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  1. Article ; Online: Evidence for Collective Multiparticle Correlations in p-Pb Collisions.

    Khachatryan, V / Sirunyan, A M / Tumasyan, A / Adam, W / Bergauer, T / Dragicevic, M / Erö, J / Friedl, M / Frühwirth, R / Ghete, V M / Hartl, C / Hörmann, N / Hrubec, J / Jeitler, M / Kiesenhofer, W / Knünz, V / Krammer, M / Krätschmer, I / Liko, D /
    Mikulec, I / Rabady, D / Rahbaran, B / Rohringer, H / Schöfbeck, R / Strauss, J / Treberer-Treberspurg, W / Waltenberger, W / Wulz, C-E / Mossolov, V / Shumeiko, N / Suarez Gonzalez, J / Alderweireldt, S / Bansal, S / Cornelis, T / De Wolf, E A / Janssen, X / Knutsson, A / Lauwers, J / Luyckx, S / Ochesanu, S / Rougny, R / Van De Klundert, M / Van Haevermaet, H / Van Mechelen, P / Van Remortel, N / Van Spilbeeck, A / Blekman, F / Blyweert, S / D'Hondt, J / Daci, N / Heracleous, N / Keaveney, J / Lowette, S / Maes, M / Olbrechts, A / Python, Q / Strom, D / Tavernier, S / Van Doninck, W / Van Mulders, P / Van Onsem, G P / Villella, I / Caillol, C / Clerbaux, B / De Lentdecker, G / Dobur, D / Favart, L / Gay, A P R / Grebenyuk, A / Léonard, A / Mohammadi, A / Perniè, L / Randle-conde, A / Reis, T / Seva, T / Thomas, L / Vander Velde, C / Vanlaer, P / Wang, J / Zenoni, F / Adler, V / Beernaert, K / Benucci, L / Cimmino, A / Costantini, S / Crucy, S / Fagot, A / Garcia, G / Mccartin, J / Ocampo Rios, A A / Poyraz, D / Ryckbosch, D / Salva Diblen, S / Sigamani, M / Strobbe, N / Thyssen, F / Tytgat, M / Yazgan, E / Zaganidis, N / Basegmez, S / Beluffi, C / Bruno, G / Castello, R / Caudron, A / Ceard, L / Da Silveira, G G / Delaere, C / du Pree, T / Favart, D / Forthomme, L / Giammanco, A / Hollar, J / Jafari, A / Jez, P / Komm, M / Lemaitre, V / Nuttens, C / Pagano, D / Perrini, L / Pin, A / Piotrzkowski, K / Popov, A / Quertenmont, L / Selvaggi, M / Vidal Marono, M / Vizan Garcia, J M / Beliy, N / Caebergs, T / Daubie, E / Hammad, G H / Aldá Júnior, W L / Alves, G A / Brito, L / Correa Martins Junior, M / Dos Reis Martins, T / Molina, J / Mora Herrera, C / Pol, M E / Rebello Teles, P / Carvalho, W / Chinellato, J / Custódio, A / Da Costa, E M / De Jesus Damiao, D / De Oliveira Martins, C / Fonseca De Souza, S / Malbouisson, H / Matos Figueiredo, D / Mundim, L / Nogima, H / Prado Da Silva, W L / Santaolalla, J / Santoro, A / Sznajder, A / Tonelli Manganote, E J / Vilela Pereira, A / Bernardes, C A / Dogra, S / Fernandez Perez Tomei, T R / Gregores, E M / Mercadante, P G / Novaes, S F / Padula, Sandra S / Aleksandrov, A / Genchev, V / Hadjiiska, R / Iaydjiev, P / Marinov, A / Piperov, S / Rodozov, M / Stoykova, S / Sultanov, G / Vutova, M / Dimitrov, A / Glushkov, I / Litov, L / Pavlov, B / Petkov, P / Bian, J G / Chen, G M / Chen, H S / Chen, M / Cheng, T / Du, R / Jiang, C H / Plestina, R / Romeo, F / Tao, J / Wang, Z / Asawatangtrakuldee, C / Ban, Y / Liu, S / Mao, Y / Qian, S J / Wang, D / Xu, Z / Zhang, F / Zhang, L / Zou, W / Avila, C / Cabrera, A / Chaparro Sierra, L F / Florez, C / Gomez, J P / Gomez Moreno, B / Sanabria, J C / Godinovic, N / Lelas, D / Polic, D / Puljak, I / Antunovic, Z / Kovac, M / Brigljevic, V / Kadija, K / Luetic, J / Mekterovic, D / Sudic, L / Attikis, A / Mavromanolakis, G / Mousa, J / Nicolaou, C / Ptochos, F / Razis, P A / Rykaczewski, H / Bodlak, M / Finger, M / Assran, Y / Ellithi Kamel, A / Mahmoud, M A / Radi, A / Kadastik, M / Murumaa, M / Raidal, M / Tiko, A / Eerola, P / Voutilainen, M / Härkönen, J / Karimäki, V / Kinnunen, R / Kortelainen, M J / Lampén, T / Lassila-Perini, K / Lehti, S / Lindén, T / Luukka, P / Mäenpää, T / Peltola, T / Tuominen, E / Tuominiemi, J / Tuovinen, E / Wendland, L / Talvitie, J / Tuuva, T / Besancon, M / Couderc, F / Dejardin, M / Denegri, D / Fabbro, B / Faure, J L / Favaro, C / Ferri, F / Ganjour, S / Givernaud, A / Gras, P / Hamel de Monchenault, G / Jarry, P / Locci, E / Malcles, J / Rander, J / Rosowsky, A / Titov, M / Baffioni, S / Beaudette, F / Busson, P / Chapon, E / Charlot, C / Dahms, T / Dobrzynski, L / Filipovic, N / Florent, A / Granier de Cassagnac, R / Mastrolorenzo, L / Miné, P / Naranjo, I N / Nguyen, M / Ochando, C / Ortona, G / Paganini, P / Regnard, S / Salerno, R / Sauvan, J B / Sirois, Y / Veelken, C / Yilmaz, Y / Zabi, A / Agram, J-L / Andrea, J / Aubin, A / Bloch, D / Brom, J-M / Chabert, E C / Collard, C / Conte, E / Fontaine, J-C / Gelé, D / Goerlach, U / Goetzmann, C / Le Bihan, A-C / Skovpen, K / Van Hove, P / Gadrat, S / Beauceron, S / Beaupere, N / Bernet, C / Boudoul, G / Bouvier, E / Brochet, S / Carrillo Montoya, C A / Chasserat, J / Chierici, R / Contardo, D / Courbon, B / Depasse, P / El Mamouni, H / Fan, J / Fay, J / Gascon, S / Gouzevitch, M / Ille, B / Kurca, T / Lethuillier, M / Mirabito, L / Pequegnot, A L / Perries, S / Ruiz Alvarez, J D / Sabes, D / Sgandurra, L / Sordini, V / Vander Donckt, M / Verdier, P / Viret, S / Xiao, H / Tsamalaidze, Z / Autermann, C / Beranek, S / Bontenackels, M / Edelhoff, M / Feld, L / Heister, A / Klein, K / Lipinski, M / Ostapchuk, A / Preuten, M / Raupach, F / Sammet, J / Schael, S / Schulte, J F / Weber, H / Wittmer, B / Zhukov, V / Ata, M / Brodski, M / Dietz-Laursonn, E / Duchardt, D / Erdmann, M / Fischer, R / Güth, A / Hebbeker, T / Heidemann, C / Hoepfner, K / Klingebiel, D / Knutzen, S / Kreuzer, P / Merschmeyer, M / Meyer, A / Millet, P / Olschewski, M / Padeken, K / Papacz, P / Reithler, H / Schmitz, S A / Sonnenschein, L / Teyssier, D / Thüer, S / Cherepanov, V / Erdogan, Y / Flügge, G / Geenen, H / Geisler, M / Haj Ahmad, W / Hoehle, F / Kargoll, B / Kress, T / Kuessel, Y / Künsken, A / Lingemann, J / Nowack, A / Nugent, I M / Pistone, C / Pooth, O / Stahl, A / Aldaya Martin, M / Asin, I / Bartosik, N / Behr, J / Behrens, U / Bell, A J / Bethani, A / Borras, K / Burgmeier, A / Cakir, A / Calligaris, L / Campbell, A / Choudhury, S / Costanza, F / Diez Pardos, C / Dolinska, G / Dooling, S / Dorland, T / Eckerlin, G / Eckstein, D / Eichhorn, T / Flucke, G / Garay Garcia, J / Geiser, A / Gizhko, A / Gunnellini, P / Hauk, J / Hempel, M / Jung, H / Kalogeropoulos, A / Karacheban, O / Kasemann, M / Katsas, P / Kieseler, J / Kleinwort, C / Korol, I / Krücker, D / Lange, W / Leonard, J / Lipka, K / Lobanov, A / Lohmann, W / Lutz, B / Mankel, R / Marfin, I / Melzer-Pellmann, I-A / Meyer, A B / Mittag, G / Mnich, J / Mussgiller, A / Naumann-Emme, S / Nayak, A / Ntomari, E / Perrey, H / Pitzl, D / Placakyte, R / Raspereza, A / Ribeiro Cipriano, P M / Roland, B / Ron, E / Sahin, M Ö / Salfeld-Nebgen, J / Saxena, P / Schoerner-Sadenius, T / Schröder, M / Seitz, C / Spannagel, S / Vargas Trevino, A D R / Walsh, R / Wissing, C / Blobel, V / Centis Vignali, M / Draeger, A R / Erfle, J / Garutti, E / Goebel, K / Görner, M / Haller, J / Hoffmann, M / Höing, R S / Junkes, A / Kirschenmann, H / Klanner, R / Kogler, R / Lapsien, T / Lenz, T / Marchesini, I / Marconi, D / Ott, J / Peiffer, T / Perieanu, A / Pietsch, N / Poehlsen, J / Poehlsen, T / Rathjens, D / Sander, C / Schettler, H / Schleper, P / Schlieckau, E / Schmidt, A / Seidel, M / Sola, V / Stadie, H / Steinbrück, G / Troendle, D / Usai, E / Vanelderen, L / Vanhoefer, A / Barth, C / Baus, C / Berger, J / Böser, C / Butz, E / Chwalek, T / De Boer, W / Descroix, A / Dierlamm, A / Feindt, M / Frensch, F / Giffels, M / Gilbert, A / Hartmann, F / Hauth, T / Husemann, U / Katkov, I / Kornmayer, A / Lobelle Pardo, P / Mozer, M U / Müller, T / Müller, Th / Nürnberg, A / Quast, G / Rabbertz, K / Röcker, S / Simonis, H J / Stober, F M / Ulrich, R / Wagner-Kuhr, J / Wayand, S / Weiler, T / Wolf, R / Anagnostou, G / Daskalakis, G / Geralis, T / Giakoumopoulou, V A / Kyriakis, A / Loukas, D / Markou, A / Markou, C / Psallidas, A / Topsis-Giotis, I / Agapitos, A / Kesisoglou, S / Panagiotou, A / Saoulidou, N / Stiliaris, E / Tziaferi, E / Aslanoglou, X / Evangelou, I / Flouris, G / Foudas, C / Kokkas, P / Manthos, N / Papadopoulos, I / Paradas, E / Strologas, J / Bencze, G / Hajdu, C / Hidas, P / Horvath, D / Sikler, F / Veszpremi, V / Vesztergombi, G / Zsigmond, A J / Beni, N / Czellar, S / Karancsi, J / Molnar, J / Palinkas, J / Szillasi, Z / Makovec, A / Raics, P / Trocsanyi, Z L / Ujvari, B / Swain, S K / Beri, S B / Bhatnagar, V / Gupta, R / Bhawandeep, U / Kalsi, A K / Kaur, M / Kumar, R / Mittal, M / Nishu, N / Singh, J B / Kumar, Ashok / Kumar, Arun / Ahuja, S / Bhardwaj, A / Choudhary, B C / Kumar, A / Malhotra, S / Naimuddin, M / Ranjan, K / Sharma, V / Banerjee, S / Bhattacharya, S / Chatterjee, K / Dutta, S / Gomber, B / Jain, Sa / Jain, Sh / Khurana, R / Modak, A / Mukherjee, S / Roy, D / Sarkar, S / Sharan, M / Abdulsalam, A / Dutta, D / Kumar, V / Mohanty, A K / Pant, L M / Shukla, P / Topkar, A / Aziz, T / Bhowmik, S / Chatterjee, R M / Dewanjee, R K / Dugad, S / Ganguly, S / Ghosh, S / Guchait, M / Gurtu, A / Kole, G / Kumar, S / Maity, M / Majumder, G / Mazumdar, K / Mohanty, G B / Parida, B / Sudhakar, K / Wickramage, N / Sharma, S / Bakhshiansohi, H / Behnamian, H / Etesami, S M / Fahim, A / Goldouzian, R / Khakzad, M / Mohammadi Najafabadi, M / Naseri, M / Paktinat Mehdiabadi, S / Rezaei Hosseinabadi, F / Safarzadeh, B / Zeinali, M / Felcini, M / Grunewald, M / Abbrescia, M / Calabria, C / Chhibra, S S / Colaleo, A / Creanza, D / Cristella, L / De Filippis, N / De Palma, M / Fiore, L / Iaselli, G / Maggi, G / Maggi, M / My, S / Nuzzo, S / Pompili, A / Pugliese, G / Radogna, R / Selvaggi, G / Sharma, A / Silvestris, L / Venditti, R / Verwilligen, P / Abbiendi, G / Benvenuti, A C / Bonacorsi, D / Braibant-Giacomelli, S / Brigliadori, L / Campanini, R / Capiluppi, P / Castro, A / Cavallo, F R / Codispoti, G / Cuffiani, M / Dallavalle, G M / Fabbri, F / Fanfani, A / Fasanella, D / Giacomelli, P / Grandi, C / Guiducci, L / Marcellini, S / Masetti, G / Montanari, A / Navarria, F L / Perrotta, A / Rossi, A M / Rovelli, T / Siroli, G P / Tosi, N / Travaglini, R / Albergo, S / Cappello, G / Chiorboli, M / Costa, S / Giordano, F / Potenza, R / Tricomi, A / Tuve, C / Barbagli, G / Ciulli, V / Civinini, C / D'Alessandro, R / Focardi, E / Gallo, E / Gonzi, S / Gori, V / Lenzi, P / Meschini, M / Paoletti, S / Sguazzoni, G / Tropiano, A / Benussi, L / Bianco, S / Piccolo, D / Ferretti, R / Ferro, F / Lo Vetere, M / Robutti, E / Tosi, S / Dinardo, M E / Fiorendi, S / Gennai, S / Gerosa, R / Ghezzi, A / Govoni, P / Lucchini, M T / Malvezzi, S / Manzoni, R A / Martelli, A / Marzocchi, B / Menasce, D / Moroni, L / Paganoni, M / Pedrini, D / Ragazzi, S / Redaelli, N / Tabarelli de Fatis, T / Buontempo, S / Cavallo, N / Di Guida, S / Fabozzi, F / Iorio, A O M / Lista, L / Meola, S / Merola, M / Paolucci, P / Azzi, P / Bacchetta, N / Bisello, D / Carlin, R / Checchia, P / Dall'Osso, M / Dorigo, T / Dosselli, U / Gasparini, U / Gozzelino, A / Lacaprara, S / Margoni, M / Meneguzzo, A T / Pazzini, J / Pegoraro, M / Pozzobon, N / Ronchese, P / Simonetto, F / Torassa, E / Tosi, M / Vanini, S / Ventura, S / Zotto, P / Zucchetta, A / Zumerle, G / Gabusi, M / Ratti, S P / Re, V / Riccardi, C / Salvini, P / Vitulo, P / Biasini, M / Bilei, G M / Ciangottini, D / Fanò, L / Lariccia, P / Mantovani, G / Menichelli, M / Saha, A / Santocchia, A / Spiezia, A / Androsov, K / Azzurri, P / Bagliesi, G / Bernardini, J / Boccali, T / Broccolo, G / Castaldi, R / Ciocci, M A / Dell'Orso, R / Donato, S / Fedi, G / Fiori, F / Foà, L / Giassi, A / Grippo, M T / Ligabue, F / Lomtadze, T / Martini, L / Messineo, A / Moon, C S / Palla, F / Rizzi, A / Savoy-Navarro, A / Serban, A T / Spagnolo, P / Squillacioti, P / Tenchini, R / Tonelli, G / Venturi, A / Verdini, P G / Vernieri, C / Barone, L / Cavallari, F / D'imperio, G / Del Re, D / Diemoz, M / Jorda, C / Longo, E / Margaroli, F / Meridiani, P / Micheli, F / Organtini, G / Paramatti, R / Rahatlou, S / Rovelli, C / Santanastasio, F / Soffi, L / Traczyk, P / Amapane, N / Arcidiacono, R / Argiro, S / Arneodo, M / Bellan, R / Biino, C / Cartiglia, N / Casasso, S / Costa, M / Covarelli, R / Degano, A / Demaria, N / Finco, L / Mariotti, C / Maselli, S / Migliore, E / Monaco, V / Musich, M / Obertino, M M / Pacher, L / Pastrone, N / Pelliccioni, M / Pinna Angioni, G L / Potenza, A / Romero, A / Ruspa, M / Sacchi, R / Solano, A / Staiano, A / Tamponi, U / Belforte, S / Candelise, V / Casarsa, M / Cossutti, F / Della Ricca, G / Gobbo, B / La Licata, C / Marone, M / Schizzi, A / Umer, T / Zanetti, A / Chang, S / Kropivnitskaya, A / Nam, S K / Kim, D H / Kim, G N / Kim, M S / Kong, D J / Lee, S / Oh, Y D / Park, H / Sakharov, A / Son, D C / Kim, T J / Ryu, M S / Kim, J Y / Moon, D H / Song, S / Choi, S / Gyun, D / Hong, B / Jo, M / Kim, H / Kim, Y / Lee, B / Lee, K S / Park, S K / Roh, Y / Yoo, H D / Choi, M / Kim, J H / Park, I C / Ryu, G / Choi, Y / Choi, Y K / Goh, J / Kim, D / Kwon, E / Lee, J / Yu, I / Juodagalvis, A / Komaragiri, J R / Md Ali, M A B / Wan Abdullah, W A T / Casimiro Linares, E / Castilla-Valdez, H / De La Cruz-Burelo, E / Heredia-de La Cruz, I / Hernandez-Almada, A / Lopez-Fernandez, R / Sanchez-Hernandez, A / Carrillo Moreno, S / Vazquez Valencia, F / Pedraza, I / Salazar Ibarguen, H A / Morelos Pineda, A / Krofcheck, D / Butler, P H / Reucroft, S / Ahmad, A / Ahmad, M / Hassan, Q / Hoorani, H R / Khan, W A / Khurshid, T / Shoaib, M / Bialkowska, H / Bluj, M / Boimska, B / Frueboes, T / Górski, M / Kazana, M / Nawrocki, K / Romanowska-Rybinska, K / Szleper, M / Zalewski, P / Brona, G / Bunkowski, K / Cwiok, M / Dominik, W / Doroba, K / Kalinowski, A / Konecki, M / Krolikowski, J / Misiura, M / Olszewski, M / Bargassa, P / Beirão Da Cruz E Silva, C / Faccioli, P / Ferreira Parracho, P G / Gallinaro, M / Lloret Iglesias, L / Nguyen, F / Rodrigues Antunes, J / Seixas, J / Vadruccio, D / Varela, J / Vischia, P / Afanasiev, S / Bunin, P / Gavrilenko, M / Golutvin, I / Gorbunov, I / Kamenev, A / Karjavin, V / Konoplyanikov, V / Lanev, A / Malakhov, A / Matveev, V / Moisenz, P / Palichik, V / Perelygin, V / Shmatov, S / Skatchkov, N / Smirnov, V / Zarubin, A / Golovtsov, V / Ivanov, Y / Kim, V / Kuznetsova, E / Levchenko, P / Murzin, V / Oreshkin, V / Smirnov, I / Sulimov, V / Uvarov, L / Vavilov, S / Vorobyev, A / Vorobyev, An / Andreev, Yu / Dermenev, A / Gninenko, S / Golubev, N / Kirsanov, M / Krasnikov, N / Pashenkov, A / Tlisov, D / Toropin, A / Epshteyn, V / Gavrilov, V / Lychkovskaya, N / Popov, V / Pozdnyakov, I / Safronov, G / Semenov, S / Spiridonov, A / Stolin, V / Vlasov, E / Zhokin, A / Andreev, V / Azarkin, M / Dremin, I / Kirakosyan, M / Leonidov, A / Mesyats, G / Rusakov, S V / Vinogradov, A / Belyaev, A / Boos, E / Ershov, A / Gribushin, A / Kaminskiy, A / Kodolova, O / Korotkikh, V / Lokhtin, I / Obraztsov, S / Petrushanko, S / Savrin, V / Snigirev, A / Vardanyan, I / Azhgirey, I / Bayshev, I / Bitioukov, S / Kachanov, V / Kalinin, A / Konstantinov, D / Krychkine, V / Petrov, V / Ryutin, R / Sobol, A / Tourtchanovitch, L / Troshin, S / Tyurin, N / Uzunian, A / Volkov, A / Adzic, P / Ekmedzic, M / Milosevic, J / Rekovic, V / Alcaraz Maestre, J / Battilana, C / Calvo, E / Cerrada, M / Chamizo Llatas, M / Colino, N / De La Cruz, B / Delgado Peris, A / Domínguez Vázquez, D / Escalante Del Valle, A / Fernandez Bedoya, C / Fernández Ramos, J P / Flix, J / Fouz, M C / Garcia-Abia, P / Gonzalez Lopez, O / Goy Lopez, S / Hernandez, J M / Josa, M I / Navarro De Martino, E / Pérez-Calero Yzquierdo, A / Puerta Pelayo, J / Quintario Olmeda, A / Redondo, I / Romero, L / Soares, M S / Albajar, C / de Trocóniz, J F / Missiroli, M / Moran, D / Brun, H / Cuevas, J / Fernandez Menendez, J / Folgueras, S / Gonzalez Caballero, I / Brochero Cifuentes, J A / Cabrillo, I J / Calderon, A / Duarte Campderros, J / Fernandez, M / Gomez, G / Graziano, A / Lopez Virto, A / Marco, J / Marco, R / Martinez Rivero, C / Matorras, F / Munoz Sanchez, F J / Piedra Gomez, J / Rodrigo, T / Rodríguez-Marrero, A Y / Ruiz-Jimeno, A / Scodellaro, L / Vila, I / Vilar Cortabitarte, R / Abbaneo, D / Auffray, E / Auzinger, G / Bachtis, M / Baillon, P / Ball, A H / Barney, D / Benaglia, A / Bendavid, J / Benhabib, L / Benitez, J F / Bloch, P / Bocci, A / Bonato, A / Bondu, O / Botta, C / Breuker, H / Camporesi, T / Cerminara, G / Colafranceschi, S / D'Alfonso, M / d'Enterria, D / Dabrowski, A / David, A / De Guio, F / De Roeck, A / De Visscher, S / Di Marco, E / Dobson, M / Dordevic, M / Dorney, B / Dupont-Sagorin, N / Elliott-Peisert, A / Franzoni, G / Funk, W / Gigi, D / Gill, K / Giordano, D / Girone, M / Glege, F / Guida, R / Gundacker, S / Guthoff, M / Hammer, J / Hansen, M / Harris, P / Hegeman, J / Innocente, V / Janot, P / Kousouris, K / Krajczar, K / Lecoq, P / Lourenço, C / Magini, N / Malgeri, L / Mannelli, M / Marrouche, J / Masetti, L / Meijers, F / Mersi, S / Meschi, E / Moortgat, F / Morovic, S / Mulders, M / Orfanelli, S / Orsini, L / Pape, L / Perez, E / Petrilli, A / Petrucciani, G / Pfeiffer, A / Pimiä, M / Piparo, D / Plagge, M / Racz, A / Rolandi, G / Rovere, M / Sakulin, H / Schäfer, C / Schwick, C / Siegrist, P / Silva, P / Simon, M / Sphicas, P / Spiga, D / Steggemann, J / Stieger, B / Stoye, M / Takahashi, Y / Treille, D / Tsirou, A / Veres, G I / Wardle, N / Wöhri, H K / Wollny, H / Zeuner, W D / Bertl, W / Deiters, K / Erdmann, W / Horisberger, R / Ingram, Q / Kaestli, H C / Kotlinski, D / Langenegger, U / Renker, D / Rohe, T / Bachmair, F / Bäni, L / Bianchini, L / Buchmann, M A / Casal, B / Chanon, N / Dissertori, G / Dittmar, M / Donegà, M / Dünser, M / Eller, P / Grab, C / Hits, D / Hoss, J / Kasieczka, G / Lustermann, W / Mangano, B / Marini, A C / Marionneau, M / Martinez Ruiz del Arbol, P / Masciovecchio, M / Meister, D / Mohr, N / Musella, P / Nägeli, C / Nessi-Tedaldi, F / Pandolfi, F / Pauss, F / Perrozzi, L / Peruzzi, M / Quittnat, M / Rebane, L / Rossini, M / Starodumov, A / Takahashi, M / Theofilatos, K / Wallny, R / Weber, H A / Amsler, C / Canelli, M F / Chiochia, V / De Cosa, A / Hinzmann, A / Hreus, T / Kilminster, B / Lange, C / Ngadiuba, J / Pinna, D / Robmann, P / Ronga, F J / Taroni, S / Yang, Y / Cardaci, M / Chen, K H / Ferro, C / Kuo, C M / Lin, W / Lu, Y J / Volpe, R / Yu, S S / Chang, P / Chang, Y H / Chao, Y / Chen, K F / Chen, P H / Dietz, C / Grundler, U / Hou, W-S / Liu, Y F / Lu, R-S / Miñano Moya, M / Petrakou, E / Tsai, J F / Tzeng, Y M / Wilken, R / Asavapibhop, B / Singh, G / Srimanobhas, 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Womersley, W J / Worm, S D / Baber, M / Bainbridge, R / Buchmuller, O / Burton, D / Colling, D / Cripps, N / Dauncey, P / Davies, G / Della Negra, M / Dunne, P / Elwood, A / Ferguson, W / Fulcher, J / Futyan, D / Hall, G / Iles, G / Jarvis, M / Karapostoli, G / Kenzie, M / Lane, R / Lucas, R / Lyons, L / Magnan, A-M / Malik, S / Mathias, B / Nash, J / Nikitenko, A / Pela, J / Pesaresi, M / Petridis, K / Raymond, D M / Rogerson, S / Rose, A / Seez, C / Sharp, P / Tapper, A / Vazquez Acosta, M / Virdee, T / Zenz, S C / Cole, J E / Hobson, P R / Khan, A / Kyberd, P / Leggat, D / Leslie, D / Reid, I D / Symonds, P / Teodorescu, L / Turner, M / Dittmann, J / Hatakeyama, K / Kasmi, A / Liu, H / Pastika, N / Scarborough, T / Wu, Z / Charaf, O / Cooper, S I / Henderson, C / Rumerio, P / Avetisyan, A / Bose, T / Fantasia, C / Lawson, P / Richardson, C / Rohlf, J / St John, J / Sulak, L / Alimena, J / Berry, E / Christopher, G / Cutts, D / Demiragli, Z / Dhingra, N / Ferapontov, A / Garabedian, 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Libeiro, T / Volobouev, I / Appelt, E / Delannoy, A G / Greene, S / Gurrola, A / Johns, W / Maguire, C / Melo, A / Sharma, M / Sheldon, P / Snook, B / Tuo, S / Velkovska, J / Arenton, M W / Boutle, S / Cox, B / Francis, B / Goodell, J / Hirosky, R / Ledovskoy, A / Li, H / Lin, C / Neu, C / Wolfe, E / Wood, J / Clarke, C / Harr, R / Karchin, P E / Kottachchi Kankanamge Don, C / Lamichhane, P / Sturdy, J / Belknap, D A / Carlsmith, D / Cepeda, M / Dasu, S / Dodd, L / Duric, S / Friis, E / Hall-Wilton, R / Herndon, M / Hervé, A / Klabbers, P / Lanaro, A / Lazaridis, C / Levine, A / Loveless, R / Mohapatra, A / Ojalvo, I / Perry, T / Pierro, G A / Polese, G / Ross, I / Sarangi, T / Savin, A / Smith, W H / Taylor, D / Vuosalo, C / Woods, N

    Physical review letters

    2015  Volume 115, Issue 1, Page(s) 12301

    Abstract: The second-order azimuthal anisotropy Fourier harmonics, v2, are obtained in p-Pb and PbPb ... The p-Pb data, corresponding to an integrated luminosity of 35  nb-1, were collected during the 2013 LHC ... p-Pb run at a nucleon-nucleon center-of-mass energy of 5.02  TeV by the CMS experiment. A sample ...

    Abstract The second-order azimuthal anisotropy Fourier harmonics, v2, are obtained in p-Pb and PbPb collisions over a wide pseudorapidity (η) range based on correlations among six or more charged particles. The p-Pb data, corresponding to an integrated luminosity of 35  nb-1, were collected during the 2013 LHC p-Pb run at a nucleon-nucleon center-of-mass energy of 5.02  TeV by the CMS experiment. A sample of semiperipheral PbPb collision data at √sNN=2.76  TeV, corresponding to an integrated luminosity of 2.5  μb-1 and covering a similar range of particle multiplicities as the p-Pb data, is also analyzed for comparison. The six- and eight-particle cumulant and the Lee-Yang zeros methods are used to extract the v2 coefficients, extending previous studies of two- and four-particle correlations. For both the p-Pb and PbPb systems, the v2 values obtained with correlations among more than four particles are consistent with previously published four-particle results. These data support the interpretation of a collective origin for the previously observed long-range (large Δη) correlations in both systems. The ratios of v2 values corresponding to correlations including different numbers of particles are compared to theoretical predictions that assume a hydrodynamic behavior of a p-Pb system dominated by fluctuations in the positions of participant nucleons. These results provide new insights into the multiparticle dynamics of collision systems with a very small overlapping region.
    Language English
    Publishing date 2015-07-03
    Publishing country United States
    Document type Journal Article
    ZDB-ID 208853-8
    ISSN 1079-7114 ; 0031-9007
    ISSN (online) 1079-7114
    ISSN 0031-9007
    DOI 10.1103/PhysRevLett.115.012301
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Remote Sensing of Complex Permittivity and Penetration Depth of Soils Using P-Band SAR Polarimetry

    Anke Fluhrer / Thomas Jagdhuber / Alireza Tabatabaeenejad / Hamed Alemohammad / Carsten Montzka / Peter Friedl / Ehsan Forootan / Harald Kunstmann

    Remote Sensing, Vol 14, Iss 2755, p

    2022  Volume 2755

    Abstract: A P-band SAR moisture estimation method is introduced for complex soil permittivity and penetration ... depth estimation using fully polarimetric P-band SAR signals. This method combines eigen- and model ... of vegetation types. The technique is demonstrated for airborne P-band SAR measurements acquired during the AirMOSS ...

    Abstract A P-band SAR moisture estimation method is introduced for complex soil permittivity and penetration depth estimation using fully polarimetric P-band SAR signals. This method combines eigen- and model-based decomposition techniques for separation of the total backscattering signal into three scattering components (soil, dihedral, and volume). The incorporation of a soil scattering model allows for the first time the estimation of complex soil permittivity and permittivity-based penetration depth. The proposed method needs no prior assumptions on land cover characteristics and is applicable to a variety of vegetation types. The technique is demonstrated for airborne P-band SAR measurements acquired during the AirMOSS campaign (2012–2015). The estimated complex permittivity agrees well with climate and soil conditions at different monitoring sites. Based on frequency and permittivity, P-band penetration depths vary from 5 cm to 35 cm. This value range is in accordance with previous studies in the literature. Comparison of the results is challenging due to the sparsity of vertical soil in situ sampling. It was found that the disagreement between in situ measurements and SAR-based estimates originates from the discrepancy between the in situ measuring depth of the top-soil layer (0–5 cm) and the median penetration depth of the P-band waves (24.5–27 cm).
    Keywords AirMOSS ; polarimetric decomposition ; soil moisture ; multi-layer SPM ; Science ; Q
    Subject code 550
    Language English
    Publishing date 2022-06-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article: Remote Sensing of Complex Permittivity and Penetration Depth of Soils Using P-Band SAR Polarimetry

    Fluhrer, Anke / Jagdhuber, Thomas / Tabatabaeenejad, Alireza / Alemohammad, Hamed / Montzka, Carsten / Friedl, Peter / Forootan, Ehsan / Kunstmann, Harald

    Remote Sensing. 2022 June 08, v. 14, no. 12

    2022  

    Abstract: A P-band SAR moisture estimation method is introduced for complex soil permittivity and penetration ... depth estimation using fully polarimetric P-band SAR signals. This method combines eigen- and model ... of vegetation types. The technique is demonstrated for airborne P-band SAR measurements acquired during the AirMOSS ...

    Abstract A P-band SAR moisture estimation method is introduced for complex soil permittivity and penetration depth estimation using fully polarimetric P-band SAR signals. This method combines eigen- and model-based decomposition techniques for separation of the total backscattering signal into three scattering components (soil, dihedral, and volume). The incorporation of a soil scattering model allows for the first time the estimation of complex soil permittivity and permittivity-based penetration depth. The proposed method needs no prior assumptions on land cover characteristics and is applicable to a variety of vegetation types. The technique is demonstrated for airborne P-band SAR measurements acquired during the AirMOSS campaign (2012–2015). The estimated complex permittivity agrees well with climate and soil conditions at different monitoring sites. Based on frequency and permittivity, P-band penetration depths vary from 5 cm to 35 cm. This value range is in accordance with previous studies in the literature. Comparison of the results is challenging due to the sparsity of vertical soil in situ sampling. It was found that the disagreement between in situ measurements and SAR-based estimates originates from the discrepancy between the in situ measuring depth of the top-soil layer (0–5 cm) and the median penetration depth of the P-band waves (24.5–27 cm).
    Keywords climate ; land cover ; models ; polarimetry ; topsoil
    Language English
    Dates of publication 2022-0608
    Publishing place Multidisciplinary Digital Publishing Institute
    Document type Article
    ZDB-ID 2513863-7
    ISSN 2072-4292
    ISSN 2072-4292
    DOI 10.3390/rs14122755
    Database NAL-Catalogue (AGRICOLA)

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  4. Article ; Online: Observation of Charge-Dependent Azimuthal Correlations in p-Pb Collisions and Its Implication for the Search for the Chiral Magnetic Effect.

    Khachatryan, V / Sirunyan, A M / Tumasyan, A / Adam, W / Asilar, E / Bergauer, T / Brandstetter, J / Brondolin, E / Dragicevic, M / Erö, J / Flechl, M / Friedl, M / Frühwirth, R / Ghete, V M / Hartl, C / Hörmann, N / Hrubec, J / Jeitler, M / König, A /
    Krätschmer, I / Liko, D / Matsushita, T / Mikulec, I / Rabady, D / Rad, N / Rahbaran, B / Rohringer, H / Schieck, J / Strauss, J / Waltenberger, W / Wulz, C-E / Dvornikov, O / Makarenko, V / Zykunov, V / Mossolov, V / Shumeiko, N / Suarez Gonzalez, J / Alderweireldt, S / De Wolf, E A / Janssen, X / Lauwers, J / Van De Klundert, M / Van Haevermaet, H / Van Mechelen, P / Van Remortel, N / Van Spilbeeck, A / Abu Zeid, S / Blekman, F / D'Hondt, J / Daci, N / De Bruyn, I / Deroover, K / Lowette, S / Moortgat, S / Moreels, L / Olbrechts, A / Python, Q / Tavernier, S / Van Doninck, W / Van Mulders, P / Van Parijs, I / Brun, H / Clerbaux, B / De Lentdecker, G / Delannoy, H / Fasanella, G / Favart, L / Goldouzian, R / Grebenyuk, A / Karapostoli, G / Lenzi, T / Léonard, A / Luetic, J / Maerschalk, T / Marinov, A / Randle-Conde, A / Seva, T / Vander Velde, C / Vanlaer, P / Vannerom, D / Yonamine, R / Zenoni, F / Zhang, F / Cimmino, A / Cornelis, T / Dobur, D / Fagot, A / Garcia, G / Gul, M / 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Ojalvo, I / Perry, T / Pierro, G A / Polese, G / Ruggles, T / Savin, A / Smith, N / Smith, W H / Taylor, D / Woods, N

    Physical review letters

    2017  Volume 118, Issue 12, Page(s) 122301

    Abstract: Charge-dependent azimuthal particle correlations with respect to the second-order event plane in p ... particles, are of similar magnitude in p-Pb and PbPb collisions at the same multiplicities. These results ...

    Abstract Charge-dependent azimuthal particle correlations with respect to the second-order event plane in p-Pb and PbPb collisions at a nucleon-nucleon center-of-mass energy of 5.02 TeV have been studied with the CMS experiment at the LHC. The measurement is performed with a three-particle correlation technique, using two particles with the same or opposite charge within the pseudorapidity range |η|<2.4, and a third particle measured in the hadron forward calorimeters (4.4<|η|<5). The observed differences between the same and opposite sign correlations, as functions of multiplicity and η gap between the two charged particles, are of similar magnitude in p-Pb and PbPb collisions at the same multiplicities. These results pose a challenge for the interpretation of charge-dependent azimuthal correlations in heavy ion collisions in terms of the chiral magnetic effect.
    Language English
    Publishing date 2017-03-24
    Publishing country United States
    Document type Journal Article
    ZDB-ID 208853-8
    ISSN 1079-7114 ; 0031-9007
    ISSN (online) 1079-7114
    ISSN 0031-9007
    DOI 10.1103/PhysRevLett.118.122301
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Measurement of prompt ψ(2S) to J/ψ yield ratios in Pb-Pb and p-p collisions at sqrt[sNN]=2.76  TeV.

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Chanon, N / Deisher, A / Dissertori, G / Dittmar, M / Donegà, M / Dünser, M / Eller, P / Grab, C / Hits, D / Lustermann, W / Mangano, B / Marini, A C / Martinez Ruiz del Arbol, P / Meister, D / Mohr, N / Nägeli, C / Nessi-Tedaldi, F / Pandolfi, F / Pauss, F / Peruzzi, M / Quittnat, M / Rebane, L / Rossini, M / Starodumov, A / Takahashi, M / Theofilatos, K / Wallny, R / Weber, H A / Amsler, C / Canelli, M F / Chiochia, V / De Cosa, A / Hinzmann, A / Hreus, T / Kilminster, B / Lange, C / Millan Mejias, B / Ngadiuba, J / Robmann, P / Ronga, F J / Taroni, S / Verzetti, M / Yang, Y / Cardaci, M / Chen, K H / Ferro, C / Kuo, C M / Lin, W / Lu, Y J / Volpe, R / Yu, S S / Chang, P / Chang, Y H / Chang, Y W / Chao, Y / Chen, K F / Chen, P H / Dietz, C / Grundler, U / Hou, W-S / Kao, K Y / Lei, Y J / Liu, Y F / Lu, R-S / Majumder, D / Petrakou, E / Tzeng, Y M / Wilken, R / Asavapibhop, B / Srimanobhas, N / Suwonjandee, N / Adiguzel, A / Bakirci, M N / Cerci, S / Dozen, C / Dumanoglu, I / Eskut, E / Girgis, S / Gokbulut, G / Gurpinar, E / Hos, I / Kangal, E E / Kayis Topaksu, A / Onengut, G / Ozdemir, K / Ozturk, S / Polatoz, A / Sogut, K / Sunar Cerci, D / Tali, B / Topakli, H / Vergili, M / Akin, I V / Bilin, B / Bilmis, S / Gamsizkan, H / Karapinar, G / Ocalan, K / Sekmen, S / Surat, U E / Yalvac, M / Zeyrek, M / Gülmez, E / Isildak, B / Kaya, M / Kaya, O / Bahtiyar, H / Barlas, E / Cankocak, K / Vardarlı, F I / Yücel, M / Levchuk, L / Sorokin, P / Brooke, J J / Clement, E / Cussans, D / Flacher, H / Frazier, R / Goldstein, J / Grimes, M / Heath, G P / Heath, H F / Jacob, J / Kreczko, L / Lucas, C / Meng, Z / Newbold, D M / Paramesvaran, S / Poll, A / Senkin, S / Smith, V J / Williams, T / Brew, C / Brown, R M / Cockerill, D J A / Coughlan, J A / Harder, K / Harper, S / Olaiya, E / Petyt, D / Shepherd-Themistocleous, C H / Thea, A / Tomalin, I R / Womersley, W J / Worm, S D / Baber, M / Bainbridge, R / Buchmuller, O / Burton, D / Colling, D / Cripps, N / Cutajar, M / 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Snook, B / Tuo, S / Velkovska, J / Arenton, M W / Boutle, S / Cox, B / Francis, B / Goodell, J / Hirosky, R / Ledovskoy, A / Li, H / Lin, C / Neu, C / Wood, J / Clarke, C / Harr, R / Karchin, P E / Kottachchi Kankanamge Don, C / Lamichhane, P / Sturdy, J / Belknap, D A / Carlsmith, D / Cepeda, M / Dasu, S / Dodd, L / Duric, S / Friis, E / Hall-Wilton, R / Herndon, M / Hervé, A / Klabbers, P / Lanaro, A / Lazaridis, C / Levine, A / Loveless, R / Mohapatra, A / Ojalvo, I / Perry, T / Pierro, G A / Polese, G / Ross, I / Sarangi, T / Savin, A / Smith, W H / Vuosalo, C / Woods, N

    Physical review letters

    2014  Volume 113, Issue 26, Page(s) 262301

    Abstract: ... measured in Pb-Pb and p-p collisions at sqrt[sNN]=2.76  TeV. The analysis is based on Pb-Pb and p-p data ... N(J/ψ))(p-p) is computed in three Pb-Pb collision centrality bins and two kinematic ranges: one ...

    Abstract The ratio between the prompt ψ(2S) and J/ψ yields, reconstructed via their decays into μ+ μ-, is measured in Pb-Pb and p-p collisions at sqrt[sNN]=2.76  TeV. The analysis is based on Pb-Pb and p-p data samples collected by CMS at the Large Hadron Collider, corresponding to integrated luminosities of 150  μb(-1) and 5.4  pb(-1), respectively. The double ratio of measured yields (Nψ(2S)/N(J/ψ))(Pb-Pb)/(Nψ(2S)/N(J/ψ))(p-p) is computed in three Pb-Pb collision centrality bins and two kinematic ranges: one at midrapidity, |y|<1.6, covering the transverse momentum range 6.5<pT<30  GeV/c, and the other at forward rapidity, 1.6<|y|<2.4, extending to lower pT values, 3<pT<30  GeV/c. The centrality-integrated double ratio changes from 0.45±0.13(stat)±0.07(syst) in the first range to 1.67±0.34(stat)±0.27(syst) in the second. This difference is most pronounced in the most central collisions.<br />
    Language English
    Publishing date 2014-12-31
    Publishing country United States
    Document type Journal Article
    ZDB-ID 208853-8
    ISSN 1079-7114 ; 0031-9007
    ISSN (online) 1079-7114
    ISSN 0031-9007
    DOI 10.1103/PhysRevLett.113.262301
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  6. Book ; Thesis: Reinigung und Rekonstitution des membrangebundenen Cytochrom P-450 abhängigen [Cytochrom-P-abhängigen] Monooxygenasesystems der Rattenleber

    Friedl, Hans-Peter

    1983  

    Title variant Reinigung und Rekonstitution des membrangebundenen Cytochrom P-450 abhängigen Monooxygenasesystems der Rattenleber
    Size III, 65 Bl. : graph. Darst.
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Ulm, Univ., Diss., 1985
    HBZ-ID HT003081697
    Database Catalogue ZB MED Medicine, Health

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  7. Article ; Online: MUTYH-associated polyposis (MAP): evidence for the origin of the common European mutations p.Tyr179Cys and p.Gly396Asp by founder events.

    Aretz, Stefan / Tricarico, Rossella / Papi, Laura / Spier, Isabel / Pin, Elisa / Horpaopan, Sukanya / Cordisco, Emanuela Lucci / Pedroni, Monica / Stienen, Dietlinde / Gentile, Annamaria / Panza, Anna / Piepoli, Ada / de Leon, Maurizio Ponz / Friedl, Waltraut / Viel, Alessandra / Genuardi, Maurizio

    European journal of human genetics : EJHG

    2013  Volume 22, Issue 7, Page(s) 923–929

    Abstract: ... the combined allele frequency of the mutations p.Tyr179Cys and p.Gly396Asp ranges between 50 and 82 ... g) by using DMLE+2.2 software. Three distinct common haplotypes, one for p.Tyr179Cys and two for p ... Gly396Asp, were identified. Estimated mutation ages were 305 g (95% CS: 271-418) for p.Tyr179Cys and 350 g ...

    Abstract MUTYH-associated polyposis (MAP) is an autosomal recessive adenomatous polyposis caused by biallelic germline mutations of the base-excision-repair gene MUTYH. In MAP patients of European origin, the combined allele frequency of the mutations p.Tyr179Cys and p.Gly396Asp ranges between 50 and 82%, while these mutations have not been identified in Far Eastern Asian populations, supporting the hypothesis that a founder effect has occurred at some point in European history. To investigate the natural history of the two common European MUTYH alleles, we genotyped six gene-flanking microsatellite markers in 80 unrelated Italian and German MAP patients segregating one or both mutations and calculated their age in generations (g) by using DMLE+2.2 software. Three distinct common haplotypes, one for p.Tyr179Cys and two for p.Gly396Asp, were identified. Estimated mutation ages were 305 g (95% CS: 271-418) for p.Tyr179Cys and 350 g (95% CS: 313-435) for p.Gly396Asp. These results provide evidence for strong founder effects and suggest that the p.Tyr179Cys and p.Gly396Asp mutations derive from ancestors who lived between 5-8 thousand years and 6-9 thousand years B.C., respectively.
    MeSH term(s) Adenomatous Polyposis Coli/genetics ; Alleles ; Animals ; DNA Glycosylases/genetics ; Female ; Founder Effect ; Gene Frequency ; Germany ; Humans ; Italy ; Male ; Mutation, Missense
    Chemical Substances DNA Glycosylases (EC 3.2.2.-) ; mutY adenine glycosylase (EC 3.2.2.-)
    Language English
    Publishing date 2013-01-30
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1141470-4
    ISSN 1476-5438 ; 1018-4813
    ISSN (online) 1476-5438
    ISSN 1018-4813
    DOI 10.1038/ejhg.2012.309
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  8. Book: 3-manifold groups are virtually residually p

    Aschenbrenner, Matthias / Friedl, Stefan

    (Memoirs of the American Mathematical Society ; 1058 = Vol. 225,3)

    2013  

    Title variant Three-manifold groups are virtually residually p
    Author's details Matthias Aschenbrenner; Stefan Friedl
    Series title Memoirs of the American Mathematical Society ; 1058 = Vol. 225,3
    Keywords Fundamental groups (Mathematics) ; Group theory ; Three-manifolds (Topology)
    Language English
    Size VII, 98 S.
    Publisher American Math. Soc
    Publishing place Providence, RI
    Document type Book
    Note "September 2013, volume 225, number 1058 (third of 4 numbers) ; Includes bibliographical references and index
    ISBN 9780821888018 ; 0821888013
    Database Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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  9. Article: Differing patterns of P-selectin expression in lung injury.

    Bless, N M / Tojo, S J / Kawarai, H / Natsume, Y / Lentsch, A B / Padgaonkar, V A / Czermak, B J / Schmal, H / Friedl, H P / Ward, P A

    The American journal of pathology

    1998  Volume 153, Issue 4, Page(s) 1113–1122

    Abstract: ... factor), we have analyzed the requirements and patterns for upregulation of lung vascular P-selectin ... In the immune complex model, upregulation of P-selectin was defined by Northern and Western blot analysis of lung ... homogenates, by immunostaining of lung tissue, and by vascular fixation of 125I-labeled anti-P-selectin. P ...

    Abstract Using two models of acute lung inflammatory injury in rats (intrapulmonary deposition of immunoglobulin G immune complexes and systemic activation of complement after infusion of purified cobra venom factor), we have analyzed the requirements and patterns for upregulation of lung vascular P-selectin. In the immune complex model, upregulation of P-selectin was defined by Northern and Western blot analysis of lung homogenates, by immunostaining of lung tissue, and by vascular fixation of 125I-labeled anti-P-selectin. P-selectin protein was detected by 1 hour (long before detection of mRNA) and expression was sustained for the next 7 hours, in striking contrast to the pattern of P-selectin expression in the cobra venom factor model, in which upregulation was very transient (within the 1st hour). In the immune complex model, injury and neutrophil accumulation were P-selectin dependent. Upregulation of P-selectin was dependent on an intact complement system, and the presence of blood neutrophils was susceptible to the antioxidant dimethyl sulfoxide and required C5a but not tumor necrosis factor alpha. In contrast, in the cobra venom factor model, upregulation of P-selectin, which is C5a dependent, was also dimethyl sulfoxide sensitive but neutrophil independent. Different mechanisms that may explain why upregulation of lung vascular P-selectin is either transient or sustained are discussed.
    MeSH term(s) Animals ; Antigen-Antibody Complex/administration & dosage ; Blotting, Northern ; Blotting, Western ; Complement C5a/deficiency ; Complement C5a/pharmacology ; Complement Inactivator Proteins/toxicity ; Dimethyl Sulfoxide/pharmacology ; Disease Models, Animal ; Elapid Venoms/pharmacology ; Immunoglobulin G/administration & dosage ; Male ; P-Selectin/genetics ; P-Selectin/metabolism ; Pulmonary Alveoli/drug effects ; Pulmonary Alveoli/metabolism ; Pulmonary Alveoli/pathology ; Pulmonary Fibrosis/chemically induced ; Pulmonary Fibrosis/metabolism ; Pulmonary Fibrosis/pathology ; RNA, Messenger/metabolism ; Rats ; Rats, Long-Evans ; Tumor Necrosis Factor-alpha/genetics ; Tumor Necrosis Factor-alpha/metabolism ; Up-Regulation
    Chemical Substances Antigen-Antibody Complex ; Complement Inactivator Proteins ; Elapid Venoms ; Immunoglobulin G ; P-Selectin ; RNA, Messenger ; Tumor Necrosis Factor-alpha ; cobra venom factor ; Complement C5a (80295-54-1) ; Dimethyl Sulfoxide (YOW8V9698H)
    Language English
    Publishing date 1998-10
    Publishing country United States
    Document type Journal Article ; Research Support, U.S. Gov't, P.H.S.
    ZDB-ID 2943-9
    ISSN 1525-2191 ; 0002-9440
    ISSN (online) 1525-2191
    ISSN 0002-9440
    DOI 10.1016/S0002-9440(10)65655-6
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  10. Article: Heterozygous PALB2 c.1592delT mutation channels DNA double-strand break repair into error-prone pathways in breast cancer patients

    Friedl, Thomas W. P. / Pospiech, Helmut

    Oncogene, 35(29):3796-806

    2015  

    Abstract: Hereditary heterozygous mutations in a variety of DNA double-strand break (DSB) repair genes have been associated with increased breast cancer risk. In the Finnish population, PALB2 (partner and localizer of BRCA2) represents a major susceptibility gene ... ...

    Institution Leibniz-Institut für Alternsforschung
    Abstract Hereditary heterozygous mutations in a variety of DNA double-strand break (DSB) repair genes have been associated with increased breast cancer risk. In the Finnish population, PALB2 (partner and localizer of BRCA2) represents a major susceptibility gene for female breast cancer, and so far, only one mutation has been described, c.1592delT, which leads to a sixfold increased disease risk. PALB2 is thought to participate in homologous recombination (HR). However, the effect of the Finnish founder mutation on DSB repair has not been investigated. In the current study, we used a panel of lymphoblastoid cell lines (LCLs) derived from seven heterozygous female PALB2 c.1592delT mutation carriers with variable health status and six wild-type matched controls. The results of our DSB repair analysis showed that the PALB2 mutation causes specific changes in pathway usage, namely increases in error-prone single-strand annealing (SSA) and microhomology-mediated end-joining (MMEJ) compared with wild-type LCLs. These data indicated haploinsufficiency regarding the suppression of error-prone DSB repair in PALB2 mutation carriers. To the contrary, neither reduced HR activities, nor impaired RAD51 filament assembly, nor sensitization to PARP inhibition were consistently observed. Expression of truncated mutant versus wild-type PALB2 verified a causal role of PALB2 c.1592delT in the shift to error-prone repair. Discrimination between healthy and malignancy-presenting PALB2 mutation carriers revealed a pathway shift particularly in the breast cancer patients, suggesting interaction of PALB2 c.1592delT with additional genomic lesions. Interestingly, the studied PALB2 mutation was associated with 53BP1 accumulation in the healthy mutation carriers but not the patients, and 53BP1 was limiting for error-prone MMEJ in patients but not in healthy carriers. Our study identified a rise in error-prone DSB repair as a potential threat to genomic integrity in heterozygous PALB2 mutation carriers. The used phenotypic marker system has the capacity to capture dysfunction caused by polygenic mechanisms and therefore offers new strategies of cancer risk prediction.
    Keywords Cancer genetics ; Cancer screening ; Epistasis ; Mechanisms of disease
    Language English
    Document type Article
    Database Repository for Life Sciences

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