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  1. Article ; Online: Caveolin-2 palmitoylation turnover facilitates insulin receptor substrate-1-directed lipid metabolism by insulin receptor tyrosine kinase.

    Choi, Moonjeong / Lee, Jaewoong / Jeong, Kyuho / Pak, Yunbae

    Biochimica et biophysica acta. Molecular basis of disease

    2024  Volume 1870, Issue 5, Page(s) 167173

    Abstract: Here, we show that insulin induces palmitoylation turnover of Caveolin-2 (Cav-2) in adipocytes. Acyl protein thioesterases-1 (APT1) catalyzes Cav-2 depalmitoylation, and zinc finger DHHC domain-containing protein palmitoyltransferase 21 (ZDHHC21) ... ...

    Abstract Here, we show that insulin induces palmitoylation turnover of Caveolin-2 (Cav-2) in adipocytes. Acyl protein thioesterases-1 (APT1) catalyzes Cav-2 depalmitoylation, and zinc finger DHHC domain-containing protein palmitoyltransferase 21 (ZDHHC21) repalmitoylation of the depalmitoylated Cav-2 for the turnover, thereby controlling insulin receptor (IR)-Cav-2-insulin receptor substrate-1 (IRS-1)-Akt-driven signaling. Insulin-induced palmitoylation turnover of Cav-2 facilitated glucose uptake and fat storage through induction of lipogenic genes. Cav-2-, APT1-, and ZDHHC21-deficient adipocytes, however, showed increased induction of lipolytic genes and glycerol release. In addition, white adipose tissues from insulin sensitive and resistant obese patients exhibited augmented expression of LYPLA1 (APT1) and ZDHHC20 (ZDHHC20). Our study identifies the specific enzymes regulating Cav-2 palmitoylation turnover, and reveals a new mechanism by which insulin-mediated lipid metabolism is controlled in adipocytes.
    Language English
    Publishing date 2024-04-16
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 60-7
    ISSN 1879-260X ; 1879-2596 ; 1872-8006 ; 1879-2642 ; 1879-2618 ; 1879-2650 ; 0006-3002 ; 0005-2728 ; 0005-2736 ; 0304-4165 ; 0167-4838 ; 1388-1981 ; 0167-4889 ; 0167-4781 ; 0304-419X ; 1570-9639 ; 0925-4439 ; 1874-9399
    ISSN (online) 1879-260X ; 1879-2596 ; 1872-8006 ; 1879-2642 ; 1879-2618 ; 1879-2650
    ISSN 0006-3002 ; 0005-2728 ; 0005-2736 ; 0304-4165 ; 0167-4838 ; 1388-1981 ; 0167-4889 ; 0167-4781 ; 0304-419X ; 1570-9639 ; 0925-4439 ; 1874-9399
    DOI 10.1016/j.bbadis.2024.167173
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Use of Drone RGB Imagery to Quantify Indicator Variables of Tropical-Forest-Ecosystem Degradation and Restoration

    Kyuho Lee / Stephen Elliott / Pimonrat Tiansawat

    Forests, Vol 14, Iss 586, p

    2023  Volume 586

    Abstract: Recognizing initial degradation levels is essential to planning effective measures to restore tropical forest ecosystems. However, measuring indicators of forest degradation is labour-intensive, time-consuming, and expensive. This study explored the use ... ...

    Abstract Recognizing initial degradation levels is essential to planning effective measures to restore tropical forest ecosystems. However, measuring indicators of forest degradation is labour-intensive, time-consuming, and expensive. This study explored the use of canopy-height models and orthophotos, derived from drone-captured RGB images, above sites at various stages of degradation in northern Thailand to quantify variables related to initial degradation levels and subsequent restoration progression. Stocking density ( R 2 = 0.71) and relative cover of forest canopy ( R 2 = 0.83), ground vegetation ( R 2 = 0.71) and exposed soil + rock ( R 2 = 0.56) correlated highly with the corresponding ground-survey data. However, mean tree height ( R 2 = 0.31) and above-ground carbon density ( R 2 = 0.45) were not well correlated. Differences in correlation strength appeared to be site-specific and related to tree size distribution, canopy openness, and soil exposure. We concluded that drone-based quantification of forest-degradation indicator variables is not yet accurate enough to replace conventional ground surveys when planning forest restoration projects. However, the development of better geo-referencing in parallel with AI systems may improve the accuracy and cost-effectiveness of drone-based techniques in the near future.
    Keywords forest degradation ; forest ecosystem restoration ; UAVs ; drones ; photogrammetry ; structure from motion ; Plant ecology ; QK900-989
    Subject code 333
    Language English
    Publishing date 2023-03-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: Development of Path Generation and Algorithm for Autonomous Combine Harvester Using Dual GPS Antenna.

    Lee, Kyuho / Choi, Hyohyuk / Kim, Junghun

    Sensors (Basel, Switzerland)

    2023  Volume 23, Issue 10

    Abstract: Research on autonomous driving technology is actively underway to solve the facing problems in the agricultural field. Combine harvesters used in East Asian countries, including Korea, are tracked-type vehicles. The steering control system of the tracked ...

    Abstract Research on autonomous driving technology is actively underway to solve the facing problems in the agricultural field. Combine harvesters used in East Asian countries, including Korea, are tracked-type vehicles. The steering control system of the tracked vehicle has different characteristics from the wheeled vehicle used in the agricultural tractor. In this paper, a dual GPS antenna-based autonomous driving system and path tracking algorithm were developed for a robot combine harvester. An α-turn-type work path generation algorithm and a path tracking algorithm were developed. The developed system and algorithm were verified through experiments using actual combine harvesters. The experiment consisted of an experiment with harvesting work and an experiment without harvesting work. In the experiment without harvesting work, an error of 0.052 m occurred during working driving and 0.207 m during turning driving. In the experiment where the harvesting work was carried out, an error of 0.038 m occurred during work driving and 0.195 m during turning driving. As a result of comparing the non-work area and driving time to the results of manual driving, the self-driving experiment with harvesting work showed an efficiency of 76.7%.
    Language English
    Publishing date 2023-05-21
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2052857-7
    ISSN 1424-8220 ; 1424-8220
    ISSN (online) 1424-8220
    ISSN 1424-8220
    DOI 10.3390/s23104944
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Use of Drone RGB Imagery to Quantify Indicator Variables of Tropical-Forest-Ecosystem Degradation and Restoration

    Lee, Kyuho / Elliott, Stephen / Tiansawat, Pimonrat

    Forests. 2023 Mar. 16, v. 14, no. 3

    2023  

    Abstract: Recognizing initial degradation levels is essential to planning effective measures to restore tropical forest ecosystems. However, measuring indicators of forest degradation is labour-intensive, time-consuming, and expensive. This study explored the use ... ...

    Abstract Recognizing initial degradation levels is essential to planning effective measures to restore tropical forest ecosystems. However, measuring indicators of forest degradation is labour-intensive, time-consuming, and expensive. This study explored the use of canopy-height models and orthophotos, derived from drone-captured RGB images, above sites at various stages of degradation in northern Thailand to quantify variables related to initial degradation levels and subsequent restoration progression. Stocking density (R² = 0.71) and relative cover of forest canopy (R² = 0.83), ground vegetation (R² = 0.71) and exposed soil + rock (R² = 0.56) correlated highly with the corresponding ground-survey data. However, mean tree height (R² = 0.31) and above-ground carbon density (R² = 0.45) were not well correlated. Differences in correlation strength appeared to be site-specific and related to tree size distribution, canopy openness, and soil exposure. We concluded that drone-based quantification of forest-degradation indicator variables is not yet accurate enough to replace conventional ground surveys when planning forest restoration projects. However, the development of better geo-referencing in parallel with AI systems may improve the accuracy and cost-effectiveness of drone-based techniques in the near future.
    Keywords carbon ; cost effectiveness ; forest canopy ; forest restoration ; ground vegetation ; orthophotography ; soil ; tree height ; tropical forests ; Thailand
    Language English
    Dates of publication 2023-0316
    Publishing place Multidisciplinary Digital Publishing Institute
    Document type Article ; Online
    ZDB-ID 2527081-3
    ISSN 1999-4907
    ISSN 1999-4907
    DOI 10.3390/f14030586
    Database NAL-Catalogue (AGRICOLA)

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  5. Article ; Online: Role of Actin-Binding Proteins in Skeletal Myogenesis.

    Nguyen, Mai Thi / Dash, Raju / Jeong, Kyuho / Lee, Wan

    Cells

    2023  Volume 12, Issue 21

    Abstract: Maintenance of skeletal muscle quantity and quality is essential to ensure various vital functions of the body. Muscle homeostasis is regulated by multiple cytoskeletal proteins and myogenic transcriptional programs responding to endogenous and exogenous ...

    Abstract Maintenance of skeletal muscle quantity and quality is essential to ensure various vital functions of the body. Muscle homeostasis is regulated by multiple cytoskeletal proteins and myogenic transcriptional programs responding to endogenous and exogenous signals influencing cell structure and function. Since actin is an essential component in cytoskeleton dynamics, actin-binding proteins (ABPs) have been recognized as crucial players in skeletal muscle health and diseases. Hence, dysregulation of ABPs leads to muscle atrophy characterized by loss of mass, strength, quality, and capacity for regeneration. This comprehensive review summarizes the recent studies that have unveiled the role of ABPs in actin cytoskeletal dynamics, with a particular focus on skeletal myogenesis and diseases. This provides insight into the molecular mechanisms that regulate skeletal myogenesis via ABPs as well as research avenues to identify potential therapeutic targets. Moreover, this review explores the implications of non-coding RNAs (ncRNAs) targeting ABPs in skeletal myogenesis and disorders based on recent achievements in ncRNA research. The studies presented here will enhance our understanding of the functional significance of ABPs and mechanotransduction-derived myogenic regulatory mechanisms. Furthermore, revealing how ncRNAs regulate ABPs will allow diverse therapeutic approaches for skeletal muscle disorders to be developed.
    MeSH term(s) Microfilament Proteins/metabolism ; Actins/metabolism ; Mechanotransduction, Cellular ; Muscle, Skeletal/metabolism ; RNA, Untranslated/metabolism ; Muscle Development/genetics
    Chemical Substances Microfilament Proteins ; Actins ; RNA, Untranslated
    Language English
    Publishing date 2023-10-25
    Publishing country Switzerland
    Document type Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 2661518-6
    ISSN 2073-4409 ; 2073-4409
    ISSN (online) 2073-4409
    ISSN 2073-4409
    DOI 10.3390/cells12212523
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Correction: Long-term prognostic factors for cardiovascular events in patients with chest pain without diabetes mellitus nor significant coronary stenosis.

    Rha, Seung-Woon / Lee, Kyuho / Choi, Se Yeon / Byun, Jae Kyeong / Cha, Jinah / Hyun, Sujin / Ahn, Woo Jin / Park, Soohyung / Kang, Dong Oh / Park, Eun Jin / Choi, Cheol Ung / Choi, Byoung Geol

    Heart and vessels

    2024  Volume 39, Issue 5, Page(s) 392

    Language English
    Publishing date 2024-03-29
    Publishing country Japan
    Document type Published Erratum
    ZDB-ID 89678-0
    ISSN 1615-2573 ; 0910-8327 ; 0935-736X
    ISSN (online) 1615-2573
    ISSN 0910-8327 ; 0935-736X
    DOI 10.1007/s00380-024-02391-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2049: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  7. Book: Strategic winery tourism and management

    Lee, Kyuho

    building competitive winery tourism and winery management strategy

    (Advances in hospitality and tourism book series)

    2016  

    Author's details ed. by Kyuho Lee
    Series title Advances in hospitality and tourism book series
    Keywords Wine tourism ; Wineries ; Tourismus ; Wein ; Weinbau ; Tourismuswirtschaft ; Tourismusmarketing
    Language English
    Size XVI, 298 S., Ill., graph. Darst.
    Publisher Apple Academic Press u.a.
    Publishing place Oakville u.a.
    Document type Book
    Note Enth. 15 Beitr.
    ISBN 1926895681 ; 9781482223415 ; 9781926895680 ; 1482223414
    Database ECONomics Information System

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  8. Article ; Online: Aging in Place With a Spouse in Need: Neighborhood Cohesion and Older Adult Spouses' Physical and Mental Health.

    Lee, Kyuho / Marier, Patrik

    International journal of aging & human development

    2020  Volume 93, Issue 4, Page(s) 1012–1030

    Abstract: This study examines the association of perceived neighborhood cohesion (NC) with older adults' health and the buffering effects of NC against the negative effects of spousal caregiving on health. Data of 3329 community-living older adults living with a ... ...

    Abstract This study examines the association of perceived neighborhood cohesion (NC) with older adults' health and the buffering effects of NC against the negative effects of spousal caregiving on health. Data of 3329 community-living older adults living with a spouse in need of care from the Health and Retirement Study were collected at two time-points. Multiple regression analyses were computed for each of the four health outcomes. For men, NC predicted fewer depressive symptoms and better cognition. NC buffered the negative effect of providing activities of daily living (ADL) help to the wife on cognition. For women, NC predicted fewer depressive symptoms and better cognition. NC buffered the negative effect of providing ADL help to the husband on ADL difficulties. The results accentuate the importance of residency location for older adults' physical and mental health. The health benefits of NC may have more implications for older adults providing spousal care.
    MeSH term(s) Activities of Daily Living ; Aged ; Caregivers ; Female ; Humans ; Independent Living ; Male ; Mental Health ; Spouses
    Language English
    Publishing date 2020-11-26
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 187072-5
    ISSN 1541-3535 ; 0091-4150
    ISSN (online) 1541-3535
    ISSN 0091-4150
    DOI 10.1177/0091415020974616
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1113: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (1.OG)
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  9. Article ; Online: Large-scale efficient mid-wave infrared optoelectronics based on black phosphorus ink.

    Gupta, Niharika / Wang, Shu / Higashitarumizu, Naoki / Wang, Vivian / Lee, Kyuho / Park, Cheolmin / Javey, Ali

    Science advances

    2023  Volume 9, Issue 49, Page(s) eadi9384

    Abstract: The mid-wave infrared (MWIR), ranging from 2 to 5 micrometers, is of substantial interest for chemical sensing, imaging, and spectroscopy. Black phosphorus (bP)-based MWIR light emitters and detectors have been shown to outperform the state-of-the-art ... ...

    Abstract The mid-wave infrared (MWIR), ranging from 2 to 5 micrometers, is of substantial interest for chemical sensing, imaging, and spectroscopy. Black phosphorus (bP)-based MWIR light emitters and detectors have been shown to outperform the state-of-the-art for commercial devices due to the low Auger recombination coefficient of bP. However, the scalability of these devices remains a challenge. Here, we report a bP ink formula that preserves the exceptional MWIR optoelectronic properties of bP to deposit centimeter-scale, uniform, and pinhole free films with a photoluminescence quantum yield higher than competing III-V and II-VI semiconductors with similar bandgaps at high excitation regime. As a proof of concept, we use bP ink as a "phosphor" on a red commercial light-emitting diode to demonstrate bright MWIR light emission. We also show that these films can be integrated into heterostructure device architectures with electron and hole selective contacts for direct-injected light emission and detection in MWIR.
    Language English
    Publishing date 2023-12-08
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2810933-8
    ISSN 2375-2548 ; 2375-2548
    ISSN (online) 2375-2548
    ISSN 2375-2548
    DOI 10.1126/sciadv.adi9384
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  10. Article ; Online: Corrigendum to "TMBIM6 deficiency leads to bone loss by accelerating osteoclastogenesis" [Redox Biol. 64 (2023) 102804].

    Yi, Sun-Ju / Jang, You-Jee / Lee, Seokchan / Cho, Sung-Jin / Kang, Kyuho / Park, Jae-Il / Chae, Han-Jung / Kim, Hyung-Ryong / Kim, Kyunghwan

    Redox biology

    2023  Volume 66, Page(s) 102844

    Language English
    Publishing date 2023-08-15
    Publishing country Netherlands
    Document type Published Erratum
    ZDB-ID 2701011-9
    ISSN 2213-2317 ; 2213-2317
    ISSN (online) 2213-2317
    ISSN 2213-2317
    DOI 10.1016/j.redox.2023.102844
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