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  1. Article ; Online: Long-Term Outcome of Same-Day Split Corneal Transplantation in Hong Kong.

    Yeung, Tiffany L M / Ho, Vivian / Li, Brian C Y / Tang, Wilson W T / Li, Kenneth K W

    Cornea

    2021  Volume 40, Issue 9, Page(s) e16

    MeSH term(s) Corneal Transplantation ; Hong Kong ; Humans
    Language English
    Publishing date 2021-05-26
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 604826-2
    ISSN 1536-4798 ; 0277-3740
    ISSN (online) 1536-4798
    ISSN 0277-3740
    DOI 10.1097/ICO.0000000000002765
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Re: Ocular injuries resulting from commercial cosmetic procedures.

    Yeung, Tiffany L M / Ho, Vivian / Li, Brian C Y / Li, Kenneth K W

    Clinical & experimental optometry

    2021  Volume 104, Issue 5, Page(s) 658

    MeSH term(s) Eye Injuries/etiology ; Humans
    Language English
    Publishing date 2021-05-24
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 639275-1
    ISSN 1444-0938 ; 0816-4622
    ISSN (online) 1444-0938
    ISSN 0816-4622
    DOI 10.1080/08164622.2021.1913045
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Amniotic membrane harvesting during COVID-19 pandemic.

    Yeung, Tiffany L M / Liu, Shasha / Li, Brian C Y / Mok, K M / Li, Kenneth K W

    Eye (London, England)

    2020  Volume 35, Issue 3, Page(s) 1019

    MeSH term(s) Amnion ; COVID-19 ; Coronavirus ; Humans ; Ophthalmology ; Pandemics ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-05-12
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 91001-6
    ISSN 1476-5454 ; 0950-222X
    ISSN (online) 1476-5454
    ISSN 0950-222X
    DOI 10.1038/s41433-020-0947-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Amniotic membrane harvesting during COVID-19 pandemic

    Yeung, Tiffany L. M. / Liu, Shasha / Li, Brian C. Y. / Mok, K. M. / Li, Kenneth K. W.

    Eye ; ISSN 0950-222X 1476-5454

    2020  

    Keywords Ophthalmology ; General Arts and Humanities ; covid19
    Language English
    Publisher Springer Science and Business Media LLC
    Publishing country us
    Document type Article ; Online
    DOI 10.1038/s41433-020-0947-4
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article ; Online: Presumed topiramate retinopathy: a case report.

    Yeung, Tiffany L M / Li, Patrick S H / Li, Kenneth K W

    Journal of medical case reports

    2016  Volume 10, Page(s) 210

    Abstract: Background: We report a case of peripheral pigmentary retinopathy and visual field loss following topiramate use for uncontrolled seizures. Such side effects have not been well documented despite the increasing use of topiramate in the past 10 years. A ... ...

    Abstract Background: We report a case of peripheral pigmentary retinopathy and visual field loss following topiramate use for uncontrolled seizures. Such side effects have not been well documented despite the increasing use of topiramate in the past 10 years. A thorough search of available English literature revealed only a small number of reports of topiramate-induced retinopathy or visual field defects in humans. One similar case has been described. We are concerned about the possible rare instances of this occurrence in future patients and hence would like to propose a presumed correlation.
    Case presentation: A 48-year-old Chinese woman developed blurred vision after 9 months of topiramate use. Her visual acuity dropped from 1.2 to 0.7 in both eyes, with bilateral diffuse pigmentary retinopathy and a constricted visual field. Despite an improvement in visual acuity after cessation of the drug, the other clinical findings remained. The temporal relationship between the initiation of topiramate and the visual disturbance suggests that topiramate could be the cause of such signs and symptoms.
    Conclusion: Topiramate potentially causes pigmentary retinopathy and constricted visual field.
    MeSH term(s) Anticonvulsants/adverse effects ; Female ; Fructose/adverse effects ; Fructose/analogs & derivatives ; Humans ; Middle Aged ; Retinitis Pigmentosa/chemically induced ; Vision Disorders/chemically induced
    Chemical Substances Anticonvulsants ; topiramate (0H73WJJ391) ; Fructose (30237-26-4)
    Language English
    Publishing date 2016-08-01
    Publishing country England
    Document type Case Reports ; Journal Article
    ZDB-ID 2269805-X
    ISSN 1752-1947 ; 1752-1947
    ISSN (online) 1752-1947
    ISSN 1752-1947
    DOI 10.1186/s13256-016-0980-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Plasma Lipidomic Profiling Identifies Elevated Triglycerides as Potential Risk Factor in Chemotherapy-Induced Peripheral Neuropathy.

    Yeung, Nicole / Li, Tiffany / Lin, Hui-Ming / Timmins, Hannah C / Goldstein, David / Harrison, Michelle / Friedlander, Michael / Mahon, Kate L / Giles, Corey / Meikle, Peter J / Park, Susanna B / Horvath, Lisa G

    JCO precision oncology

    2024  Volume 8, Page(s) e2300690

    Abstract: Purpose: Chemotherapy-induced peripheral neuropathy (CIPN) is a dose-limiting side effect of cytotoxic cancer treatment, often necessitating dose reduction (DR) or chemotherapy discontinuation (CD). Studies on peripheral neuropathy related to ... ...

    Abstract Purpose: Chemotherapy-induced peripheral neuropathy (CIPN) is a dose-limiting side effect of cytotoxic cancer treatment, often necessitating dose reduction (DR) or chemotherapy discontinuation (CD). Studies on peripheral neuropathy related to chemotherapy, obesity, and diabetes have implicated lipid metabolism. This study examined the association between circulating lipids and CIPN.
    Methods: Lipidomic analysis was performed on plasma samples from 137 patients receiving taxane-based treatment. CIPN was graded using Total Neuropathy Score-clinical version (TNSc) and patient-reported outcome measure European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-CIPN (EORTC-QLQ-CIPN20).
    Results: A significant proportion of elevated baseline lipids were associated with high-grade CIPN defined by TNSc and EORTC-QLQ-CIPN20 including triacylglycerols (TGs). Multivariable Cox regression on lipid species, adjusting for BMI, age, and diabetes, showed several elevated baseline TG associated with shorter time to DR/CD. Latent class analysis identified two baseline lipid profiles with differences in risk of CIPN (hazard ratio, 2.80 [95% CI, 1.50 to 5.23];
    Conclusion: Elevated baseline plasma TG is associated with an increased risk of CIPN development and warrants further validation in other cohorts. Ultimately, this may enable therapeutic intervention.
    MeSH term(s) Humans ; Peripheral Nervous System Diseases/chemically induced ; Peripheral Nervous System Diseases/blood ; Female ; Male ; Lipidomics ; Middle Aged ; Triglycerides/blood ; Risk Factors ; Aged ; Antineoplastic Agents/adverse effects ; Antineoplastic Agents/therapeutic use ; Adult ; Taxoids/adverse effects ; Taxoids/therapeutic use ; Bridged-Ring Compounds
    Chemical Substances Triglycerides ; Antineoplastic Agents ; Taxoids ; taxane (1605-68-1) ; Bridged-Ring Compounds
    Language English
    Publishing date 2024-05-01
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ISSN 2473-4284
    ISSN (online) 2473-4284
    DOI 10.1200/PO.23.00690
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Extended theory of planned behaviour for promoting construction waste recycling in Hong Kong.

    Mak, Tiffany M W / Yu, Iris K M / Wang, Lei / Hsu, Shu-Chien / Tsang, Daniel C W / Li, C N / Yeung, Tiffany L Y / Zhang, Rong / Poon, Chi Sun

    Waste management (New York, N.Y.)

    2018  Volume 83, Page(s) 161–170

    Abstract: Changing individual's recycling attitude and behaviour is of utmost importance in achieving sustainable construction and demolition (C&D) waste management, yet it has often been underachieved. To understand the motivations for recycling, this study ... ...

    Abstract Changing individual's recycling attitude and behaviour is of utmost importance in achieving sustainable construction and demolition (C&D) waste management, yet it has often been underachieved. To understand the motivations for recycling, this study identifies and prioritizes the key factors that affect C&D waste recycling behaviour of various stakeholders in Hong Kong (i.e., representatives from construction-waste-related organizations, environmental consultants and contractors, and government engineers) in a quantitative manner using statistical tools. Different from traditional C&D waste behavioural determinants studies, this paper utilizes an integrated analytical method through semi-structured interviews and survey questionnaire on the basis of Theory of Planned Behaviour (TPB). Qualitative thematic analysis and quantitative frequency analysis were performed to analyse responses from semi-structured interviews and questionnaires, followed by correlation analysis to quantify the relationships between factors. Results indicated that four key factors: (i) regulatory compliance, (ii) economic incentives, (iii) accreditation scheme, and (iv) logistics and management incentives directly influenced recycling behaviour of individuals. Regulatory compliance was the most determining factor for consultants, contractors, experts, and government officials, whereas economic incentives were of great concern to the public. Under the factor of economic incentives, strong positive relationships were identified between disposal costs and collection and sorting costs, thus increasing waste disposal charging fee may promote recycling behaviour. In comparison, accreditation scheme deserved better recognition to facilitate a closed-loop material flow in the construction industry. These findings help to devise more effective and stakeholder-oriented policy tools to raise awareness and encourage behavioural change towards C&D waste recycling, and assist policy makers to establish regulations and practices for sustainable resource management.
    MeSH term(s) Construction Industry ; Construction Materials ; Hong Kong ; Humans ; Recycling ; Waste Management
    Language English
    Publishing date 2018-11-15
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2001471-5
    ISSN 1879-2456 ; 0956-053X
    ISSN (online) 1879-2456
    ISSN 0956-053X
    DOI 10.1016/j.wasman.2018.11.016
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Extended theory of planned behaviour for promoting construction waste recycling in Hong Kong

    Mak, Tiffany M.W / C.N. Li / Chi Sun Poon / Daniel C.W. Tsang / Iris K.M. Yu / Lei Wang / Rong Zhang / Shu-Chien Hsu / Tiffany L.Y. Yeung

    Waste management. 2019 Jan., v. 83

    2019  

    Abstract: Changing individual’s recycling attitude and behaviour is of utmost importance in achieving sustainable construction and demolition (C&D) waste management, yet it has often been underachieved. To understand the motivations for recycling, this study ... ...

    Abstract Changing individual’s recycling attitude and behaviour is of utmost importance in achieving sustainable construction and demolition (C&D) waste management, yet it has often been underachieved. To understand the motivations for recycling, this study identifies and prioritizes the key factors that affect C&D waste recycling behaviour of various stakeholders in Hong Kong (i.e., representatives from construction-waste-related organizations, environmental consultants and contractors, and government engineers) in a quantitative manner using statistical tools. Different from traditional C&D waste behavioural determinants studies, this paper utilizes an integrated analytical method through semi-structured interviews and survey questionnaire on the basis of Theory of Planned Behaviour (TPB). Qualitative thematic analysis and quantitative frequency analysis were performed to analyse responses from semi-structured interviews and questionnaires, followed by correlation analysis to quantify the relationships between factors. Results indicated that four key factors: (i) regulatory compliance, (ii) economic incentives, (iii) accreditation scheme, and (iv) logistics and management incentives directly influenced recycling behaviour of individuals. Regulatory compliance was the most determining factor for consultants, contractors, experts, and government officials, whereas economic incentives were of great concern to the public. Under the factor of economic incentives, strong positive relationships were identified between disposal costs and collection and sorting costs, thus increasing waste disposal charging fee may promote recycling behaviour. In comparison, accreditation scheme deserved better recognition to facilitate a closed-loop material flow in the construction industry. These findings help to devise more effective and stakeholder-oriented policy tools to raise awareness and encourage behavioural change towards C&D waste recycling, and assist policy makers to establish regulations and practices for sustainable resource management.
    Keywords analytical methods ; behavior change ; compliance ; construction industry ; consultants ; contractors ; economic incentives ; engineers ; experts ; interviews ; issues and policy ; motivation ; questionnaires ; recycling ; resource management ; stakeholders ; surveys ; waste disposal ; wastes ; China
    Language English
    Dates of publication 2019-01
    Size p. 161-170.
    Publishing place Elsevier Ltd
    Document type Article
    ZDB-ID 2001471-5
    ISSN 1879-2456 ; 0956-053X
    ISSN (online) 1879-2456
    ISSN 0956-053X
    DOI 10.1016/j.wasman.2018.11.016
    Database NAL-Catalogue (AGRICOLA)

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  9. Article ; Online: Clinical Utility of Real-Time Targeted Molecular Profiling in the Clinical Management of Ovarian Cancer: The ALLOCATE Study.

    Kondrashova, Olga / Ho, Gwo-Yaw / Au-Yeung, George / Leas, Leakhena / Boughtwood, Tiffany / Alsop, Kathryn / Zapparoli, Giada / Dobrovic, Alexander / Ko, Yi-An / Hsu, Arthur L / Love, Clare J / Lunke, Sebastian / Wakefield, Matthew J / McNally, Orla / Quinn, Michael / Ananda, Sumitra / Neesham, Deborah / Hamilton, Anne / Grossi, Marisa /
    Freimund, Alison / Kanjanapan, Yada / Rischin, Danny / Traficante, Nadia / Bowtell, David / Scott, Clare L / Christie, Michael / Taylor, Graham R / Mileshkin, Linda / Waring, Paul M

    JCO precision oncology

    2022  Volume 3, Page(s) 1–18

    Abstract: Purpose: The ALLOCATE study was designed as a pilot to demonstrate the feasibility and clinical utility of real-time targeted molecular profiling of patients with recurrent or advanced ovarian cancer for identification of potential targeted therapies.!## ...

    Abstract Purpose: The ALLOCATE study was designed as a pilot to demonstrate the feasibility and clinical utility of real-time targeted molecular profiling of patients with recurrent or advanced ovarian cancer for identification of potential targeted therapies.
    Patients and methods: A total of 113 patients with ovarian cancer of varying histologies were recruited from two tertiary hospitals, with 99 patient cases suitable for prospective analysis. Targeted molecular and methylation profiling of fresh biopsy and archived tumor samples were performed by screening for mutations or copy-number variations in 44 genes and for promoter methylation of
    Results: Somatic genomic or methylation events were identified in 85% of all patient cases, with potentially actionable events with defined targeted therapies (including four resistance events) detected in 60% of all patient cases. On the basis of these findings, six patients received molecularly guided therapy, three patients had unsuspected germline cancer-associated
    Conclusion: ALLOCATE molecular profiling identified known genomic and methylation alterations of the different ovarian cancer subtypes and was deemed feasible and useful in routine clinical practice. Better patient selection and access to a wider range of targeted therapies or clinical trials will further enhance the clinical utility of molecular profiling.
    Language English
    Publishing date 2022-01-31
    Publishing country United States
    Document type Journal Article
    ISSN 2473-4284
    ISSN (online) 2473-4284
    DOI 10.1200/PO.19.00019
    Database MEDical Literature Analysis and Retrieval System OnLINE

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