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  1. Article ; Online: New hope to prevent ALL relapse after transplant.

    Bishop, Michael R

    Blood

    2022  Volume 139, Issue 17, Page(s) 2580–2581

    MeSH term(s) Cell- and Tissue-Based Therapy ; Chronic Disease ; Humans ; Leukemia ; Recurrence ; Tissue Donors ; Transplants
    Language English
    Publishing date 2022-05-02
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 80069-7
    ISSN 1528-0020 ; 0006-4971
    ISSN (online) 1528-0020
    ISSN 0006-4971
    DOI 10.1182/blood.2022015611
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  2. Article ; Online: CAR T-cell therapy: A collaboration between authorized treatment centers and community oncologists.

    Bishop, Michael R / Kay, Gary E

    Seminars in oncology

    2024  

    Abstract: ... these autologous cell therapies have changed the treatment paradigm for patients with relapsed or refractory (r/r ... clinical benefit in patients with r/r diffuse large B-cell lymphoma, mantle cell lymphoma, and ...

    Abstract With the approval of the first CAR T-cell products for hematological malignancies in 2017, these autologous cell therapies have changed the treatment paradigm for patients with relapsed or refractory (r/r) non-Hodgkin lymphoma (NHL), who have a poor prognosis and few effective treatment options. Despite the demonstrated clinical benefit in patients with r/r diffuse large B-cell lymphoma, mantle cell lymphoma, and follicular lymphoma, many patients who are eligible for CAR T-cell therapies do not receive them or are treated with CAR T cells as a later line of therapy at advanced stages of disease. Several barriers exist for referring patients to an authorized treatment center (ATC) for CAR T-cell therapy. Although most patients with NHL are treated by community-based oncologists, educational gaps may exist for some community oncologists about the availability of CAR T-cell therapies in certain indications, the overall treatment process, and how they can access these therapies for their patients. In addition to navigation of the referral process from the community setting to the ATC, other barriers include timely identification of candidates eligible for CAR T-cell therapy and logistical and reimbursement concerns. Here, we examine the patient CAR T-cell experience, which begins and ends in the community setting, and identify and discuss opportunities for improved collaboration between community oncologists and ATC physicians to help address barriers to treatment and enhance patient outcomes. Treatment decisions for a patient's second or third line of therapy for NHL are critically important, owing to declining probabilities for favorable outcomes with each successive line of therapy. For patients who are eligible, CAR T-cell therapies should be considered as early as possible in their treatment course. A better understanding of the CAR T-cell process, the patient's experience, and the collaboration necessary for timely patient identification, better access, and successful outcomes will enable more patients to benefit from CAR T-cell therapies.
    Language English
    Publishing date 2024-02-22
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 189220-4
    ISSN 1532-8708 ; 0093-7754
    ISSN (online) 1532-8708
    ISSN 0093-7754
    DOI 10.1053/j.seminoncol.2024.02.001
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  3. Book: Hematopoietic stem cell transplantation

    Bishop, Michael R.

    (Cancer Treatment and Research ; 144)

    2009  

    Author's details Michael R. Bishop ed
    Series title Cancer Treatment and Research ; 144
    Cancer treatment and research
    Collection Cancer treatment and research
    Keywords Hematopoietic Stem Cells ; Bone Marrow ; Bone Marrow Transplantation ; Hematopoietic Stem Cell Transplantation
    Language English
    Size XV, 589 S. : graph. Darst.
    Publisher Springer
    Publishing place New York, NY
    Publishing country United States
    Document type Book
    HBZ-ID HT015784590
    ISBN 978-0-387-78579-0 ; 0-387-78579-5 ; 9780387785806 ; 0387785809
    Database Catalogue ZB MED Medicine, Health

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    Shelf markLoan statusLocation
    2009 A 2 order for loan Magazin

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  4. Article ; Online: The benefit of CAR T cells in older patients.

    Bishop, Michael R

    Blood

    2020  Volume 135, Issue 23, Page(s) 2020–2021

    MeSH term(s) Aged ; Antigens, CD19/therapeutic use ; Humans ; Immunotherapy, Adoptive ; Lymphoma, B-Cell ; T-Lymphocytes/immunology
    Chemical Substances Antigens, CD19 ; axicabtagene ciloleucel (U2I8T43Y7R)
    Language English
    Publishing date 2020-07-09
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 80069-7
    ISSN 1528-0020 ; 0006-4971
    ISSN (online) 1528-0020
    ISSN 0006-4971
    DOI 10.1182/blood.2020005592
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  5. Article: Optimizing Administration of CAR T-Cell Therapy During the COVID-19 Pandemic.

    Bishop, Michael R

    Clinical advances in hematology & oncology : H&O

    2020  Volume 18, Issue 7, Page(s) 400–403

    MeSH term(s) Betacoronavirus/immunology ; Betacoronavirus/pathogenicity ; CD4-Positive T-Lymphocytes/immunology ; CD4-Positive T-Lymphocytes/pathology ; CD4-Positive T-Lymphocytes/virology ; COVID-19 ; Coronavirus Infections/complications ; Coronavirus Infections/immunology ; Coronavirus Infections/pathology ; Coronavirus Infections/therapy ; Cytokine Release Syndrome/complications ; Cytokine Release Syndrome/immunology ; Cytokine Release Syndrome/pathology ; Cytokine Release Syndrome/therapy ; Cytotoxicity, Immunologic ; Gene Expression ; Hematologic Neoplasms/complications ; Hematologic Neoplasms/immunology ; Hematologic Neoplasms/pathology ; Hematologic Neoplasms/therapy ; Humans ; Immunotherapy, Adoptive/methods ; Lymphocyte Activation ; Pandemics ; Pneumonia, Viral/complications ; Pneumonia, Viral/immunology ; Pneumonia, Viral/pathology ; Pneumonia, Viral/therapy ; Receptors, Antigen, T-Cell/genetics ; Receptors, Antigen, T-Cell/immunology ; SARS-CoV-2 ; Severity of Illness Index ; T-Lymphocytes, Cytotoxic/immunology ; T-Lymphocytes, Cytotoxic/pathology ; T-Lymphocytes, Cytotoxic/virology
    Chemical Substances Receptors, Antigen, T-Cell
    Keywords covid19
    Language English
    Publishing date 2020-08-31
    Publishing country United States
    Document type Interview
    ZDB-ID 2271951-9
    ISSN 1543-0790
    ISSN 1543-0790
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: The case for CAR T-cell therapy in follicular lymphomas.

    Bishop, Michael R

    Blood

    2019  Volume 134, Issue 7, Page(s) 577–578

    MeSH term(s) Automobiles ; Humans ; Immunotherapy ; Immunotherapy, Adoptive ; Lymphoma, Follicular ; T-Lymphocytes
    Language English
    Publishing date 2019-07-21
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 80069-7
    ISSN 1528-0020 ; 0006-4971
    ISSN (online) 1528-0020
    ISSN 0006-4971
    DOI 10.1182/blood.2019001843
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  8. Article: Safety and efficacy of axicabtagene ciloleucel in refractory large B-cell lymphomas.

    Riedell, Peter A / Bishop, Michael R

    Therapeutic advances in hematology

    2020  Volume 11, Page(s) 2040620720902899

    Abstract: Aggressive large B-cell lymphomas represent a diverse population of diseases that are typically treated with anti-CD20 based immunochemotherapy. While this treatment is effective for a large proportion of patients, those that become refractory to ... ...

    Abstract Aggressive large B-cell lymphomas represent a diverse population of diseases that are typically treated with anti-CD20 based immunochemotherapy. While this treatment is effective for a large proportion of patients, those that become refractory to induction therapy or experience disease relapse suffer an inferior overall prognosis, and novel treatment options are needed. Adoptive T-cell immunotherapy in the form of chimeric antigen receptor (CAR) T-cell therapy is one of the most revolutionary breakthroughs in the past several decades for the treatment of relapsed/refractory aggressive large B-cell lymphomas. Based on data from the pivotal ZUMA-1 study, axicabtagene ciloleucel (axi-cel) became the first-in-class anti-CD19 directed CAR T-cell therapy approved for patients with diffuse large B-cell lymphoma and other aggressive B-cell lymphoma variants. In this review, we provide an overview of CAR T-cell therapy, including its biology, manufacturing, and treatment course. In addition, we highlight the available efficacy data, review pertinent safety concerns, including cytokine release syndrome and neurologic toxicity, as well as provide an overview of emerging therapeutic strategies in the cellular therapy arena.
    Language English
    Publishing date 2020-01-29
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2585183-4
    ISSN 2040-6215 ; 2040-6207
    ISSN (online) 2040-6215
    ISSN 2040-6207
    DOI 10.1177/2040620720902899
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Book ; Online: Atlas of Butterflies and Diurnal Moths in the Monsoon Tropics of Northern Australia

    Coppen, Rebecca / Bishop, Carly / Williams, Andrew / Bisa, Deborah / Williams, Matthew / Franklin, Donald / Braby, Michael

    2018  

    Abstract: Northern Australia is one of few tropical places left on Earth in which biodiversity-and the ecological processes underpinning that biodiversity-is still relatively intact. However, scientific knowledge of that biodiversity is still in its infancy and ... ...

    Abstract Northern Australia is one of few tropical places left on Earth in which biodiversity-and the ecological processes underpinning that biodiversity-is still relatively intact. However, scientific knowledge of that biodiversity is still in its infancy and the region remains a frontier for biological discovery. The butterfly and diurnal moth assemblages of the area, and their intimate associations with vascular plants (and sometimes ants), exemplify these points.However, the opportunity to fill knowledge gaps is quickly closing: proposals for substantial development and exploitation of Australia's north will inevitably repeat the ecological devastation that has occurred in temperate southern Australia-loss of species, loss of ecological communities, fragmentation of populations, disruption of healthy ecosystem function and so on-all of which will diminish the value of the natural heritage of the region before it is fully understood and appreciated. Written by several experts in the field, the main purpose of this atlas is to compile a comprehensive inventory of the butterflies and diurnal moths of northern Australia to form the scientific baseline against which the extent and direction of change can be assessed in the future. Such information will also assist in identifying the region's biological assets, to inform policy and management agencies and to set priorities for biodiversity conservation
    Keywords Environmental sciences
    Size 1 electronic resource (462 p.)
    Publisher ANU Press
    Document type Book ; Online
    Note English ; Open Access
    HBZ-ID HT020101055
    ISBN 9781760462321 ; 1760462322
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  10. Article ; Online: Exploring Consumer Preferences for Cannabis Vaping Products to Support Public Health Policy: A Discrete Choice Experiment.

    Donnan, Jennifer R / Johnston, Karissa / Coombs, Michael / Najafizada, Maisam / Bishop, Lisa D

    Applied health economics and health policy

    2023  Volume 21, Issue 4, Page(s) 651–659

    Abstract: Background: Phase two of cannabis legalisation in Canada brought cannabis vaping products to the market. This decision was controversial due to an outbreak of vaping cannabis use-associated lung injury. This resulted in three provinces banning the sale ... ...

    Abstract Background: Phase two of cannabis legalisation in Canada brought cannabis vaping products to the market. This decision was controversial due to an outbreak of vaping cannabis use-associated lung injury. This resulted in three provinces banning the sale of cannabis vaping products causing inequitable access. This study sought to explore consumer preferences for cannabis vaping products to inform cannabis policy.
    Methods: We used a discrete choice experiment to explore consumer preferences for attributes of cannabis vaping products. Attributes included type of device, price, tetrahydrocannabinol (THC) potency, vape liquid content, product recommendations and Health Canada regulation. Participants lived in Canada, were aged ≥ 19 years, and had purchased a cannabis vape in the last 12 months. A multinomial logit (MNL) model was used for the base model, and latent class analysis to assess preference sub-groups.
    Results: In total, 384 participants completed the survey; the MNL model showed that price and potency were the most important attributes. A three-group latent class model showed that ~ 40% of the sample was driven primarily by Health Canada Regulation and were willing to pay $56 more for a product that was regulated compared to one that was not. About 33% of the sample was driven by price, and 26% was driven by type of device.
    Conclusion: While regulated status by Health Canada was most important to some consumers (~ 40%), nearly 60% of the sample were willing to make trade-offs in regulated status for products with a lower price. Therefore, policymakers need to consider the broader public health implications of banning cannabis vapes in some regions.
    MeSH term(s) Humans ; Vaping ; Cannabis ; Consumer Behavior ; Dronabinol ; Health Policy
    Chemical Substances Dronabinol (7J8897W37S)
    Language English
    Publishing date 2023-04-15
    Publishing country New Zealand
    Document type Journal Article
    ZDB-ID 2171420-4
    ISSN 1179-1896 ; 1175-5652
    ISSN (online) 1179-1896
    ISSN 1175-5652
    DOI 10.1007/s40258-023-00804-w
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