analysis of schizotypy samples.

    Neill, Erica

    Frontiers in psychiatry

    2014  Volume 5, Page(s) 156

    Language English
    Publishing date 2014-11-06
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2564218-2
    ISSN 1664-0640
    ISSN 1664-0640
    DOI 10.3389/fpsyt.2014.00156
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Depressive symptoms are specifically related to speech pauses in schizophrenia spectrum disorders.

    Tan, Eric J / Neill, Erica / Kleiner, Jacqui L / Rossell, Susan L

    Psychiatry research

    2023  Volume 321, Page(s) 115079

    Abstract: Depression is a common and debilitating mental illness associated with sadness and negativity and is often comorbid with other psychiatric conditions, such as schizophrenia. Depressive symptoms are presently primarily assessed through clinical interviews, ...

    Abstract Depression is a common and debilitating mental illness associated with sadness and negativity and is often comorbid with other psychiatric conditions, such as schizophrenia. Depressive symptoms are presently primarily assessed through clinical interviews, however there are other behavioural indicators being investigated as more objective methods of depressive symptom assessment. The present study aimed to evaluate the utility of assessing depression using quantitative speech parameters by comparing speech between 23 schizophrenia/schizoaffective patients with clinically significant depressive symptoms (DP) 19 schizophrenia/schizoaffective patients without depressive symptoms (NDP) and 22 healthy controls with no psychiatric history (HC). Participant audio recordings were transcribed and analyzed to extract five types of speech variables: utterances, words, speaking rate, formulation errors and pauses. The results indicated that DP patients produced significantly more pauses within utterances, and had more utterances with pauses compared to NDP patients and HCs (p = <.05), who performed similarly to each other. Word, speaking rate and formulation errors variables were not significantly different between the patient groups (p > .05). The findings suggest that depressive symptoms may have a specific relationship to speech pauses, and support the potential future use of speech pause assessments as an alternative and objective depression rating and monitoring tool.
    MeSH term(s) Humans ; Speech ; Schizophrenia ; Depression
    Language English
    Publishing date 2023-01-27
    Publishing country Ireland
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 445361-x
    ISSN 1872-7123 ; 1872-7506 ; 0925-4927 ; 0165-1781
    ISSN (online) 1872-7123 ; 1872-7506
    ISSN 0925-4927 ; 0165-1781
    DOI 10.1016/j.psychres.2023.115079
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Experiences implementing a Radiation therapist-led oncology prehabilitation program during COVID-19

    Erica Bennett / Trish Clifford / Fiona Cregan / Ellen O'Neill / Donna Spillane / Kieran Harte / Mary Hickey / Paul J Kelly

    Technical Innovations & Patient Support in Radiation Oncology, Vol 29, Iss , Pp 100226- (2024)

    1481  

    Keywords Medical physics. Medical radiology. Nuclear medicine ; R895-920 ; Neoplasms. Tumors. Oncology. Including cancer and carcinogens ; RC254-282
    Language English
    Publishing date 2024-03-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article ; Online: Psychotic disorders amid the COVID-19 pandemic: a consideration of risks and impacts.

    Tan, Eric Josiah / Neill, Erica / Rossell, Susan Lee

    Current opinion in psychiatry

    2022  Volume 35, Issue 3, Page(s) 140–145

    Abstract: Purpose of review: The COVID-19 pandemic has had a severe and widespread global impact but particularly for those with psychosis. This review summarizes recent evidence on the relationship between the COVID-19 pandemic and psychotic disorders, ... ...

    Abstract Purpose of review: The COVID-19 pandemic has had a severe and widespread global impact but particularly for those with psychosis. This review summarizes recent evidence on the relationship between the COVID-19 pandemic and psychotic disorders, highlighting the risks faced by these individuals including the negative impacts on treatment services, complications from contracting COVID-19, and the acceptability of digital interventions.
    Recent findings: Mortality, morbidity, and infection outcomes are among the worst for individuals with psychotic disorders. Presentation rates for psychotic disorders are elevated at emergency departments compared with before the COVID-19 pandemic; demand for inpatient services has increased, and there have been complications in access because of pandemic restrictions. COVID-19 related stressors have led to the exacerbation and incidence of psychotic symptoms among individuals with and without preexisting psychotic diagnoses. Digital interventions may be an acceptable method for maintaining patient contact and treatment during extended isolation.
    Summary: More data is needed on the longitudinal trajectory for psychotic symptoms post-COVID-19 infection and pandemic restrictions to better support individuals with psychotic disorders. Development of a long-term pandemic management plan is needed to monitor and support psychiatric health across the population.
    MeSH term(s) COVID-19 ; Humans ; Pandemics ; Psychotic Disorders/epidemiology ; Psychotic Disorders/etiology ; Psychotic Disorders/therapy ; SARS-CoV-2
    Language English
    Publishing date 2022-02-07
    Publishing country United States
    Document type Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 645162-7
    ISSN 1473-6578 ; 0951-7367
    ISSN (online) 1473-6578
    ISSN 0951-7367
    DOI 10.1097/YCO.0000000000000784
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Corrigendum to: Semantic Memory Impairment Across the Schizophrenia Continuum: A Meta-Analysis of Category Fluency Performance.

    Tan, Eric Josiah / Neill, Erica / Tomlinson, Kiandra / Rossell, Susan Lee

    Schizophrenia bulletin open

    2021  Volume 2, Issue 1, Page(s) sgab018

    Abstract: This corrects the article DOI: 10.1093/schizbullopen/sgaa054.]. ...

    Abstract [This corrects the article DOI: 10.1093/schizbullopen/sgaa054.].
    Language English
    Publishing date 2021-06-04
    Publishing country United States
    Document type Published Erratum
    ISSN 2632-7899
    ISSN (online) 2632-7899
    DOI 10.1093/schizbullopen/sgab018
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Intersections of paranoia and the body in the general population.

    Toh, Wei Lin / Phillipou, Andrea / Neill, Erica / Rossell, Susan L

    Journal of health psychology

    2022  Volume 28, Issue 7, Page(s) 633–647

    Abstract: Negative body image may be associated with heightened feelings of paranoia. The current study aimed to conduct multidimensional assessments of body image and psychosis facets in the general population. Respondents were 407 individuals, who provided basic ...

    Abstract Negative body image may be associated with heightened feelings of paranoia. The current study aimed to conduct multidimensional assessments of body image and psychosis facets in the general population. Respondents were 407 individuals, who provided basic sociodemographic information, and completed online questionnaires evaluating dysmorphic concerns, body consciousness, paranoia, persecutory and magical ideation and perceptual aberration. Correlation analysis and a series of regressions onto various body image facets (i.e. dysmorphic concerns, private body consciousness, public body consciousness and body competence) were conducted. Distinct patterns of significant associations were uncovered across the range of body image and psychosis facets examined. Paranoia significantly contributed to the severity of dysmorphic concerns, and magical ideation significantly contributed to private and public body consciousness, though effect sizes were modest. Our findings corroborate the relationship between paranoia and dysmorphic concerns, and tentatively suggest that challenging paranoid beliefs could be a useful strategy for managing negative body image.
    MeSH term(s) Humans ; Paranoid Disorders/epidemiology ; Emotions ; Psychotic Disorders ; Interpersonal Relations ; Body Image
    Language English
    Publishing date 2022-10-29
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2021897-7
    ISSN 1461-7277 ; 1359-1053
    ISSN (online) 1461-7277
    ISSN 1359-1053
    DOI 10.1177/13591053221133890
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Alcohol Craving and Severity are Associated with Dorsal Anterior Cingulate Choline Levels in Individuals with an Alcohol Use Disorder.

    Grodin, Erica N / Burnette, Elizabeth M / O'Neill, Joseph / Alger, Jeffry / Ray, Lara A

    Alcohol and alcoholism (Oxford, Oxfordshire)

    2023  Volume 58, Issue 3, Page(s) 289–297

    Abstract: Aims: Magnetic resonance spectroscopy (MRS) has been used to probe inflammation in the brain. While altered MRS metabolite levels have previously been found in individuals with alcohol use disorder (AUD), the relationship between potential metabolite ... ...

    Abstract Aims: Magnetic resonance spectroscopy (MRS) has been used to probe inflammation in the brain. While altered MRS metabolite levels have previously been found in individuals with alcohol use disorder (AUD), the relationship between potential metabolite markers of inflammation and the clinical correlates of AUD remains understudied. Therefore, this exploratory study sought to elucidate the clinical significance of inflammation in AUD by examining relationships between metabolites, AUD severity, alcohol consumption, and craving in individuals with AUD.
    Methods: Data for this secondary analysis are derived from a two-week clinical trial of ibudilast to treat AUD. Forty-three non-treatment-seeking individuals with an AUD (26M/17F) completed an MRS scan and alcohol-related questionnaires. MRS was performed using a multi-voxel array placed above the corpus callosum, extending from the pregnenual anterior cingulate to premotor cortex. The dorsal anterior cingulate was selected as the volume of interest. Metabolite levels of choline-compounds (Cho), myo-inositol (mI), and creatine+phosphocreatine (Cr) were quantified. Separate hierarchical regression models were used to evaluate the independent effects of metabolite levels on alcohol craving, alcohol problem severity, and alcohol consumption.
    Results: Dorsal anterior cingulate Cho predicted alcohol craving and alcohol problem severity over and above demographics, medication, and alcohol consumption measures. mI and Cr did not predict alcohol craving or alcohol problem severity. Metabolite markers were not predictive of alcohol consumption.
    Conclusions: This preliminary study indicates that dACC Cho is sensitive to clinical characteristics of AUD. This is a further step in advancing neurometabolites, particularly Cho, as potential biomarkers and treatment targets for AUD.
    MeSH term(s) Humans ; Alcoholism/metabolism ; Gyrus Cinguli/diagnostic imaging ; Gyrus Cinguli/metabolism ; Craving ; Choline/metabolism ; Alcohol Drinking/metabolism ; Ethanol/metabolism ; Alcohol-Related Disorders ; Inositol/metabolism
    Chemical Substances Choline (N91BDP6H0X) ; Ethanol (3K9958V90M) ; Inositol (4L6452S749)
    Language English
    Publishing date 2023-03-20
    Publishing country England
    Document type Journal Article
    ZDB-ID 604956-4
    ISSN 1464-3502 ; 0309-1635 ; 0735-0414
    ISSN (online) 1464-3502
    ISSN 0309-1635 ; 0735-0414
    DOI 10.1093/alcalc/agad014
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Experiences implementing a Radiation therapist-led oncology prehabilitation program during COVID-19.

    Bennett, Erica / Clifford, Trish / Cregan, Fiona / O'Neill, Ellen / Spillane, Donna / Harte, Kieran / Hickey, Mary / Kelly, Paul J

    Technical innovations & patient support in radiation oncology

    2023  Volume 29, Page(s) 100226

    Abstract: Multi-modal prehabilitation prior to radiotherapy is valuable and achievable.•Radiation Therapists can be instrumental in developing prehab programs.•Multi-disciplinary care influences the patient's experience of cancer.•Validated screening tools can be ...

    Abstract •Multi-modal prehabilitation prior to radiotherapy is valuable and achievable.•Radiation Therapists can be instrumental in developing prehab programs.•Multi-disciplinary care influences the patient's experience of cancer.•Validated screening tools can be easily incorporated into pre-radiotherapy assessments.•Online delivery of a prehabilitation program is feasible and safe.
    Language English
    Publishing date 2023-11-30
    Publishing country England
    Document type Journal Article
    ISSN 2405-6324
    ISSN (online) 2405-6324
    DOI 10.1016/j.tipsro.2023.100226
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: A lack of repeatability creates the illusion of a trade-off between basal and plastic cold tolerance.

    O'Neill, Erica / Davis, Hannah E / MacMillan, Heath A

    Proceedings. Biological sciences

    2021  Volume 288, Issue 1964, Page(s) 20212121

    Abstract: The thermotolerance-plasticity trade-off hypothesis predicts that ectotherms with greater basal thermal tolerance have a lower acclimation capacity. This hypothesis has been tested at both high and low temperatures but the results often conflict. If ... ...

    Abstract The thermotolerance-plasticity trade-off hypothesis predicts that ectotherms with greater basal thermal tolerance have a lower acclimation capacity. This hypothesis has been tested at both high and low temperatures but the results often conflict. If basal tolerance constrains plasticity (e.g. through shared mechanisms that create physiological constraints), it should be evident at the level of the individual, provided the trait measured is repeatable. Here, we used chill-coma onset temperature and chill-coma recovery time (CCO and CCRT; non-lethal thermal limits) to quantify cold tolerance of
    MeSH term(s) Acclimatization/physiology ; Animals ; Cold Temperature ; Coma ; Drosophila melanogaster/physiology ; Illusions ; Plastics
    Chemical Substances Plastics
    Language English
    Publishing date 2021-12-08
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 209242-6
    ISSN 1471-2954 ; 0080-4649 ; 0962-8452 ; 0950-1193
    ISSN (online) 1471-2954
    ISSN 0080-4649 ; 0962-8452 ; 0950-1193
    DOI 10.1098/rspb.2021.2121
    Database MEDical Literature Analysis and Retrieval System OnLINE

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