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  1. Article: Aluminum as a risk factor for Alzheimer's disease.

    Ferreira, Pricilla Costa / Piai, Kamila de Almeida / Takayanagui, Angela Maria Magosso / Segura-Muñoz, Susana Inés

    Revista latino-americana de enfermagem

    2008  Volume 16, Issue 1, Page(s) 151–157

    Abstract: The purpose of the study was to condense existing scientific evidence about the relation between aluminum (Al) exposure and risk for the development of Alzheimer's Disease (AD), evaluating its long-term effects on the population's health. A systematic ... ...

    Abstract The purpose of the study was to condense existing scientific evidence about the relation between aluminum (Al) exposure and risk for the development of Alzheimer's Disease (AD), evaluating its long-term effects on the population's health. A systematic literature review was carried out in two databases, MEDLINE and LILACS, between 1990 and 2005, using the uniterms: "Aluminum exposure and Alzheimer Disease" and "Aluminum and risk for Alzheimer Disease". After application of the Relevance Test, 34 studies were selected, among which 68% established a relation between Al and AD, 23.5% were inconclusive and 8.5% did not establish a relation between Al and AD. Results showed that Al is associated to several neurophysiologic processes that are responsible for the characteristic degeneration of AD. In spite of existing polemics all over the world about the role of Al as a risk factor for AD, in recent years, scientific evidence has demonstrated that Al is associated with the development of AD.
    MeSH term(s) Aluminum/adverse effects ; Alzheimer Disease/chemically induced ; Humans ; Risk Factors
    Chemical Substances Aluminum (CPD4NFA903)
    Language English
    Publishing date 2008-04-02
    Publishing country Brazil
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Review ; Systematic Review
    ZDB-ID 2105698-5
    ISSN 1518-8345 ; 0104-1169
    ISSN (online) 1518-8345
    ISSN 0104-1169
    DOI 10.1590/s0104-11692008000100023
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Combining diagnostic procedures for the management of leishmaniasis in areas with high prevalence of Leishmania guyanensis.

    Benicio, Ednelza de Almeida / Gadelha, Ellen Pricilla Nunes / Talhari, Anette / Silva, Roberto Moreira da / Ferreira, Luis Carlos / Santos, Mayara Cristina Cordeiro dos / Mira, Marcelo Távora / Oliveira, Cintia Mara Costa de / Talhari, Carolina / Talhari, Sinésio / Machado, Paulo Roberto / Schriefer, Albert

    Anais brasileiros de dermatologia

    2012  Volume 86, Issue 6, Page(s) 1141–1144

    Abstract: Background: The Amazon region corresponds to approximately 40% of the cases of leishmaniasis in Brazil. We report a prospective study with 180 patients conducted in a health care unit that diagnoses 10% of the cases of leishmaniasis in the Brazilian ... ...

    Abstract Background: The Amazon region corresponds to approximately 40% of the cases of leishmaniasis in Brazil. We report a prospective study with 180 patients conducted in a health care unit that diagnoses 10% of the cases of leishmaniasis in the Brazilian Amazon. The study addresses how a combination of procedures improves diagnosis in areas with high prevalence of Leishmania guyanensis.
    Objectives: to evaluate diagnostic methods in areas with high prevalence of Leishmania guyanensis.
    Methods: All subjects were amastigote-positive by direct microscopic examination of lesion scarifications. We conducted skin biopsy and histopathology, polymerase chain reaction and parasite cultivation.
    Results: Polymerase chain reaction detected almost ninety percent of infections when two amplification protocols were used (mini-exon and HSP-70). HSP-70 specific polymerase chain reaction matched the sensitivity of parasite cultivation plus histopathology.
    Conclusion: The best combination was polymerase chain reaction plus histopathology, which increased diagnostic sensitivity to 94%. Species discrimination by polymerase chain reaction disclosed prevalence of human infections with Leishmania guyanensis of 94% and with Leishmania braziliensis of 6% for this region.
    MeSH term(s) Adolescent ; Adult ; Aged ; Biopsy ; Brazil ; Child ; Child, Preschool ; Female ; Humans ; Leishmania braziliensis/isolation & purification ; Leishmania guyanensis/isolation & purification ; Leishmaniasis, Mucocutaneous/diagnosis ; Male ; Middle Aged ; Polymerase Chain Reaction ; Prevalence ; Prospective Studies ; Sensitivity and Specificity ; Young Adult
    Language English
    Publishing date 2012-01-15
    Publishing country Spain
    Document type Evaluation Studies ; Journal Article
    ZDB-ID 433655-0
    ISSN 1806-4841 ; 0365-0596
    ISSN (online) 1806-4841
    ISSN 0365-0596
    DOI 10.1590/s0365-05962011000600012
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 359: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 344: Show issues

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  3. Article ; Online: Aluminum concentrations in water of elderly people's houses and retirement homes and its relation with elderly health.

    Ferreira, Pricilla Costa / Tonani, Karina A de Abreu / Julião, Fabiana C / Cupo, Palmira / Domingo, José L / Segura-Muñoz, Susana Inés

    Bulletin of environmental contamination and toxicology

    2009  Volume 83, Issue 4, Page(s) 565–569

    Abstract: The purpose of this study was to determine the concentrations of aluminum (Al) and other metals in water samples from elderly people's houses and retirement homes. Forty-six duplicate water samples from kitchen taps were collected in Ribeirão Preto/SP, ... ...

    Abstract The purpose of this study was to determine the concentrations of aluminum (Al) and other metals in water samples from elderly people's houses and retirement homes. Forty-six duplicate water samples from kitchen taps were collected in Ribeirão Preto/SP, Brazil. Metal levels were measured by atomic absorption spectrophotometer. Aluminum concentration exceeded the maximum allowed values in 26% of samples according to the Decree 518/2004 of the Brazilian Health Ministry. It was noted that 11% of elderly living at monitored houses, as well as 19% living at retirement homes presented Alzheimer disease diagnostic. These results suggest taking into account Al risks among vulnerable elderly population groups.
    MeSH term(s) Aged ; Aluminum/analysis ; Alzheimer Disease/epidemiology ; Brazil/epidemiology ; Environmental Monitoring ; Epidemiological Monitoring ; Housing for the Elderly ; Humans ; Metals, Heavy/analysis ; Middle Aged ; Water Supply/standards
    Chemical Substances Metals, Heavy ; Aluminum (CPD4NFA903)
    Language English
    Publishing date 2009-10
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 6895-0
    ISSN 1432-0800 ; 0007-4861
    ISSN (online) 1432-0800
    ISSN 0007-4861
    DOI 10.1007/s00128-009-9791-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 75: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  4. Article ; Online: Aluminum as a risk factor for Alzheimer's disease Aluminio como factor de riesgo para la enfermedad de Alzheimer Alumínio como fator de risco para a doença de Alzheimer

    Pricilla Costa Ferreira / Kamila de Almeida Piai / Angela Maria Magosso Takayanagui / Susana Inés Segura-Muñoz

    Revista Latino-Americana de Enfermagem, Vol 16, Iss 1, Pp 151-

    2008  Volume 157

    Abstract: The purpose of the study was to condense existing scientific evidence about the relation between aluminum (Al) exposure and risk for the development of Alzheimer's Disease (AD), evaluating its long-term effects on the population's health. A systematic ... ...

    Abstract The purpose of the study was to condense existing scientific evidence about the relation between aluminum (Al) exposure and risk for the development of Alzheimer's Disease (AD), evaluating its long-term effects on the population's health. A systematic literature review was carried out in two databases, MEDLINE and LILACS, between 1990 and 2005, using the uniterms: "Aluminum exposure and Alzheimer Disease" and "Aluminum and risk for Alzheimer Disease". After application of the Relevance Test, 34 studies were selected, among which 68% established a relation between Al and AD, 23.5% were inconclusive and 8.5% did not establish a relation between Al and AD. Results showed that Al is associated to several neurophysiologic processes that are responsible for the characteristic degeneration of AD. In spite of existing polemics all over the world about the role of Al as a risk factor for AD, in recent years, scientific evidence has demonstrated that Al is associated with the development of AD. El objetivo del estudio fue condensar la evidencia científica existente entre la exposición al aluminio (Al) y el riesgo para el desarrollo de la Enfermedad de Alzheimer (EA), evaluando los efectos para la salud de la población a largo plazo. Una revisión sistemática de la literatura científica existente entre 1990 y 2005, fue realizada en dos bases de datos, MEDLINE y LILACS, utilizando los unitermos: "Aluminium exposure and Alzheimer Disease" y "Aluminium and risk for Alzheimer Disease". Fueron seleccionados 34 trabajos para la investigación, de los cuales 68% establecieron relação entre el Al y la EA, 23,5% no presentaron datos conclusivos y 8,5% no establecieron ninguna relación entre el Al y la EA. A partir de los resultados obtenidos, se verifica que el Al interviene en diversos procesos neurofisiológicos responsables por la degeneración característica de la EA. A pesar de la polémica existente en el médio científico, la evidencia científica demuestra a lo largo de los últimos años que el Al es uno de los determinantes para el desenvolvimiento de la EA. O objetivo do estudo foi condensar a evidência científica existente entre a exposição ao alumínio (Al) e risco para o desenvolvimento da doença de Alzheimer (DA), avaliando os efeitos para saúde da população, a longo prazo. Realizou-se revisão sistemática de literatura produzida entre 1990 e 2005, conduzida em duas bases de dados, MEDLINE e LILACS, utilizando os unitermos: "Aluminium exposure and Alzheimer Disease" e "Aluminium and risk for Alzheimer Disease". Foram selecionados 34 trabalhos para a pesquisa, desses, 68% estabeleceram relação entre o Al e a DA, 23,5% não apresentaram dados conclusivos e 8,5% não estabeleceram nenhuma relação entre o Al e DA. A partir dos resultados obtidos, verifica-se que o Al intervém em diversos processos neurofisiológicos responsáveis pela degeneração característica da DA. Apesar da polêmica existente, a evidência científica demonstra, ao longo dos últimos anos, que o Al se associa com o desenvolvimento da DA.
    Keywords enfermedad de Alzheimer ; alumínio ; factores de riesgo ; doença de Alzheimer ; fatores de risco ; Alzheimer disease ; aluminum ; risk factors ; Nursing ; RT1-120 ; Medicine ; R ; DOAJ:Nursing ; DOAJ:Health Sciences
    Language Portuguese
    Publishing date 2008-02-01T00:00:00Z
    Publisher Escola de Enfermagem de Ribeirão Preto / Universidade de São Paulo
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article: Aluminum Concentrations in Water of Elderly People's Houses and Retirement Homes and Its Relation with Elderly Health

    Ferreira, Pricilla Costa / de Abreu Tonani, Karina A / Julião, Fabiana C / Cupo, Palmira / Domingo, José L / Segura-Muñoz, Susana Inés

    Bulletin of environmental contamination and toxicology. 2009 Oct., v. 83, no. 4

    2009  

    Abstract: The purpose of this study was to determine the concentrations of aluminum (Al) and other metals in water samples from elderly people's houses and retirement homes. Forty-six duplicate water samples from kitchen taps were collected in Ribeirão Preto/SP, ... ...

    Abstract The purpose of this study was to determine the concentrations of aluminum (Al) and other metals in water samples from elderly people's houses and retirement homes. Forty-six duplicate water samples from kitchen taps were collected in Ribeirão Preto/SP, Brazil. Metal levels were measured by atomic absorption spectrophotometer. Aluminum concentration exceeded the maximum allowed values in 26% of samples according to the Decree 518/2004 of the Brazilian Health Ministry. It was noted that 11% of elderly living at monitored houses, as well as 19% living at retirement homes presented Alzheimer disease diagnostic. These results suggest taking into account Al risks among vulnerable elderly population groups.
    Keywords Alzheimer disease ; aluminum ; atomic absorption spectrometry ; elderly ; people ; retirement communities ; risk
    Language English
    Dates of publication 2009-10
    Size p. 565-569.
    Publisher Springer-Verlag
    Publishing place New York
    Document type Article
    ZDB-ID 6895-0
    ISSN 1432-0800 ; 0007-4861
    ISSN (online) 1432-0800
    ISSN 0007-4861
    DOI 10.1007/s00128-009-9791-8
    Database NAL-Catalogue (AGRICOLA)

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    In stock of ZB MED Bonn / Germany

    Z 4303: Show issues

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  6. Article ; Online: ANALYSIS OF METALS CONTENTS IN DOWSTREAM AND UPSTREAM SANITARY LANDFILL GROUNDWATER COLLECTED SAMPLES, RIBEIRÃO PRETO, BRAZIL

    Kamila de Almeida Piai / Pricilla Costa Ferreira / Tânia Maria Beltramini Trevilato / Susana Inés Segura-Muñoz

    Revista Águas Subterrâneas, Vol 20, Iss

    2006  Volume 1

    Abstract: In Ribeirão Preto (Sao Paulo State, Brazil), a municipal landfill site (MLS) for urban waste disposal has been operating since 1989. It is integrated with the Medical Waste Treatment Plant (Microware System). This study aimed to estimate the metal levels ...

    Abstract In Ribeirão Preto (Sao Paulo State, Brazil), a municipal landfill site (MLS) for urban waste disposal has been operating since 1989. It is integrated with the Medical Waste Treatment Plant (Microware System). This study aimed to estimate the metal levels in groundwater samples collected in downstream and upstream groundwater artesian wells of Ribeirão Preto Sanitary Landfill. It was estimated the presence of Ag+, Al3+, Ba2+, Ca2+, Cd2+, Cr°, Cu°, Mg2+, Mn°, Na+, Pb°, Hg°, K+, Se2- e Zn2+ through Espectrophotometric of Atomic Absorption. The points in upstream presented levels of Al3+, Mn°, Pb° and Se2- higher than the standard established by Regulation 518/2004 of the Ministry of Health, of Brazil, while in downstream points the values of Mn° and Pb° were higher than the allowed limits. A study carried out in 2000, which estimated the levels of Cd2+, Cr°, Cu°, Hg°, Mn°, Pb° and Zn2+ in the MLS area demonstrated Mn° and Pb° levels above the limits allowed by oficial regulations, in soil and sewage. However, groundwater samples collected in 2000 were not contaminated. The results obtained in the present study showed the need to adopt measures to protect the groundwater at the Sanitary Landfill Site Area, considering the detected levels of some metals that can affected the quality of the groundwater.
    Keywords Água Subterrânea ; Metal ; Resíduos sólidos ; River ; lake ; and water-supply engineering (General) ; TC401-506 ; Physical geography ; GB3-5030
    Subject code 550
    Language English
    Publishing date 2006-11-01T00:00:00Z
    Publisher Associação Brasileira de Águas Subterrâneas
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article ; Online: Combining diagnostic procedures for the management of leishmaniasis in areas with high prevalence of Leishmania guyanensis Procedimentos diagnósticos combinados no manejo da leishmaniose em áreas com alta prevalência de Leishmania guyanensis

    Ednelza de Almeida Benicio / Ellen Pricilla Nunes Gadelha / Anette Talhari / Roberto Moreira da Silva Jr / Luis Carlos Ferreira / Mayara Cristina Cordeiro dos Santos / Marcelo Távora Mira / Cintia Mara Costa de Oliveira / Carolina Talhari / Sinésio Talhari / Paulo Roberto Machado / Albert Schriefer

    Anais Brasileiros de Dermatologia, Vol 86, Iss 6, Pp 1141-

    2011  Volume 1144

    Abstract: BACKGROUND: The Amazon region corresponds to approximately 40% of the cases of leishmaniasis in Brazil. We report a prospective study with 180 patients conducted in a health care unit that diagnoses 10% of the cases of leishmaniasis in the Brazilian ... ...

    Abstract BACKGROUND: The Amazon region corresponds to approximately 40% of the cases of leishmaniasis in Brazil. We report a prospective study with 180 patients conducted in a health care unit that diagnoses 10% of the cases of leishmaniasis in the Brazilian Amazon. The study addresses how a combination of procedures improves diagnosis in areas with high prevalence of Leishmania guyanensis. OBJECTIVES: to evaluate diagnostic methods in areas with high prevalence of Leishmania guyanensis. METHODS: All subjects were amastigote-positive by direct microscopic examination of lesion scarifications. We conducted skin biopsy and histopathology, polymerase chain reaction and parasite cultivation. RESULTS: Polymerase chain reaction detected almost ninety percent of infections when two amplification protocols were used (mini-exon and HSP-70). HSP-70 specific polymerase chain reaction matched the sensitivity of parasite cultivation plus histopathology. CONCLUSION: The best combination was polymerase chain reaction plus histopathology, which increased diagnostic sensitivity to 94%. Species discrimination by polymerase chain reaction disclosed prevalence of human infections with Leishmania guyanensis of 94% and with Leishmania braziliensis of 6% for this region FUNDAMENTOS: O Amazonas corresponde a aproximadamente 40% dos casos de leishmaniose do país. Nós reportamos um estudo prospectivo com 180 pacientes de uma unidade de saúde que diagnostica 10% dos casos de leishmaniose da amazônia brasileira, com combinação de métodos diagnóstico em área de alta prevalência de Leishmania guyanensis. OBJETIVOS: avaliar métodos diagnóstico da Leishmaniose em área endêmica para Leishmania Amazonensis. MÉTODOS: Todos os pacientes tiveram exame direto positivo com presença de amastigotas. Foi feita também biópsia cutânea, com realização de exame histológico, reação em cadeia da polimerase e cultura. RESULTADO: A reação em cadeia da polimerase detectou aproximadamente 90% de infecção quando foram usados duas técnicas de amplificação (mini-exon and HSP-70). A reação em cadeia da polimerase com HSP-70 foi mais sensível que a cultura associada à histopatologia. CONCLUSÃO: A melhor combinação foi a reação em cadeia da polimerase com histopatologia, com sensibilidade de 94%. A discrimanação das espécies causadoras de infecção humana nessa região mostrou Leishmania guyanensis em 94% dos casos e Leishmania brasiliensis em 6%
    Keywords Diagnóstico ; Leishmania guyanensis ; Leishmaniose ; Diagnosis ; Leishmaniasis ; Dermatology ; RL1-803 ; Medicine ; R ; DOAJ:Dermatology ; DOAJ:Medicine (General) ; DOAJ:Health Sciences
    Language English
    Publishing date 2011-12-01T00:00:00Z
    Publisher Sociedade Brasileira de Dermatologia
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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