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  1. Article ; Online: Diagnostic & Therapeutic Challenges.

    Wu, Jing / Chen, Yanli / Feng, Liwen / Liu, Shaozhang / Liu, Wei

    Retina (Philadelphia, Pa.)

    2024  

    Language English
    Publishing date 2024-03-22
    Publishing country United States
    Document type Journal Article
    ZDB-ID 603192-4
    ISSN 1539-2864 ; 0275-004X
    ISSN (online) 1539-2864
    ISSN 0275-004X
    DOI 10.1097/IAE.0000000000004110
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: A critical review on BDE-209

    Yuqiong Sun / Yanli Xu / Haodi Wu / Jing Hou

    Environment International, Vol 183, Iss , Pp 108410- (2024)

    Source, distribution, influencing factors, toxicity, and degradation

    2024  

    Abstract: As the most widely used polybrominated diphenyl ether, BDE-209 is commonly used in polymer-based commercial and household products. Due to its unique physicochemical properties, BDE-209 is ubiquitous in a variety of environmental compartments and can be ... ...

    Abstract As the most widely used polybrominated diphenyl ether, BDE-209 is commonly used in polymer-based commercial and household products. Due to its unique physicochemical properties, BDE-209 is ubiquitous in a variety of environmental compartments and can be exposed to organisms in various ways and cause toxic effects. The present review outlines the current state of knowledge on the occurrence of BDE-209 in the environment, influencing factors, toxicity, and degradation. BDE-209 has been detected in various environmental matrices including air, soil, water, and sediment. Additionally, environmental factors such as organic matter, total suspended particulate, hydrodynamic, wind, and temperature affecting BDE-209 are specifically discussed. Toxicity studies suggest BDE-209 may cause systemic toxic effects on living organisms, reproductive toxicity, embryo-fetal toxicity, genetic toxicity, endocrine toxicity, neurotoxicity, immunotoxicity, and developmental toxicity, or even be carcinogenic. BDE-209 has toxic effects on organisms mainly through epigenetic regulation and induction of oxidative stress. Evidence regarding the degradation of BDE-209, including biodegradation, photodegradation, Fenton degradation, zero-valent iron degradation, chemical oxidative degradation, and microwave radiation degradation is summarized. This review may contribute to assessing the environmental risks of BDE-209 to help develop rational management plans.
    Keywords Electronic waste ; Soil and sediment ; Reproductive toxicity ; Genetic toxicity ; Biodegradation ; Abiotic degradation ; Environmental sciences ; GE1-350
    Subject code 590
    Language English
    Publishing date 2024-01-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article: Impact of Treatment Delay on the Prognosis of Patients with Ovarian Cancer: A Population-based Study Using the Surveillance, Epidemiology, and End Results Database.

    Zhao, Jing / Chen, Ruiying / Zhang, Yanli / Wang, Yu / Zhu, Haiyan

    Journal of Cancer

    2024  Volume 15, Issue 2, Page(s) 473–483

    Abstract: Purpose: ...

    Abstract Purpose:
    Language English
    Publishing date 2024-01-01
    Publishing country Australia
    Document type Journal Article
    ZDB-ID 2573318-7
    ISSN 1837-9664
    ISSN 1837-9664
    DOI 10.7150/jca.87881
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Phthalates contamination in sediments: A review of sources, influencing factors, benthic toxicity, and removal strategies.

    Xu, Yanli / Sun, Yuqiong / Lei, Ming / Hou, Jing

    Environmental pollution (Barking, Essex : 1987)

    2024  Volume 344, Page(s) 123389

    Abstract: Sediments provide habitat and food for benthos, and phthalates (PAEs) have been detected in numerous river and marine sediments as a widely used plastic additive. PAEs in sediments is not only toxic to benthos, but also poses a threat to pelagic fish and ...

    Abstract Sediments provide habitat and food for benthos, and phthalates (PAEs) have been detected in numerous river and marine sediments as a widely used plastic additive. PAEs in sediments is not only toxic to benthos, but also poses a threat to pelagic fish and human health through the food chain, so it is essential to comprehensively assess the contamination of sediments with PAEs. This paper presents a critical evaluation of PAEs in sediments, which is embodied in the analysis of the sources of PAEs in sediments from multiple perspectives. Biological production is indispensable, while artificial synthesis is the most dominant, thus the focus was on analyzing the industrial and commercial sources of synthetic PAEs. In addition, since the content of PAEs in sediments varies, some factors affecting the content of PAEs in sediments are summarized, such as the properties of PAEs, the properties of plastics, and environmental factors (sediments properties and hydrodynamic conditions). As endocrine disruptors, PAEs can produce toxicity to its direct contacts. Therefore, the effects of PAEs on benthos immunity, endocrinology, reproduction, development, and metabolism were comprehensively analyzed. In addition, we found that reciprocal inhibition and activation of the systems lead to genotoxicity and apoptosis. Finally, the paper discusses the feasible measures to control PAEs in wastewater and leachate from the perspective of source control, and summarizes the in-situ treatment measures for PAEs contamination in sediments. This paper provides a comprehensive review of PAEs contamination in sediments, toxic effects and removal strategies, and provides an important reference for reducing the contamination and toxicity of PAEs to benthos.
    MeSH term(s) Animals ; Humans ; Apoptosis ; DNA Damage ; Drug Contamination ; Endocrine Disruptors/toxicity ; Food ; Phthalic Acids/toxicity ; Esters ; China
    Chemical Substances Endocrine Disruptors ; Phthalic Acids ; Esters
    Language English
    Publishing date 2024-01-19
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 280652-6
    ISSN 1873-6424 ; 0013-9327 ; 0269-7491
    ISSN (online) 1873-6424
    ISSN 0013-9327 ; 0269-7491
    DOI 10.1016/j.envpol.2024.123389
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: miR-186-5p improves alveolar epithelial barrier function by targeting the wnt5a/β-catenin signaling pathway in sepsis-acute lung injury.

    Li, Mei / Yang, Jing / Wu, Yanli / Ma, Xigang

    International immunopharmacology

    2024  Volume 131, Page(s) 111864

    Abstract: Background: Alveolar epithelial barrier dysfunction is one of the pathological features of sepsis-acute lung injury(ALI). However, the molecular mechanisms that regulate the function of alveolar epithelial barrier remain unclear. This study aimed to ... ...

    Abstract Background: Alveolar epithelial barrier dysfunction is one of the pathological features of sepsis-acute lung injury(ALI). However, the molecular mechanisms that regulate the function of alveolar epithelial barrier remain unclear. This study aimed to determine the regulatory role of miR-186-5p in alveolar epithelial barrier function in sepsis-ALI and its underlying molecular mechanism.
    Methods: We established sepsis-ALI models in vivo and in vitro, detected the miR-186-5p and wnt5a/β-catenin expressions, and observed the functional changes of the alveolar epithelial barrier by miR-186-5p overexpression. We used rescue experiments to clarify whether miR-186-5p works through wnt5a/β-catenin.
    Results: miR-186-5p expression was decreased, wnt5a expression was increased, and the wnt5a/β-catenin signaling pathway was activated in mouse lung tissues and A549 cells after inflammatory stimulation. miR-186-5p overexpression resulted in wnt5a/β-catenin signaling pathway inhibition, decreased apoptosis in A549 cells, improved alveolar epithelial barrier function, reduced lung tissue injury in ALI mice, decreased IL-6 and TNF-α levels, and increased claudin4 and ZO-1 expression. Using miRNA-related database prediction and dual-luciferase reporter gene analysis, the targeting relationship between miR-186-5p and wnt5a was determined. The protective effect produced by miR-186-5p overexpression on the alveolar barrier was reversed after the application of the wnt5a/β-catenin activator Licl.
    Conclusion: Our experimental data suggest miR-186-5p targets the wnt5a/β-catenin pathway, thereby regulating alveolar epithelial barrier function. Furthermore, both miR-186-5p and wnt5a/β-catenin are potential therapeutic targets that could impact sepsis-ALI.
    MeSH term(s) Mice ; Animals ; beta Catenin/metabolism ; Acute Lung Injury/drug therapy ; Signal Transduction ; MicroRNAs/genetics ; MicroRNAs/metabolism ; Sepsis/genetics
    Chemical Substances beta Catenin ; MicroRNAs
    Language English
    Publishing date 2024-03-13
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2043785-7
    ISSN 1878-1705 ; 1567-5769
    ISSN (online) 1878-1705
    ISSN 1567-5769
    DOI 10.1016/j.intimp.2024.111864
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Corrigendum: Identifying neutrophil-associated subtypes in ulcerative colitis and confirming neutrophils promote colitis-associated colorectal cancer.

    Zhang, Chen / Zhang, Jiantao / Zhang, Yanli / Song, Zian / Bian, Jing / Yi, Huanfa / Ma, Zhanchuan

    Frontiers in immunology

    2024  Volume 15, Page(s) 1376797

    Abstract: This corrects the article DOI: 10.3389/fimmu.2023.1095098.]. ...

    Abstract [This corrects the article DOI: 10.3389/fimmu.2023.1095098.].
    Language English
    Publishing date 2024-04-10
    Publishing country Switzerland
    Document type Published Erratum
    ZDB-ID 2606827-8
    ISSN 1664-3224 ; 1664-3224
    ISSN (online) 1664-3224
    ISSN 1664-3224
    DOI 10.3389/fimmu.2024.1376797
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Case report

    Yanli Cao / Peijun Liu / Qiuling Song / Jing Wang

    Frontiers in Medicine, Vol

    A case of sepsis caused by rickettsial infection-induced hemophagocytic syndrome

    2023  Volume 10

    Abstract: Hemophagocytic lymphohistiocytosis (HLH) is a rare histiocytic disorder characterized by reactive hyperplasia of the mononuclear phagocytic system, which is primarily caused by dysfunction of cytotoxic killer cells and natural killer cells, leading to ... ...

    Abstract Hemophagocytic lymphohistiocytosis (HLH) is a rare histiocytic disorder characterized by reactive hyperplasia of the mononuclear phagocytic system, which is primarily caused by dysfunction of cytotoxic killer cells and natural killer cells, leading to antigen clearance barriers and the overactivation of the mononuclear phagocytic system due to continuous antigen stimulation. HLH encompasses a group of clinical syndromes marked by the overproduction of inflammatory cytokines. A 68-year-old Chinese man presented with persistent fever, chills, nausea, and vomiting; the patient had no history of any underlying conditions. Laboratory investigations revealed decreased levels of red blood cells, white blood cells, and platelets, along with reduced natural killer cell activity, increased CD25, hyperferritinemia, and the detection of Rickettsia DNA in his blood, meeting the diagnostic criteria of the Histiocyte Society HLH-2004 guidelines. The patient was treated with antibiotics, improving anemia, glucocorticoid therapy, and continuous renal replacement therapy (CRRT), temporarily improving his condition. However, the patient died after 2 years from chronic renal failure caused by septic shock.
    Keywords Rickettsia ; sepsis ; multiple organ dysfunction ; hemophagocytic syndrome ; immune imbalance ; Medicine (General) ; R5-920
    Subject code 610
    Language English
    Publishing date 2023-08-01T00:00:00Z
    Publisher Frontiers Media S.A.
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article ; Online: Oxymatrine Alleviates Collagen-Induced Arthritis in Mice by Regulating the Immune Balance of T Cells.

    Cao, Gan / Li, Jing / Mao, Zhuhan / Zhang, Yanli

    Molecules (Basel, Switzerland)

    2023  Volume 28, Issue 15

    Abstract: Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by systemic immunity and autoimmune disorders. We have previously found that oxymatrine (OMT), a natural alkaloid, can alleviate rheumatoid arthritis without knowing whether OMT can ... ...

    Abstract Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by systemic immunity and autoimmune disorders. We have previously found that oxymatrine (OMT), a natural alkaloid, can alleviate rheumatoid arthritis without knowing whether OMT can alleviate rheumatoid arthritis through gut microbiota. In this study, we found that OMT can alleviate collagen-induced arthritis in mice and reconstruct the immune balance of Th1/Th2, Treg/Th17, and Tfr/Tfh cells. Colon transcriptome gene enrichment analysis indicated that oxymatrine may alleviate collagen induced arthritis in mice through immune system process pathway. Furthermore, OMT significantly altered the gut microbiota variety, changed the composition of microbial colonies, and reshaped the gut microbiota of collagen-induced arthritis (CIA) mice, which may participate in the regulation of the balance of Th1/Th2, Treg/Th17, and Tfr/Tfh cells to alleviate collagen-induced arthritis in mice.
    MeSH term(s) Mice ; Animals ; Arthritis, Experimental/metabolism ; T-Lymphocytes, Regulatory ; Arthritis, Rheumatoid/chemically induced ; Arthritis, Rheumatoid/drug therapy ; Autoimmune Diseases/metabolism ; Th17 Cells ; Alkaloids/pharmacology ; Alkaloids/metabolism ; Cytokines/metabolism
    Chemical Substances oxymatrine (85U4C366QS) ; Alkaloids ; Cytokines
    Language English
    Publishing date 2023-08-04
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 1413402-0
    ISSN 1420-3049 ; 1431-5165 ; 1420-3049
    ISSN (online) 1420-3049
    ISSN 1431-5165 ; 1420-3049
    DOI 10.3390/molecules28155879
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Case report: A case of sepsis caused by rickettsial infection-induced hemophagocytic syndrome.

    Cao, Yanli / Liu, Peijun / Song, Qiuling / Wang, Jing

    Frontiers in medicine

    2023  Volume 10, Page(s) 1209174

    Abstract: Hemophagocytic lymphohistiocytosis (HLH) is a rare histiocytic disorder characterized by reactive hyperplasia of the mononuclear phagocytic system, which is primarily caused by dysfunction of cytotoxic killer cells and natural killer cells, leading to ... ...

    Abstract Hemophagocytic lymphohistiocytosis (HLH) is a rare histiocytic disorder characterized by reactive hyperplasia of the mononuclear phagocytic system, which is primarily caused by dysfunction of cytotoxic killer cells and natural killer cells, leading to antigen clearance barriers and the overactivation of the mononuclear phagocytic system due to continuous antigen stimulation. HLH encompasses a group of clinical syndromes marked by the overproduction of inflammatory cytokines. A 68-year-old Chinese man presented with persistent fever, chills, nausea, and vomiting; the patient had no history of any underlying conditions. Laboratory investigations revealed decreased levels of red blood cells, white blood cells, and platelets, along with reduced natural killer cell activity, increased CD25, hyperferritinemia, and the detection of Rickettsia DNA in his blood, meeting the diagnostic criteria of the Histiocyte Society HLH-2004 guidelines. The patient was treated with antibiotics, improving anemia, glucocorticoid therapy, and continuous renal replacement therapy (CRRT), temporarily improving his condition. However, the patient died after 2 years from chronic renal failure caused by septic shock.
    Language English
    Publishing date 2023-08-07
    Publishing country Switzerland
    Document type Case Reports
    ZDB-ID 2775999-4
    ISSN 2296-858X
    ISSN 2296-858X
    DOI 10.3389/fmed.2023.1209174
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Recent Progresses in Pyrolysis of Plastic Packaging Wastes and Biomass Materials for Conversion of High-Value Carbons: A Review.

    Cheng, Youliang / Wang, Jinpeng / Fang, Changqing / Du, Yanli / Su, Jian / Chen, Jing / Zhang, Yingshuan

    Polymers

    2024  Volume 16, Issue 8

    Abstract: The recycling of plastic packaging wastes helps to alleviate the problems of white pollution and resource shortage. It is very necessary to develop high-value conversion technologies for plastic packaging wastes. To our knowledge, carbon materials with ... ...

    Abstract The recycling of plastic packaging wastes helps to alleviate the problems of white pollution and resource shortage. It is very necessary to develop high-value conversion technologies for plastic packaging wastes. To our knowledge, carbon materials with excellent properties have been widely used in energy storage, adsorption, water treatment, aerospace and functional packaging, and so on. Waste plastic packaging and biomass materials are excellent precursor materials of carbon materials due to their rich sources and high carbon content. Thus, the conversion from waste plastic packaging and biomass materials to carbon materials attracts much attention. However, closely related reviews are lacking up to now. In this work, the pyrolysis routes of the pyrolysis of plastic packaging wastes and biomass materials for conversion to high-value carbons and the influence factors were analyzed. Additionally, the applications of these obtained carbons were summarized. Furthermore, the limitations of the current pyrolysis technology are put forward and the research prospects are forecasted. Therefore, this review can provide a useful reference and guide for the research on the pyrolysis of plastic packaging wastes and biomass materials and the conversion to high-value carbon.
    Language English
    Publishing date 2024-04-11
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2527146-5
    ISSN 2073-4360 ; 2073-4360
    ISSN (online) 2073-4360
    ISSN 2073-4360
    DOI 10.3390/polym16081066
    Database MEDical Literature Analysis and Retrieval System OnLINE

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