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  1. Article ; Online: A Man With Sound- and Pressure-Induced Vertigo.

    Wade, Christian I / Jensen, Maxwell C / Ruhl, Douglas S

    Annals of emergency medicine

    2023  Volume 82, Issue 3, Page(s) 403–407

    MeSH term(s) Humans ; Male ; Vertigo/etiology ; Sound/adverse effects ; Pressure/adverse effects
    Language English
    Publishing date 2023-08-18
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 603080-4
    ISSN 1097-6760 ; 0196-0644
    ISSN (online) 1097-6760
    ISSN 0196-0644
    DOI 10.1016/j.annemergmed.2023.04.014
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    Zs.A 1344: Show issues Location:
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  2. Article ; Online: Oral isotretinoin: 29 years of medical malpractice cases in the United States.

    Martell, David W / Ruhl, Douglas S

    Journal of the American Academy of Dermatology

    2021  Volume 85, Issue 2, Page(s) 404–408

    Abstract: Background: Reviews of malpractice claims in the United States show trends of increasing payments with statistically higher payouts for more debilitating and permanent injuries.: Objectives: To examine lawsuits involving notable associated adverse ... ...

    Abstract Background: Reviews of malpractice claims in the United States show trends of increasing payments with statistically higher payouts for more debilitating and permanent injuries.
    Objectives: To examine lawsuits involving notable associated adverse reactions of isotretinoin.
    Methods: Court records of US legal trials from 1985 to 2014 were obtained from a major computerized database: LexisNexis. Data were compiled on the demographics of the defendant and plaintiff, litigation over adverse drug reaction, legal allegations, verdicts, and ruling decisions.
    Results: Seventy unique cases met inclusion criteria and were selected for review. Forty-four cases cited physicians, and 26 cited a pharmaceutical company. When data from physician and pharmaceutical company litigations were combined, individuals 17 years or younger were more likely to be granted litigation outcomes in their favor compared with adults (P = .0016). Cases alleging failure to monitor were associated with an outcome in favor of the plaintiff (P = .0379).
    Limitations: Cases settled or terminated before going to court could not be reviewed.
    Conclusions: Familiarity with malpractice trends through precedent-setting cases will increase physician awareness of common pitfalls, potentially mitigating litigation risk and improving patient care.
    MeSH term(s) Administration, Oral ; Dermatologic Agents/administration & dosage ; Dermatologic Agents/adverse effects ; Humans ; Isotretinoin/administration & dosage ; Isotretinoin/adverse effects ; Malpractice/statistics & numerical data ; Time Factors ; United States
    Chemical Substances Dermatologic Agents ; Isotretinoin (EH28UP18IF)
    Language English
    Publishing date 2021-06-12
    Publishing country United States
    Document type Journal Article
    ZDB-ID 603641-7
    ISSN 1097-6787 ; 0190-9622
    ISSN (online) 1097-6787
    ISSN 0190-9622
    DOI 10.1016/j.jaad.2016.12.025
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Non-lethal outcomes of engaging regulated cell death pathways in cancer.

    Kalkavan, Halime / Rühl, Sebastian / Shaw, Jeremy J P / Green, Douglas R

    Nature cancer

    2023  Volume 4, Issue 6, Page(s) 795–806

    Abstract: Regulated cell death (RCD) is essential for successful systemic cancer therapy. Yet, the engagement of RCD pathways does not inevitably result in cell death. Instead, RCD pathways can take part in diverse biological processes if the cells survive. ... ...

    Abstract Regulated cell death (RCD) is essential for successful systemic cancer therapy. Yet, the engagement of RCD pathways does not inevitably result in cell death. Instead, RCD pathways can take part in diverse biological processes if the cells survive. Consequently, these surviving cells, for which we propose the term 'flatliners', harbor important functions. These evolutionarily conserved responses can be exploited by cancer cells to promote their own survival and growth, with challenges and opportunities for cancer therapy.
    MeSH term(s) Regulated Cell Death ; Cell Death/genetics ; Neoplasms/genetics
    Language English
    Publishing date 2023-06-05
    Publishing country England
    Document type Journal Article ; Review ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ISSN 2662-1347
    ISSN (online) 2662-1347
    DOI 10.1038/s43018-023-00571-6
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  4. Article ; Online: An Example of Employing the Principles of Bioethics to Medical Decision Making in the COVID-19 Era.

    Ruhl, Douglas S / Hohman, Marc H

    The Laryngoscope

    2020  Volume 130, Issue 11, Page(s) 2688–2689

    MeSH term(s) Anti-Inflammatory Agents/therapeutic use ; Antiviral Agents/therapeutic use ; Bell Palsy/drug therapy ; Bell Palsy/virology ; Bioethics ; COVID-19/complications ; COVID-19/drug therapy ; Clinical Decision-Making/ethics ; Decision Making, Shared ; Female ; Humans ; Middle Aged ; Prednisone/therapeutic use ; SARS-CoV-2 ; Valacyclovir/therapeutic use
    Chemical Substances Anti-Inflammatory Agents ; Antiviral Agents ; Valacyclovir (MZ1IW7Q79D) ; Prednisone (VB0R961HZT)
    Keywords covid19
    Language English
    Publishing date 2020-08-13
    Publishing country United States
    Document type Case Reports
    ZDB-ID 80180-x
    ISSN 1531-4995 ; 0023-852X
    ISSN (online) 1531-4995
    ISSN 0023-852X
    DOI 10.1002/lary.28896
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  6. Article ; Online: An Example of Employing the Principles of Bioethics to Medical Decision Making in the COVID ‐19 Era

    Ruhl, Douglas S. / Hohman, Marc H.

    The Laryngoscope

    2020  Volume 130, Issue 11, Page(s) 2688–2689

    Keywords Otorhinolaryngology ; covid19
    Language English
    Publisher Wiley
    Publishing country us
    Document type Article ; Online
    ZDB-ID 80180-x
    ISSN 1531-4995 ; 0023-852X
    ISSN (online) 1531-4995
    ISSN 0023-852X
    DOI 10.1002/lary.28896
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  7. Article ; Online: Atresiaplasty in Congenital Aural Atresia: What the Facial Plastic Surgeon Needs to Know.

    Ruhl, Douglas S / Kesser, Bradley W

    Facial plastic surgery clinics of North America

    2017  Volume 26, Issue 1, Page(s) 87–96

    Abstract: Patients with microtia and congenital aural atresia should have a comprehensive hearing assessment early in life. Options for hearing habilitation should be presented, and children with bilateral aural atresia should be fitted with a bone conducting ... ...

    Abstract Patients with microtia and congenital aural atresia should have a comprehensive hearing assessment early in life. Options for hearing habilitation should be presented, and children with bilateral aural atresia should be fitted with a bone conducting hearing device to support normal speech and language development. If atresia surgery is pursued, the microtia surgeon must be aware of certain principles. This article presents recommendations on options for potentially improving hearing in children with congenital aural atresia: assessing surgical candidacy; chronology and timing of surgeries; functional importance of certain ear structures; and understanding the possible locations of an aberrant facial nerve to avoid injury in these patients.
    MeSH term(s) Cartilage, Articular/surgery ; Congenital Abnormalities/surgery ; Congenital Abnormalities/therapy ; Ear/abnormalities ; Ear/surgery ; Ear, External/surgery ; Hearing Loss/rehabilitation ; Hearing Loss/therapy ; Humans ; Reconstructive Surgical Procedures/methods ; Ribs/transplantation ; Surgery, Plastic ; Transplantation, Autologous
    Language English
    Publishing date 2017-08-12
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 1315178-2
    ISSN 1558-1926 ; 1064-7406
    ISSN (online) 1558-1926
    ISSN 1064-7406
    DOI 10.1016/j.fsc.2017.09.005
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  8. Article ; Online: Medical Malpractice Implications of Clinical Practice Guidelines.

    Ruhl, Douglas S / Siegal, Gil

    Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery

    2017  Volume 157, Issue 2, Page(s) 175–177

    Abstract: Clinical practice guidelines aim to improve medical care by clarifying and making useful recommendations to providers. Although providers should account for patients' unique characteristics when determining a treatment plan, it is generally perceived as ... ...

    Abstract Clinical practice guidelines aim to improve medical care by clarifying and making useful recommendations to providers. Although providers should account for patients' unique characteristics when determining a treatment plan, it is generally perceived as good practice to follow guidelines when applicable. This is of interest in malpractice litigation, where it is essential to establish a standard of care to evaluate the performances of providers. Although the opinions of expert witnesses are used to determine standards of care, guidelines are expected to play a leading role. Guidelines alone should not establish a legal standard but may help inform this discussion in the courtroom. Therefore, it is incumbent that excellent, practical, and timely guidelines are continually created and updated in a transparent way. These guidelines must be very clear and underscore the various strengths of recommendation based on the quality of available evidence.
    MeSH term(s) Conflict of Interest ; Malpractice/legislation & jurisprudence ; Practice Guidelines as Topic ; Societies, Medical ; United States
    Language English
    Publishing date 2017-08
    Publishing country England
    Document type Journal Article
    ZDB-ID 392085-9
    ISSN 1097-6817 ; 0161-6439 ; 0194-5998
    ISSN (online) 1097-6817
    ISSN 0161-6439 ; 0194-5998
    DOI 10.1177/0194599817707943
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  9. Article ; Online: The COVID-19 Airway Management Isolation Chamber (CAMIC) for Ears.

    Tolisano, Anthony M / Blood, Timothy C / Riley, Charles A / Ruhl, Douglas S / Hong, Steven S

    The Laryngoscope

    2020  Volume 130, Issue 11, Page(s) 2690–2692

    MeSH term(s) Adult ; Airway Management/instrumentation ; Airway Management/methods ; COVID-19/prevention & control ; COVID-19/transmission ; Cholesteatoma, Middle Ear/surgery ; Disease Transmission, Infectious/prevention & control ; Humans ; Male ; Otologic Surgical Procedures/adverse effects ; Otologic Surgical Procedures/instrumentation ; Otologic Surgical Procedures/methods ; Patient Isolators/virology ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-08-20
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 80180-x
    ISSN 1531-4995 ; 0023-852X
    ISSN (online) 1531-4995
    ISSN 0023-852X
    DOI 10.1002/lary.28942
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  10. Article ; Online: Updates in medical malpractice: an otology perspective.

    Ruhl, Douglas S / Littlefield, Philip D

    Current opinion in otolaryngology & head and neck surgery

    2015  Volume 23, Issue 5, Page(s) 348–354

    Abstract: Purpose of review: Most surgeons at some point are involved in a medical malpractice case. There has been an increase in the number of manuscripts that analyse malpractice databases and insurance claims, as well as commentaries on the current ... ...

    Abstract Purpose of review: Most surgeons at some point are involved in a medical malpractice case. There has been an increase in the number of manuscripts that analyse malpractice databases and insurance claims, as well as commentaries on the current medicolegal climate recently. This manuscript broadly reviews articles of interest to all providers and then focuses on malpractice in otology.
    Recent findings: Medical malpractice articles (particularly topics related to otologic surgery published within the last 1-2 years) were searched. The growing body of literature can be divided into the themes of general negligence, mitigating injuries and the use of clinical practice guidelines in the courtroom as guidance for expert witnesses.
    Summary: Recent findings suggest that the frequency of malpractice claims may be decreasing. Hearing loss and facial nerve injury are the most common injuries associated with otologic surgery. These injuries can be costly when negligence is found. Clinic practice guidelines are slowly being used as evidence in the courtroom and there are established guidelines that an expert witness must follow should a surgeon be called to give testimony.
    MeSH term(s) Expert Testimony ; Humans ; Malpractice/legislation & jurisprudence ; Malpractice/statistics & numerical data ; Otolaryngology/legislation & jurisprudence ; Otolaryngology/statistics & numerical data ; Otologic Surgical Procedures/adverse effects ; Otologic Surgical Procedures/legislation & jurisprudence ; Otologic Surgical Procedures/statistics & numerical data
    Language English
    Publishing date 2015-10
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 1232518-1
    ISSN 1531-6998 ; 1068-9508
    ISSN (online) 1531-6998
    ISSN 1068-9508
    DOI 10.1097/MOO.0000000000000182
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