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Article ; Online: Shields M., Carroll M.D., Ogden C.L. adult obesity prevalence in Canada and the United States. NCHS data brief no. 56, Hyattsville, MD: National Center for Health Statistics, 2011.

McGuire, Shelley

2011 Volume 2, Issue 4, Page(s) 368–369

MeSH term(s)	Canada/epidemiology ; Humans ; National Center for Health Statistics, U.S. ; Obesity/epidemiology ; United States/epidemiology
Language	English
Publishing date	2011-06-28
Publishing country	United States
Document type	Comparative Study ; Journal Article
ZDB-ID	2583634-1
ISSN	2156-5376 ; 2156-5376
ISSN (online)	2156-5376
ISSN	2156-5376
DOI	10.3945/an.111.000497
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Chemical Recycling of Commercial Poly(l-lactic acid) to l-Lactide Using a High-Performance Sn(II)/Alcohol Catalyst System.

McGuire, Thomas M / Buchard, Antoine / Williams, Charlotte

Journal of the American Chemical Society

2023 Volume 145, Issue 36, Page(s) 19840–19848

Abstract: Poly(l-lactic acid) (PLLA) is a leading commercial polymer produced from biomass, showing useful ... postconsumer waste PLLA chemical recycling to monomer (CRM), i.e., the formation of l-lactide (l-LA) from waste ... applied with nonvolatile commercial alcohol, enables highly efficient CRM of PLLA to yield l-LA ...

Abstract	Poly(l-lactic acid) (PLLA) is a leading commercial polymer produced from biomass, showing useful properties for plastics and fiber applications; after use, it is compostable. One area for improvement is postconsumer waste PLLA chemical recycling to monomer (CRM), i.e., the formation of l-lactide (l-LA) from waste plastic. This process is currently feasible at high reaction temperatures and shows low catalytic activity accompanied, in some cases, by side reactions, including epimerization. Here, a commercial Sn(II) catalyst, applied with nonvolatile commercial alcohol, enables highly efficient CRM of PLLA to yield l-LA in excellent yield and purity (92% yield, >99% l-LA from theoretical max.). The depolymerization is performed using neat polymer films at low temperatures (160 °C) under a nitrogen flow or vacuum. The chemical recycling operates with outstanding activity, achieving turnover frequencies which are up to 3000× higher than previously excellent catalysts and applied at loadings up to 6000× lower than previously leading catalysts. The catalyst system achieves a TOF = 3000 h
Language	English
Publishing date	2023-08-31
Publishing country	United States
Document type	Journal Article
ZDB-ID	3155-0
ISSN	1520-5126 ; 0002-7863
ISSN (online)	1520-5126
ISSN	0002-7863
DOI	10.1021/jacs.3c05863
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: An Investigation of Employment Hope as a Key Factor Influencing Perceptions of Subjective Recovery among Adults with Serious Mental Illness Seeking Community Work.

Kukla, Marina / McGuire, Alan B / Weber, Kenneth C / Hatfield, Jessi / Henry, Nancy / Kulesza, Eric / Rollins, Angela L

Behavioral sciences (Basel, Switzerland)

2024 Volume 14, Issue 3

Abstract: Introduction: Employment is an important contributor to recovery in people with serious mental illness (SMI), yet studies have not explored how subjective elements of employment hope contribute to perceptions of global recovery in this population.: ... ...

Abstract	Introduction: Employment is an important contributor to recovery in people with serious mental illness (SMI), yet studies have not explored how subjective elements of employment hope contribute to perceptions of global recovery in this population. Methods: The current study examined the relationship between employment hope and subjective recovery in 276 unemployed adults with SMI participating in a multi-site clinical trial of a cognitive behavioral group intervention tailored toward work and combined with vocational rehabilitation. Participants had diagnoses of schizophrenia spectrum, bipolar, depressive, and posttraumatic stress disorders, and were receiving services at three Veterans Affairs healthcare facilities in the United States. Data were collected at study baseline. Linear regression analysis examined the relationship between employment hope (Short Employment Hope Scale; EHS-14) and subjective recovery (Recovery Assessment Scale; RAS) after controlling for psychiatric symptom severity and mental-health-related burden on daily life. Results: After accounting for covariates, employment hope significantly contributed to the regression model explaining subjective recovery. The overall model of predictor variables explained 52.5% of the variance in recovery. The results further explore the relationships between EHS-14 and RAS subscales. Conclusions: The findings suggest that employment hope is a key intervention target to bolster subjective recovery in this vulnerable population.
Language	English
Publishing date	2024-03-19
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2651997-5
ISSN	2076-328X
ISSN	2076-328X
DOI	10.3390/bs14030246
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Consumer perception, knowledge, and uses of cannabidiol.

Nguyen, Cambrey / Moeller, Karen E / McGuire, Michael / Melton, Brittany L

The mental health clinician

2023 Volume 13, Issue 5, Page(s) 217–224

Abstract: Introduction: The legalization of cannabidiol (CBD) across the United States, in varying degrees, has made CBD easily accessible to consumers for complementary and medical purposes. However, there is a paucity of scientific evidence on the benefits and ... ...

Abstract	Introduction: The legalization of cannabidiol (CBD) across the United States, in varying degrees, has made CBD easily accessible to consumers for complementary and medical purposes. However, there is a paucity of scientific evidence on the benefits and risks of commercially available CBD. In the literature, 2 studies have gathered consumer perceptions and attitudes on cannabis products, specifically CBD, using survey-based questionnaires. This study aimed to build on the aforementioned studies in obtaining consumer perception and knowledge of CBD products using a national survey-based questionnaire. Methods: Respondents were recruited through an anonymous, nationwide, online survey administered through Qualtrics in the United States from March 28 to April 30, 2021. The survey consisted of demographics, perceived efficacy and safety of CBD, and resources to obtain CBD information. The survey responses were reported using descriptive statistics along with median and interquartile range for the Likert portion. Results: A total of 1158 respondents accessed the survey. The median age was 43 and 50% of respondents were female. The uses for CBD included neurological disorders, pulmonary conditions, gastrointestinal disorders, and chronic pain. The most commonly reported safety concern related to taking CBD was anxiety. Participants agreed that CBD is safe when used responsibly for medical use, and social media was the main source used to obtain information about CBD. Discussion: Respondents who used CBD for a condition thought it was helpful; however, most of the adverse effects were rated as moderate to severe, requiring medical attention from a health care professional, hospital, or emergency room visit.
Language	English
Publishing date	2023-10-02
Publishing country	United States
Document type	Journal Article
ISSN	2168-9709
ISSN (online)	2168-9709
DOI	10.9740/mhc.2023.10.217
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Activity of Type II RAF Inhibitor Tovorafenib in a Pediatric Patient With a Recurrent Spindle Cell Sarcoma Harboring a Novel

Offer, Katharine / McGuire, Michael T / Song, Kunchang / Goldfischer, Michael J / Davare, Monika A / Corless, Christopher L / Beadling, Carol / Neff, Tanaya / Cox, Michael C / Govinda Raju, Sandya / Blackman, Samuel C

JCO precision oncology

2024 Volume 7, Page(s) e2300065

MeSH term(s)	Child ; Humans ; Biomarkers, Tumor/genetics ; Gene Fusion ; Neoplasm Recurrence, Local/drug therapy ; Neoplasm Recurrence, Local/genetics ; Proto-Oncogene Proteins B-raf/genetics ; Sarcoma/drug therapy ; Sarcoma/genetics ; Sorting Nexins/genetics
Chemical Substances	Biomarkers, Tumor ; BRAF protein, human (EC 2.7.11.1) ; Proto-Oncogene Proteins B-raf (EC 2.7.11.1) ; SNX8 protein, human ; Sorting Nexins ; tovorafenib (ZN90E4027M)
Language	English
Publishing date	2024-03-25
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ISSN	2473-4284
ISSN (online)	2473-4284
DOI	10.1200/PO.23.00065
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Cannabis use, decision making, and perceptions of risk among breastfeeding individuals: the Lactation and Cannabis (LAC) Study.

Smith, Caroline B / Schmidt, Jenna / Holdsworth, Elizabeth A / Caffé, Beatrice / Brooks, Olivia / Williams, Janet E / Gang, David R / McGuire, Mark A / McGuire, Michelle K / Barbosa-Leiker, Celestina / Meehan, Courtney L

Journal of cannabis research

2024 Volume 6, Issue 1, Page(s) 6

Abstract: Objective: Our primary objective was to understand breastfeeding individuals' decisions to use cannabis. Specifically, we investigated reasons for cannabis use, experiences with healthcare providers regarding use, and potential concerns about cannabis ... ...

Abstract	Objective: Our primary objective was to understand breastfeeding individuals' decisions to use cannabis. Specifically, we investigated reasons for cannabis use, experiences with healthcare providers regarding use, and potential concerns about cannabis use. Methods: We collected survey data from twenty breastfeeding participants from Washington and Oregon who used cannabis at least once weekly. We documented individuals' cannabis use and analyzed factors associated with their decisions to use cannabis during lactation. Qualitative description was used to assess responses to an open-ended question about potential concerns. Results: Fifty-five percent of participants (n = 11) reported using cannabis to treat or manage health conditions, mostly related to mental health. Eighty percent of participants (n = 16) reported very few or no concerns about using cannabis while breastfeeding, although participants who used cannabis for medical purposes had significantly more concerns. Most participants (n = 18, 90%) reported receiving either no or unhelpful advice from healthcare providers. Four themes arose through qualitative analysis, indicating that breastfeeding individuals are: 1) identifying research gaps and collecting evidence; 2) monitoring their child's health and development; 3) monitoring and titrating their cannabis use; and 4) comparing risks between cannabis and other controlled substances. Conclusions: Breastfeeding individuals reported cannabis for medical and non-medical reasons and few had concerns about cannabis use during breastfeeding. Breastfeeding individuals reported using a variety of strategies and resources in their assessment of risk or lack thereof when deciding to use cannabis. Most participants reported receiving no helpful guidance from healthcare providers.
Language	English
Publishing date	2024-02-16
Publishing country	England
Document type	Journal Article
ISSN	2522-5782
ISSN (online)	2522-5782
DOI	10.1186/s42238-023-00212-w
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: The longitudinal association of adverse events and working memory among preschoolers: A random-intercept cross-lag analysis.

Griffith, Rebecca L / McGuire, Austen / Guler, Jessy / Nowalis, Sarah / Jackson, Yo

Psychological trauma : theory, research, practice and policy

2024

Abstract	Objective: Past research examining the relation between adversity and working memory (WM) has found mixed results and has been limited by methodological issues (e.g., cross-sectional studies, limited measurement of adversity). The present study examined how adverse life events may impact WM among preschoolers who live in financially underresourced families and communities longitudinally over the course of 1 year. Method: The sample included 325 children (aged 3-5 at baseline), recruited because of their increased risk of exposure to high levels of adversity, and their primary caregivers. Children completed WM tasks and caregivers reported on their child's exposure to adverse events in the past 6 months across three time points, each time point occurring 6 months apart. Associations between adverse life events and WM over time were explored using a random-intercept cross-lagged panel model. Results: No relations between preschoolers' adverse event exposure and WM ( Conclusion: Results indicated that at the individual level, when controlling for stable covariates, frequency of adverse life event exposure and WM abilities were unrelated to subsequent frequency of adverse event exposure and WM abilities. Findings suggest that WM may continue to develop typically, in the preschool years, despite exposure to adverse life events. (PsycInfo Database Record (c) 2024 APA, all rights reserved).
Language	English
Publishing date	2024-03-21
Publishing country	United States
Document type	Journal Article
ZDB-ID	2497028-1
ISSN	1942-969X ; 1942-9681
ISSN (online)	1942-969X
ISSN	1942-9681
DOI	10.1037/tra0001682
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Editorial: Group norms and moral development: Reasoning and cognition across the lifespan.

Conry-Murray, Clare / McGuire, Luke / Hitti, Aline / Beißert, Hanna

Frontiers in psychology

2022 Volume 13, Page(s) 1035999

Language	English
Publishing date	2022-10-13
Publishing country	Switzerland
Document type	Editorial
ZDB-ID	2563826-9
ISSN	1664-1078
ISSN	1664-1078
DOI	10.3389/fpsyg.2022.1035999
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Article ; Online: Patterns of opioid use behaviors among patients seen in the emergency department: Latent class analysis of baseline data from the POINT pragmatic trial.

Bray, Bethany C / Watson, Dennis P / Salisbury-Afshar, Elizabeth / Taylor, Lisa / McGuire, Alan

Journal of substance use and addiction treatment

2023 Volume 146, Page(s) 208979

Abstract: Introduction: The nation's overdose epidemic has been characterized by increasingly potent opioids resulting in more emergency department (ED) encounters over time. ED-based opioid use interventions are growing in popularity; however, they tend to treat ...

Abstract	Introduction: The nation's overdose epidemic has been characterized by increasingly potent opioids resulting in more emergency department (ED) encounters over time. ED-based opioid use interventions are growing in popularity; however, they tend to treat people who use opioids as a homogenous population. The current study sought to understand heterogeneity among people who use opioids who encounter the ED by identifying qualitatively different subgroups among participants in an opioid use intervention clinical trial at baseline and examining associations between subgroup membership and multiple correlates. Methods: Participants were from a larger pragmatic clinical trial of the Planned Outreach, Intervention, Naloxone, and Treatment (POINT) intervention (n = 212; 59.2 % male, 85.3 % Non-Hispanic White, mean age = 36.6 years). The study employed latent class analysis (LCA) using five indicators of opioid use behavior: preference for opioids, preference for stimulants, usually use drugs alone, injection drug use, and opioid-related problem at ED encounter. Correlates of interest included participants' demographics, prescription histories, health care contact histories, and recovery capital (e.g., social support, naloxone knowledge). Results: The study identified three classes: (1) noninjecting opioid preferers, (2) injecting opioid and stimulant preferers, and (3) social nonopioid preferers. We identified limited significant differences in correlates across the classes: differences existed for select demographics, prescription histories, and recovery capital but not for health care contact histories. For example, members of Class 1 were the most likely to be a race/ethnicity other than non-Hispanic White, oldest on average, and most likely to have received a benzodiazepine prescription, whereas members of Class 2 had the highest average barriers to treatment and members of Class 3 were the least likely to have been diagnosed with a major mental health illness and had the lowest average barriers to treatment. Conclusions: LCA identified distinct subgroups among POINT trial participants. Knowledge of such subgroups assists with the development of better-targeted interventions and can help staff to identify the most appropriate treatment and recovery pathways for patients.
MeSH term(s)	Humans ; Male ; Adult ; Female ; Naloxone/therapeutic use ; Analgesics, Opioid/therapeutic use ; Latent Class Analysis ; Opioid-Related Disorders/epidemiology ; Emergency Service, Hospital
Chemical Substances	Naloxone (36B82AMQ7N) ; Analgesics, Opioid
Language	English
Publishing date	2023-02-09
Publishing country	United States
Document type	Journal Article ; Research Support, N.I.H., Extramural
ISSN	2949-8759
ISSN (online)	2949-8759
DOI	10.1016/j.josat.2023.208979
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Biopsychosocial Correlates and Individual Differences for Eliciting Moral Elevation in Veterans With PTSD: An Experimental Case Series.

McGuire, Adam P / Howard, Binh An N / Burns, Christina / Zambrano-Vazquez, Laura / Szabo, Yvette Z

The Journal of nervous and mental disease

2023 Volume 212, Issue 1, Page(s) 33–42

Abstract: Abstract: A promising approach to enhancing trauma-focused treatment is moral elevation-feeling inspired by witnessing a virtuous act. This study explored potential links between eliciting elevation and relevant outcomes in a series of case examples. ... ...

Abstract	Abstract: A promising approach to enhancing trauma-focused treatment is moral elevation-feeling inspired by witnessing a virtuous act. This study explored potential links between eliciting elevation and relevant outcomes in a series of case examples. Veterans with probable posttraumatic stress disorder completed experimental tasks including a written trauma narrative exercise and watching elevation-eliciting videos. Participants also completed baseline assessments, repeated measures of trauma-related cognitions, emotions, elevation, and saliva sample collection. Four cases were identified and reviewed: two positive responders (high elevation after videos) and two nonresponders (restricted elevation response). Positive responder cases reported decreased cognitions, emotions, and moral injury distress from after the trauma narrative to after elevation exercises, whereas nonresponders reported minimal to no changes. Positive responders also demonstrated decreases in cortisol, whereas nonresponders demonstrated increases in cortisol. Future work should examine whether elevation contributes to changes in biopsychosocial outcomes and identify individual factors that indicate who might benefit from elevation-based interventions.
MeSH term(s)	Humans ; Stress Disorders, Post-Traumatic/therapy ; Stress Disorders, Post-Traumatic/psychology ; Veterans/psychology ; Hydrocortisone ; Individuality ; Treatment Outcome ; Morals
Chemical Substances	Hydrocortisone (WI4X0X7BPJ)
Language	English
Publishing date	2023-09-29
Publishing country	United States
Document type	Journal Article
ZDB-ID	3020-x
ISSN	1539-736X ; 0022-3018
ISSN (online)	1539-736X
ISSN	0022-3018
DOI	10.1097/NMD.0000000000001725
Database	MEDical Literature Analysis and Retrieval System OnLINE

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