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  1. Article ; Online: A Scoping Review of the Oral Health Status, Oral Health Behaviours and Interventions to Improve the Oral Health of Children and Young People in Care and Care Leavers.

    Booth, Joelle / Erwin, Jo / Burns, Lorna / Axford, Nick / Horrell, Jane / Wheat, Hannah / Witton, Robert / Shawe, Jill / Doughty, Janine / Kaddour, Sarah / Boswell, Skye / Devalia, Urshla / Nelder, Abigail / Paisi, Martha

    Dentistry journal

    2024  Volume 12, Issue 2

    Abstract: Background: Children and young people (CYP) in care experience poorer physical health and overall wellbeing in comparison to their peers. Despite this, relatively little is known about what their oral health needs and behaviours are. The aim of this ... ...

    Abstract Background: Children and young people (CYP) in care experience poorer physical health and overall wellbeing in comparison to their peers. Despite this, relatively little is known about what their oral health needs and behaviours are. The aim of this scoping review was to provide a global perspective on the oral health status and behaviours of CYP in care and care leavers. It also aimed to synthesise interventions that have been trialled in this population to improve oral health.
    Methods: Five databases were searched, Ovid Embase, Ovid MEDLINE, CINAHL (EBSCOhost), SocINDEX (EBSCOhost) and Dentistry and Oral Sciences Source (EBSCOhost), alongside grey literature sources up to January 2023. Eligibility criteria were studies that (i) reported on children and adolescents aged 25 years or younger who are currently in formal/informal foster or residential care and care leavers, (ii) pertained to oral health profile, behaviours or oral health promotion interventions (iii) and were published in the English language. Thematic analysis was used to develop the domains for oral health behaviours and interventions.
    Results: Seventy-one papers were included. Most papers were published from very high or medium Human Development Index countries. CYP in care were found to experience high levels of decay, dental trauma, periodontal disease and poorer oral health-related quality of life. Oral health behaviours included limited oral health self-care behaviours and a lack of oral health-based knowledge. The trialled interventions involved oral health education, supervised brushing and treatment or preventative dental care.
    Conclusions: This scoping review reveals that CYP in care experience poorer oral health in comparison to their peers. They are also less likely to carry out oral health self-care behaviours. This review highlights a scarcity of interventions to improve the oral health of this population and a paucity of evidence surrounding the oral health needs of care leavers.
    Language English
    Publishing date 2024-02-09
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2681351-8
    ISSN 2304-6767 ; 2304-6767
    ISSN (online) 2304-6767
    ISSN 2304-6767
    DOI 10.3390/dj12020038
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Access to Dental Care for Children and Young People in Care and Care Leavers: A Global Scoping Review.

    Erwin, Jo / Horrell, Jane / Wheat, Hannah / Axford, Nick / Burns, Lorna / Booth, Joelle / Witton, Robert / Shawe, Jill / Doughty, Janine / Kaddour, Sarah / Boswell, Skye / Devalia, Urshla / Nelder, Abigail / Paisi, Martha

    Dentistry journal

    2024  Volume 12, Issue 2

    Abstract: Aims: This scoping review aimed to explore three research questions: 1. What is the dental care access for children and young people (CYP) in care and care leavers? 2. What factors influence CYP in care and care leavers' access to dental care? 3. What ... ...

    Abstract Aims: This scoping review aimed to explore three research questions: 1. What is the dental care access for children and young people (CYP) in care and care leavers? 2. What factors influence CYP in care and care leavers' access to dental care? 3. What pathways have been developed to improve access to oral health care for CYP in care and care leavers?
    Methods: Five databases (Ovid MEDLINE, Ovid Embase, CINAHL, SocINDEX and Dentistry and Oral Sciences Source) and grey literature sources were systematically searched. Articles relating to CYP in care or care leavers aged 0-25 years old, published up to January 2023 were included. Abstracts, posters and publications not in the English language were excluded. The data relating to dental care access were analysed using thematic analysis.
    Results: The search identified 942 articles, of which 247 were excluded as duplicates. A review of the titles and abstracts yielded 149 studies. Thirty-eight were eligible for inclusion in the review: thirty-three peer-reviewed articles, one PhD thesis and four grey literature sources. All papers were published from very high or medium Human Development Index countries. The studies indicate that despite having higher treatment needs, CYP in care and care leavers experience greater difficulty in accessing dental services than those not care-experienced. Organisational, psycho-social and logistical factors influence their access to dental care. Their experience of dental care may be impacted by adverse childhood events. Pathways to dental care have been developed, but little is known of their impact on access. There are very few studies that include care leavers. The voices of care-experienced CYP are missing from dental access research.
    Conclusions: care-experienced CYP are disadvantaged in their access to dental care, and there are significant barriers to their treatment needs being met.
    Language English
    Publishing date 2024-02-08
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2681351-8
    ISSN 2304-6767 ; 2304-6767
    ISSN (online) 2304-6767
    ISSN 2304-6767
    DOI 10.3390/dj12020037
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Co-production of health and social science research with vulnerable children and young people: A rapid review.

    Erwin, Jo / Burns, Lorna / Devalia, Urshla / Witton, Robert / Shawe, Jill / Wheat, Hannah / Axford, Nick / Doughty, Janine / Kaddour, Sarah / Nelder, Abigail / Brocklehurst, Paul / Boswell, Skye / Paisi, Martha

    Health expectations : an international journal of public participation in health care and health policy

    2024  Volume 27, Issue 2, Page(s) e13991

    Abstract: Background: The term 'care-experienced' refers to anyone who is currently in care or has been in care at any stage in their life. A complex interplay of factors leads to care-experienced children and young people (CECYP) experiencing poorer oral health ... ...

    Abstract Background: The term 'care-experienced' refers to anyone who is currently in care or has been in care at any stage in their life. A complex interplay of factors leads to care-experienced children and young people (CECYP) experiencing poorer oral health and access to dental care than their peers. A rapid review of the co-production of health and social care research with vulnerable children and young people (CYP) was carried out to inform the development of a co-produced research project exploring the oral health behaviours and access to dental services of CECYP. Here, 'co-production' refers to the involvement of CYP in the planning or conduct of research with explicit roles in which they generate ideas, evidence and research outputs.
    Aim: To learn how to meaningfully involve vulnerable CYP in the co-production of health and social science research.
    Objectives: To identify: Different approaches to facilitating the engagement of vulnerable CYP in co-production of health and social science research; different activities carried out in such approaches, challenges to engaging vulnerable CYP in co-production of health and social science research and ways to overcome them and areas of best practice in relation to research co-production with vulnerable CYP.
    Search strategy: A rapid review of peer-reviewed articles was conducted in six databases (MEDLINE, Embase, SocINDEX, CINAHL, PsycINFO and Web of Science) and grey literature to identify studies that engaged vulnerable CYP in co-approaches to health and social research.
    Main results: Of 1394 documents identified in the search, 40 were included and analysed. A number of different approaches to co-production were used in the studies. The CYP was involved in a range of activities, chiefly the development of data collection tools, data collection and dissemination. Individual challenges for CYP and researchers, practical and institutional factors and ethical considerations impacted the success of co-production.
    Discussion and conclusion: Co-production of health and social science with vulnerable CYP presents challenges to researchers and CYP calling for all to demonstrate reflexivity and awareness of biases, strengths and limitations. Used appropriately and well, co-production offers benefits to researchers and CYP and can contribute to research that reflects the needs of vulnerable CYP. Adherence to the key principles of inclusion, safeguarding, respect and well-being facilitates this approach.
    Patient and public contribution: Members of our patient and public involvement and stakeholder groups contributed to the interpretation of the review findings. This manuscript was written together with a young care leaver, Skye Boswell, who is one of the authors. She contributed to the preparation of the manuscript, reviewing the findings and their interpretation.
    MeSH term(s) Adolescent ; Child ; Female ; Humans ; Research ; Social Sciences ; Health Services Research ; Vulnerable Populations
    Language English
    Publishing date 2024-02-25
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2119434-8
    ISSN 1369-7625 ; 1369-6513
    ISSN (online) 1369-7625
    ISSN 1369-6513
    DOI 10.1111/hex.13991
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Factors influencing oral health behaviours, access and delivery of dental care for autistic children and adolescents: A mixed-methods systematic review.

    Erwin, Jo / Paisi, Martha / Neill, Sarah / Burns, Lorna / Vassallo, Isaac / Nelder, Abigail / Facenfield, Jemma / Devalia, Urshla / Vassallo, Tara / Witton, Robert

    Health expectations : an international journal of public participation in health care and health policy

    2022  Volume 25, Issue 4, Page(s) 1269–1318

    Abstract: Background: Autistic children and young people (CYP) experience oral health (OH) inequalities. They are at high risk of dental disease and show significant levels of unmet need in relation to OH and access to dental care.: Aim: This study aimed to ... ...

    Abstract Background: Autistic children and young people (CYP) experience oral health (OH) inequalities. They are at high risk of dental disease and show significant levels of unmet need in relation to OH and access to dental care.
    Aim: This study aimed to gather evidence on the factors that influence OH behaviours, access to and delivery of dental care for autistic CYP.
    Design: This was a mixed-methods narrative systematic review.
    Data sources: Embase, Web of Science, Dentistry & Oral Sciences Source, MEDLINE, Psychinfo, Scopus, CINAHL, SocINDEX and grey literature were the data sources for this study.
    Review methods: A systematic search was conducted for qualitative, quantitative and mixed-methods research studies from countries with a High Development Index that related to OH behaviours, access to and delivery of dental care for autistic CYP. Results were analysed using narrative synthesis.
    Results: From 59 eligible studies, 9 themes were generated: (1) affordability and accessibility; (2) autism-related factors and cognitive or motor skill differences; (3) the dental environment; (4) managing CYP's behaviour; (5) responding and adapting to the needs of the autistic CYP and their parent/carer; (6) attitude of dental health professionals (DHPs) towards autistic CYP and their parents/carers; (7) knowledge of how to care for and support CYP's OH; (8) empowerment of parents/carers and collaboration with DHPs; and (9) communication and building rapport.
    Conclusion: The adoption of healthy OH behaviours and access to dental care by autistic CYP is impacted by a range of factors including those intrinsically related to a diagnosis of autism, for example, communication and those often associated with autism, for example, sensory sensitivities. Access to better OH and dental care can be facilitated by responding to the individual needs of autistic CYP through accommodation, education and adaptation. This necessitates greater awareness and knowledge of autism amongst DHPs and the provision of appropriate services. More methodologically robust intervention studies are needed to identify effective ways to support autistic CYP in achieving good OH and access to dental care.
    Patient and public contribution: The review protocol was developed with members of the project patient and public involvement group who provided the autistic voice, contributing to the interpretation of the review findings and writing of the manuscript.
    MeSH term(s) Adolescent ; Autistic Disorder ; Child ; Communication ; Delivery of Health Care ; Health Behavior ; Health Personnel ; Humans
    Language English
    Publishing date 2022-06-18
    Publishing country England
    Document type Journal Article ; Review ; Systematic Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 2119434-8
    ISSN 1369-7625 ; 1369-6513
    ISSN (online) 1369-7625
    ISSN 1369-6513
    DOI 10.1111/hex.13544
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Synergistic augmentation of rhythmic myogenic contractions of human stomach by arginine vasopressin and adrenaline: Implications for the induction of nausea.

    Makwana, Raj / Crawley, Ellie / Straface, Marilisa / Palmer, Alexandra / Gharibans, Armen / Devalia, Kalpana / Loy, John / O'Grady, Greg / Andrews, Paul L R / Sanger, Gareth J

    British journal of pharmacology

    2022  Volume 179, Issue 24, Page(s) 5305–5322

    Abstract: Background and purpose: Nausea is associated with the hormonal secretion of vasopressin and adrenaline, although their actions in inducing nausea is poorly understood. Here, we have investigated their actions on human stomach muscle.: Experimental ... ...

    Abstract Background and purpose: Nausea is associated with the hormonal secretion of vasopressin and adrenaline, although their actions in inducing nausea is poorly understood. Here, we have investigated their actions on human stomach muscle.
    Experimental approach: Muscle strips were suspended in tissue baths and neuronal-/non-neuronally-mediated contractions were measured. Custom software analysed eight motility parameters defining spontaneous phasic non-neuronally mediated contractions. Receptor distributions were assessed by qPCR and immunofluorescence.
    Key results: V<sub>1A</sub> receptors and α<sub>1</sub> -adrenoceptors were located on muscle as well as interstitial cells of Cajal (ICCs). Myogenic contractions of human proximal and distal stomach (respectively, 2.6 ± 0.1 and 2.7 ± 0.0 per minute; n = 44) were larger in the distal area (1.1 ± 0.1 and 5.0 ± 0.1 mN), developing relatively slowly (proximal) or rapidly (distal). Vasopressin caused tonic (proximal) or short-lived (distal) increases in muscle tone and increased myogenic contraction amplitude, frequency and rate (acting at V<sub>1A</sub> receptors; thresholds 10<sup>-11</sup> -10<sup>-10</sup>  M); by contrast, cholinergically mediated contractions were unaffected. Oxytocin acted similarly to vasopressin but less potently, at OT receptors). Adrenaline increased (10<sup>-10</sup> -10<sup>-5</sup>  M; α<sub>1</sub> -adrenoceptors) and decreased (≥10<sup>-6</sup>  M; β-adrenoceptors) muscle tone and enhanced/reduced myogenic contractions. Cholinergically mediated contractions were reduced (α<sub>2</sub> -adrenoceptors). Combined, vasopressin (10<sup>-9</sup>  M) and adrenaline (10<sup>-8</sup>  M) increased muscle tone and phasic myogenic activity in a synergistic manner.
    Conclusions and implications: Vasopressin and adrenaline increased human gastric tone and myogenic contraction amplitude, rate of contraction and frequency. In combination, their actions were further increased in a synergistic manner. Such activity may promote nausea.
    MeSH term(s) Humans ; Arginine Vasopressin/pharmacology ; Epinephrine/pharmacology ; Muscle Contraction ; Vasopressins ; Stomach ; Receptors, Adrenergic, beta ; Nausea
    Chemical Substances Arginine Vasopressin (113-79-1) ; Epinephrine (YKH834O4BH) ; Vasopressins (11000-17-2) ; Receptors, Adrenergic, beta
    Language English
    Publishing date 2022-09-22
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 80081-8
    ISSN 1476-5381 ; 0007-1188
    ISSN (online) 1476-5381
    ISSN 0007-1188
    DOI 10.1111/bph.15943
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Factors Influencing Oral Health Behaviours, Access and Provision of Dental Care for Autistic Children and Adolescents in Countries with a Very High Human Development Index: Protocol for a Mixed Methods Systematic Review.

    Erwin, Jo / Paisi, Martha / Witton, Robert / Neill, Sarah / Burns, Lorna / Vassallo, Isaac / Nelder, Abigail / Facenfield, Jemma / Devalia, Urshla / Vassallo, Tara

    International journal of environmental research and public health

    2021  Volume 18, Issue 23

    Abstract: Autistic children and adolescents are at high risk of dental disease and experience oral health inequalities. They consistently show high levels of unmet needs in relation to their oral health and access to dental care. There are no systematic reviews ... ...

    Abstract Autistic children and adolescents are at high risk of dental disease and experience oral health inequalities. They consistently show high levels of unmet needs in relation to their oral health and access to dental care. There are no systematic reviews that bring together the evidence on the factors that influence oral hygiene behaviours, and access to and provision of dental care for autistic children and adolescents. A systematic search will be carried out in eight international databases and in grey literature of qualitative, quantitative and mixed method research studies from countries with a High Development Index which relate to oral health behaviours, and access to and provision of dental care. Only studies where participants are autistic children and adolescents aged 19 years or under, parents/guardians/caregivers, support staff, or oral health care providers will be included. Quantitative and qualitative data will be synthesized together through data transformation using a convergent integrated approach. Thematic synthesis will be used to carry out an inductive analysis of the data. The findings from the systematic review which this protocol generates will be used in the development of an appropriate local clinic care pathway for autistic children/adolescents and to inform national policies and practices. Prospero registration: CRD 42021248764.
    MeSH term(s) Adolescent ; Autistic Disorder ; Child ; Dental Care ; Health Behavior ; Health Personnel ; Humans ; Oral Health ; Systematic Reviews as Topic
    Language English
    Publishing date 2021-11-24
    Publishing country Switzerland
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2175195-X
    ISSN 1660-4601 ; 1661-7827
    ISSN (online) 1660-4601
    ISSN 1661-7827
    DOI 10.3390/ijerph182312346
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Safety and Efficacy of Liraglutide, 3.0 mg, Once Daily vs Placebo in Patients With Poor Weight Loss Following Metabolic Surgery: The BARI-OPTIMISE Randomized Clinical Trial.

    Mok, Jessica / Adeleke, Mariam O / Brown, Adrian / Magee, Cormac G / Firman, Chloe / Makahamadze, Christwishes / Jassil, Friedrich C / Marvasti, Parastou / Carnemolla, Alisia / Devalia, Kalpana / Fakih, Naim / Elkalaawy, Mohamed / Pucci, Andrea / Jenkinson, Andrew / Adamo, Marco / Omar, Rumana Z / Batterham, Rachel L / Makaronidis, Janine

    JAMA surgery

    2023  Volume 158, Issue 10, Page(s) 1003–1011

    Abstract: Importance: Metabolic surgery leads to weight loss and improved health, but these outcomes are highly variable. Poor weight loss is associated with lower circulating levels of glucagon-like peptide-1 (GLP-1).: Objective: To assess the efficacy and ... ...

    Abstract Importance: Metabolic surgery leads to weight loss and improved health, but these outcomes are highly variable. Poor weight loss is associated with lower circulating levels of glucagon-like peptide-1 (GLP-1).
    Objective: To assess the efficacy and safety of the GLP-1 receptor agonist, liraglutide, 3.0 mg, on percentage body weight reduction in patients with poor weight loss and suboptimal GLP-1 response after metabolic surgery.
    Design, setting, and participants: The Evaluation of Liraglutide 3.0 mg in Patients With Poor Weight Loss and a Suboptimal Glucagon-Like Peptide-1 Response (BARI-OPTIMISE) randomized placebo-controlled trial recruited adult patients at least 1 year after metabolic surgery who had experienced 20% or less body weight loss from the day of surgery and a suboptimal nutrient-stimulated GLP-1 response from 2 hospitals in London, United Kingdom, between October 2018 and November 2019. Key exclusion criteria were type 1 diabetes; severe concomitant psychiatric, gastrointestinal, cardiac, kidney or metabolic disease; and use of insulin, GLP-1 receptor analogues, and medication that can affect weight. The study period was 24 weeks followed by a 4-week follow-up period. Last participant follow-up was completed in June 2020. All participants and clinical study personnel were blinded to treatment allocation. Of 154 assessed for eligibility, 70 met trial criteria and were included in the study, and 57 completed follow-up.
    Interventions: Liraglutide, 3.0 mg, once daily or placebo as an adjunct to lifestyle intervention with a 500-kcal daily energy deficit for 24 weeks, on a 1:1 allocation by computer-generated randomization sequence, stratified by surgery type (Roux-en-Y gastric bypass [RYGB] or sleeve gastrectomy [SG]) and type 2 diabetes status.
    Main outcome and measures: The primary outcome was change in percentage body weight from baseline to the end of the 24-week study period based on an intention-to-treat analysis. Participant safety was assessed through monitoring of biochemical parameters, including kidney and liver function, physical examination, and assessment for adverse events.
    Results: A total of 70 participants (mean [SD] age, 47.6 [10.7] years; 52 [74%] female) with a poor weight loss response following RYGB or SG were randomized to receive 3.0-mg liraglutide (n = 35) or placebo (n = 35). All participants received at least 1 dose of the trial drug. Eight participants discontinued treatment (4 per group), and 2 in the 3.0-mg liraglutide group and 1 in the placebo group were lost to follow-up. Due to COVID-19 restrictions, 3 participants in the 3.0-mg liraglutide group and 7 in the placebo group were unable to attend their final in-person assessment. Estimated change in mean (SD) percentage body weight from baseline to week 24 was -8.82 (4.94) with liraglutide, 3.0 mg (n = 31), vs -0.54 (3.32) with placebo (n = 26). The mean difference in percentage body weight change for liraglutide, 3.0 mg, vs placebo was -8.03 (95% CI, -10.39 to -5.66; P < .001). Adverse events, predominantly gastrointestinal, were more frequent with liraglutide, 3.0 mg (28 events [80%]), than placebo (20 events [57%]). There were no serious adverse events and no treatment-related deaths.
    Conclusion and relevance: These findings support the use of adjuvant liraglutide, 3.0 mg, for weight management in patients with poor weight loss and suboptimal GLP-1 response after metabolic surgery.
    Trial registration: ClinicalTrials.gov Identifier: NCT03341429.
    MeSH term(s) Adult ; Humans ; Female ; Middle Aged ; Male ; Liraglutide/therapeutic use ; Liraglutide/adverse effects ; Hypoglycemic Agents/therapeutic use ; Diabetes Mellitus, Type 2/drug therapy ; Diabetes Mellitus, Type 2/complications ; Glucagon-Like Peptide-1 Receptor/agonists ; Glucagon-Like Peptide-1 Receptor/therapeutic use ; Treatment Outcome ; Weight Loss ; Glucagon-Like Peptide 1/therapeutic use ; Bariatric Surgery ; Double-Blind Method
    Chemical Substances Liraglutide (839I73S42A) ; Hypoglycemic Agents ; Glucagon-Like Peptide-1 Receptor ; Glucagon-Like Peptide 1 (89750-14-1)
    Language English
    Publishing date 2023-07-26
    Publishing country United States
    Document type Randomized Controlled Trial ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2701841-6
    ISSN 2168-6262 ; 2168-6254
    ISSN (online) 2168-6262
    ISSN 2168-6254
    DOI 10.1001/jamasurg.2023.2930
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Impact of nutritional-behavioral and supervised exercise intervention following bariatric surgery: The BARI-LIFESTYLE randomized controlled trial.

    Jassil, Friedrich C / Carnemolla, Alisia / Kingett, Helen / Doyle, Jacqueline / Kirk, Amy / Lewis, Neville / Montagut, Gemma / Marvasti, Parastou / Boniface, David / Brown, Adrian / Chaiyasoot, Kusuma / Zakeri, Roxanna / Mok, Jessica / Devalia, Kalpana / Parmar, Chetan / Batterham, Rachel L

    Obesity (Silver Spring, Md.)

    2023  Volume 31, Issue 8, Page(s) 2031–2042

    Abstract: Objective: The study's aim was to investigate the impact of a 12-month adjunctive lifestyle intervention on weight loss and health outcomes after bariatric surgery.: Methods: A total of 153 participants (78.4% females; mean [SD], age 44.2 [10.6] ... ...

    Abstract Objective: The study's aim was to investigate the impact of a 12-month adjunctive lifestyle intervention on weight loss and health outcomes after bariatric surgery.
    Methods: A total of 153 participants (78.4% females; mean [SD], age 44.2 [10.6] years; BMI 42.4 [5.7] kg/m
    Results: Longitudinal analysis of the entire cohort showed significant reductions in body weight, fat mass, fat-free mass, and bone mineral density at the total hip, femoral neck, and lumbar spine (all p < 0.001). The 6-minute walk test, sit-to-stand test, health-related quality of life, and depressive symptomatology improved significantly (all p < 0.001). The time spent in moderate-to-vigorous physical activity and sedentary behavior remained the same as before surgery (both p > 0.05). There was no significant difference in the primary outcome between the intervention versus control (20.4% vs. 21.2%; mean difference = -0.8%; 95% CI: -2.8 to 1.1; p > 0.05) and no between-group differences in secondary outcomes.
    Conclusions: An adjunctive lifestyle program implemented immediately after surgery had no favorable impact upon weight loss and health outcomes.
    MeSH term(s) Female ; Humans ; Adult ; Male ; Quality of Life ; Life Style ; Bariatric Surgery ; Weight Loss ; Exercise Therapy
    Language English
    Publishing date 2023-07-06
    Publishing country United States
    Document type Randomized Controlled Trial ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2230457-5
    ISSN 1930-739X ; 1071-7323 ; 1930-7381
    ISSN (online) 1930-739X
    ISSN 1071-7323 ; 1930-7381
    DOI 10.1002/oby.23814
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Early results of a novel technique: Hindfoot fusion in talus osteonecrosis prior to ankle arthroplasty: A case series.

    Devalia, Kailash L / Ramaskandhan, Jayasree / Muthumayandi, Karthikeyan / Siddique, Malik

    Foot (Edinburgh, Scotland)

    2015  Volume 25, Issue 4, Page(s) 200–205

    Abstract: Background: The purpose of this study was to evaluate the clinical outcome of a two staged approach of subtalar arthrodesis followed by TAR for patients with ankle arthritis and AVN talus.: Methods: Out of total 210 TARs performed at our institute; 7 ...

    Abstract Background: The purpose of this study was to evaluate the clinical outcome of a two staged approach of subtalar arthrodesis followed by TAR for patients with ankle arthritis and AVN talus.
    Methods: Out of total 210 TARs performed at our institute; 7 patients underwent a two staged procedure between 2006 and 2010. All patients had over 3 years of follow up (except one). The clinical results were assessed using AOFAS, WOMAC, SF-36 and patient satisfaction scores.
    Results: The mean follow up was 3 years. There was significant improvement in AOFAS and WOMAC (pain and stiffness) from pre-op to 3 years post-op (P<0.05). SF 36 scores improved from pre-op to 3 years post-op for 6/8 domains. 5 patients were satisfied at 3 years for overall surgical outcomes, 4 were satisfied with pain relief. Radiological signs of talar subsidence were noted in 2 patients at year 1. This did not progress at 3 years and did not deteriorate clinical outcome.
    Conclusion: We recommend our two staged approach to deal with this difficult clinical problem. We believe this approach is safe for TAR surgery where talar vascularity and bone quality is questionable leading to reduced talar subsidence, ischaemic pain and improvement in longevity of TAR.
    Level of evidence: Evidence IV (Retrospective case series).
    MeSH term(s) Aged ; Ankle/surgery ; Arthrodesis/methods ; Arthroplasty, Replacement, Ankle ; Female ; Follow-Up Studies ; Humans ; Magnetic Resonance Imaging ; Male ; Middle Aged ; Osteonecrosis/diagnosis ; Osteonecrosis/surgery ; Preoperative Care/methods ; Retrospective Studies ; Talus/surgery ; Time Factors
    Language English
    Publishing date 2015-12
    Publishing country Scotland
    Document type Case Reports ; Journal Article
    ZDB-ID 1070358-5
    ISSN 1532-2963 ; 0958-2592
    ISSN (online) 1532-2963
    ISSN 0958-2592
    DOI 10.1016/j.foot.2015.07.001
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  10. Article ; Online: Patients' views and experiences of live supervised tele-exercise classes following bariatric surgery during the COVID-19 pandemic: The BARI-LIFESTYLE qualitative study.

    Jassil, Friedrich C / Richards, Rebecca / Carnemolla, Alisia / Lewis, Neville / Montagut-Pino, Gemma / Kingett, Helen / Doyle, Jacqueline / Kirk, Amy / Brown, Adrian / Chaiyasoot, Kusuma / Devalia, Kalpana / Parmar, Chetan / Batterham, Rachel L

    Clinical obesity

    2021  Volume 12, Issue 2, Page(s) e12499

    Abstract: The BARI-LIFESTYLE trial is a randomized controlled trial evaluating the efficacy of a post-surgery nutritional and behavioural tele-counselling, and supervised exercise programme to maximize the health benefits of bariatric surgery. Due to the ... ...

    Abstract The BARI-LIFESTYLE trial is a randomized controlled trial evaluating the efficacy of a post-surgery nutritional and behavioural tele-counselling, and supervised exercise programme to maximize the health benefits of bariatric surgery. Due to the coronavirus disease 2019 (COVID-19) pandemic, the in-person supervised exercise component had to be converted to remote tele-exercise. However, patients' acceptability of this method of exercise provision is unknown. Between 3 and 6 months following bariatric surgery, 13 adults participated in weekly, structured, 60-min supervised exercise classes delivered via Zoom by a trained exercise therapist. A total of 12 participants (n = 8 female), with a mean age of 46.3 (range 33-63) years, who had undergone either sleeve gastrectomy (n = 8) or Roux-en-Y gastric bypass (n = 4) surgery, participated in one-to-one semi-structured interviews following the tele-exercise classes. Interviews were audio-recorded, transcribed verbatim and analysed using thematic analysis. Participants described how the tele-exercise classes helped them to cope with the changes to their lives brought about by the COVID-19 pandemic. Participants found the tele-exercise schedule, content and intensity to be acceptable, and were satisfied with the privacy, security and safety of the technology and classes. Professional supervision and guidance from an exercise therapist were described as central to the tele-exercise provision. Importantly, participation in the tele-exercise provided physical, emotional and social benefits. Few participants reported barriers to participation. Overall, the tele-exercise classes were deemed acceptable and compared favourably to in-person exercise classes.
    MeSH term(s) Adult ; Bariatric Surgery ; COVID-19/epidemiology ; Female ; Humans ; Life Style ; Middle Aged ; Pandemics ; SARS-CoV-2
    Language English
    Publishing date 2021-11-28
    Publishing country England
    Document type Journal Article ; Randomized Controlled Trial
    ZDB-ID 2625816-X
    ISSN 1758-8111 ; 1758-8103
    ISSN (online) 1758-8111
    ISSN 1758-8103
    DOI 10.1111/cob.12499
    Database MEDical Literature Analysis and Retrieval System OnLINE

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