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  1. Article: A young woman with atypical chest pain.

    Ruinemans, G M F / Darmanata, J I / Kraai, M

    Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation

    2015  Volume 13, Issue 2, Page(s) 65–66

    Language English
    Publishing date 2015-02-18
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2211468-3
    ISSN 1876-6250 ; 1568-5888 ; 0929-7456
    ISSN (online) 1876-6250
    ISSN 1568-5888 ; 0929-7456
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  2. Article ; Online: A comparison of rate control and rhythm control in patients with recurrent persistent atrial fibrillation.

    Van Gelder, Isabelle C / Hagens, Vincent E / Bosker, Hans A / Kingma, J Herre / Kamp, Otto / Kingma, Tsjerk / Said, Salah A / Darmanata, Julius I / Timmermans, Alphons J M / Tijssen, Jan G P / Crijns, Harry J G M

    The New England journal of medicine

    2002  Volume 347, Issue 23, Page(s) 1834–1840

    Abstract: Background: Maintenance of sinus rhythm is the main therapeutic goal in patients with atrial fibrillation. However, recurrences of atrial fibrillation and side effects of antiarrhythmic drugs offset the benefits of sinus rhythm. We hypothesized that ... ...

    Abstract Background: Maintenance of sinus rhythm is the main therapeutic goal in patients with atrial fibrillation. However, recurrences of atrial fibrillation and side effects of antiarrhythmic drugs offset the benefits of sinus rhythm. We hypothesized that ventricular rate control is not inferior to the maintenance of sinus rhythm for the treatment of atrial fibrillation.
    Methods: We randomly assigned 522 patients who had persistent atrial fibrillation after a previous electrical cardioversion to receive treatment aimed at rate control or rhythm control. Patients in the rate-control group received oral anticoagulant drugs and rate-slowing medication. Patients in the rhythm-control group underwent serial cardioversions and received antiarrhythmic drugs and oral anticoagulant drugs. The end point was a composite of death from cardiovascular causes, heart failure, thromboembolic complications, bleeding, implantation of a pacemaker, and severe adverse effects of drugs.
    Results: After a mean (+/-SD) of 2.3+/-0.6 years, 39 percent of the 266 patients in the rhythm-control group had sinus rhythm, as compared with 10 percent of the 256 patients in the rate-control group. The primary end point occurred in 44 patients (17.2 percent) in the rate-control group and in 60 (22.6 percent) in the rhythm-control group. The 90 percent (two-sided) upper boundary of the absolute difference in the primary end point was 0.4 percent (the prespecified criterion for noninferiority was 10 percent or less). The distribution of the various components of the primary end point was similar in the rate-control and rhythm-control groups.
    Conclusions: Rate control is not inferior to rhythm control for the prevention of death and morbidity from cardiovascular causes and may be appropriate therapy in patients with a recurrence of persistent atrial fibrillation after electrical cardioversion.
    MeSH term(s) Adrenergic beta-Antagonists/therapeutic use ; Aged ; Anti-Arrhythmia Agents/therapeutic use ; Anticoagulants/therapeutic use ; Atrial Fibrillation/complications ; Atrial Fibrillation/mortality ; Atrial Fibrillation/therapy ; Calcium Channel Blockers/therapeutic use ; Combined Modality Therapy ; Disease-Free Survival ; Electric Countershock ; Female ; Heart Rate ; Humans ; Hypertension/complications ; Male ; Recurrence ; Sex Factors
    Chemical Substances Adrenergic beta-Antagonists ; Anti-Arrhythmia Agents ; Anticoagulants ; Calcium Channel Blockers
    Language English
    Publishing date 2002-12-05
    Publishing country United States
    Document type Clinical Trial ; Comparative Study ; Journal Article ; Multicenter Study ; Randomized Controlled Trial ; Research Support, Non-U.S. Gov't
    ZDB-ID 207154-x
    ISSN 1533-4406 ; 0028-4793
    ISSN (online) 1533-4406
    ISSN 0028-4793
    DOI 10.1056/NEJMoa021375
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Pulmonary gallium-67 uptake in amiodarone pneumonitis.

    van Rooij, W J / van der Meer, S C / van Royen, E A / van Zandwijk, N / Darmanata, J I

    Journal of nuclear medicine : official publication, Society of Nuclear Medicine

    1984  Volume 25, Issue 2, Page(s) 211–213

    Abstract: Three patients are presented suffering from interstitial pneumonitis caused by amiodarone. Pulmonary Ga-67 uptake occurred in all three. There appeared to be a discrepancy between the scintigraphic and radiographic findings in two patients. Gallium-67 ... ...

    Abstract Three patients are presented suffering from interstitial pneumonitis caused by amiodarone. Pulmonary Ga-67 uptake occurred in all three. There appeared to be a discrepancy between the scintigraphic and radiographic findings in two patients. Gallium-67 lung scintigraphy may offer an early, sensitive indicator for amiodarone pneumonitis.
    MeSH term(s) Aged ; Amiodarone/adverse effects ; Benzofurans/adverse effects ; Gallium Radioisotopes ; Humans ; Lung/diagnostic imaging ; Male ; Middle Aged ; Pulmonary Fibrosis/chemically induced ; Pulmonary Fibrosis/diagnostic imaging ; Radiography ; Radionuclide Imaging
    Chemical Substances Benzofurans ; Gallium Radioisotopes ; Amiodarone (N3RQ532IUT)
    Language English
    Publishing date 1984-02
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 80272-4
    ISSN 1535-5667 ; 0161-5505 ; 0097-9058 ; 0022-3123
    ISSN (online) 1535-5667
    ISSN 0161-5505 ; 0097-9058 ; 0022-3123
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.MO 328: Show issues

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  4. Article: Amiodarone pneumonitis.

    van Zandwijk, N / Darmanata, J I / Düren, D R / Alberts, C / Durrer, D / Wagenvoort, C A

    European journal of respiratory diseases

    1983  Volume 64, Issue 4, Page(s) 313–317

    MeSH term(s) Amiodarone/adverse effects ; Arrhythmias, Cardiac/chemically induced ; Benzofurans/adverse effects ; Humans ; Male ; Middle Aged ; Pneumonia/chemically induced ; Tachycardia/chemically induced
    Chemical Substances Benzofurans ; Amiodarone (N3RQ532IUT)
    Language English
    Publishing date 1983-05
    Publishing country Denmark
    Document type Case Reports ; Journal Article
    ZDB-ID 759910-9
    ISSN 0106-4339
    ISSN 0106-4339
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  5. Article: Longafwijkingen in interstitium en alveoli na behandeling met amiodaron.

    van Rooy, W J / van der Meer, S C / Darmanata, J L / van Zandwijk, N / van Royen, E A

    Nederlands tijdschrift voor geneeskunde

    1984  Volume 128, Issue 2, Page(s) 85–86

    Title translation Lung abnormalities in interstitium and alveoli following treatment with amiodarone.
    MeSH term(s) Amiodarone/adverse effects ; Benzofurans/adverse effects ; Gallium Radioisotopes ; Humans ; Pulmonary Fibrosis/chemically induced ; Pulmonary Fibrosis/diagnostic imaging ; Radionuclide Imaging
    Chemical Substances Benzofurans ; Gallium Radioisotopes ; Amiodarone (N3RQ532IUT)
    Language Dutch
    Publishing date 1984-01-14
    Publishing country Netherlands
    Document type Letter
    ZDB-ID 82073-8
    ISSN 1876-8784 ; 0028-2162
    ISSN (online) 1876-8784
    ISSN 0028-2162
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  6. Article: Amiodarone pneumonitis: three further cases with a review of published reports.

    Darmanata, J I / van Zandwijk, N / Düren, D R / van Royen, E A / Mooi, W J / Plomp, T A / Jansen, H M / Durrer, D

    Thorax

    1984  Volume 39, Issue 1, Page(s) 57–64

    Abstract: Three further patients are presented who developed evidence of a parenchymal pulmonary disturbance in the course of treatment with amiodarone. In one case the progress of the condition was rapid and ended fatally. Histological examination of the lungs ... ...

    Abstract Three further patients are presented who developed evidence of a parenchymal pulmonary disturbance in the course of treatment with amiodarone. In one case the progress of the condition was rapid and ended fatally. Histological examination of the lungs showed evidence of diffuse alveolar damage. The concentration of amiodarone was from four to seven times higher in the lungs than in other organs studied. The concentration of the metabolite desethylamiodarone in the lungs was even higher in relation to other organs studied. The remaining two patients showed a more insidious onset and improvement after withdrawal of amiodarone and treatment with corticosteroids. Gallium 67 scintigraphy appeared to be a sensitive indicator of this adverse effect. Review of published reports revealed 35 cases of amiodarone pneumonitis, including the cases reported in this study. In 11 instances the dose of amiodarone was 400 mg or less. The onset was either insidious or rapidly progressive. Exertional dyspnoea was always present and a nonproductive cough, hypoxaemia, a raised erythrocyte sedimentation rate and diminished carbon monoxide diffusing capacity (transfer factor) were usually noted. Chest radiographs showed either a reticular pattern or diffuse patchy alveolar infiltrates. Discontinuation of amiodarone and an institution of corticosteroid treatment was usually followed by improvement or resolution.
    MeSH term(s) Adult ; Aged ; Amiodarone/adverse effects ; Benzofurans/adverse effects ; Female ; Gallium Radioisotopes ; Humans ; Lung/diagnostic imaging ; Lung/pathology ; Male ; Middle Aged ; Pneumonia/chemically induced ; Pneumonia/diagnostic imaging ; Pneumonia/pathology ; Prednisolone/therapeutic use ; Radionuclide Imaging
    Chemical Substances Benzofurans ; Gallium Radioisotopes ; Prednisolone (9PHQ9Y1OLM) ; Amiodarone (N3RQ532IUT)
    Language English
    Publishing date 1984-01
    Publishing country England
    Document type Case Reports ; Journal Article
    ZDB-ID 204353-1
    ISSN 1468-3296 ; 0040-6376
    ISSN (online) 1468-3296
    ISSN 0040-6376
    DOI 10.1136/thx.39.1.57
    Database MEDical Literature Analysis and Retrieval System OnLINE

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