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  1. Article: Welchen Stellenwert haben Atypika heute? Interview mit Dr. Stefan Leucht, München

    Leucht, Stefan

    Psychopharmakotherapie : Supplement

    2005  Volume 12, Issue -, Page(s) 8

    Language German
    Document type Article
    ZDB-ID 1451951-3
    ISSN 0946-5146
    Database Current Contents Medicine

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  2. Article ; Online: Taking uncertainty in the assessment of response into account: An advanced guideline for computing responder rates in clinical trials.

    Zitzmann, Steffen / Lindner, Christoph / Leucht, Claudia / Leucht, Stefan

    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology

    2024  Volume 85, Page(s) 3–4

    Language English
    Publishing date 2024-04-20
    Publishing country Netherlands
    Document type Letter
    ZDB-ID 1082947-7
    ISSN 1873-7862 ; 0924-977X
    ISSN (online) 1873-7862
    ISSN 0924-977X
    DOI 10.1016/j.euroneuro.2024.03.008
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Let us not rush back to odds ratios without a recommendation to convert them to interpretable measures.

    Leucht, Stefan

    Journal of clinical epidemiology

    2021  Volume 134, Page(s) 172–173

    MeSH term(s) Humans ; Odds Ratio
    Language English
    Publishing date 2021-02-25
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 639306-8
    ISSN 1878-5921 ; 0895-4356
    ISSN (online) 1878-5921
    ISSN 0895-4356
    DOI 10.1016/j.jclinepi.2021.02.017
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Book ; Conference proceedings: Treatment optimisation in schizophrenia through active patient management

    Leucht, Stefan

    proceedings from two European consensus meetings [during 2006, Milan on 8 and 9 June ... Bordeaux on 14 June]

    (Acta psychiatrica Scandinavica : Supplementum ; 438)

    2009  

    Author's details guest ed.: Stefan Leucht
    Series title Acta psychiatrica Scandinavica : Supplementum ; 438
    Acta psychiatrica Scandinavica
    Acta psychiatrica Scandinavica ; Supplementum
    Collection Acta psychiatrica Scandinavica
    Acta psychiatrica Scandinavica ; Supplementum
    Language English
    Size 40 S.
    Publisher Blackwell
    Publishing place Oxford
    Publishing country Great Britain
    Document type Book ; Conference proceedings
    HBZ-ID HT015820232
    Database Catalogue ZB MED Medicine, Health

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  5. Article ; Online: A potential issue with PANSS responder analysis.

    Zitzmann, Steffen / Lindner, Christoph / Leucht, Claudia / Leucht, Stefan

    Schizophrenia research

    2023  Volume 261, Page(s) 287–290

    Language English
    Publishing date 2023-10-23
    Publishing country Netherlands
    Document type Letter
    ZDB-ID 639422-x
    ISSN 1573-2509 ; 0920-9964
    ISSN (online) 1573-2509
    ISSN 0920-9964
    DOI 10.1016/j.schres.2023.10.009
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Book: Physical illness and schizophrenia

    Leucht, Stefan

    a review of the evidence

    2007  

    Author's details Stefan Leucht
    Keywords Schizophrenia/Complications ; Schizophrenics/Health and hygiene
    Subject code 616.898
    Language English
    Size XV, 208 S. : graph. Darst., 23cm
    Publisher Cambridge Univ. Press
    Publishing place Cambridge
    Publishing country Great Britain
    Document type Book
    HBZ-ID HT015323165
    ISBN 978-0-521-88264-4 ; 0-521-88264-8
    Database Catalogue ZB MED Medicine, Health

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  7. Book: Therapie der Schizophrenie

    Leucht, Stefan

    evidenzbasierte Behandlung

    2007  

    Author's details Stefan Leucht
    Keywords Schizophrenie ; Neuroleptikum ; Evidenz-basierte Medizin
    Subject Evidence-based medicine ; Gutachtenbasierte Medizin ; Evidenzbasierte Medizin ; Depotneuroleptikum ; Langzeitneuroleptikum ; Neuroplegikum ; Psycholeptikum ; Antipsychotikum ; Neuroleptika ; Spaltungsirresein ; Schizophrene Psychose
    Language German
    Size XI, 228 S. : graph. Darst.
    Edition 1. Aufl.
    Publisher Elsevier, Urban & Fischer
    Publishing place München u.a.
    Publishing country Germany
    Document type Book
    HBZ-ID HT015220942
    ISBN 978-3-437-24350-9 ; 3-437-24350-0
    Database Catalogue ZB MED Medicine, Health

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  8. Book ; Conference proceedings: From bench to bedside: update on schizophrenia

    Leucht, Stefan

    proceedings from Mind Matters, 6th International Psychiatry Forum, Athens, Greece, June 10 - 12, 2005

    (International clinical psychopharmacology ; 21, Suppl. 2)

    2006  

    Event/congress Mind Matters Conference (2005, Athen) ; International Psychiatry Forum (6, 2005, Athen)
    Author's details guest ed.: Stefan Leucht
    Series title International clinical psychopharmacology ; 21, Suppl. 2
    Collection
    Language English
    Size S19 S. : graph. Darst.
    Publisher Lippincott Williams & Wilkins
    Publishing place Hagerstown, MD
    Publishing country United States
    Document type Book ; Conference proceedings
    HBZ-ID HT014769218
    Database Catalogue ZB MED Medicine, Health

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  9. Article ; Online: Clinician- versus caregiver-rated scales as outcome measures of repetitive-restricted behaviors in clinical trials of autism: A systematic review and meta-analysis.

    Siafis, Spyridon / Leucht, Stefan

    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology

    2023  Volume 70, Page(s) 56–62

    Abstract: The agreement between treatment effects measured by clinician- and caregiver-ratings of repetitive-restricted behaviors (RRBs) is important for clinical practice and research but is still unclear. Therefore, we conducted a post-hoc meta-analysis of ... ...

    Abstract The agreement between treatment effects measured by clinician- and caregiver-ratings of repetitive-restricted behaviors (RRBs) is important for clinical practice and research but is still unclear. Therefore, we conducted a post-hoc meta-analysis of placebo-controlled randomized-controlled trials (RCTs) investigating pharmacological and dietary-supplement treatments for autism that reported both clinician- and caregiver-ratings of RRBs. Treatment effects between medications and placebo were quantified with standardized mean differences (SMDs). The agreement between clinician- and caregiver-rated SMDs was investigated with an intraclass correlation coefficient (ICC) and random-effects meta-analysis of their difference (Δg). A meta-regression investigated the association between clinician (dependent) and caregiver-rated SMDs (independent variable). Certainty in the evidence was evaluated using the GRADE approach. We identified 15 eligible placebo-controlled RCTs with 1567 participants, from which 13 included children/adolescents and 9 reported data for the pair of the clinician-rated Yale-Brown Obsessive Compulsive Scale (YBOCS) and the caregiver-rated Aberrant Behavior Checklist-Stereotypic Behavior (ABC-S). There was on average a good agreement between clinician- and caregiver-rated SMDs (ICC=0.84, 95% confidence intervals [0.55, 0.95]), no clear difference between them (Δg=0.08, 95%CI[-0.06, 0.21], 95% prediction intervals [-0.16, 0.31]), and the beta of the meta-regression was 0.62, 95%CI[0.27, 0.97]. The certainty of the evidence was low due to concerns in imprecision and inconsistency. Our analysis showed on average a good agreement between clinician- and caregiver-rated treatment effects in RRBs, yet discordance could be expected in future RCTs, given the wide prediction intervals. It is also not certain that these results could be generalizable to other rating scales and intervention modalities. Ethics committee approval: Not applicable as a meta-analysis of previously published studies..
    MeSH term(s) Child ; Adolescent ; Humans ; Autistic Disorder/diagnosis ; Autistic Disorder/drug therapy ; Caregivers ; Outcome Assessment, Health Care
    Language English
    Publishing date 2023-03-02
    Publishing country Netherlands
    Document type Meta-Analysis ; Systematic Review ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1082947-7
    ISSN 1873-7862 ; 0924-977X
    ISSN (online) 1873-7862
    ISSN 0924-977X
    DOI 10.1016/j.euroneuro.2023.02.012
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Which first-generation antipsychotics should be "repurposed" for the treatment of schizophrenia.

    Leucht, Stefan / Davis, John M

    European archives of psychiatry and clinical neuroscience

    2022  Volume 272, Issue 1, Page(s) 1–3

    MeSH term(s) Antipsychotic Agents/therapeutic use ; Drug Repositioning ; Humans ; Schizophrenia/drug therapy
    Chemical Substances Antipsychotic Agents
    Language English
    Publishing date 2022-01-17
    Publishing country Germany
    Document type Editorial
    ZDB-ID 1045583-8
    ISSN 1433-8491 ; 0175-758X ; 0940-1334
    ISSN (online) 1433-8491
    ISSN 0175-758X ; 0940-1334
    DOI 10.1007/s00406-021-01378-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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