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Article ; Online: R

Prasad, Durga / Mogurampelly, Santosh / Chaudhari, Sachin R

RSC advances

2020 Volume 10, Issue 4, Page(s) 2303–2312

Abstract: Enantiomers have significant importance in pharmaceuticals, biology and modern chemistry and therefore distinguishing and quantifying the enantiomeric forms is of utmost importance. Herein, we propose diphenyl-3,3'-biphenanthryl-4,4'-diyl phosphate ( ...

Abstract	Enantiomers have significant importance in pharmaceuticals, biology and modern chemistry and therefore distinguishing and quantifying the enantiomeric forms is of utmost importance. Herein, we propose diphenyl-3,3'-biphenanthryl-4,4'-diyl phosphate (
Language	English
Publishing date	2020-01-13
Publishing country	England
Document type	Journal Article
ISSN	2046-2069
ISSN (online)	2046-2069
DOI	10.1039/c9ra07803g
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Article: Kannada Translation and Validation of the ESAS-r Renal for Symptom Burden Survey in Patients with End-Stage Kidney Disease.

Naik, Bharathi / Nagaraju, Shankar Prasad / Guddattu, Vasudeva / Salins, Naveen / Prabhu, Ravindra / Damani, Anuja / Naik, Prathvi / Rao, Krithika S / Rao, Indu Ramachandra / Singhai, Pankaj

Indian journal of palliative care

2023 Volume 29, Issue 2, Page(s) 195–199

Abstract: ... of the Edmonton Symptom Assessment System Revised Renal (ESAS-r: Renal) in Kannada-speaking ESKD patients ... Materials and methods: ESAS-r: Renal English version was translated into Kannada using the forward and ... for appropriateness and relevance. The ESAS-r: Renal Kannada version was validated by administering this tool to 45 ...

Abstract	Objectives: End-stage kidney disease (ESKD) is a life-limiting illness that leads to significant health-related suffering for the patients and their caregivers. Moreover, disease-directed options such as dialysis and renal transplant might not be universally accessible. Inadequate assessment and management of symptoms often lead to diminished quality of life. For evaluating symptoms and their associated distress, various tools have been identified. However, these are not available for the native Kannada-speaking population for assessing ESKD symptom burden. In this study, we determined the reliability and validity of the Edmonton Symptom Assessment System Revised Renal (ESAS-r: Renal) in Kannada-speaking ESKD patients. Materials and methods: ESAS-r: Renal English version was translated into Kannada using the forward and backward method. The translated version was endorsed by Nephrology, Palliative care, Dialysis technology and Nursing experts. As a pilot study, 12 ESKD patients evaluated the content of the questionnaires for appropriateness and relevance. The ESAS-r: Renal Kannada version was validated by administering this tool to 45 patients twice a fortnight. Result: The translated ESAS-r: Renal Kannada version questionnaire had an acceptable face and content validity. Experts' opinion was assessed by content validity ratio (CVR), and the value of CVR of ESAS-r: Renal Kannada version was-'1'-. Internal consistency of the tool was assessed among Kannada-speaking ESKD patients; its Cronbach's α was 0.785, and test-retest validity was 0.896. Conclusion: The validated Kannada version of ESAS-r: Renal was reliable and valid for assessing symptom burden in ESKD patients.
Language	English
Publishing date	2023-05-30
Publishing country	United States
Document type	Journal Article
ISSN	0973-1075
ISSN	0973-1075
DOI	10.25259/IJPC_216_2022
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Article ; Online: Sesbanimide R, a Novel Cytotoxic Polyketide Produced by Magnetotactic Bacteria.

Awal, Ram Prasad / Haack, Patrick A / Bader, Chantal D / Riese, Cornelius N / Schüler, Dirk / Müller, Rolf

mBio

2021 Volume 12, Issue 3

Abstract: Genomic information from various magnetotactic bacteria suggested that besides their common ability to form magnetosomes, they potentially also represent a source of bioactive natural products. By using targeted deletion and transcriptional activation, ... ...

Abstract	Genomic information from various magnetotactic bacteria suggested that besides their common ability to form magnetosomes, they potentially also represent a source of bioactive natural products. By using targeted deletion and transcriptional activation, we connected a large biosynthetic gene cluster (BGC) of the
MeSH term(s)	Bacterial Proteins/biosynthesis ; Bacterial Proteins/classification ; Bacterial Proteins/metabolism ; Biological Products/metabolism ; Biosynthetic Pathways ; Magnetospirillum/metabolism ; Phylogeny ; Polyketides/metabolism ; Secondary Metabolism
Chemical Substances	Bacterial Proteins ; Biological Products ; Polyketides
Language	English
Publishing date	2021-05-18
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2557172-2
ISSN	2150-7511 ; 2161-2129
ISSN (online)	2150-7511
ISSN	2161-2129
DOI	10.1128/mBio.00591-21
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Article ; Online: Registration of grain sorghum seed (A/B) and pollinator (R) parent lines for chilling and drought tolerance

Perumal, Ramasamy / Tesso, Tesfaye T. / Jagadish, S. V. Krishna / Kumar, Vipan / Aiken, Robert M. / Bean, Scott R. / Smolensky, Dmitriy / Peiris, K. H. Shantha / Prasad, P. V. Vara / Little, Christopher R.

Journal of Plant Registrations. 2023 May, v. 17, no. 2 p.435-445

2023

Abstract: Four sorghum [Sorghum bicolor (L.) Moench] seed parents, male sterile A and four male fertile B maintainer lines (KS148A [Reg. no. PL‐321, PI 701488], KS148B [Reg. no. PL‐322, PI 701489], KS149A [Reg. no. PL‐323, PI 701490], KS149B [Reg. no. PL‐324, PI ... ...

Abstract	Four sorghum [Sorghum bicolor (L.) Moench] seed parents, male sterile A and four male fertile B maintainer lines (KS148A [Reg. no. PL‐321, PI 701488], KS148B [Reg. no. PL‐322, PI 701489], KS149A [Reg. no. PL‐323, PI 701490], KS149B [Reg. no. PL‐324, PI 701491], KS150A [Reg. no. PL‐325, PI 701492], KS150B [Reg. no. PL‐326, PI 701493], KS151A [Reg. no. PL‐327, PI 701494], KS151B [Reg. no. PL‐328, PI 701495]), and six pollinator parents [KS152R (Reg. no. PL‐329, PI 701496), KS153R (Reg. no. PL‐330, PI 701497), KS154R (Reg. no. PL‐331, PI 701498), KS155R (Reg. no. PL‐332, PI 701499), KS156R (Reg. no. PL‐333, PI 701500), and KS157R (Reg. no. PL‐334, PI 701501) from the Kansas State University, Agricultural Research Center, Hays, KS, were approved for release by the Kansas State University in July 2021. These 10 lines were from different populations and were developed through recurrent selection (random mating) followed by pedigree and backcross breeding methods between the selected germplasms (PI 574562, PI 550610, PI 574599, PI 574560, PI 550607, and IS 1269C), adapted breeding lines and different genetic male sterile ms3 lines (KP 8B, N310B, B06‐41701‐167, B9614, BHF14, BH8606‐6) in different combinations. Parent lines KS148A&B, KS149A&B, KS152R, and KS153R are tolerant to chilling stress and KS150A&B, KS151A&B, KS154R, KS155R, KS156R, and KS157R are tolerant to drought stress and are recommended to develop hybrids respectively for early (end of April to first week of May) and regular (end of May to first week of June) planting for the central Great Plains. Preliminary screening of all 10 lines showed tolerance to nine postemergence herbicides. These 10 parent lines are early to medium maturity, three‐dwarf (dw1, Dw2, dw3, dw4) in height, photoperiod‐insensitive, and possess unique combinations of plant and seed color. All 10 parent lines are tannin free with acceptable grain quality, short peduncle length, compact or semi‐compact panicles, and combining ability for yield and standability.
Keywords	Sorghum bicolor ; agricultural research ; backcrossing ; drought tolerance ; germplasm ; grain quality ; grain sorghum ; males ; pedigree ; peduncle ; pollinators ; recurrent selection ; seed color ; water stress ; Kansas
Language	English
Dates of publication	2023-05
Size	p. 435-445.
Publishing place	John Wiley & Sons, Ltd
Document type	Article ; Online
Note	JOURNAL ARTICLE
ZDB-ID	2381569-3
ISSN	1940-3496 ; 1936-5209
ISSN (online)	1940-3496
ISSN	1936-5209
DOI	10.1002/plr2.20213
Database	NAL-Catalogue (AGRICOLA)

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Article: Registration of Six Grain Sorghum Pollinator (R) Lines

Perumal, R. / Tesso, T. / Kofoid, K. D. / Aiken, R. M. / Prasad, P. V. V. / Bean, S. R. / Wilson, J. D. / Herald, T. J. / Little, C. R.

Journal of plant registrations. 2019 Jan., v. 13, no. 1

2019

Abstract: ... University Agricultural Research Center, Hays, KS, in August 2017. The released pollinator (R) lines were ... breeders. All six R lines can be used as male parents to develop potential high‐yielding drought‐tolerant ...

Abstract	Six sorghum [Sorghum bicolor (L.) Moench] pollinators—KS142R (Reg. No. PL‐307, PI 687867), KS143R (Reg. No. PL‐308, PI 687868), KS144R (Reg. No. PL‐309, PI 687869), KS145R (Reg. No. PL‐310, PI 687870), KS146R (Reg. No. PL‐311, PI 687871), and KS147R (Reg. No. PL‐312, PI 687872)—were developed from random mating using a recurrent selection followed by pedigree methods and released by the Kansas State University Agricultural Research Center, Hays, KS, in August 2017. The released pollinator (R) lines were evaluated in hybrid combinations over several environments for agronomic and yield traits. These lines were selected for release based on their agronomic desirability and unique combination of drought and stalk rots tolerance, grain quality traits, and high yield potential in hybrid combinations of importance to sorghum breeders. All six R lines can be used as male parents to develop potential high‐yielding drought‐tolerant hybrids with seed parents having A1 cytoplasmic male sterility background.
Keywords	Sorghum bicolor ; agricultural research ; cytoplasmic male sterility ; drought ; drought tolerance ; grain quality ; grain sorghum ; hybrids ; males ; pedigree ; pollinators ; recurrent selection ; Kansas
Language	English
Dates of publication	2019-01
Size	p. 113-117.
Publishing place	The Crop Science Society of America, Inc.
Document type	Article
Note	JOURNAL ARTICLE ; epub
ZDB-ID	2381569-3
ISSN	1940-3496 ; 1936-5209
ISSN (online)	1940-3496
ISSN	1936-5209
DOI	10.3198/jpr2017.12.0087crp
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: A hyperspectral R based leaf area index estimator: model development and implementation using AVIRIS-NG

Singh, Prachi / Srivastava, Prashant K. / Mall, R. K. / Bhattacharya, Bimal K. / Prasad, Rajendra

Geocarto International. 2022 Dec. 13, v. 37, no. 26 p.12792-12809

2022

Abstract: ... estimator” developed using the HRS data on an open-source R platform. The generic model structure provides ... The analysis indicates that during tillering stage the performance was found best during calibration (r = 0.66 ... RMSE =0.40, and Bias =-0.80) and validation (r = 0.98, RMSE =0.20, and Bias =0.12) in comparison ...

Abstract	Hyperspectral Remote Sensing (HRS) data is vital for crop growth monitoring due to availability of contiguous bands. This research work provides a new novel crop estimator model given the name “Crop Stage estimator” developed using the HRS data on an open-source R platform. The generic model structure provides an easy way to test and modify the importance of crop parameter namely Leaf Area Index to deduce crop growth stages of winter wheat (Triticum aestivum L.) particularly during –heading, tillering and booting. Further, to know the LAI variations at different agriculture sites, the best model was implemented using the AVIRIS-NG (Airborne Visible Near-Infrared Imaging Spectrometer - Next Generation) hyperspectral datasets. The analysis indicates that during tillering stage the performance was found best during calibration (r = 0.66, RMSE =0.40, and Bias =-0.80) and validation (r = 0.98, RMSE =0.20, and Bias =0.12) in comparison to the ground measurements.
Keywords	Triticum aestivum ; calibration ; data collection ; leaf area index ; models ; spectrometers ; tillering ; winter wheat ; Crop stage ; LAI ; simulation ; spectroradiometer ; hyperspectral ; AVIRIS-NG
Language	English
Dates of publication	2022-1213
Size	p. 12792-12809.
Publishing place	Taylor & Francis
Document type	Article ; Online
ISSN	1752-0762
DOI	10.1080/10106049.2022.2071476
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Prevalence of myopia and its risk factors in rural school children in North India: the North India myopia rural study (NIM-R Study).

Saxena, Rohit / Gupta, Vivek / Prasad, Priyanka / Bhardwaj, Amit / Vashist, Praveen

Eye (London, England)

2021 Volume 36, Issue 10, Page(s) 2000–2005

Abstract: Background: To assess the prevalence of myopia and its risk factors in rural school children.: Methods: Children in classes 4-7 of eight randomly selected schools (five government and three private) in rural Haryana, with unaided vision <6/9.5 were ... ...

Abstract	Background: To assess the prevalence of myopia and its risk factors in rural school children. Methods: Children in classes 4-7 of eight randomly selected schools (five government and three private) in rural Haryana, with unaided vision <6/9.5 were screened, their cycloplegic refraction is done, myopes were identified. A questionnaire-based assessment of risk factors was done for myopes and compared with 10% of randomly selected children with normal vision (controls). The prevalence of myopia and its association with risk factors were assessed. Results: Children screened were 1486 (89.5% coverage). The mean age of children was 11.2 ± 1.5 years with 861 (57.9%) boys. Prevalence of myopia was 6.4% (95% Confidence intervals [CI]: 5.2%, 7.8%). Prevalence was higher among private schools (10.1%) compared to government schools (1.4%) (p < 0.001), and among girls 7.2% (45/625) compared to boys 5.8% (50/861) (p = 0.2786). The mean spherical equivalent refractive error was -1.61D ± 1.32D. The prevalence of high myopia was 1.1% (1/95). There was a 75% unmet need for spectacles. Studying in private school was positively associated with myopia as per our multivariate analysis (p = 0.016). An inverse association was found for time spent outdoors (p = 0.009). Watching television, indoor time, screen time, age, or gender were not found to be statistically significant as risk factors. Conclusion: The prevalence of myopia is increasing among children of rural areas, especially those in private schools with a strong inverse association with time spent outdoors. Regular screening, lifestyle modification and awareness about modifiable risk factors are essential.
MeSH term(s)	Child ; Female ; Humans ; India/epidemiology ; Male ; Mydriatics ; Myopia/epidemiology ; Prevalence ; Refraction, Ocular ; Risk Factors
Chemical Substances	Mydriatics
Language	English
Publishing date	2021-10-14
Publishing country	England
Document type	Journal Article
ZDB-ID	91001-6
ISSN	1476-5454 ; 0950-222X
ISSN (online)	1476-5454
ISSN	0950-222X
DOI	10.1038/s41433-021-01797-3
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Article: Effect of Moisture Conservation Practices on Growth and Yield of Pearlmillet [Pennisetum glaucum (L.) R. Br. emend Stuntz] Hybrids

Choudhary, Sheeshpal / Yadav, L. R. / Shivran, A. C. / Choudhary, Meena / Bana, Ramesh Chand / Lal, Babu / Daroga, Shiv Prasad

Legume research

2022 Volume 45, Issue 8, Page(s) 1000

Document type	Article
ZDB-ID	407856-1
ISSN	0250-5371
Database	Current Contents Nutrition, Environment, Agriculture

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Article ; Online: Structural stability of R-state conformation of carbonmonoxyl sickle and normal hemoglobin dimer.

Powrel, Jhulan / Koirala, Rajendra Prasad / Adhikari, Narayan Prasad

Journal of biomolecular structure & dynamics

2022 Volume 41, Issue 19, Page(s) 9957–9966

Abstract: ... In this work, we have studied the binding mechanism between two chains in the dimer structure of the R-state ...

Abstract	A mutation at the sixth residue, glutamic acid to valine, in beta chain of hemoglobin distorts the entire shape of hemoglobin into a sickle shape. The investigation of the binding mechanisms of different chains of hemoglobin under the mutated condition can give an understanding of the molecular distortion. In this work, we have studied the binding mechanism between two chains in the dimer structure of the R-state conformation of carbonmonoxyl sickle hemoglobin and is compared with that of normal hemoglobin by using molecular dynamics simulations. The binding strength between
MeSH term(s)	Humans ; Hemoglobins/chemistry ; Protein Conformation ; Molecular Dynamics Simulation ; Hemoglobin, Sickle ; Anemia, Sickle Cell/metabolism
Chemical Substances	Hemoglobins ; Hemoglobin, Sickle
Language	English
Publishing date	2022-12-06
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	49157-3
ISSN	1538-0254 ; 0739-1102
ISSN (online)	1538-0254
ISSN	0739-1102
DOI	10.1080/07391102.2022.2150890
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Article ; Online: Clinical benefit of R-CHOP without splenectomy in stage I primary splenic diffuse large B-cell lymphoma.

Rajendran, Tara / Kini, Jyoti Ramanath / Abna, Aysha / Prasad, Krishna

BMJ case reports

2022 Volume 15, Issue 1

Abstract: ... confirmed the diagnosis of PS-DLBCL. He was managed with six cycles of R-CHOP (rituximab, cyclophosphamide ...

Abstract	Primary splenic diffuse large B-cell lymphoma (PS-DLBCL) is a relatively rare malignancy, and there are no optimal approaches for diagnosis and management. There are less invasive splenic biopsies that effectively obviate diagnostic and elective splenectomies. We report a man in his 50s with 2-day history of pain in the abdomen and who was found to have a splenic mass on PET-CT. A CT-guided core needle splenic biopsy confirmed the diagnosis of PS-DLBCL. He was managed with six cycles of R-CHOP (rituximab, cyclophosphamide, doxorubicin, vincristine, prednisone) alone, without splenectomy. The patient attained complete remission, and he is disease free at 6 years of follow-up.
MeSH term(s)	Antineoplastic Combined Chemotherapy Protocols/therapeutic use ; Cyclophosphamide/therapeutic use ; Doxorubicin/therapeutic use ; Humans ; Lymphoma, Large B-Cell, Diffuse/diagnosis ; Lymphoma, Large B-Cell, Diffuse/drug therapy ; Lymphoma, Large B-Cell, Diffuse/surgery ; Male ; Middle Aged ; Positron Emission Tomography Computed Tomography ; Prednisone/therapeutic use ; Rituximab/therapeutic use ; Splenectomy ; Vincristine/therapeutic use
Chemical Substances	R-CHOP protocol ; Rituximab (4F4X42SYQ6) ; Vincristine (5J49Q6B70F) ; Doxorubicin (80168379AG) ; Cyclophosphamide (8N3DW7272P) ; Prednisone (VB0R961HZT)
Language	English
Publishing date	2022-01-04
Publishing country	England
Document type	Case Reports ; Journal Article
ISSN	1757-790X
ISSN (online)	1757-790X
DOI	10.1136/bcr-2021-246610
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