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  1. Book ; Thesis: Bestimmung der effektiven Halbwertszeit bei der Radioiodtherapie benigner Schilddrüsenerkrankungen mit 131Iod unter Berücksichtigung diverser Einflussfaktoren

    Hartmann, Tobias Rupert Cyprian

    2016  

    Author's details vorgelegt von Tobias Rupert Cyprian Hartmann
    Subject code 610
    Language German
    Size 107 Blätter, Illustrationen
    Publishing place Freiburg (Breisgau)
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Dissertation, Albert-Ludwigs-Universität Freiburg (Breisgau), 2016
    Note Im Titel ist "131" hochgestellt.
    HBZ-ID HT019346622
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2017 E 990 order for loan Magazin

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  2. Article ; Online: Use-Case-Oriented Evaluation of Wireless Communication Technologies for Advanced Underground Mining Operations.

    Theissen, Marius / Kern, Leonhard / Hartmann, Tobias / Clausen, Elisabeth

    Sensors (Basel, Switzerland)

    2023  Volume 23, Issue 7

    Abstract: This work aims to give an overview of wireless communication technologies (WCT) for underground applications. Difficulties regarding the harsh mining environment and operational constraints for WCT implementation and use are discussed. Selected ... ...

    Abstract This work aims to give an overview of wireless communication technologies (WCT) for underground applications. Difficulties regarding the harsh mining environment and operational constraints for WCT implementation and use are discussed. Selected technologies are then classified regarding underground mining-specific use cases in advanced mining operations. Use-case-based application categories such as 'automation and teleoperation', 'tracking and tracing' and 'Long-Range Underground Monitoring (LUM)' are defined. The use cases determine requirements for the operational suitability and also quantify evaluation criteria for the evaluation of WCT. The result is a comparison by category of the wireless technologies, which underlines potentials of different technologies for defined use cases, but it can be concluded that the technology always has to be evaluated within the use case and operational constraints.
    Language English
    Publishing date 2023-03-28
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2052857-7
    ISSN 1424-8220 ; 1424-8220
    ISSN (online) 1424-8220
    ISSN 1424-8220
    DOI 10.3390/s23073537
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Book ; Online ; Thesis: Optimierung der Sandimmun® Optoral-Dosierung nach Nierentransplantation

    Lampert, Berenike / Beckurts, Tobias / Benzing, Thomas

    eine pharmakokinetische Untersuchung

    2010  

    Institution Universitätsklinikum Köln / Klinik und Poliklinik für Allgemein-, Viszeral- und Tumorchirurgie
    Author's details vorgelegt von Berenike Lampert, geb. Hartmann ; 1. Berichterstatter: Professor Dr. med. K. T. E. Beckurts, 2. Berichterstatter: Universitätsprofessor Dr. med. T. Benzing ; aus dem Zentrum für Operative Medizin der Universität zu Köln, Klinik und Poliklinik für Allgemein-, Viszeral- und Tumorchirurgie
    Subject code 610
    Language German
    Publishing country Germany
    Document type Book ; Online ; Thesis
    Thesis / German Habilitation thesis Köln, Univ., Diss., 2010
    Note Open Access
    HBZ-ID HT016374879
    DOI 10.4126/38m-000000239
    Database Repository for Life Sciences

    Full text online

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  4. Book ; Thesis: Optimierung der Sandimmun® Optoral-Dosierung nach Nierentransplantation

    Lampert, Berenike / Beckurts, Tobias / Benzing, Thomas

    eine pharmakokinetische Untersuchung

    2010  

    Institution Universitätsklinikum Köln / Klinik und Poliklinik für Allgemein-, Viszeral- und Tumorchirurgie
    Author's details vorgelegt von Berenike Lampert, geb. Hartmann ; 1. Berichterstatter: Professor Dr. med. K. T. E. Beckurts, 2. Berichterstatter: Universitätsprofessor Dr. med. T. Benzing ; aus dem Zentrum für Operative Medizin der Universität zu Köln, Klinik und Poliklinik für Allgemein-, Viszeral- und Tumorchirurgie
    Language German
    Size 64 S. : graph. Darst.
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Köln, Univ., Diss., 2010
    HBZ-ID HT016382151
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2010 D 427 order for loan Magazin

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  5. Book ; Online: Emission data from stoves available on the market at a test facility

    Hartmann, Ingo / Ulbricht, Tobias / Lenz, Volker / Thiel, Christian

    2023  

    Keywords Text ; ddc:333.7
    Language English
    Publishing date 2023-05-22
    Publisher Mendeley Data
    Publishing country de
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Book ; Online: Emission data from stoves available on the market at a test facility

    Hartmann, Ingo / Ulbricht, Tobias / Lenz, Volker / Thiel, Christian

    2023  

    Keywords Text ; ddc:333.7
    Language English
    Publishing date 2023-05-23
    Publisher Mendeley Data
    Publishing country de
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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    Inter-library loan at ZB MED

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  7. Book ; Online ; Thesis: Zusammenhänge zwischen der Lipidhomöostase und den molekularen Mechanismen der Alzheimer Krankheit

    Hubig, Hannah [Verfasser] / Hartmann, Tobias [Akademischer Betreuer]

    2022  

    Author's details Hannah Hubig ; Betreuer: Tobias Hartmann
    Keywords Medizin, Gesundheit ; Medicine, Health
    Subject code sg610
    Language German
    Publisher Saarländische Universitäts- und Landesbibliothek
    Publishing place Saarbrücken
    Document type Book ; Online ; Thesis
    Database Digital theses on the web

    Full text online

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  8. Book ; Online ; Thesis: Über die Regulation der Calcium-Homöostase und den Einfluss von STIM-Proteinen auf die Alzheimer-Pathologie

    Streidenberger, Olga [Verfasser] / Hartmann, Tobias [Akademischer Betreuer]

    2022  

    Author's details Olga Streidenberger ; Betreuer: Tobias Hartmann
    Keywords Naturwissenschaften ; Science
    Subject code sg500
    Language German
    Publisher Saarländische Universitäts- und Landesbibliothek
    Publishing place Saarbrücken
    Document type Book ; Online ; Thesis
    Database Digital theses on the web

    Full text online

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    Inter-library loan at ZB MED

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  9. Article ; Online: Eosinophils, Basophils, and Neutrophils in Bullous Pemphigoid.

    Limberg, Maren M / Weihrauch, Tobias / Gray, Natalie / Ernst, Nancy / Hartmann, Karin / Raap, Ulrike

    Biomolecules

    2023  Volume 13, Issue 7

    Abstract: Bullous pemphigoid (BP) is an autoimmune blistering skin disease, of which the incidence has increased in recent years. BP is characterized by circulating IgG and IgE autoantibodies against the hemidesmosomal proteins BP180 and BP230. Although ... ...

    Abstract Bullous pemphigoid (BP) is an autoimmune blistering skin disease, of which the incidence has increased in recent years. BP is characterized by circulating IgG and IgE autoantibodies against the hemidesmosomal proteins BP180 and BP230. Although autoantibodies trigger inflammatory cascades that lead to blister formation, effector cells and cell-mediated autoimmunity must also be considered as important factors in the pathogenesis of BP. The aim of this review is to outline the current knowledge on the role of eosinophils, basophils, and neutrophils in BP.
    MeSH term(s) Humans ; Pemphigoid, Bullous ; Eosinophils/metabolism ; Neutrophils/pathology ; Basophils/pathology ; Autoantigens/metabolism ; Autoimmune Diseases/pathology ; Autoantibodies
    Chemical Substances Autoantigens ; Autoantibodies
    Language English
    Publishing date 2023-06-21
    Publishing country Switzerland
    Document type Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 2701262-1
    ISSN 2218-273X ; 2218-273X
    ISSN (online) 2218-273X
    ISSN 2218-273X
    DOI 10.3390/biom13071019
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Gemfibrozil-Induced Intracellular Triglyceride Increase in SH-SY5Y, HEK and Calu-3 Cells.

    Bachmann, Cornel Manuel / Janitschke, Daniel / Lauer, Anna Andrea / Erhardt, Tobias / Hartmann, Tobias / Grimm, Marcus Otto Walter / Grimm, Heike Sabine

    International journal of molecular sciences

    2023  Volume 24, Issue 3

    Abstract: Gemfibrozil is a drug that has been used for over 40 years to lower triglycerides in blood. As a ligand for peroxisome proliferative-activated receptor-alpha (PPARα), which is expressed in many tissues, it induces the transcription of numerous genes for ... ...

    Abstract Gemfibrozil is a drug that has been used for over 40 years to lower triglycerides in blood. As a ligand for peroxisome proliferative-activated receptor-alpha (PPARα), which is expressed in many tissues, it induces the transcription of numerous genes for carbohydrate and lipid-metabolism. However, nothing is known about how intracellular lipid-homeostasis and, in particular, triglycerides are affected. As triglycerides are stored in lipid-droplets, which are known to be associated with many diseases, such as Alzheimer's disease, cancer, fatty liver disease and type-2 diabetes, treatment with gemfibrozil could adversely affect these diseases. To address the question whether gemfibrozil also affects intracellular lipid-levels, SH-SY5Y, HEK and Calu-3 cells, representing three different metabolically active organs (brain, lung and kidney), were incubated with gemfibrozil and subsequently analyzed semi-quantitatively by mass-spectrometry. Importantly, all cells showed a strong increase in intracellular triglycerides (SH-SY5Y: 170.3%; HEK: 272.1%; Calu-3: 448.1%), suggesting that the decreased triglyceride-levels might be due to an enhanced cellular uptake. Besides the common intracellular triglyceride increase, a cell-line specific alteration in acylcarnitines are found, suggesting that especially in neuronal cell lines gemfibrozil increases the transport of fatty acids to mitochondria and therefore increases the turnover of fatty acids for the benefit of additional energy supply, which could be important in diseases, such as Alzheimer's disease.
    MeSH term(s) Humans ; Gemfibrozil/pharmacology ; Alzheimer Disease/drug therapy ; Neuroblastoma/drug therapy ; Triglycerides/metabolism ; Fatty Acids ; Hypolipidemic Agents/pharmacology ; Hypolipidemic Agents/therapeutic use
    Chemical Substances Gemfibrozil (Q8X02027X3) ; Triglycerides ; Fatty Acids ; Hypolipidemic Agents
    Language English
    Publishing date 2023-02-03
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms24032972
    Database MEDical Literature Analysis and Retrieval System OnLINE

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