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Article ; Online: Holiday Heart Confirmed: Alcohol-Associated Atrial Fibrillation.

Piano, Mariann R / Hwang, Chueh-Lung

2021 Volume 174, Issue 11, Page(s) 1616–1617

MeSH term(s)	Atrial Fibrillation/etiology ; Ethanol ; Holidays ; Humans
Chemical Substances	Ethanol (3K9958V90M)
Language	English
Publishing date	2021-08-31
Publishing country	United States
Document type	Editorial ; Comment
ZDB-ID	336-0
ISSN	1539-3704 ; 0003-4819
ISSN (online)	1539-3704
ISSN	0003-4819
DOI	10.7326/M21-3193
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Ua VI Zs.178/2: Show issues

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Article ; Online: Alcoholic Cardiomyopathy: Is it Time for Genetic Testing?

Piano, Mariann R

Journal of the American College of Cardiology

2018 Volume 71, Issue 20, Page(s) 2303–2305

MeSH term(s)	Cardiomyopathy, Alcoholic ; Cardiomyopathy, Dilated/genetics ; Cardiotoxicity ; Connectin/genetics ; Genetic Testing ; Humans
Chemical Substances	Connectin
Language	English
Publishing date	2018-06-08
Publishing country	United States
Document type	Editorial ; Comment
ZDB-ID	605507-2
ISSN	1558-3597 ; 0735-1097
ISSN (online)	1558-3597
ISSN	0735-1097
DOI	10.1016/j.jacc.2018.03.463
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Zs.A 1846: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (1.OG) ab Jg. 2022: Lesesaal (EG)
Zs.MO 196: Show issues

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Article ; Online: Age-Stratified Sex Differences in Heart Failure With Preserved Ejection Fraction Among Adult Hospitalizations.

Mogos, Mulubrhan F / Muchira, James M / Park, Chorong / Osmundson, Sarah / Piano, Mariann R

The Journal of cardiovascular nursing

2024

Abstract: Background: There is evidence that heart failure with preserved ejection fraction (HFpEF)-related hospitalizations are increasing in the United States. However, there is a lack of knowledge about HFpEF-related hospitalizations among younger adults.: ... ...

Abstract	Background: There is evidence that heart failure with preserved ejection fraction (HFpEF)-related hospitalizations are increasing in the United States. However, there is a lack of knowledge about HFpEF-related hospitalizations among younger adults. Objective: The aims of this study were to perform a retrospective analysis using the Nationwide Inpatient Sample and to examine age-stratified sex differences in the prevalence, correlates, and outcomes of HFpEF-related hospitalization across the adult life span. Method: Using the Nationwide Inpatient Sample (2002-2014), patient and hospital characteristics were determined. Joinpoint regression was used to describe age-stratified sex differences in the annual average percent change of hospitalizations with HFpEF. Survey logistic regression was used to estimate adjusted odds ratios representing the association of sex with HFpEF-related hospitalization and in-hospital mortality. Results: There were 8 599 717 HFpEF-related hospitalizations (2.43% of all hospitalizations). Women represented the majority (5 459 422 [63.48%]) of HFpEF-related adult hospitalizations, compared with men (3 140 295 [36.52%]). Compared with men younger than 50 years, women within the same age group were 6% to 28% less likely to experience HFpEF-related hospitalization. Comorbidities such as hypertensive heart disease, renal disease, hypertension, obstructive sleep apnea, atrial fibrillation, obesity, anemia, and pulmonary edema explained a greater proportion of the risk of HFpEF-related hospitalization in adults younger than 50 years than in adults 50 years or older. Conclusion: Before the age of 50 years, women exhibit lower HFpEF-related hospitalization than men, a pattern that reverses with advancing age. Understanding and addressing the factors contributing to these sex-specific differences can have several potential implications for improving women's cardiovascular health.
Language	English
Publishing date	2024-01-11
Publishing country	United States
Document type	Journal Article
ZDB-ID	639335-4
ISSN	1550-5049 ; 0889-4655
ISSN (online)	1550-5049
ISSN	0889-4655
DOI	10.1097/JCN.0000000000001069
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Zs.A 2315: Show issues

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Article ; Online: Alcohol's Effects on the Cardiovascular System.

Piano, Mariann R

Alcohol research : current reviews

2017 Volume 38, Issue 2, Page(s) 219–241

Abstract: Alcohol use has complex effects on cardiovascular (CV) health. The associations between drinking and CV diseases such as hypertension, coronary heart disease, stroke, peripheral arterial disease, and cardiomyopathy have been studied extensively and are ... ...

Abstract	Alcohol use has complex effects on cardiovascular (CV) health. The associations between drinking and CV diseases such as hypertension, coronary heart disease, stroke, peripheral arterial disease, and cardiomyopathy have been studied extensively and are outlined in this review. Although many behavioral, genetic, and biologic variants influence the interconnection between alcohol use and CV disease, dose and pattern of alcohol consumption seem to modulate this most. Low-to-moderate alcohol use may mitigate certain mechanisms such as risk and hemostatic factors affecting atherosclerosis and inflammation, pathophysiologic processes integral to most CV disease. But any positive aspects of drinking must be weighed against serious physiological effects, including mitochondrial dysfunction and changes in circulation, inflammatory response, oxidative stress, and programmed cell death, as well as anatomical damage to the CV system, especially the heart itself. Both the negative and positive effects of alcohol use on particular CV conditions are presented here. The review concludes by suggesting several promising avenues for future research related to alcohol use and CV disease. These include using direct biomarkers of alcohol to confirm self-report of alcohol consumption levels; studying potential mediation of various genetic, socioeconomic, and racial and ethnic factors that may affect alcohol use and CV disease; reviewing alcohol-medication interactions in cardiac patients; and examining CV effects of alcohol use in young adults and in older adults.
MeSH term(s)	Alcohol Drinking/adverse effects ; Alcoholism/complications ; Animals ; Cardiovascular Diseases/etiology ; Cardiovascular Diseases/metabolism ; Cardiovascular Diseases/pathology ; Cardiovascular Diseases/physiopathology ; Humans
Language	English
Publishing date	2017
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	2677485-9
ISSN	2169-4796 ; 1930-0573 ; 2168-3492 ; 0090-838X
ISSN (online)	2169-4796 ; 1930-0573
ISSN	2168-3492 ; 0090-838X
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Zs.B 2180: Show issues

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Article ; Online: Hazardous alcohol use, drinking motives and COVID-19-related anxiety in college students.

Delaney, Kendra / Dietrich, Mary S / Corte, Collen / Akard, Terrah Foster / Piano, Mariann R

Journal of American college health : J of ACH

2023 , Page(s) 1–10

Abstract: Objective: This study examined the associations of anxiety and drinking motives with hazardous and binge alcohol use among young adults.: Participants: We recruited young adults (N = 182, mean age 25) between November 2020 and December 2020.: ... ...

Abstract	Objective: This study examined the associations of anxiety and drinking motives with hazardous and binge alcohol use among young adults. Participants: We recruited young adults (N = 182, mean age 25) between November 2020 and December 2020. Methods: Linear regressions were used to evaluate relationships among hazardous alcohol use (US Alcohol Use Disorders Identification Test-C [USAUDIT-C]), binge drinking (Alcohol Intake Questionnaire [AIQ]), PROMIS-Anxiety, COVID-19 related anxiety (CAS), and the drinking to cope with depression and anxiety subscales of the Modified Drinking Motives Questionnaire. Results: Sixty-two percent of participants reported hazardous drinking (USAUDIT-C score > 4). PROMIS Anxiety and CAS scores were 63.7 and 1.0, respectively. Scores were positively associated with drinking patterns. However, the drinking to cope with depression motive significantly mediated these associations. Conclusions: After the onset of the pandemic, hazardous and binge drinking patterns among young adults were associated with drinking to cope with depression rather than anxiety.
Language	English
Publishing date	2023-04-13
Publishing country	United States
Document type	Journal Article
ZDB-ID	604907-2
ISSN	1940-3208 ; 0744-8481
ISSN (online)	1940-3208
ISSN	0744-8481
DOI	10.1080/07448481.2023.2198022
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Zs.A 427: Show issues

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Article ; Online: Time to Promote the Awareness of Unhealthy Alcohol Use Among Women.

Hwang, Chueh-Lung / Phillips, Shane A / Tu, Min-Hsuan / Piano, Mariann R

Journal of women's health (2002)

2021 Volume 31, Issue 1, Page(s) 1–3

MeSH term(s)	Alcohol Drinking/epidemiology ; Alcohol-Related Disorders ; Alcoholism/diagnosis ; Alcoholism/epidemiology ; Female ; Humans
Language	English
Publishing date	2021-12-17
Publishing country	United States
Document type	Editorial ; Research Support, N.I.H., Extramural
ZDB-ID	1139774-3
ISSN	1931-843X ; 1059-7115 ; 1540-9996
ISSN (online)	1931-843X
ISSN	1059-7115 ; 1540-9996
DOI	10.1089/jwh.2021.0546
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Zs.A 3584: Show issues

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Article ; Online: The effects of alcohol consumption on flow-mediated dilation in humans: A systematic review.

Hwang, Chueh-Lung / Piano, Mariann R / Phillips, Shane A

Physiological reports

2021 Volume 9, Issue 10, Page(s) e14872

Abstract: Changes in endothelial function may contribute to the positive and negative effects of alcohol consumption on cardiovascular conditions, such as hypertension and coronary artery disease. Numerous studies have used brachial artery flow-mediated dilation ( ... ...

Abstract	Changes in endothelial function may contribute to the positive and negative effects of alcohol consumption on cardiovascular conditions, such as hypertension and coronary artery disease. Numerous studies have used brachial artery flow-mediated dilation (FMD) to examine the effects of alcohol consumption on endothelial function in humans. However, the findings are inconsistent and may be due to multiple factors such as heterogeneity in subject characteristics, the alcohol use pattern, and amount/dose of alcohol consumed. Therefore, the aim of this systematic review was to investigate the effect of alcohol consumption on brachial artery FMD in humans considering the above-mentioned factors. This review found that while light to moderate alcohol consumption may have minimal effects on FMD, heavy alcohol consumption was associated with a decrease in FMD. However, most of the published studies included healthy, younger, and male individuals, limiting generalizability to other populations. Future studies should include more women, older subjects, and those from diverse and underrepresented backgrounds.
MeSH term(s)	Alcohol Drinking/adverse effects ; Alcohol Drinking/physiopathology ; Alcohol Drinking/trends ; Blood Flow Velocity/physiology ; Brachial Artery/physiopathology ; Humans ; Randomized Controlled Trials as Topic/methods ; Vasodilation/physiology
Language	English
Publishing date	2021-05-27
Publishing country	United States
Document type	Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't ; Systematic Review
ZDB-ID	2724325-4
ISSN	2051-817X ; 2051-817X
ISSN (online)	2051-817X
ISSN	2051-817X
DOI	10.14814/phy2.14872
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Article ; Online: Pregnancy-associated takotsubo cardiomyopathy hospitalizations in the United States.

Mogos, Mulubrhan F / Ahn, Soojung / Muchira, James M / Osmundson, Sarah / Piano, Mariann R

American journal of physiology. Heart and circulatory physiology

2023 Volume 325, Issue 3, Page(s) H468–H474

Abstract: Takotsubo cardiomyopathy (TCM) is most common not only in postmenopausal women aged ≥50 yr but also in pregnant individuals. However, there are no national estimates on the prevalence, timing of occurrence, correlates, and outcomes of pregnancy- ... ...

Abstract	Takotsubo cardiomyopathy (TCM) is most common not only in postmenopausal women aged ≥50 yr but also in pregnant individuals. However, there are no national estimates on the prevalence, timing of occurrence, correlates, and outcomes of pregnancy-associated TCM. Using the Nationwide Inpatient Sample (NIS: 2016-2020), we describe rates of pregnancy-associated TCM hospitalizations among 13- to 49-yr-old pregnant individuals in the United States by selected demographic, behavioral, hospital, and clinical characteristics. Joinpoint regression was used to describe the annual average percent change of pregnancy-associated TCM hospitalizations. Survey logistic regression was used to measure the association of pregnancy-associated TCM hospitalizations with maternal outcomes. Of the 19,754,535 pregnancy-associated hospitalizations, 590 were TCM associated. The overall trend in pregnancy-associated TCM hospitalizations remained stable during the study period. The majority of TCM occurred during the postpartum, followed by antepartum and delivery-associated hospitalizations. When compared with pregnancy hospitalizations without TCM, those with TCM were more likely to be over the age of 35 yr and use tobacco and opioids. Comorbidities during TCM-associated pregnancy hospitalizations included heart failure, coronary artery disease, hemorrhagic stroke, and hypertension. After controlling for potential confounders, the odds of pregnancy-associated TCM hospitalizations were 98.7 times [adjusted odds ratio (aOR) = 98.66, 95% confidence interval (CI) 31.23-311.64] and 14.7 times (aOR = 14.75, 95% CI 9.99-21.76) higher for experiencing in-hospital mortality and a prolonged hospital stay, respectively, than those without TCM. Although rare, pregnancy-associated TCM hospitalization is more likely to occur during the postpartum period and is associated with in-hospital mortality and prolonged hospital stay.
MeSH term(s)	Pregnancy ; Humans ; Female ; United States/epidemiology ; Takotsubo Cardiomyopathy/diagnosis ; Takotsubo Cardiomyopathy/epidemiology ; Hospitalization ; Comorbidity ; Heart Failure/epidemiology
Language	English
Publishing date	2023-07-07
Publishing country	United States
Document type	Journal Article
ZDB-ID	603838-4
ISSN	1522-1539 ; 0363-6135
ISSN (online)	1522-1539
ISSN	0363-6135
DOI	10.1152/ajpheart.00262.2023
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Article ; Online: Alcohol Consumption: A New Risk Factor for Arterial Stiffness?

Hwang, Chueh-Lung / Muchira, James / Hibner, Brooks A / Phillips, Shane A / Piano, Mariann R

Cardiovascular toxicology

2022 Volume 22, Issue 3, Page(s) 236–245

Abstract: The relationship between alcohol consumption and cardiovascular disease risk is complex. Low-to-moderate daily alcohol consumption (1-2 drinks/day) is associated with reduced risk, whereas greater amounts of alcohol consumption and a "binge" pattern of ... ...

Abstract	The relationship between alcohol consumption and cardiovascular disease risk is complex. Low-to-moderate daily alcohol consumption (1-2 drinks/day) is associated with reduced risk, whereas greater amounts of alcohol consumption and a "binge" pattern of drinking are associated with increased cardiovascular risk and mortality. Arterial stiffness may help explain the complex relationship. This integrated review summarizes data from studies examining the associations between alcohol consumption and pulse wave velocity, a gold standard measure of arterial stiffness. We also briefly review the concept and methodology of pulse wave velocity measurement as well as the mechanisms of alcohol-induced arterial stiffening. Findings among the different studies reviewed were inconsistent with methodological challenges related to alcohol use assessment. While making specific conclusions regarding this relationship is tenuous; the data suggest that excessive alcohol consumption or a binge drinking pattern is associated with increased arterial stiffness.
MeSH term(s)	Alcohol Drinking/adverse effects ; Arteries ; Pulse Wave Analysis ; Risk Factors ; Vascular Stiffness
Language	English
Publishing date	2022-02-23
Publishing country	United States
Document type	Journal Article ; Research Support, N.I.H., Extramural ; Review
ZDB-ID	2036765-X
ISSN	1559-0259 ; 1530-7905
ISSN (online)	1559-0259
ISSN	1530-7905
DOI	10.1007/s12012-022-09728-8
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Zs.A 5817: Show issues

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Article ; Online: Assessing postgraduate outcomes of research-intensive nursing science PhD programs: Methods and metrics.

Stolldorf, Deonni P / Schirle, Lori / Kleinpell, Ruth / Akard, Terrah Foster / Piano, Mariann R

Nursing outlook

2022 Volume 70, Issue 3, Page(s) 506–512

Abstract: Background: Across disciplines and within higher educational systems, assessing postgraduate outcomes is essential for evaluating doctoral programs, including research-intensive nursing science doctoral programs. However, there are limited reports ... ...

Abstract	Background: Across disciplines and within higher educational systems, assessing postgraduate outcomes is essential for evaluating doctoral programs, including research-intensive nursing science doctoral programs. However, there are limited reports regarding methods and metrics related to postgraduate longitudinal evaluation of research-focused nursing doctoral programs. Purpose: The purpose of this paper is to summarize studies in the area of postgraduate outcome assessment and provide recommendations regarding outcome methods and metrics for evaluating the effectiveness of research-focused nursing doctoral programs. Methods: PubMed/Medline, CINHAL Complete, and Google Scholar databases were searched using key words including PhD program, doctoral program, longitudinal evaluation, evaluation, program evaluation, PhD alumni survey, education outcomes and PhD program outcomes. We excluded non-English and full-text articles that were not available for review. Discussion: Based on a review of the literature, there are few reports on methods and questionnaires for postgraduate outcome assessment. There is a critical need to develop standardized core metrics/questions, longitudinal assessments, and a shared data repository. The latter will allow for comparisons across nursing doctoral programs. Conclusion: Robust standardized longitudinal assessment of nursing doctoral programs is a necessary step for comparison across programs and re-envisioning the nursing doctoral education of the future.
MeSH term(s)	Benchmarking ; Education, Nursing, Graduate ; Faculty, Nursing ; Forecasting ; Humans ; Program Evaluation/methods ; Surveys and Questionnaires
Language	English
Publishing date	2022-04-13
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	300568-9
ISSN	1528-3968 ; 0029-6554
ISSN (online)	1528-3968
ISSN	0029-6554
DOI	10.1016/j.outlook.2022.02.012
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