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  1. Article: Porcine Epidemic Diarrhea: Insights and Progress on Vaccines.

    Park, Jung-Eun

    Vaccines

    2024  Volume 12, Issue 2

    Abstract: Porcine epidemic diarrhea (PED) is a swine-wasting disease caused by coronavirus infection. It causes great economic damage to the swine industry worldwide. Despite the continued use of vaccines, PED outbreaks continue, highlighting the need to review ... ...

    Abstract Porcine epidemic diarrhea (PED) is a swine-wasting disease caused by coronavirus infection. It causes great economic damage to the swine industry worldwide. Despite the continued use of vaccines, PED outbreaks continue, highlighting the need to review the effectiveness of current vaccines and develop additional vaccines based on new platforms. Here, we review existing vaccine technologies for preventing PED and highlight promising technologies that may help control PED virus in the future.
    Language English
    Publishing date 2024-02-18
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2703319-3
    ISSN 2076-393X
    ISSN 2076-393X
    DOI 10.3390/vaccines12020212
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  2. Article: Less is more: lessons from the COVID-19 pandemic in transfusion strategies after colorectal surgery.

    Park, Eun Jung

    Annals of coloproctology

    2023  Volume 39, Issue 6, Page(s) 445–446

    Language English
    Publishing date 2023-12-28
    Publishing country Korea (South)
    Document type Editorial
    ZDB-ID 2711906-3
    ISSN 2287-9722 ; 2287-9714
    ISSN (online) 2287-9722
    ISSN 2287-9714
    DOI 10.3393/ac.2023.00878.0125
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  3. Article ; Online: Minimum 19-Year Clinical Results and Patient Satisfaction After Total Knee Arthroplasty.

    Kim, Young-Hoo / Park, Jang-Won / Jang, Young-Soo / Kim, Eun-Jung

    The Journal of arthroplasty

    2024  

    Abstract: Background: Long-term (minimum 19-year) outcome data on clinical results and patient satisfaction after posterior-stabilized total knee arthroplasties (TKAs) are missing in the literature. The purpose of the study was to evaluate the clinical and ... ...

    Abstract Background: Long-term (minimum 19-year) outcome data on clinical results and patient satisfaction after posterior-stabilized total knee arthroplasties (TKAs) are missing in the literature. The purpose of the study was to evaluate the clinical and radiographic results as well as patient satisfaction at a mean of 21.2 years after posterior-stabilized TKAs.
    Methods: This study included 756 patients (1,350 knees) who had undergone TKAs. There were 96 men and 660 women (mean age, 58 years; range, 40 to 84). The mean follow-up was 21.2 years (range, 19 to 23). At each follow-up visit, the patients were assessed radiographically and clinically. Furthermore, patient satisfaction was determined.
    Results: The Knee Society total, pain, function, and deformity scores were 42, 18, 33, and 5 points, respectively, at the final follow-up. The mean Western Ontario and McMaster Universities Arthritis Index score was 25 points at the final follow-up. With revision or aseptic loosening as the end point, the 23-year intimated survival for the implant was 96% (95% confidence interval, 91 to 100%). The overall patient satisfaction score at the final follow-up was 83.3 points (range, 81 to 86). Patient satisfaction scores with regard to pain, housework, recreation, and surgery were 84, 81, 82, and 86 points, respectively.
    Conclusions: The findings of the present, mean 21-year follow-up clinical study suggest excellent results with regard to the revision rates and survivorship of the posterior-stabilized total knee implants. However, consistent with the literature, we found that about 80% of patients expressed overall satisfaction with their primary TKAs. About 8% of patients were either somewhat or very dissatisfied with the procedure.
    Language English
    Publishing date 2024-03-16
    Publishing country United States
    Document type Journal Article
    ZDB-ID 632770-9
    ISSN 1532-8406 ; 0883-5403
    ISSN (online) 1532-8406
    ISSN 0883-5403
    DOI 10.1016/j.arth.2024.03.021
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2134: Show issues Location:
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  4. Article: Multi-Organ Nutrigenomic Effects of Dietary Grapes in a Mouse Model.

    Dave, Asim / Park, Eun-Jung / Pezzuto, John M

    Antioxidants (Basel, Switzerland)

    2023  Volume 12, Issue 10

    Abstract: As a whole food, the potential health benefits of table grapes have been widely studied. Some individual constituents have garnered great attention, particularly resveratrol, but normal quantities in the diet are meniscal. On the other hand, the grape ... ...

    Abstract As a whole food, the potential health benefits of table grapes have been widely studied. Some individual constituents have garnered great attention, particularly resveratrol, but normal quantities in the diet are meniscal. On the other hand, the grape contains hundreds of compounds, many of which have antioxidant potential. Nonetheless, the achievement of serum or tissue concentrations of grape antioxidants sufficient to mediate a direct quenching effect is not likely, which supports the idea of biological responses being mediated by an indirect catalytic-type response. We demonstrate herein with Hsd:ICR (CD-1
    Language English
    Publishing date 2023-10-01
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2704216-9
    ISSN 2076-3921
    ISSN 2076-3921
    DOI 10.3390/antiox12101821
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  5. Article ; Online: Effect of high hydrostatic pressure treatment on the inactivation and sublethal injury of foodborne pathogens and quality of apple puree at different pH.

    Lee, Eun-Jung / Kim, Soo-Hwan / Park, Sang-Hyun

    Food microbiology

    2023  Volume 114, Page(s) 104302

    Abstract: The objectives of this study were to evaluate the survival of high hydrostatic pressure (HHP)-treated Salmonella Typhimurium, Escherichia coli O157:H7, and Listeria monocytogenes in apple puree, as well as to determine the levels of HHP-induced cell ... ...

    Abstract The objectives of this study were to evaluate the survival of high hydrostatic pressure (HHP)-treated Salmonella Typhimurium, Escherichia coli O157:H7, and Listeria monocytogenes in apple puree, as well as to determine the levels of HHP-induced cell injury according to the pressure level, holding time, and pH of apple puree. Apple puree was inoculated with three foodborne pathogens and treated at pressures of 300-600 MPa for up to 7 min at 22 °C using HHP equipment. Increasing the pressure level and lowering the pH of apple puree led to larger microbial reductions, and E. coli O157:H7 showed higher resistance compared to S. Typhimurium and L. monocytogenes. Besides, approximately 5-log injured cells of E. coli O157:H7 were induced in apple puree at pH 3.5 and 3.8. HHP treatment at 500 MPa for 2 min effectively achieved complete inactivation of the three pathogens in apple puree at pH 3.5. For apple puree at pH 3.8, more than 2 min treatment of HHP at 600 MPa is seemingly needed to achieve complete inactivation of the three pathogens. Transmission electron microscopy analysis was conducted to identify ultrastructural changes in the injured or dead cells after HHP treatment. Plasmolysis and uneven cavities in the cytoplasm were observed in injured cells, and additional deformations, such as distorted and rough cell envelopes, and cell disruption occurred in dead cells. No changes in solid soluble content (SSC) and color of apple puree were observed after HHP treatment, and no differences were detected between control and HHP-treated samples during 10 d of storage at 5 °C. The results of this study could be useful in determining the acidity of apple purees or the treatment time at specific acidity levels when applying the HHP processing.
    MeSH term(s) Hydrostatic Pressure ; Malus ; Food Microbiology ; Escherichia coli O157 ; Listeria monocytogenes ; Hydrogen-Ion Concentration ; Colony Count, Microbial
    Language English
    Publishing date 2023-04-29
    Publishing country England
    Document type Journal Article
    ZDB-ID 50892-5
    ISSN 1095-9998 ; 0740-0020
    ISSN (online) 1095-9998
    ISSN 0740-0020
    DOI 10.1016/j.fm.2023.104302
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4667: Show issues Location:
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  6. Article: Tailoring strategies for colorectal cancer screening and treatment based on age in colorectal cancer patients.

    Park, Eun Jung

    Annals of coloproctology

    2022  Volume 38, Issue 3, Page(s) 181–182

    Language English
    Publishing date 2022-06-27
    Publishing country Korea (South)
    Document type Editorial ; Comment
    ZDB-ID 2711906-3
    ISSN 2287-9722 ; 2287-9714
    ISSN (online) 2287-9722
    ISSN 2287-9714
    DOI 10.3393/ac.2022.00395.0056
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  7. Article: Correction: Oh et al. Enhanced Effect of Polyethyleneimine-Modified Graphene Oxide and Simvastatin on Osteogenic Differentiation of Murine Bone Marrow-Derived Mesenchymal Stem Cells.

    Oh, Jun-Sung / Park, Jeong-Sun / Lee, Eun-Jung

    Biomedicines

    2022  Volume 10, Issue 8

    Abstract: Jeong-Sun Park ...

    Abstract Jeong-Sun Park
    Language English
    Publishing date 2022-07-27
    Publishing country Switzerland
    Document type Published Erratum
    ZDB-ID 2720867-9
    ISSN 2227-9059
    ISSN 2227-9059
    DOI 10.3390/biomedicines10081802
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  8. Article ; Online: CRISPR/Cas9-mediated mutagenesis of rice NAC transcription factor genes results in altered innate immunity.

    Son, Seungmin / Song, Giha / Nam, Suhyeon / Lee, Gunhee / Im, Jeonghui / Lee, Kyong Sil / Park, Yeo Jin / Suh, Eun-Jung / Park, Sang Ryeol

    Plant physiology

    2024  

    Language English
    Publishing date 2024-02-22
    Publishing country United States
    Document type Journal Article
    ZDB-ID 208914-2
    ISSN 1532-2548 ; 0032-0889
    ISSN (online) 1532-2548
    ISSN 0032-0889
    DOI 10.1093/plphys/kiae084
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    In stock of ZB MED Bonn / Germany

    Z 1193: Show issues

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  9. Article ; Online: Adjunctive administration of parabiotic Lactobacillus sakei CVL-001 ameliorates drug-induced toxicity and pulmonary inflammation during antibiotic treatment for tuberculosis.

    Kim, Hagyu / Song, Eun-Jung / Choi, Eunsol / Kwon, Kee Woong / Park, Jong-Hwan / Shin, Sung Jae

    International immunopharmacology

    2024  Volume 132, Page(s) 111937

    Abstract: Tuberculosis (TB) treatment requires a long therapeutic duration and induces adverse effects such as hepatotoxicity, causing discontinuation of treatment. Reduced adherence to TB medications elevates the risk of recurrence and the development of drug ... ...

    Abstract Tuberculosis (TB) treatment requires a long therapeutic duration and induces adverse effects such as hepatotoxicity, causing discontinuation of treatment. Reduced adherence to TB medications elevates the risk of recurrence and the development of drug resistance. Additionally, severe cavitary TB with a high burden of Mycobacterium tuberculosis (Mtb) and inflammation-mediated tissue damage may need an extended treatment duration, resulting in a higher tendency of drug-induced toxicity. We previously reported that the administration of Lactobacillus sakei CVL-001 (L. sakei CVL-001) regulates inflammation and improves mucosal barrier function in a murine colitis model. Since accumulating evidence has reported the functional roles of probiotics in drug-induced liver injury and pulmonary inflammation, we employed a parabiotic form of the L. sakei CVL-001 to investigate whether this supplement may provide beneficial effects on the reduction in drug-induced liver damage and pulmonary inflammation during chemotherapy. Intriguingly, L. sakei CVL-001 administration slightly reduced Mtb burden without affecting lung inflammation and weight loss in both Mtb-resistant and -susceptible mice. Moreover, L. sakei CVL-001 decreased T cell-mediated inflammatory responses and increased regulatory T cells along with an elevated antigen-specific IL-10 production, suggesting that this parabiotic may restrain excessive inflammation during antibiotic treatment. Furthermore, the parabiotic intervention significantly reduced levels of alanine aminotransferase, an indicator of hepatotoxicity, and cell death in liver tissues. Collectively, our data suggest that L. sakei CVL-001 administration has the potential to be an adjunctive therapy by reducing pulmonary inflammation and liver damage during anti-TB drug treatment and may benefit adherence to TB medication in lengthy treatment.
    Language English
    Publishing date 2024-04-02
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2043785-7
    ISSN 1878-1705 ; 1567-5769
    ISSN (online) 1878-1705
    ISSN 1567-5769
    DOI 10.1016/j.intimp.2024.111937
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5408: Show issues Location:
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  10. Article ; Online: Ameliorative Effects of

    Kim, Jong-Yeon / Park, Eun-Jung / Lee, Hae-Jeung

    International journal of molecular sciences

    2022  Volume 23, Issue 11

    Abstract: Lactobacillus ... ...

    Abstract Lactobacillus plantarum
    MeSH term(s) 3T3-L1 Cells ; AMP-Activated Protein Kinases/metabolism ; Adipocytes/metabolism ; Adipogenesis/genetics ; Animals ; Cell Differentiation ; Lactobacillus plantarum/metabolism ; Lipid Metabolism ; Lipids/pharmacology ; Mice ; PPAR gamma/genetics ; PPAR gamma/metabolism
    Chemical Substances Lipids ; PPAR gamma ; AMP-Activated Protein Kinases (EC 2.7.11.31)
    Language English
    Publishing date 2022-05-24
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms23115901
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