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  1. Article: Netherton Syndrome in a Mother and Her Two Children.

    DeMoss, Jack / Cooper, Leslie / Felts, Colby / Wittenberg, Gregory

    South Dakota medicine : the journal of the South Dakota State Medical Association

    2023  Volume 75, Issue 12, Page(s) 554–556

    Abstract: Netherton syndrome (NS) is a rare autosomal recessive condition caused by mutations in the serine peptidase inhibitor, Kazal type 5 (SPINK5) gene which encodes for a serine protease inhibitor, lymphoepithelial Kazal-typerelated inhibitor (LEKT1). NS is ... ...

    Abstract Netherton syndrome (NS) is a rare autosomal recessive condition caused by mutations in the serine peptidase inhibitor, Kazal type 5 (SPINK5) gene which encodes for a serine protease inhibitor, lymphoepithelial Kazal-typerelated inhibitor (LEKT1). NS is characterized by a triad of ichthyosiform erythroderma, trichorrhexis invaginata, and atopic diathesis with elevated IgE levels. The syndrome typically presents in infancy, where life-threatening complications are frequent, and evolves into a less severe condition with milder clinical symptoms in adulthood. This case report details the clinical history and genetic testing of a mother and two children with clinically symptomatic and genetically proven NS.
    MeSH term(s) Humans ; Child ; Female ; Netherton Syndrome/complications ; Netherton Syndrome/diagnosis ; Netherton Syndrome/genetics ; Mothers ; Serine Peptidase Inhibitor Kazal-Type 5/genetics ; Ichthyosiform Erythroderma, Congenital/genetics ; Mutation ; Serine Proteinase Inhibitors/genetics
    Chemical Substances Serine Peptidase Inhibitor Kazal-Type 5 ; Serine Proteinase Inhibitors
    Language English
    Publishing date 2023-03-10
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2278073-7
    ISSN 0038-3317
    ISSN 0038-3317
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Prolonged impacts of COVID-19-associated cystitis: A study on long-term consequences.

    Wittenberg, Sophie / Vercnocke, Jack / Chancellor, Michael / Dhar, Sorabh / Liaw, Aron / Lucas, Steven / Dhar, Nivedita

    World journal of clinical cases

    2023  Volume 11, Issue 33, Page(s) 7987–7993

    Abstract: Background: The Coronavirus Disease 2019 (COVID-19) caused by the severe acute respiratory syndrome coronavirus 2 virus is an international health concern with substantial morbidity and mortality. COVID-associated cystitis (CAC), presents as new onset ... ...

    Abstract Background: The Coronavirus Disease 2019 (COVID-19) caused by the severe acute respiratory syndrome coronavirus 2 virus is an international health concern with substantial morbidity and mortality. COVID-associated cystitis (CAC), presents as new onset or exacerbated urinary symptoms, resembling overactive bladder (OAB) symptoms.
    Aim: To examines the long-term outcomes of patients with CAC in the context of Long COVID.
    Methods: A cohort of 350 patients admitted to Detroit Hospitals with COVID-19 between May and December 2020, displaying CAC symptoms following discharge, was prospectively followed. Initial urologic evaluations occurred at 10-14 wk and were repeated at 21-28 mo post-discharge. Symptoms were managed conservatively, employing behavioral modifications and standard OAB medications. Participants completed surveys assessing urinary symptoms and quality of life (QoL) at both time points. The primary outcome was the Urology Care Foundation Overactive Bladder Assessment Tool.
    Results: 87% of the final cohort (
    Conclusion: This study presents the first long-term follow-up of adult patients with CAC, revealing a promising prognosis with conservative management measures in the context of Long COVID. These findings provide reassurance to patients regarding symptom resolution and underscore the need for further research into this evolving aspect of COVID-19's impact on urological health.
    Language English
    Publishing date 2023-11-24
    Publishing country United States
    Document type Journal Article
    ISSN 2307-8960
    ISSN 2307-8960
    DOI 10.12998/wjcc.v11.i33.7987
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Book: Primer of diagnostic imaging

    Weissleder, Ralph / Wittenberg, Jack / Harisinghani, Mukesh G.

    2003  

    Author's details Ralph Weissleder ; Jack Wittenberg ; Mukesh G. Harisinghani
    Keywords Diagnostic imaging
    Subject code 616.0754
    Language English
    Size XXII, 1049 S. : Ill., graph. Darst.
    Edition 3. ed.
    Publisher Mosby
    Publishing place St. Louis
    Publishing country United States
    Document type Book
    New title 4. Aufl. u.d.T. Primer of diagnostic imaging
    HBZ-ID HT013566908
    ISBN 0-323-02328-2 ; 978-0-323-02328-3
    Database Catalogue ZB MED Medicine, Health

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  4. Book: Kompendium der bildgebenden Diagnostik

    Weissleder, Ralph / Rieumont, Mark J. / Wittenberg, Jack

    2003  

    Title translation Primer of diagnostic imaging
    Author's details Ralph Weissleder, Mark J. Rieumont und Jack Wittenberg
    Keywords Bildgebendes Verfahren
    Subject Bildgebendes Diagnoseverfahren ; Diagnostik ; Bilddiagnostik ; Bildgebende Methode ; Medical Imaging ; Medizinische Bildgebung ; Bildgebende Diagnostik ; Bildgebende Verfahren ; Imaging
    Language German
    Size XVIII, 812 S. : Ill., graph. Darst.
    Publisher Springer
    Publishing place Wien u.a.
    Publishing country Austria
    Document type Book
    Note Aus dem Engl. übers.
    HBZ-ID HT013356225
    ISBN 3-211-83615-2 ; 978-3-211-83615-6
    Database Catalogue ZB MED Medicine, Health

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  5. Book: Primer of diagnostic imaging

    Weissleder, Ralph / Wittenberg, Jack

    1994  

    Title variant Diagnostic imaging
    Author's details Ralph Weissleder ; Jack Wittenberg
    Keywords Diagnostic Imaging ; Röntgendiagnostik
    Subject Röntgenuntersuchung ; Röntgendiagnose ; Röntgendiagnostisches Verfahren
    Language English
    Size XVIII, 862 S. : Ill., graph. Darst.
    Publisher Mosby
    Publishing place St. Louis u.a.
    Publishing country United States
    Document type Book
    HBZ-ID HT006489421
    ISBN 0-8151-9321-1 ; 978-0-8151-9321-0
    Database Catalogue ZB MED Medicine, Health

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  6. Book: Interventional radiology of the abdomen

    Ferrucci, Joseph T. / Wittenberg, Jack

    1981  

    Author's details JOSEPH T. FERRUCCI, JACK WITTENBERG
    Keywords Abdomen / radiography ; GASTROINTESTINAL DISEASES / RADIOTHERAPY ; RADIOTHERAPY / METHODS
    Size XVIII, 243 S. : ILL.
    Publisher Williams & Wilkins
    Publishing place BALTIMORE ; LONDON
    Document type Book
    HBZ-ID HT002555329
    ISBN 0-683-03174-0 ; 978-0-683-03174-4
    Database Catalogue ZB MED Medicine, Health

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  7. Book: CT of acute gastrointestinal disease

    Wittenberg, Jack

    (MGHecases)

    1999  

    Abstract: Producer) Provides a comprehensive review of common GI disorders encountered in ER practices. Uses compendium cases to illustrate normal variants. Illustrates pathology with clearly marked annotations and text descriptions. ...

    Title variant MGHecases in CT of acute gastrointestinal disease
    Institution Login Brothers Book Company
    Series title MGHecases
    Abstract (Producer) Provides a comprehensive review of common GI disorders encountered in ER practices. Uses compendium cases to illustrate normal variants. Illustrates pathology with clearly marked annotations and text descriptions.
    MeSH term(s) Gastrointestinal Diseases/diagnostic imaging ; Radiography ; Tomography, X-Ray Computed
    Language English
    Size 1 computer optical disc :, col. ;, 4 3/4 in.
    Publisher Login Brothers Book Co
    Publishing place Chicago, IL
    Document type Book
    Note Title from disc label.
    ISBN 9781929987061 ; 1929987064
    Database Catalogue of the US National Library of Medicine (NLM)

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  8. Article ; Online: Mitosis domain generalization in histopathology images - The MIDOG challenge.

    Aubreville, Marc / Stathonikos, Nikolas / Bertram, Christof A / Klopfleisch, Robert / Ter Hoeve, Natalie / Ciompi, Francesco / Wilm, Frauke / Marzahl, Christian / Donovan, Taryn A / Maier, Andreas / Breen, Jack / Ravikumar, Nishant / Chung, Youjin / Park, Jinah / Nateghi, Ramin / Pourakpour, Fattaneh / Fick, Rutger H J / Ben Hadj, Saima / Jahanifar, Mostafa /
    Shephard, Adam / Dexl, Jakob / Wittenberg, Thomas / Kondo, Satoshi / Lafarge, Maxime W / Koelzer, Viktor H / Liang, Jingtang / Wang, Yubo / Long, Xi / Liu, Jingxin / Razavi, Salar / Khademi, April / Yang, Sen / Wang, Xiyue / Erber, Ramona / Klang, Andrea / Lipnik, Karoline / Bolfa, Pompei / Dark, Michael J / Wasinger, Gabriel / Veta, Mitko / Breininger, Katharina

    Medical image analysis

    2022  Volume 84, Page(s) 102699

    Abstract: The density of mitotic figures (MF) within tumor tissue is known to be highly correlated with tumor proliferation and thus is an important marker in tumor grading. Recognition of MF by pathologists is subject to a strong inter-rater bias, limiting its ... ...

    Abstract The density of mitotic figures (MF) within tumor tissue is known to be highly correlated with tumor proliferation and thus is an important marker in tumor grading. Recognition of MF by pathologists is subject to a strong inter-rater bias, limiting its prognostic value. State-of-the-art deep learning methods can support experts but have been observed to strongly deteriorate when applied in a different clinical environment. The variability caused by using different whole slide scanners has been identified as one decisive component in the underlying domain shift. The goal of the MICCAI MIDOG 2021 challenge was the creation of scanner-agnostic MF detection algorithms. The challenge used a training set of 200 cases, split across four scanning systems. As test set, an additional 100 cases split across four scanning systems, including two previously unseen scanners, were provided. In this paper, we evaluate and compare the approaches that were submitted to the challenge and identify methodological factors contributing to better performance. The winning algorithm yielded an F
    MeSH term(s) Humans ; Mitosis ; Algorithms ; Neoplasm Grading ; Prognosis
    Language English
    Publishing date 2022-11-23
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 1356436-5
    ISSN 1361-8423 ; 1361-8431 ; 1361-8415
    ISSN (online) 1361-8423 ; 1361-8431
    ISSN 1361-8415
    DOI 10.1016/j.media.2022.102699
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Book: CT of acute gastrointestinal disease

    Wittenberg, Jack

    1991  

    Abstract: Producer) This course illustrates the application of CT to small-intestinal problems. The spectrum of problems resulting in small-bowel obstruction is increasingly recognized: adhesions, hemorrhage, tumor invasion, intussusception, volvulus. The ... ...

    Institution Radiological Society of North America
    Author's details the Radiological Society of North America
    Abstract (Producer) This course illustrates the application of CT to small-intestinal problems. The spectrum of problems resulting in small-bowel obstruction is increasingly recognized: adhesions, hemorrhage, tumor invasion, intussusception, volvulus. The multiple signs of bowel ischemia-such as mural wall thickening or gas, mesenteric vascular obstruction or gas, and gas in the portal venous tributaries, are accurately detected. Finally, intestinal perforation with abscess complicating inflammatory or neoplastic diseases is identified.
    MeSH term(s) Acute Disease ; Intestinal Diseases/diagnostic imaging ; Intestine, Small/diagnostic imaging ; Radiography ; Tomography, X-Ray Computed
    Language English
    Size 1 videocassette (39 min.) :, sd., b&w with col. ;, 1/2 in. +
    Publisher RSNA
    Publishing place Oak Brook, Ill
    Document type Book
    Note Approved for 1 1/2 credit hrs. in category 1.
    Accompanying material 1 leaflet.
    Database Catalogue of the US National Library of Medicine (NLM)

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  10. Article: Small bowel CT fat density target sign in chronic radiation enteritis.

    Chen, Steven / Harisinghani, Mukesh G / Wittenberg, Jack

    Australasian radiology

    2003  Volume 47, Issue 4, Page(s) 450–452

    Abstract: On CT, a thickened intestinal wall configured with a middle layer of low attenuation surrounded on each side by layers of higher attenuation has been termed the target sign. The presence of fat within the submucosal layer of the small intestine is a well- ...

    Abstract On CT, a thickened intestinal wall configured with a middle layer of low attenuation surrounded on each side by layers of higher attenuation has been termed the target sign. The presence of fat within the submucosal layer of the small intestine is a well-known manifestation of Crohn's disease, but has not been reported in other chronic intestinal diseases. We describe CT findings of fat density target sign in a patient with prior radiation.
    MeSH term(s) Adipose Tissue/diagnostic imaging ; Adipose Tissue/pathology ; Chronic Disease ; Enteritis/diagnostic imaging ; Enteritis/etiology ; Enteritis/pathology ; Humans ; Intestine, Small/diagnostic imaging ; Intestine, Small/pathology ; Male ; Middle Aged ; Radiotherapy/adverse effects ; Tomography, X-Ray Computed
    Language English
    Publishing date 2003-09-01
    Publishing country Australia
    Document type Case Reports ; Journal Article
    ZDB-ID 603966-2
    ISSN 0004-8461
    ISSN 0004-8461
    DOI 10.1046/j.1440-1673.2003.01219.x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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