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  1. Book: Yang chi chi shu wen ta

    Ou-yang, Ying / Chang, Li

    (Chia tʻing fu yeh sheng chʻan tsʻung shu.)

    1984  

    Title variant Yangji jishu wenda
    Author's details Ou-yang Ying, Chang Li pien
    Series title Chia tʻing fu yeh sheng chʻan tsʻung shu.
    Keywords Chickens
    Language Chinese
    Dates of publication 1984-1985
    Size 5, 80 p. ;, 19 cm.
    Edition Ti 1 pan.
    Publisher Fu-chien kʻo hsüeh chi shu chʻu pan she ; Fu-chien sheng hsin hua shu tien fa hsing
    Publishing place Fu-chou
    Document type Book
    Database NAL-Catalogue (AGRICOLA)

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    Inter-library loan at ZB MED

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  2. Book ; Online: Creative Multilingualism : A Manifesto

    Kohl, Katrin / Dudrah, Rajinder / Gosler, Andrew / Graham, Suzanne / Maiden, Martin / Ouyang, Wen-chin / Reynolds, Matthew

    2020  

    Keywords Language ; Language: reference & general ; linguistics ; Bilingualism & multilingualism ; multilingualism ; human condition ; creative multilingualism ; language ; humanities ; social sciences ; natural sciences
    Size 1 electronic resource (334 pages)
    Publisher Open Book Publishers
    Document type Book ; Online
    Note English ; Open Access
    HBZ-ID HT021028719
    ISBN 9781783749348 ; 1783749342
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  3. Article ; Online: Lewis Acid-Catalyzed Tandem Reaction Strategy for the Synthesis of Dihydrophenalene-Fused Lactones.

    OuYang, Mingjing / OuYang, Jiewen / Dong, Yibin / Li, Jinwei / Yang, Wen

    The Journal of organic chemistry

    2024  

    Abstract: A Lewis acid-catalyzed tandem reaction strategy for the construction of a dihydrophenalene-lactone tetracyclic skeleton has been disclosed. Starting with 2-naphthol-tethered ketones and active methylene esters, the tandem reaction catalyzed by Sc(OTf) ...

    Abstract A Lewis acid-catalyzed tandem reaction strategy for the construction of a dihydrophenalene-lactone tetracyclic skeleton has been disclosed. Starting with 2-naphthol-tethered ketones and active methylene esters, the tandem reaction catalyzed by Sc(OTf)
    Language English
    Publishing date 2024-04-18
    Publishing country United States
    Document type Journal Article
    ZDB-ID 123490-0
    ISSN 1520-6904 ; 0022-3263
    ISSN (online) 1520-6904
    ISSN 0022-3263
    DOI 10.1021/acs.joc.4c00314
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4473: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (2.OG)
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  4. Article ; Online: Intramural twin pregnancy after in-vitro fertilization.

    Ouyang, Y / Xiao, J / Wang, Q / Wen, Y / Chen, H / Gong, F / Li, X

    Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology

    2024  

    Language English
    Publishing date 2024-03-05
    Publishing country England
    Document type Letter
    ZDB-ID 1073183-0
    ISSN 1469-0705 ; 0960-7692
    ISSN (online) 1469-0705
    ISSN 0960-7692
    DOI 10.1002/uog.27626
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3214: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (2.OG)
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  5. Book: Nung tsʻun chao chʻi chi shu wen ta

    Chʻen, Chen-kuo / Ou-yang, Ming-chu

    1983  

    Author's details Chʻen Chen-kuo, Ou-yang Ming-chu
    Keywords Biogas
    Language Chinese
    Size 3, 6, 64 p. :, ill. ;, 19 cm.
    Edition Ti 1 pan.
    Publisher Hu-pei kʻo hsüeh chi shu chʻu pan she ; Hu-pei sheng hsin hua shu tien fa hsing
    Publishing place Wu-han shih
    Document type Book
    Database NAL-Catalogue (AGRICOLA)

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  6. Article ; Online: Intermittent Hypobaric Hypoxia Ameliorates Autistic-Like Phenotypes in Mice.

    Pan, Yi-da / Zhang, Yuan / Zheng, Wen-Ying / Zhu, Min-Zhen / Li, Huan-Yu / Ouyang, Wen-Jie / Wen, Qin-Qing / Zhu, Xin-Hong

    The Journal of neuroscience : the official journal of the Society for Neuroscience

    2024  Volume 44, Issue 7

    Abstract: Autism spectrum disorder (ASD) is a neurodevelopmental condition characterized by persistent deficits in social communication and stereotyped behaviors. Although major advances in basic research on autism have been achieved in the past decade, and ... ...

    Abstract Autism spectrum disorder (ASD) is a neurodevelopmental condition characterized by persistent deficits in social communication and stereotyped behaviors. Although major advances in basic research on autism have been achieved in the past decade, and behavioral interventions can mitigate the difficulties that individuals with autism experience, little is known about the many fundamental issues of the interventions, and no specific medication has demonstrated efficiency for the core symptoms of ASD. Intermittent hypobaric hypoxia (IHH) is characterized by repeated exposure to lowered atmospheric pressure and oxygen levels, which triggers multiple physiological adaptations in the body. Here, using two mouse models of ASD, male
    MeSH term(s) Mice ; Male ; Animals ; Autistic Disorder/genetics ; Autistic Disorder/therapy ; Autism Spectrum Disorder/genetics ; Autism Spectrum Disorder/therapy ; Dorsal Raphe Nucleus ; Serotonergic Neurons/physiology ; Hypoxia ; Phenotype ; Fragile X Mental Retardation Protein
    Chemical Substances Fmr1 protein, mouse ; Fragile X Mental Retardation Protein (139135-51-6)
    Language English
    Publishing date 2024-02-14
    Publishing country United States
    Document type Journal Article
    ZDB-ID 604637-x
    ISSN 1529-2401 ; 0270-6474
    ISSN (online) 1529-2401
    ISSN 0270-6474
    DOI 10.1523/JNEUROSCI.1665-23.2023
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1668: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  7. Article ; Online: Experimental Decoding and Tuning Electronic Friction of Si Nanotip Sliding on Graphene.

    Li, Yutao / Wu, Bozhao / Ouyang, Wengen / Liu, Ze / Wang, Wen

    Nano letters

    2024  Volume 24, Issue 4, Page(s) 1130–1136

    Abstract: Due to the coupled contributions of adhesion and carrier to friction typically found in previous research, decoupling the electron-based dissipation is a long-standing challenge in tribology. In this study, by designing and integrating a graphene/ ...

    Abstract Due to the coupled contributions of adhesion and carrier to friction typically found in previous research, decoupling the electron-based dissipation is a long-standing challenge in tribology. In this study, by designing and integrating a graphene/
    Language English
    Publishing date 2024-01-22
    Publishing country United States
    Document type Journal Article
    ISSN 1530-6992
    ISSN (online) 1530-6992
    DOI 10.1021/acs.nanolett.3c03642
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Pleiotropic physiological functions of Piezo1 in human body and its effect on malignant behavior of tumors.

    Zhang, Yihan / Zou, Wen / Dou, Wenlei / Luo, Hongliang / Ouyang, Xi

    Frontiers in physiology

    2024  Volume 15, Page(s) 1377329

    Abstract: Mechanosensitive ion channel protein 1 (Piezo1) is a large homotrimeric membrane protein. Piezo1 has various effects and plays an important and irreplaceable role in the maintenance of human life activities and homeostasis of the internal environment. In ...

    Abstract Mechanosensitive ion channel protein 1 (Piezo1) is a large homotrimeric membrane protein. Piezo1 has various effects and plays an important and irreplaceable role in the maintenance of human life activities and homeostasis of the internal environment. In addition, recent studies have shown that Piezo1 plays a vital role in tumorigenesis, progression, malignancy and clinical prognosis. Piezo1 is involved in regulating the malignant behaviors of a variety of tumors, including cellular metabolic reprogramming, unlimited proliferation, inhibition of apoptosis, maintenance of stemness, angiogenesis, invasion and metastasis. Moreover, Piezo1 regulates tumor progression by affecting the recruitment, activation, and differentiation of multiple immune cells. Therefore, Piezo1 has excellent potential as an anti-tumor target. The article reviews the diverse physiological functions of Piezo1 in the human body and its major cellular pathways during disease development, and describes in detail the specific mechanisms by which Piezo1 affects the malignant behavior of tumors and its recent progress as a new target for tumor therapy, providing new perspectives for exploring more potential effects on physiological functions and its application in tumor therapy.
    Language English
    Publishing date 2024-04-16
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2564217-0
    ISSN 1664-042X
    ISSN 1664-042X
    DOI 10.3389/fphys.2024.1377329
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Metabolic disorders in prediabetes: From mechanisms to therapeutic management.

    Ping, Wen-Xin / Hu, Shan / Su, Jing-Qian / Ouyang, Song-Ying

    World journal of diabetes

    2024  Volume 15, Issue 3, Page(s) 361–377

    Abstract: Diabetes, one of the world's top ten diseases, is known for its high mortality and complication rates and low cure rate. Prediabetes precedes the onset of diabetes, during which effective treatment can reduce diabetes risk. Prediabetes risk factors ... ...

    Abstract Diabetes, one of the world's top ten diseases, is known for its high mortality and complication rates and low cure rate. Prediabetes precedes the onset of diabetes, during which effective treatment can reduce diabetes risk. Prediabetes risk factors include high-calorie and high-fat diets, sedentary lifestyles, and stress. Consequences may include considerable damage to vital organs, including the retina, liver, and kidneys. Interventions for treating prediabetes include a healthy lifestyle diet and pharmacological treatments. However, while these options are effective in the short term, they may fail due to the difficulty of long-term implementation. Medications may also be used to treat prediabetes. This review examines prediabetic treatments, particularly metformin, glucagon-like peptide-1 receptor agonists, sodium glucose cotransporter 2 inhibitors, vitamin D, and herbal medicines. Given the remarkable impact of prediabetes on the progression of diabetes mellitus, it is crucial to intervene promptly and effectively to regulate prediabetes. However, the current body of research on prediabetes is limited, and there is considerable confusion surrounding clinically relevant medications. This paper aims to provide a comprehensive summary of the pathogenesis of pre-diabetes mellitus and its associated therapeutic drugs. The ultimate goal is to facilitate the clinical utilization of medications and achieve efficient and timely control of diabetes mellitus.
    Language English
    Publishing date 2024-03-25
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2583471-X
    ISSN 1948-9358
    ISSN 1948-9358
    DOI 10.4239/wjd.v15.i3.361
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Inactivation of the TGF-β1/ALK5 axis enhances club cell function and alleviates lung tissue damage to ameliorate COPD progression through the MEK/ERK signaling pathway.

    Tian, Jing / Ouyang, Hui / Wu, Jie / Wen, Lu / Li, Xiaoping / Yang, Fangying / Yuan, Hao

    General physiology and biophysics

    2024  Volume 43, Issue 1, Page(s) 37–48

    Abstract: Chronic obstructive pulmonary disease (COPD) is a highly prevalent and fatal disease worldwide. The function of club cells, which are considered progenitor/stem cells of the bronchial epithelium, and their secreted protein CC16, have been proposed as ... ...

    Abstract Chronic obstructive pulmonary disease (COPD) is a highly prevalent and fatal disease worldwide. The function of club cells, which are considered progenitor/stem cells of the bronchial epithelium, and their secreted protein CC16, have been proposed as potential targets for COPD treatment. This study aimed to investigate the role of the TGF-β1/ALK5 signaling pathway in club cell function and COPD progression. C57BL/6J mice were divided into Normal group (exposed to fresh air) and COPD group (exposed to incremental cigarette smoke extract for 12 weeks). The COPD mice were further divided into COPD group, DMSO group, and LY2109761 group (injected with 150 mg/kg LY2109761, a TGF-β1 inhibitor). Tissue staining was used to assess lung damage, and the expression of CC16 was measured. The levels of inflammatory factors and DNA damage-related indicators were also measured. The involvement of the MEK/ERK signaling pathway was determined. COPD mice exhibited severe lung damage and impaired club cell function. Activation of the TGF-β1/ALK5 and MEK/ERK pathways were observed in COPD mice. However, administration of LY2109761 in COPD mice inactivated the TGF-β1/ALK5 and MEK/ERK pathways. Administration of LY2109761 also alleviated pulmonary fibrosis, downregulated the levels cleaved caspase-3, IL-4, IL-5, IL-13, IL-12, and IFN-γ, and limited the phosphorylation of Chk1. Moreover, LY2109761 enhanced CC16 expression and decreased lung cell apoptosis. Inactivation of the TGF-β1/ALK5 axis inhibits the MEK/ERK signaling pathway, enhances club cell function, and alleviates lung tissue damage. These findings suggest that TGF-β1 is a potential therapeutic target for COPD.
    MeSH term(s) Mice ; Animals ; MAP Kinase Signaling System ; Transforming Growth Factor beta1/metabolism ; Mice, Inbred C57BL ; Signal Transduction ; Lung ; Pulmonary Disease, Chronic Obstructive/drug therapy ; Pulmonary Disease, Chronic Obstructive/metabolism ; Mitogen-Activated Protein Kinase Kinases
    Chemical Substances Transforming Growth Factor beta1 ; Mitogen-Activated Protein Kinase Kinases (EC 2.7.12.2)
    Language English
    Publishing date 2024-01-24
    Publishing country Slovakia
    Document type Journal Article
    ZDB-ID 791184-1
    ISSN 0231-5882
    ISSN 0231-5882
    DOI 10.4149/gpb_2023034
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1874: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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