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  1. Article ; Online: Corrigendum to 'Distinct gene dysregulation patterns herald precision medicine potentiality in systemic lupus erythematosus' [J. Autoimmun. 136 (April 2023) 103025].

    Lindblom, Julius / Toro-Domínguez, Daniel / Carnero-Montoro, Elena / Beretta, Lorenzo / Borghi, Maria Orietta / Castillo, Jessica / Enman, Yvonne / Mohan, Chandra / Alarcón-Riquelme, Marta E / Barturen, Guillermo / Parodis, Ioannis

    Journal of autoimmunity

    2023  , Page(s) 103052

    Language English
    Publishing date 2023-05-02
    Publishing country England
    Document type Published Erratum
    ZDB-ID 639452-8
    ISSN 1095-9157 ; 0896-8411
    ISSN (online) 1095-9157
    ISSN 0896-8411
    DOI 10.1016/j.jaut.2023.103052
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    Zs.A 2368: Show issues Location:
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  2. Article ; Online: Do social connections impact the health and functioning of persons with dementia?

    Montoro-Rodriguez, Julian / Hayslip, Bert

    International psychogeriatrics

    2024  Volume 36, Issue 2, Page(s) 79–82

    MeSH term(s) Humans ; Dementia
    Language English
    Publishing date 2024-01-17
    Publishing country England
    Document type Journal Article
    ZDB-ID 1038825-4
    ISSN 1741-203X ; 1041-6102
    ISSN (online) 1741-203X
    ISSN 1041-6102
    DOI 10.1017/S1041610224000036
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    Zs.A 2621: Show issues Location:
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  3. Article ; Online: Developments in Dedicated Prostate PET Instrumentation.

    Gonzalez, Antonio J / Gonzalez-Montoro, Andrea

    PET clinics

    2023  Volume 19, Issue 1, Page(s) 49–57

    Abstract: This article summarizes the evolution of dedicated prostate PET instrumentation. It starts by introducing prostate cancer, as well as the most common diagnostic and staging methods that are used in the clinics. Then, it describes the key aspects of PET ... ...

    Abstract This article summarizes the evolution of dedicated prostate PET instrumentation. It starts by introducing prostate cancer, as well as the most common diagnostic and staging methods that are used in the clinics. Then, it describes the key aspects of PET detectors and their assembly in full PET scanners highlighting the most suitable geometries for prostate examination, and a review on the existing prostate dedicated PET. Finally, the next steps for extending the use of PET in the daily diagnose, staging, and image-guided biopsy of patients with prostate cancer are discussed.
    MeSH term(s) Male ; Humans ; Prostate/diagnostic imaging ; Prostate/pathology ; Positron Emission Tomography Computed Tomography/methods ; Prostatic Neoplasms/diagnostic imaging ; Prostatic Neoplasms/pathology ; Prostate-Specific Antigen ; Gallium Radioisotopes
    Chemical Substances Prostate-Specific Antigen (EC 3.4.21.77) ; Gallium Radioisotopes
    Language English
    Publishing date 2023-09-29
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2764575-7
    ISSN 1879-9809 ; 1556-8598
    ISSN (online) 1879-9809
    ISSN 1556-8598
    DOI 10.1016/j.cpet.2023.06.001
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    Einzelsignatur: Show issues

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  4. Article ; Online: Recent advances in allogeneic transplantation for acute myeloid leukemia.

    Montoro, Juan / Balaguer-Roselló, Aitana / Sanz, Jaime

    Current opinion in oncology

    2023  Volume 35, Issue 6, Page(s) 564–573

    Abstract: Purpose of review: This review highlights recent advancements in allogeneic hematopoietic stem cell transplantation (allo-HSCT) for patients with acute myeloid leukemia (AML).: Recent findings: Important improvements have been observed throughout the ...

    Abstract Purpose of review: This review highlights recent advancements in allogeneic hematopoietic stem cell transplantation (allo-HSCT) for patients with acute myeloid leukemia (AML).
    Recent findings: Important improvements have been observed throughout the allo-HSCT procedure and patient management. Universal donor availability and reduced risk of graft-versus-host disease (GVHD) have been achieved with the introduction of posttransplant cyclophosphamide for GVHD prophylaxis. It has contributed, together with advances in conditioning regimens, GVHD treatment and supportive care, to a reduced overall toxicity of the procedure. Relapse is now the most frequent cause of transplant failure. With increased knowledge of the biological characterization of AML, better prediction of transplant risks and more profound and standardized minimal residual disease (MRD) monitoring, pharmacological, and immunological strategies to prevent relapse are been developed.
    Summary: Allo-HSCT remains the standard of care for high-risk AML. Increased access to transplant, reduced toxicity and relapse are improving patient outcomes. Further research is needed to optimize MRD monitoring, refine conditioning regimens, and explore new GVHD management and relapse prevention therapies.
    MeSH term(s) Humans ; Leukemia, Myeloid, Acute/drug therapy ; Transplantation, Homologous/methods ; Cyclophosphamide ; Hematopoietic Stem Cell Transplantation/adverse effects ; Hematopoietic Stem Cell Transplantation/methods ; Graft vs Host Disease/etiology ; Graft vs Host Disease/prevention & control ; Recurrence ; Transplantation Conditioning/methods ; Retrospective Studies
    Chemical Substances Cyclophosphamide (8N3DW7272P)
    Language English
    Publishing date 2023-08-30
    Publishing country United States
    Document type Review ; Journal Article
    ZDB-ID 1049384-0
    ISSN 1531-703X ; 1040-8746
    ISSN (online) 1531-703X
    ISSN 1040-8746
    DOI 10.1097/CCO.0000000000000992
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    Zs.A 3046: Show issues Location:
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  5. Article ; Online: PET System Technology: Theoretical Aspects and Experimental Methodology.

    Gonzalez-Montoro, Andrea / Levin, Craig S

    Methods in molecular biology (Clifton, N.J.)

    2023  Volume 2729, Page(s) 343–369

    Abstract: Positron emission tomography (PET) imaging provides unique information of the cellular and molecular pathways of disease occurring within the human body, using measurements made from outside the body, which has shown utility in a variety of studies from ... ...

    Abstract Positron emission tomography (PET) imaging provides unique information of the cellular and molecular pathways of disease occurring within the human body, using measurements made from outside the body, which has shown utility in a variety of studies from basic research to clinical applications. This chapter describes some of the most relevant PET system parameters that impact its imaging performance such as 3D spatial, energy, and coincidence timing resolutions and the methodology typically used to evaluate those parameters. In addition, the physical principles underlying PET imaging, PET photon detector technology, and coincidence detection are also described. As a closing remark, the future perspectives of PET imaging and its simultaneous use with anatomical imaging techniques (e.g., computed tomography [CT] and magnetic resonance imaging [MRI]) are outlined.
    MeSH term(s) Humans ; Positron-Emission Tomography/methods ; Tomography, X-Ray Computed ; Magnetic Resonance Imaging/methods ; Photons
    Language English
    Publishing date 2023-11-25
    Publishing country United States
    Document type Journal Article
    ISSN 1940-6029
    ISSN (online) 1940-6029
    DOI 10.1007/978-1-0716-3499-8_20
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  6. Article ; Online: Type 1 diabetes-related distress: Current implications in care.

    Rodríguez-Muñoz, Alba / Picón-César, María José / Tinahones, Francisco J / Martínez-Montoro, José Ignacio

    European journal of internal medicine

    2024  

    Abstract: Type 1 diabetes (T1D) is a complex chronic disease associated with major health and economic consequences, also involving important issues in the psychosocial sphere. In this regard, T1D-related distress, defined as the emotional burden of living with ... ...

    Abstract Type 1 diabetes (T1D) is a complex chronic disease associated with major health and economic consequences, also involving important issues in the psychosocial sphere. In this regard, T1D-related distress, defined as the emotional burden of living with T1D, has emerged as a specific entity related to the disease. Diabetes distress (DD) is an overlooked but prevalent condition in people living with T1D, and has significant implications in both glycemic control and mental health in this population. Although overlapping symptoms may be found between DD and mental health disorders, specific approaches should be performed for the diagnosis of this problem. In recent years, different DD-targeted interventions have been postulated, including behavioral and psychosocial strategies. Moreover, new technologies in this field may be helpful to address DD in people living with T1D. In this article, we summarize the current knowledge on T1D-related distress, and we also discuss the current approaches and future perspectives in its management.
    Language English
    Publishing date 2024-04-11
    Publishing country Netherlands
    Document type Journal Article ; Review
    ZDB-ID 1038679-8
    ISSN 1879-0828 ; 0953-6205
    ISSN (online) 1879-0828
    ISSN 0953-6205
    DOI 10.1016/j.ejim.2024.03.030
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    Zs.A 2608: Show issues Location:
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  7. Article: Exploring the Prevalence of Antimicrobial Resistance in

    Marco-Fuertes, Ana / Vega, Santiago / Villora-Gonzalez, José / Marin, Clara / Montoro-Dasi, Laura

    Life (Basel, Switzerland)

    2024  Volume 14, Issue 2

    Abstract: Companion animal ownership has evolved to new exotic animals, including small mammals, posing a new public health challenge, especially due to the ability of some of these new species to harbour zoonotic bacteria, such ... ...

    Abstract Companion animal ownership has evolved to new exotic animals, including small mammals, posing a new public health challenge, especially due to the ability of some of these new species to harbour zoonotic bacteria, such as
    Language English
    Publishing date 2024-01-24
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662250-6
    ISSN 2075-1729
    ISSN 2075-1729
    DOI 10.3390/life14020170
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  8. Article ; Online: Structural and functional neuroimaging of the effects of the gut microbiome.

    Montoro, Rodrigo A / Singh, Ajay P / Yu, John-Paul J

    European radiology

    2022  Volume 32, Issue 6, Page(s) 3683–3692

    Abstract: Interactions between intestinal microbiota and the central nervous system profoundly influence brain structure and function. Over the past 15 years, intense research efforts have uncovered the significant association between gut microbial dysbiosis and ... ...

    Abstract Interactions between intestinal microbiota and the central nervous system profoundly influence brain structure and function. Over the past 15 years, intense research efforts have uncovered the significant association between gut microbial dysbiosis and neurologic, neurodegenerative, and psychiatric disorders; however, our understanding of the effect of gut microbiota on quantitative neuroimaging measures of brain microstructure and function remains limited. Many current gut microbiome studies specifically focus on discovering correlations between specific microbes and neurologic disease states that, while important, leave critical mechanistic questions unanswered. To address this significant gap in knowledge, quantitative structural and functional brain imaging has emerged as a vital bridge and as the next step in understanding how the gut microbiome influences the brain. In this review, we examine the current state-of-the-art, raise awareness of this important topic, and aim to highlight immense new opportunities-in both research and clinical imaging-for the imaging community in this emerging field of study. Our review also highlights the potential for preclinical imaging of germ-free and gnotobiotic models to significantly advance our understanding of the causal mechanisms by which the gut microbiome alters neural microstructure and function. KEY POINTS: • Alterations to the gut microbiome can significantly influence brain structure and function in health and disease. • Quantitative neuroimaging can help elucidate the effect of gut microbiota on the brain and with future translational advances, neuroimaging will be critical for both diagnostic assessment and therapeutic monitoring.
    MeSH term(s) Brain/diagnostic imaging ; Dysbiosis/etiology ; Functional Neuroimaging ; Gastrointestinal Microbiome ; Humans ; Neuroimaging
    Language English
    Publishing date 2022-01-14
    Publishing country Germany
    Document type Journal Article ; Review
    ZDB-ID 1085366-2
    ISSN 1432-1084 ; 0938-7994 ; 1613-3749
    ISSN (online) 1432-1084
    ISSN 0938-7994 ; 1613-3749
    DOI 10.1007/s00330-021-08486-5
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    Zs.A 3300: Show issues Location:
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  9. Article ; Online: Chorea hyperglycemia basal ganglia syndrome.

    Valle Alonso, Joaquín / Noblia Gamba, Leandro / Montoro Jorquera, Esther

    Medicina clinica

    2023  Volume 161, Issue 7, Page(s) 316–317

    Title translation Síndrome de corea hiperglucémica de ganglios basales.
    Language Spanish
    Publishing date 2023-07-06
    Publishing country Spain
    Document type Letter
    ZDB-ID 411607-0
    ISSN 1578-8989 ; 0025-7753
    ISSN (online) 1578-8989
    ISSN 0025-7753
    DOI 10.1016/j.medcli.2023.03.034
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  10. Article ; Online: A Proactive Behavioral Activities Program (EWA) and the Influence of COVID-19 among Seniors in Congregate Living Communities.

    Montoro-Rodriguez, Julian / Hayslip, Bert / Ramsey, Jennifer

    Journal of applied gerontology : the official journal of the Southern Gerontological Society

    2022  Volume 41, Issue 10, Page(s) 2214–2225

    Abstract: Older adults in affordable housing are at risk for mental health problems, physical vulnerability, and isolation. We examine the role of an activities program in buffering the influence of life stressors on the mental health of seniors in congregate ... ...

    Abstract Older adults in affordable housing are at risk for mental health problems, physical vulnerability, and isolation. We examine the role of an activities program in buffering the influence of life stressors on the mental health of seniors in congregate housing, using a non-experimental pretest-posttest study design. Results based upon repeated measures analyses (N = 29), found statistically significant (p < .05) program by time effects for depression, coping strategies, positive affect, isolation, and resident satisfaction. Analyses based upon independent samples of pretest and posttest measures (N = 60) were considerably less strong, but consistent in yielding similar patterns to those of the longitudinally gathered data. Our longitudinal findings substantiate the positive impact of the Engage with Age program in supporting older adults living in congregate housing. Researchers need to develop strategies to assess and support the mental health of older persons in low-income urban congregate living in the larger context of COVID-19.
    MeSH term(s) Adaptation, Psychological ; Aged ; Aged, 80 and over ; COVID-19/epidemiology ; Housing ; Humans ; Personal Satisfaction ; Poverty
    Language English
    Publishing date 2022-06-13
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 155897-3
    ISSN 1552-4523 ; 0733-4648
    ISSN (online) 1552-4523
    ISSN 0733-4648
    DOI 10.1177/07334648221108279
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