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  1. Article: Social distancing policy and mental health during COVID-19 pandemic: an 18-month longitudinal cohort study in South Korea.

    Bahk, Yong-Chun / Jung, Dawoon / Choi, Kee-Hong

    Frontiers in psychology

    2023  Volume 14, Page(s) 1256240

    Abstract: Background: Despite the effectiveness of social distancing policies in preventing the spread of Coronavirus Disease 2019 (COVID-19), their impact on mental health remains a concern. Longitudinal studies investigating the psychological effects of social ... ...

    Abstract Background: Despite the effectiveness of social distancing policies in preventing the spread of Coronavirus Disease 2019 (COVID-19), their impact on mental health remains a concern. Longitudinal studies investigating the psychological effects of social distancing are limited.
    Methods: Longitudinal data on psychological variables were collected eight times between May 2020 and November 2021 through online surveys in South Korea.
    Results: The participants in the study reported a worsening of depressive and anxiety symptoms, suicide risk, and psychological distress with increasing levels of social distancing. Specifically, during the third wave, when social distancing levels peaked, the highest levels of depression, anxiety, and psychological distress were observed, and the second-lowest levels of vitality were reported. Furthermore, psychological risk factors, such as depressive symptoms, anxiety symptoms, and suicidal risk, were closely associated with vitality levels in daily life.
    Discussions: During the pandemic, although social distancing helped prevent the spread of COVID-19, it also led to increased depression, anxiety, suicide risk, psychological distress, and decreased vitality. Engagement at a personal level in fundamental daily activities is important to cope with psychological distress. Our results indicate that commitment to fundamental daily activities and following routines is an important protective factor against psychological distress, notwithstanding COVID-19.
    Language English
    Publishing date 2023-09-26
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2563826-9
    ISSN 1664-1078
    ISSN 1664-1078
    DOI 10.3389/fpsyg.2023.1256240
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Dysphagia associated with esophageal wall thickening in patients with nonspecific high-resolution manometry findings: Understanding motility beyond the Chicago classification version 4.0.

    Choi, Jin Young / Jung, Kee Wook / Pandolfino, John E / Choi, Kyungmin / Park, Young Soo / Na, Hee Kyong / Ahn, Ji Yong / Lee, Jeong Hoon / Kim, Do Hoon / Choi, Kee Don / Song, Ho June / Lee, Gin Hyug / Jung, Hwoon-Yong

    Neurogastroenterology and motility

    2024  Volume 36, Issue 4, Page(s) e14736

    Abstract: Background: Previous studies have demonstrated that 50% of patients with normal high-resolution manometry (HRM) findings or ineffective esophageal motility (IEM) may have abnormal functional luminal imaging probe (FLIP) results. However, the specific ... ...

    Abstract Background: Previous studies have demonstrated that 50% of patients with normal high-resolution manometry (HRM) findings or ineffective esophageal motility (IEM) may have abnormal functional luminal imaging probe (FLIP) results. However, the specific HRM findings associated with abnormal FLIP results are unknown. Herein, we investigated the relationship between nonspecific manometry findings and abnormal FLIP results.
    Methods: We retrospectively analyzed 684 patients who underwent HRM at a tertiary care center in Seoul, Korea, based on the Chicago Classification version 4.0 protocol.
    Key results: Among the 684 patients, 398 had normal HRM findings or IEM. Of these 398 patients, eight showed esophageal wall thickening on endoscopic ultrasonography or computed tomography; however, no abnormalities were seen during esophagogastroduodenoscopy. Among these eight patients, seven showed repetitive simultaneous contractions (RSCs) in at least one of the two positions: 61% (±29%) in 10 swallows in the supine position and 51% (±30%) in five swallows in the upright position. Four patients who underwent FLIP had a significantly decreased esophagogastric junction distensibility index (1.0 ± 0.5
    Conclusions & inferences: A subset of patients (2%) with normal HRM findings or IEM and RSCs experienced dysphagia associated with poor distensibility of the thickened esophageal wall. FLIP assessment or combined HRM and impedance protocols may help better define these patients who may respond well to POEM.
    MeSH term(s) Humans ; Deglutition Disorders/diagnosis ; Esophageal Motility Disorders/complications ; Esophageal Motility Disorders/diagnosis ; Esophageal Motility Disorders/pathology ; Retrospective Studies ; Manometry/methods
    Language English
    Publishing date 2024-01-15
    Publishing country England
    Document type Journal Article
    ZDB-ID 1186328-6
    ISSN 1365-2982 ; 1350-1925
    ISSN (online) 1365-2982
    ISSN 1350-1925
    DOI 10.1111/nmo.14736
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Clinical outcomes of argon plasma coagulation for the treatment of gastric low grade dysplasia.

    Wang, Hoyoung / Ahn, Ji Yong / Noh, Jin Hee / Na, Hee Kyoung / Jung, Kee Wook / Lee, Jeong Hoon / Kim, Do Hoon / Choi, Kee Don / Song, Ho June / Lee, Gin Hyug / Jung, Hwoon-Yong

    Gastrointestinal endoscopy

    2024  

    Abstract: Background & aims: Argon plasma coagulation (APC) could be considered a treatment modality for small gastric low grade dysplasia (LGD) instead of endoscopic resection (ER). Our study investigated the clinical outcomes of APC for treating gastric LGD and ...

    Abstract Background & aims: Argon plasma coagulation (APC) could be considered a treatment modality for small gastric low grade dysplasia (LGD) instead of endoscopic resection (ER). Our study investigated the clinical outcomes of APC for treating gastric LGD and associated variables with local recurrence.
    Methods: This study included 911 patients who underwent APC for gastric neoplasms at the tertiary hospital from July 2007 to March 2022 with a minimal follow-up of 12 months. 112 subjects without any information about H. pylori infection status, 164 subjects who underwent APC for salvage therapy, 5 subjects with high grade dysplasia, and 12 subjects with cancer were excluded. Through a retrospective review of medical data, the clinical outcomes and variables associated with the local recurrence were analyzed.
    Results: A total of 618 patients with LGD (median age of 64 years old) were followed up for a median of 30 months and local recurrence has happened in 21 patients (3.4%). Multivariate analysis showed lesion size (hazard ratio 1.06, 95% confidential interval 1.01-1.12) was associated with the local recurrence. Among 557 lesions smaller than 10 mm, local recurrence was found in 14 cases (2.6%) and local recurrence was in 7 cases (9.5%) of 109 tumors larger than 10 mm (p <0.004).
    Conclusions: In gastric LGD smaller than 10 mm without scars, APC is a good treatment modality in place of ER. However, when a lesion is larger, APC should be selected carefully with close monitoring.
    Language English
    Publishing date 2024-01-23
    Publishing country United States
    Document type Journal Article
    ZDB-ID 391583-9
    ISSN 1097-6779 ; 0016-5107
    ISSN (online) 1097-6779
    ISSN 0016-5107
    DOI 10.1016/j.gie.2024.01.025
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Natural history of gastric leiomyoma.

    Park, Kwangbeom / Ahn, Ji Yong / Na, Hee Kyong / Jung, Kee Wook / Lee, Jeong Hoon / Kim, Do Hoon / Choi, Kee Don / Song, Ho June / Lee, Gin Hyug / Jung, Hwwon-Yong

    Surgical endoscopy

    2024  

    Abstract: Background: Most gastric leiomyomas are asymptomatic and benign subepithelial tumors (SETs); however, some may increase in size or become symptomatic. Understanding their natural history is therefore important to their management. We investigated the ... ...

    Abstract Background: Most gastric leiomyomas are asymptomatic and benign subepithelial tumors (SETs); however, some may increase in size or become symptomatic. Understanding their natural history is therefore important to their management. We investigated the natural history of histologically proven gastric leiomyomas.
    Methods: We retrospectively reviewed histologically proven gastric leiomyoma cases at a tertiary center. The baseline characteristics of these cases were analyzed, and those with a follow-up period of at least 12 months without immediate resection were evaluated. The primary outcome was the frequency of size increase of more than 25% during the follow-up period, and the secondary outcome was the histopathologic results in cases that underwent resection.
    Results: Among the 231 patients with histologically proven gastric leiomyomas, the most frequent location was the cardia (77.1%), and the median size was 3 cm (IQR 2-4 cm). Eighty-four cases were followed up over a median period of 50.8 months (IQR 27.2-91.3 months). During the follow-up period, tumor size increased in two cases (2.4%). Surgical results showed that one case was leiomyoma, and the other was leiomyosarcoma. Among the remaining cases without change in size, 15 underwent surgical resection (n = 10) or endoscopic resection (n = 5), and all cases were confirmed as leiomyoma.
    Conclusions: Most gastric leiomyomas are benign SETs, and an increase in size is not frequent, even in large-sized cases. Close monitoring with routine follow-up without resection may be sufficient in cases of histologically proven gastric leiomyoma. However, in cases of ulceration or size increase, resection may be beneficial.
    Language English
    Publishing date 2024-03-26
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 639039-0
    ISSN 1432-2218 ; 0930-2794
    ISSN (online) 1432-2218
    ISSN 0930-2794
    DOI 10.1007/s00464-024-10782-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Deep learning approach to detection of colonoscopic information from unstructured reports.

    Seong, Donghyeong / Choi, Yoon Ho / Shin, Soo-Yong / Yi, Byoung-Kee

    BMC medical informatics and decision making

    2023  Volume 23, Issue 1, Page(s) 28

    Abstract: Background: Colorectal cancer is a leading cause of cancer deaths. Several screening tests, such as colonoscopy, can be used to find polyps or colorectal cancer. Colonoscopy reports are often written in unstructured narrative text. The information ... ...

    Abstract Background: Colorectal cancer is a leading cause of cancer deaths. Several screening tests, such as colonoscopy, can be used to find polyps or colorectal cancer. Colonoscopy reports are often written in unstructured narrative text. The information embedded in the reports can be used for various purposes, including colorectal cancer risk prediction, follow-up recommendation, and quality measurement. However, the availability and accessibility of unstructured text data are still insufficient despite the large amounts of accumulated data. We aimed to develop and apply deep learning-based natural language processing (NLP) methods to detect colonoscopic information.
    Methods: This study applied several deep learning-based NLP models to colonoscopy reports. Approximately 280,668 colonoscopy reports were extracted from the clinical data warehouse of Samsung Medical Center. For 5,000 reports, procedural information and colonoscopic findings were manually annotated with 17 labels. We compared the long short-term memory (LSTM) and BioBERT model to select the one with the best performance for colonoscopy reports, which was the bidirectional LSTM with conditional random fields. Then, we applied pre-trained word embedding using large unlabeled data (280,668 reports) to the selected model.
    Results: The NLP model with pre-trained word embedding performed better for most labels than the model with one-hot encoding. The F1 scores for colonoscopic findings were: 0.9564 for lesions, 0.9722 for locations, 0.9809 for shapes, 0.9720 for colors, 0.9862 for sizes, and 0.9717 for numbers.
    Conclusions: This study applied deep learning-based clinical NLP models to extract meaningful information from colonoscopy reports. The method in this study achieved promising results that demonstrate it can be applied to various practical purposes.
    MeSH term(s) Humans ; Deep Learning ; Colonoscopy ; Natural Language Processing ; Data Warehousing ; Colorectal Neoplasms
    Language English
    Publishing date 2023-02-07
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2046490-3
    ISSN 1472-6947 ; 1472-6947
    ISSN (online) 1472-6947
    ISSN 1472-6947
    DOI 10.1186/s12911-023-02121-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Virulence Traits and Azole Resistance in Korean

    Byun, Seung A / Kwon, Yong Jun / Lee, Ga Yeong / Choi, Min Ji / Jeong, Seok Hoon / Kim, Dokyun / Choi, Min Hyuk / Kee, Seung-Jung / Kim, Soo Hyun / Shin, Myung Geun / Won, Eun Jeong / Shin, Jong Hee

    Journal of fungi (Basel, Switzerland)

    2023  Volume 9, Issue 10

    Abstract: We analyzed the virulence traits and azole resistance mechanisms of ... ...

    Abstract We analyzed the virulence traits and azole resistance mechanisms of 104
    Language English
    Publishing date 2023-09-28
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2784229-0
    ISSN 2309-608X ; 2309-608X
    ISSN (online) 2309-608X
    ISSN 2309-608X
    DOI 10.3390/jof9100979
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Efficacy and safety of once-daily carvedilol in atrial fibrillation patients: a randomized, double-blind, placebo-controlled trial.

    Choi, Jong-Il / Park, Yae Min / Oh, Yong-Seog / Kim, Jin-Bae / Han, Seongwook / Park, Jong-Sung / On, Young Keun / Choi, Kee-Joon / Hwang, Gyo-Seung / Lee, Moon-Hyoung / Shin, Dong-Gu / Kim, Nam-Ho / Kim, Dae-Kyeong / Namgung, June / Kim, Dae-Hyeok / Park, Hyung-Wook / Park, Hwan-Cheol / Choi, Eue-Keun / Rhee, Kyoung Suk /
    Shin, Seung Yong / Kim, Young-Hoon

    Heart rhythm

    2024  

    Language English
    Publishing date 2024-04-13
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2229357-7
    ISSN 1556-3871 ; 1547-5271
    ISSN (online) 1556-3871
    ISSN 1547-5271
    DOI 10.1016/j.hrthm.2024.04.057
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Whole-Genome Sequence Analysis of

    Lim, Ha Jin / Choi, Min Ji / Byun, Seung A / Won, Eun Jeong / Park, Joo Heon / Choi, Yong Jun / Choi, Hyun-Jung / Choi, Hyun-Woo / Kee, Seung-Jung / Kim, Soo Hyun / Shin, Myung Geun / Lee, Seung Yeob / Kim, Mi-Na / Shin, Jong Hee

    Journal of fungi (Basel, Switzerland)

    2023  Volume 9, Issue 5

    Abstract: Whole-genome sequencing (WGS) was used to determine the molecular mechanisms of multidrug resistance for 10 ... ...

    Abstract Whole-genome sequencing (WGS) was used to determine the molecular mechanisms of multidrug resistance for 10 serial
    Language English
    Publishing date 2023-04-26
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2784229-0
    ISSN 2309-608X ; 2309-608X
    ISSN (online) 2309-608X
    ISSN 2309-608X
    DOI 10.3390/jof9050515
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Incidental versus symptomatic pulmonary embolism in patients without cancer.

    Lee, Yong Hoon / Cha, Seung-Ick / Park, Jongmin / Lim, Jae Kwang / Lee, Won Kee / Park, Ji-Eun / Choi, Sun Ha / Seo, Hyewon / Yoo, Seung-Soo / Lee, Shin-Yup / Lee, Jaehee / Kim, Chang-Ho / Park, Jae-Yong

    Vascular medicine (London, England)

    2023  Volume 28, Issue 5, Page(s) 461–462

    MeSH term(s) Humans ; Pulmonary Embolism/diagnosis ; Neoplasms/complications ; Neoplasms/diagnosis ; Neoplasms/epidemiology ; Incidental Findings
    Language English
    Publishing date 2023-05-19
    Publishing country England
    Document type Letter
    ZDB-ID 1311628-9
    ISSN 1477-0377 ; 1358-863X
    ISSN (online) 1477-0377
    ISSN 1358-863X
    DOI 10.1177/1358863X231171614
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Endothelial GABA signaling: a phoenix awakened.

    Choi, Yong Kee / Vasudevan, Anju

    Aging

    2018  Volume 10, Issue 5, Page(s) 859–860

    MeSH term(s) Animals ; Brain/metabolism ; Endothelial Cells/metabolism ; Humans ; Signal Transduction/physiology ; gamma-Aminobutyric Acid/metabolism
    Chemical Substances gamma-Aminobutyric Acid (56-12-2)
    Language English
    Publishing date 2018-05-30
    Publishing country United States
    Document type Editorial ; Research Support, N.I.H., Extramural
    ISSN 1945-4589
    ISSN (online) 1945-4589
    DOI 10.18632/aging.101457
    Database MEDical Literature Analysis and Retrieval System OnLINE

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