LIVIVO - Search results -

Search results

Result 1 - 10 of total 100

Search options

Article: COST ANALYSIS OF MOTORCYCLE ACCIDENT VICTIMS AT A UNIVERSITY HOSPITAL: PERSPECTIVES FROM 2017 AND 2020.

Baptistella, Amanda / Figueiredo, Henrique Carvalho E Silva / de Mattos, Carlos Augusto / Bittar, Cintia Kelly

2023 Volume 31, Issue spe1, Page(s) e258318

Abstract: Introduction: Motorcycle accidents constitute a public health problem that affects public and private health services due to the expenses of the victim's treatment and rehabilitation.: Objective: Evaluate the impact of motorcycle accident costs in a ... ...

Abstract	Introduction: Motorcycle accidents constitute a public health problem that affects public and private health services due to the expenses of the victim's treatment and rehabilitation. Objective: Evaluate the impact of motorcycle accident costs in a university hospital in 2020. Method: Comparative analysis of the costs of motorcycle accident patients in 2020 and 2017. Results: Among 151 patients included in the study, the average cost was U$3,083.54, and the average days of hospitalization were 5.3 days. The patient with the highest cost to the hospital spent U$22,504.05, and the patient with the lowest cost spent U$356.72. The longest stay among these patients was 41 days, and the shortest was one day. The average cost per patient per day for the entire sample was U$581.80. Conclusion: The formulation and application of strategies that promote the reduction of motorcycle accidents in the city of Campinas are necessary.
Language	English
Publishing date	2023-04-17
Publishing country	Brazil
Document type	Journal Article
ZDB-ID	2105206-2
ISSN	1809-4406 ; 1413-7852
ISSN (online)	1809-4406
ISSN	1413-7852
DOI	10.1590/1413-785220233101e258318
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

Article ; Online: COST ANALYSIS OF MOTORCYCLE ACCIDENT VICTIMS AT A UNIVERSITY HOSPITAL

Amanda Baptistella / Henrique Carvalho e Silva Figueiredo / Carlos Augusto de Mattos / Cintia Kelly Bittar

Acta Ortopédica Brasileira, Vol 31, Iss spe

PERSPECTIVES FROM 2017 AND 2020

2023 Volume 1

Abstract: ABSTRACT Introduction: Motorcycle accidents constitute a public health problem that affects public and private health services due to the expenses of the victim's treatment and rehabilitation. Objective: Evaluate the impact of motorcycle accident costs ... ...

Abstract	ABSTRACT Introduction: Motorcycle accidents constitute a public health problem that affects public and private health services due to the expenses of the victim's treatment and rehabilitation. Objective: Evaluate the impact of motorcycle accident costs in a university hospital in 2020. Method: Comparative analysis of the costs of motorcycle accident patients in 2020 and 2017. Results: Among 151 patients included in the study, the average cost was U$3,083.54, and the average days of hospitalization were 5.3 days. The patient with the highest cost to the hospital spent U$22,504.05, and the patient with the lowest cost spent U$356.72. The longest stay among these patients was 41 days, and the shortest was one day. The average cost per patient per day for the entire sample was U$581.80. Conclusion: The formulation and application of strategies that promote the reduction of motorcycle accidents in the city of Campinas are necessary. Level of evidence II, Retrospective study.
Keywords	Accidents ; Traffic ; Hospitalization ; Costs and Cost Analysis ; Medicine ; R ; Orthopedic surgery ; RD701-811
Subject code	380
Language	English
Publishing date	2023-04-01T00:00:00Z
Publisher	Sociedade Brasileira de Ortopedia e Traumatologia
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

Full text online

Full text

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article ; Online: African ZIKV lineage fails to sustain infectivity in an in vitro mimetic urban cycle.

Molina, Bárbara Floriano / Marques, Nayara Nathiê / Bittar, Cíntia / Batista, Mariana Nogueira / Rahal, Paula

Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology

2023 Volume 54, Issue 3, Page(s) 1421–1431

Abstract: Zika virus (ZIKV) is an arbovirus maintained in nature in two distinct cycles of transmission: urban and sylvatic. Each cycle includes specific vertebrate and invertebrate hosts, and through alternate infections, a conserved consensus sequence is ... ...

Abstract	Zika virus (ZIKV) is an arbovirus maintained in nature in two distinct cycles of transmission: urban and sylvatic. Each cycle includes specific vertebrate and invertebrate hosts, and through alternate infections, a conserved consensus sequence is maintained that might vary depending on the cycle. The current study aimed to investigate the ability of ZIKV
MeSH term(s)	Animals ; Humans ; Zika Virus/genetics ; Zika Virus Infection ; Aedes ; Brazil
Language	English
Publishing date	2023-07-17
Publishing country	Brazil
Document type	Journal Article
ZDB-ID	2017175-4
ISSN	1678-4405 ; 1517-8382
ISSN (online)	1678-4405
ISSN	1517-8382
DOI	10.1007/s42770-023-01053-8
Database	MEDical Literature Analysis and Retrieval System OnLINE

Full text online

Accessible to users with ZB MED library card

Order via subito

Details ▾
- Full text online
- Order with fees

Article: CLINICAL AND FUNCTIONAL EVALUATION OF WRISTS AND HANDS OF SPINAL CORD INJURED PATIENTS.

Bittar, Cíntia Kelly / Perucci, Isabela Ferreira / Signorini, Danillo Nagel / Mascarenhas, Mariana Buratti / Silvestre, Orcizo Francisco / Cliquet, Alberto

Acta ortopedica brasileira

2024 Volume 32, Issue 1, Page(s) e264175

Abstract: Introduction: The inability of the spinal cord to propagate sensory and motor stimuli as a result of the disruption of the nerve tracts is called spinal cord injury.: Objective: This study analyzes clinically and radiologically the hands and wrists ... ...

Abstract	Introduction: The inability of the spinal cord to propagate sensory and motor stimuli as a result of the disruption of the nerve tracts is called spinal cord injury. Objective: This study analyzes clinically and radiologically the hands and wrists of spinal cord injured patients, evaluating their motor and sensitive functionality, in order to determine if these patients are more likely to develop degenerative alterations. Methods: 14 patients (8 paraplegics and 6 tetraplegics) were evaluated, undergoing anamnesis and clinical examination - a scale of muscular strength (MRC - Medical Research Council) and the amplitude measurement of the movement with a manual goniometer (ROM), were used for objective evaluation - and x-ray exams. The results were compared with pre-existing data from other studies. Results: When asked, only one of the 14 observed patients complained about constant wrist pain, described as level 3 (weak to moderate), based on the visual analog scale (VAS). The motor evaluation, MRC and ROM divided the group of patients into two subgroups: paraplegic and tetraplegic patients. The x-ray analysis showed, based on Kellgren and Lawrence classification, that all exam images fit grades 1 or 2 of osteoarthritis and osteoarthrosis. Conclusion: In conclusion, spinal cord injured patients showed none or minimal clinical and radiological signs of osteoarthritis on hands or wrists. Overall, the hands and wrists of spinal cord-injured patients behave similarly to noninjured patients.
Language	English
Publishing date	2024-03-22
Publishing country	Brazil
Document type	Journal Article
ZDB-ID	2105206-2
ISSN	1809-4406 ; 1413-7852
ISSN (online)	1809-4406
ISSN	1413-7852
DOI	10.1590/1413-785220243201e264175
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article: THE IMPACT OF MOTORCYCLE ACCIDENTS IN A REFERENCE HOSPITAL DURING THE COVID-19 PANDEMIC.

Rocha, Aline Cremasco / Valente, Bruna Granig / Figueiredo, Henrique Carvalho E Silva / Jorge, Guilherme DE Oliveira / Mattos, Carlos Augusto DE / Bittar, Cintia Kelly

Acta ortopedica brasileira

2022 Volume 30, Issue 5, Page(s) e255862

Abstract: Objective: This study aimed to analyze the relationship between the number of motorcycle accidents attended at a reference Hospital for trauma in Campinas, state of São Paulo, and the pandemic by COVID-19 during the year 2020.: Methods: This is a ... ...

Abstract	Objective: This study aimed to analyze the relationship between the number of motorcycle accidents attended at a reference Hospital for trauma in Campinas, state of São Paulo, and the pandemic by COVID-19 during the year 2020. Methods: This is a cross-sectional, descriptive retrospective study carried out at Hospital PUC- Campinas, through the analysis of medical records of patients, victims of motorcycle trauma undergoing orthopedic surgical management in 2020. The phases of the pandemic and the isolation rates according to the São Paulo Plan were studied. Chi-Square tests, and the Least Squares method were applied for statistical calculations. Results: 155 medical records were analyzed, of which 91.61% of the patients were male. Of those admitted, 94.84% suffered fractures and 51.61%, polyfractures. There was a correlation between the average isolation rates and the number of accidents. In the 14-day period, as the average isolation rate increased by 10%, there was an increase of approximately 3 accidents in that period. In the 7-day analysis, 1.7 more traumas were observed for every 10% increase in the average isolation. Conclusion: The results suggest that by increasing the average isolation rate, the number of traumas per motorcycle treated at the institution increased.
Language	English
Publishing date	2022-11-11
Publishing country	Brazil
Document type	Journal Article
ZDB-ID	2105206-2
ISSN	1809-4406 ; 1413-7852
ISSN (online)	1809-4406
ISSN	1413-7852
DOI	10.1590/1413-785220223005e255862
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Antiviral Evaluation of New Synthetic Bioconjugates Based on GA-Hecate: A New Class of Antivirals Targeting Different Steps of Zika Virus Replication.

da Silva Sanches, Paulo Ricardo / Velazquez, Ricardo Sanchez / Batista, Mariana Nogueira / Carneiro, Bruno Moreira / Bittar, Cintia / De Lorenzo, Giuditta / Rahal, Paula / Patel, Arvind H / Cilli, Eduardo Maffud

Molecules (Basel, Switzerland)

2023 Volume 28, Issue 13

Abstract: Re-emerging arboviruses represent a serious health problem due to their rapid vector-mediated spread, mainly in urban tropical areas. The 2013-2015 Zika virus (ZIKV) outbreak in South and Central America has been associated with cases of microcephaly in ... ...

Abstract	Re-emerging arboviruses represent a serious health problem due to their rapid vector-mediated spread, mainly in urban tropical areas. The 2013-2015 Zika virus (ZIKV) outbreak in South and Central America has been associated with cases of microcephaly in newborns and Guillain-Barret syndrome. We previously showed that the conjugate gallic acid-Hecate (GA-FALALKALKKALKKLKKALKKAL-CONH
MeSH term(s)	Infant, Newborn ; Humans ; Zika Virus ; Antiviral Agents/chemistry ; Zika Virus Infection ; Virus Replication ; Dermatologic Agents/pharmacology ; Gallic Acid/pharmacology
Chemical Substances	Antiviral Agents ; Dermatologic Agents ; Gallic Acid (632XD903SP)
Language	English
Publishing date	2023-06-21
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	1413402-0
ISSN	1420-3049 ; 1431-5165 ; 1420-3049
ISSN (online)	1420-3049
ISSN	1431-5165 ; 1420-3049
DOI	10.3390/molecules28134884
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.MO 81: Show issues

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Identification of differentially expressed miRNAs in human cells infected with different Zika virus strains.

Machado, Francielly Cristina / Bittar, Cíntia / Rahal, Paula / Calmon, Marilia Freitas

Archives of virology

2021 Volume 166, Issue 6, Page(s) 1681–1689

Abstract: Infection with distinct Zika virus (ZIKV) strains in in vitro and in vivo models has demonstrated that the host's response to infection is strain-dependent. There has been no analysis of the impact of infection with different ZIKV strains on miRNA ... ...

Abstract	Infection with distinct Zika virus (ZIKV) strains in in vitro and in vivo models has demonstrated that the host's response to infection is strain-dependent. There has been no analysis of the impact of infection with different ZIKV strains on miRNA expression in human cells. We investigated miRNA expression in PNT1A cells upon infection with an African ZIKV strain (MR766) and a Brazilian ZIKV strain (ZIKV
MeSH term(s)	Animals ; Chlorocebus aethiops ; Epithelial Cells/metabolism ; Epithelial Cells/virology ; Gene Expression Regulation/immunology ; Gene Regulatory Networks ; Humans ; MicroRNAs/genetics ; MicroRNAs/metabolism ; Vero Cells ; Zika Virus/classification
Chemical Substances	MicroRNAs
Language	English
Publishing date	2021-04-13
Publishing country	Austria
Document type	Journal Article
ZDB-ID	7491-3
ISSN	1432-8798 ; 0304-8608
ISSN (online)	1432-8798
ISSN	0304-8608
DOI	10.1007/s00705-021-05051-9
Database	MEDical Literature Analysis and Retrieval System OnLINE

Full text online

Accessible to users with ZB MED library card

In stock of ZB MED Cologne/Königswinter

Ud II Zs.110: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾

Article ; Online: Detection of DENV-2 and ZIKV coinfection in southeastern Brazil by serum and urine testing.

da Conceição, Pâmela Jóyce Previdelli / de Carvalho, Lucas Rodrigues / de Godoy, Bianca Lara Venâncio / Nogueira, Mauricio Lacerda / Terzian, Ana Carolina Bernardes / de Godoy, Moacir Fernandes / Calmon, Marília Freitas / Bittar, Cintia / Rahal, Paula

Medical microbiology and immunology

2023 Volume 212, Issue 3, Page(s) 193–201

Abstract: Purpose: Aedes aegypti mosquito-borne diseases have a significant impact on public health in Brazil. In this study, we investigated the presence of the Zika virus (ZIKV) and dengue virus (DENV) in serum and urine samples from symptomatic participants ... ...

Abstract	Purpose: Aedes aegypti mosquito-borne diseases have a significant impact on public health in Brazil. In this study, we investigated the presence of the Zika virus (ZIKV) and dengue virus (DENV) in serum and urine samples from symptomatic participants who attended an Emergency Care Unit located in a city in the northwestern region of São Paulo between February 2018 and April 2019. Methods: Serum and urine samples were collected from participants suspected of having arbovirus infection. After the extraction of viral RNA, viral detection was performed by real-time quantitative reverse transcription polymerase chain reaction (RT-qPCR) (One-Step RT-qPCR). Results: A total of 305 participants participated in this study. A total of 283 blood and 270 urine samples were collected. Of 305 patients, 36.4% (111/305) were positive for ZIKV, 43.3% (132/305) for DENV2, and 0.3% (1/305) for DENV1. Coinfection with ZIKV/DENV2 was observed in 13.1% of participants. If only serum samples were used, ZIKV detection would have decreased to 23.3% (71/305). Of all the participants included in the study, only one was suspected of having ZIKV infection based on clinical diagnosis, and the remaining participants were suspected of having DENV. Conclusion: By testing serum and urine samples, we increased the detection of both viruses and detected considerable levels of ZIKV and DENV-2 coinfection when compared to other studies. Additionally, we detected an unnoticed ZIKV outbreak in the city. These findings highlight the importance of the molecular diagnosis of arboviruses to aid public health surveillance and management strategies.
MeSH term(s)	Animals ; Humans ; Zika Virus ; Zika Virus Infection/diagnosis ; Zika Virus Infection/epidemiology ; Dengue/diagnosis ; Dengue/epidemiology ; Dengue Virus/genetics ; Coinfection/diagnosis ; Coinfection/epidemiology ; Brazil/epidemiology ; Chikungunya Fever/diagnosis ; Chikungunya Fever/epidemiology ; Chikungunya virus/genetics
Language	English
Publishing date	2023-04-07
Publishing country	Germany
Document type	Journal Article
ZDB-ID	120933-4
ISSN	1432-1831 ; 0300-8584
ISSN (online)	1432-1831
ISSN	0300-8584
DOI	10.1007/s00430-023-00762-z
Database	MEDical Literature Analysis and Retrieval System OnLINE

Full text online

Accessible to users with ZB MED library card

In stock of ZB MED Cologne/Königswinter

Un I Zs.170: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾

Article ; Online: Antiviral Evaluation of New Synthetic Bioconjugates Based on GA-Hecate

Paulo Ricardo da Silva Sanches / Ricardo Sanchez Velazquez / Mariana Nogueira Batista / Bruno Moreira Carneiro / Cintia Bittar / Giuditta De Lorenzo / Paula Rahal / Arvind H. Patel / Eduardo Maffud Cilli

Molecules, Vol 28, Iss 4884, p

A New Class of Antivirals Targeting Different Steps of Zika Virus Replication

2023 Volume 4884

Abstract: Re-emerging arboviruses represent a serious health problem due to their rapid vector-mediated spread, mainly in urban tropical areas. The 2013–2015 Zika virus (ZIKV) outbreak in South and Central America has been associated with cases of microcephaly in ... ...

Abstract	Re-emerging arboviruses represent a serious health problem due to their rapid vector-mediated spread, mainly in urban tropical areas. The 2013–2015 Zika virus (ZIKV) outbreak in South and Central America has been associated with cases of microcephaly in newborns and Guillain–Barret syndrome. We previously showed that the conjugate gallic acid—Hecate (GA-FALALKALKKALKKLKKALKKAL-CONH 2 )—is an efficient inhibitor of the hepatitis C virus. Here, we show that the Hecate peptide is degraded in human blood serum into three major metabolites. These metabolites conjugated with gallic acid were synthesized and their effect on ZIKV replication in cultured cells was evaluated. The GA-metabolite 5 (GA-FALALKALKKALKKL-COOH) was the most efficient in inhibiting two ZIKV strains of African and Asian lineage at the stage of both virus entry (virucidal and protective) and replication (post-entry). We also demonstrate that GA-metabolite 5 does not affect cell growth after 7 days of continuous treatment. Thus, this study identifies a new synthetic antiviral compound targeting different steps of ZIKV replication in vitro and with the potential for broad reactivity against other flaviviruses. Our work highlights a promising strategy for the development of new antivirals based on peptide metabolism and bioconjugation.
Keywords	Zika virus ; gallic acid ; peptides ; Hecate ; bioconjugates ; GA-Hecate ; Organic chemistry ; QD241-441
Subject code	540 ; 570
Language	English
Publishing date	2023-06-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

Full text online

Full text

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article ; Online: Early infection of Zika virus in the male reproductive system of AG129 mice: molecular and immunohistochemical evaluation.

Lima, Maria Letícia Duarte / Cabral, Ágata Silva / Bittar, Cintia / Falleiros Junior, Luiz Roberto / Guerra, Luiz Henrique Alves / Carneiro, Bruno Moreira / de Souza Ferreira, Luis Carlos / Nogueira, Maurício Lacerda / Taboga, Sebastião Roberto / Calmon, Marilia Freitas / Rahal, Paula

Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology

2022 Volume 53, Issue 3, Page(s) 1279–1287

Abstract: Sexual transmission of Zika virus (ZIKV), an important arbovirus, and the virus persistence in semen raise several questions about how and where it circulates in the male reproductive system (MRS). Several studies reported detection of the virus in ... ...

Abstract	Sexual transmission of Zika virus (ZIKV), an important arbovirus, and the virus persistence in semen raise several questions about how and where it circulates in the male reproductive system (MRS). Several studies reported detection of the virus in testes, epididymis, and prostate at 5 days post-infection (dpi) or more in animal models. In the present study, we investigated the interactions of ZIKV with mouse MRS using the AG129 strain, a ZIKV permissive immunodeficient mouse strain, at two dpi. Viral RNA was detected in blood, testes, epididymis, and prostatic complexes (prostate and seminal vesicles). Immunohistochemical (IHC) analyses, based on the envelope protein, showed an early infection in organs of MRS since ZIKV positive antigens were detected in cells within or surrounding blood vessels, Sertoli, and germ cells in testes and epithelial cells in epididymis and prostate. Positive antigens for NS5 protein, the virus RNA-dependent RNA polymerase, were also detected by IHC in these organs and circulating leukocytes, suggesting that the virus replicates in these sites as early as 2 days post-infection. Analysis of the early stages of ZIKV infection in MRS may improve the current knowledge about this issue and contribute to the development of therapies directed to the infection at this site.
MeSH term(s)	Animals ; Genitalia, Male ; Male ; Mice ; RNA, Viral/genetics ; Semen ; Zika Virus/genetics ; Zika Virus Infection
Chemical Substances	RNA, Viral
Language	English
Publishing date	2022-04-23
Publishing country	Brazil
Document type	Journal Article
ZDB-ID	2017175-4
ISSN	1678-4405 ; 1517-8382
ISSN (online)	1678-4405
ISSN	1517-8382
DOI	10.1007/s42770-022-00761-x
Database	MEDical Literature Analysis and Retrieval System OnLINE

Full text online

Accessible to users with ZB MED library card

Order via subito

Details ▾
- Full text online
- Order with fees

To top

More links

Kategorien

Order via subito

Full text online

More links

Kategorien

Inter-library loan at ZB MED

Full text online

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

Full text online

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

Full text online

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

Full text online

More links

Kategorien

Inter-library loan at ZB MED

Full text online

More links

Kategorien

Order via subito