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Article ; Online: Critique on: "Dose-response associations of dietary inflammatory potential with health outcomes: a prospective cohort study of 198,265 UK biobank participants".

Faheem, M Anas / Azeem, Bazil / Khan, Ayesha

2024 Volume 49, Issue 5, Page(s) 102479

MeSH term(s)	Humans ; Prospective Studies ; Biological Specimen Banks ; UK Biobank ; Diet ; Risk Factors
Language	English
Publishing date	2024-03-02
Publishing country	Netherlands
Document type	Letter
ZDB-ID	441230-8
ISSN	1535-6280 ; 0146-2806
ISSN (online)	1535-6280
ISSN	0146-2806
DOI	10.1016/j.cpcardiol.2024.102479
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Article ; Online: Dual-3DM

Khan, Arfat Ahmad / Mahendran, Rakesh Kumar / Perumal, Kumar / Faheem, Muhammad

IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society

2024 Volume 32, Page(s) 696–707

Abstract: Alzheimer's Disease (AD) is a widespread, chronic, irreversible, and degenerative condition, and its early detection during the prodromal stage is of utmost importance. Typically, AD studies rely on single data modalities, such as MRI or PET, for making ... ...

Abstract	Alzheimer's Disease (AD) is a widespread, chronic, irreversible, and degenerative condition, and its early detection during the prodromal stage is of utmost importance. Typically, AD studies rely on single data modalities, such as MRI or PET, for making predictions. Nevertheless, combining metabolic and structural data can offer a comprehensive perspective on AD staging analysis. To address this goal, this paper introduces an innovative multi-modal fusion-based approach named as Dual-3DM3-AD. This model is proposed for an accurate and early Alzheimer's diagnosis by considering both MRI and PET image scans. Initially, we pre-process both images in terms of noise reduction, skull stripping and 3D image conversion using Quaternion Non-local Means Denoising Algorithm (QNLM), Morphology function and Block Divider Model (BDM), respectively, which enhances the image quality. Furthermore, we have adapted Mixed-transformer with Furthered U-Net for performing semantic segmentation and minimizing complexity. Dual-3DM3-AD model is consisted of multi-scale feature extraction module for extracting appropriate features from both segmented images. The extracted features are then aggregated using Densely Connected Feature Aggregator Module (DCFAM) to utilize both features. Finally, a multi-head attention mechanism is adapted for feature dimensionality reduction, and then the softmax layer is applied for multi-class Alzheimer's diagnosis. The proposed Dual-3DM3-AD model is compared with several baseline approaches with the help of several performance metrics. The final results unveil that the proposed work achieves 98% of accuracy, 97.8% of sensitivity, 97.5% of specificity, 98.2% of f-measure, and better ROC curves, which outperforms other existing models in multi-class Alzheimer's diagnosis.
MeSH term(s)	Humans ; Alzheimer Disease/diagnostic imaging ; Semantics ; Magnetic Resonance Imaging/methods ; Algorithms ; Positron-Emission Tomography/methods
Language	English
Publishing date	2024-02-08
Publishing country	United States
Document type	Journal Article
ZDB-ID	1166307-8
ISSN	1558-0210 ; 1063-6528 ; 1534-4320
ISSN (online)	1558-0210
ISSN	1063-6528 ; 1534-4320
DOI	10.1109/TNSRE.2024.3357723
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Article ; Online: Addressing The Alarming Surge Of Naegleria And Other Water-Borne Diseases In Karachi: A Call For Urgent Action.

Khan, Najam Ahmed / Faheem, Anas / Imtiaz, Hania / Ismail, Muhammad / Mughal, Sanila

Journal of Ayub Medical College, Abbottabad : JAMC

2024 Volume 35Suppl 1, Issue 4, Page(s) S813–S815

MeSH term(s)	Humans ; Naegleria ; Water ; Naegleria fowleri
Chemical Substances	Water (059QF0KO0R)
Language	English
Publishing date	2024-02-26
Publishing country	Pakistan
Document type	Journal Article
ZDB-ID	2192473-9
ISSN	1819-2718 ; 1025-9589
ISSN (online)	1819-2718
ISSN	1025-9589
DOI	10.55519/JAMC-S4-12371
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Article: Incidence of Sheath Blight in Irrigated Rice and Associated Yield Losses in Northern India.

Ahamad, Faheem / Khan, Mujeebur Rahman

Plant disease

2023 Volume 107, Issue 10, Page(s) 2907–2915

Abstract: Rice-growing districts in Uttar Pradesh, India, were surveyed during the months of July and October to record the frequency of occurrence and disease incidence of sheath blight caused ... ...

Abstract	Rice-growing districts in Uttar Pradesh, India, were surveyed during the months of July and October to record the frequency of occurrence and disease incidence of sheath blight caused by
MeSH term(s)	Oryza ; Incidence ; Plant Diseases ; India ; Soil
Chemical Substances	Soil
Language	English
Publishing date	2023-10-25
Publishing country	United States
Document type	Journal Article
ZDB-ID	754182-x
ISSN	0191-2917
ISSN	0191-2917
DOI	10.1094/PDIS-12-22-2905-RE
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Article ; Online: Nitroreduction of flutamide by

Khan, Mohd Faheem / Murphy, Cormac D

Biochemistry and biophysics reports

2022 Volume 29, Page(s) 101209

Abstract: The microbial model of mammalian drug metabolism, ...

Abstract	The microbial model of mammalian drug metabolism,
Language	English
Publishing date	2022-01-17
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	2831046-9
ISSN	2405-5808 ; 2405-5808
ISSN (online)	2405-5808
ISSN	2405-5808
DOI	10.1016/j.bbrep.2022.101209
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Article ; Online: Effect Of Perineural Administration Of Dexmedetomidine With Bupivacaine Versus Bupivacaine Alone In Ultrasound Guided Supraclavicular Block For Upper Extremity Orthopaedic Operations.

Khan, Maliha Khalid / Hafeez, Amran / Feroze, Faheem / Tahir, Anjum Atique / Abbasi, Shehzad / Faheem, Muhammad Shaheer Bin / Farooq, Saeed

Journal of Ayub Medical College, Abbottabad : JAMC

2024 Volume 35, Issue 3, Page(s) 384–389

Abstract: Background: During procedures on the upper limbs, the brachial plexus block is usually advised. To increase the length of the block, many medicines have been utilized as adjuvants. The purpose of this study was to compare the effects of dexmedetomidine ... ...

Abstract	Background: During procedures on the upper limbs, the brachial plexus block is usually advised. To increase the length of the block, many medicines have been utilized as adjuvants. The purpose of this study was to compare the effects of dexmedetomidine plus bupivacaine against bupivacaine alone on the onset and duration of the sensory and motor block and the duration of analgesia in the supraclavicular block during upper extremity orthopaedic surgery. Methods: Sixty individuals qualified for orthopaedic operations on the upper extremities, ranging in age from 20 to 60 years, participated in this prospective, randomized investigation. The modified Bromage scale and the pinprick method were used to assess the sensory and motor block. Using a visual analogue pain scale, the postoperative pain was evaluated at 0, 6, 12 and 24 hours after surgery. Results: In patients receiving only bupivacaine, the mean onset time of sensory and motor block was 32.84 minutes and 26.67 minutes respectively; while in those receiving bupivacaine along with dexmedetomidine, it was 23.38 minutes and 14.81 minutes (p<0.005). In the intervention group (bupivacaine and dexmedetomidine), the period between the first request for analgesia and the duration period of sensory and motor block were both longer (p<0.005). The intervention group experienced less postoperative discomfort for 24 hours (p<0.05). Conclusions: Dexmedetomidine added to bupivacaine perineurally prolonged both numbness and immobility while shortening the time it took for sensory and motor blocks to begin. Moreover, dexmedetomidine considerably decreased postoperative pain when combined with bupivacaine for supraclavicular blocks.
MeSH term(s)	Adult ; Humans ; Middle Aged ; Young Adult ; Anesthetics, Local ; Brachial Plexus Block/methods ; Bupivacaine/therapeutic use ; Dexmedetomidine/therapeutic use ; Orthopedics ; Pain, Postoperative/drug therapy ; Pain, Postoperative/prevention & control ; Prospective Studies ; Ultrasonography, Interventional ; Upper Extremity/surgery
Chemical Substances	Anesthetics, Local ; Bupivacaine (Y8335394RO) ; Dexmedetomidine (67VB76HONO)
Language	English
Publishing date	2024-02-26
Publishing country	Pakistan
Document type	Journal Article ; Randomized Controlled Trial
ZDB-ID	2192473-9
ISSN	1819-2718 ; 1025-9589
ISSN (online)	1819-2718
ISSN	1025-9589
DOI	10.55519/JAMC-03-12044
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Article ; Online: Comparison Of Hemodynamic Effect Caused By Intrathecal Low Dose Administration Of 0.5% Against 0.75% Hyperbaric Bupivacaine In Patients Undergoing Lower Limb Surgery Under Unilateral Spinal Anaesthesia.

Khan, Maliha Khalid / Hafiz, Amran / Feroze, Faheem / Tahir, Anjum Atique / Farooq, Saeed / Shaheer Bin Faheem, Muhammad

Journal of Ayub Medical College, Abbottabad : JAMC

2024 Volume 35, Issue 4, Page(s) 549–552

Abstract: Background: Spinal anaesthesia has its unique place in modern anaesthetic practice. In past, most of the surgeries, irrespective of the site of surgery, were performed in general anaesthesia but now in the modern anaesthetic field, spinal anaesthesia ... ...

Abstract	Background: Spinal anaesthesia has its unique place in modern anaesthetic practice. In past, most of the surgeries, irrespective of the site of surgery, were performed in general anaesthesia but now in the modern anaesthetic field, spinal anaesthesia has markedly replaced general anaesthesia, specifically in obstetrics, lower limbs, and abdominal surgeries. Methods: A total of 100 patients fit to undergo lower limb surgery between the ages of 20 to 70 years were included in the study. 50 patients were in 0.5% hyperbaric bupivacaine (Group A) while 50 patients were in the 0.75% hyperbaric bupivacaine group (Group B). Patients with a history of allergies to local anaesthetics, ischemic heart disease and contraindications to spinal anaesthesia were excluded. At the end of the injection, the patient was immediately laid down and tilted to 30 degrees lateral on the operative side for unilateral anaesthesia. Mean arterial pressure at baseline, 15, 30, 45 and 60 minutes was recorded by trainee anaesthesia. A baseline was taken of mean arterial pressure measured 15 minutes before induction of spinal anaesthesia in a lying position. Results: The mean baseline arterial pressure of patients in group A was 88.72±1.71 mmHg and in group B was 88.94±1.95 mmHg. Mean arterial pressure MAP at 15, 30, 45 and 60 minutes in both groups was as follows; 86.22±2.55 vs 81.78±1.52 mmHg, 83.72±3.36 vs 75.84±1.34 mmHg, 80.02±3.40 vs 70.90±0.97 mmHg and 77.14±4.24 vs 66.06±1.62 mmHg respectively (p-value <0.05). Conclusions: This study concluded that the hemodynamic parameters in terms of mean arterial pressure remained more stable by deviating less from the baseline value with the use of a low dose of 0.5% hyperbaric bupivacaine instead of 0.75% hyperbaric bupivacaine in patients undergoing lower limb surgery under unilateral spinal anaesthesia.
MeSH term(s)	Pregnancy ; Female ; Humans ; Young Adult ; Adult ; Middle Aged ; Aged ; Bupivacaine ; Anesthesia, Spinal ; Anesthetics, Local ; Hemodynamics ; Lower Extremity/surgery
Chemical Substances	Bupivacaine (Y8335394RO) ; Anesthetics, Local
Language	English
Publishing date	2024-02-26
Publishing country	Pakistan
Document type	Journal Article
ZDB-ID	2192473-9
ISSN	1819-2718 ; 1025-9589
ISSN (online)	1819-2718
ISSN	1025-9589
DOI	10.55519/JAMC-04-12270
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Article ; Online: Ethosomes: a potential nanovesicular carrier to enhancing the drug delivery against skin barriers.

Hameed, Huma / Faheem, Saleha / Khan, Mahtab Ahmad / Hameed, Anam / Ereej, Nelofer / Ihsan, Hafsa

Journal of microencapsulation

2024 Volume 41, Issue 3, Page(s) 204–225

Abstract: Ethosomes, which are liposomes like structures, mainly composed primarily of ethanol, have attracted considerable attention due to their potential to enhance the drug permeation via skin. The article discusses the formulation and preparation methods of ... ...

Abstract	Ethosomes, which are liposomes like structures, mainly composed primarily of ethanol, have attracted considerable attention due to their potential to enhance the drug permeation via skin. The article discusses the formulation and preparation methods of ethosomes, offering insights into the various factors that influence their size, shape, and stability. Moreover, it explores the techniques used to assess the physicochemical properties of ethosomes and their impact on drug delivery effectiveness. The article also elucidates the mechanism by which ethosomes enhance skin permeation, emphasising their ability to modify the lipid structure and fluidity of the stratum corneum. Additionally, the review investigates the applications of ethosomes in diverse drug delivery scenarios, including the delivery of small molecules, peptides, and phytoconstituents. It highlights the potential of ethosomes to improve drug bioavailability, extend drug release, and achieve targeted delivery to specific skin layers or underlying tissues.
MeSH term(s)	Skin Absorption ; Administration, Cutaneous ; Skin/metabolism ; Drug Delivery Systems/methods ; Liposomes/chemistry ; Drug Carriers/chemistry
Chemical Substances	Liposomes ; Drug Carriers
Language	English
Publishing date	2024-03-08
Publishing country	England
Document type	Journal Article ; Review
ZDB-ID	843632-0
ISSN	1464-5246 ; 0265-2048
ISSN (online)	1464-5246
ISSN	0265-2048
DOI	10.1080/02652048.2024.2326085
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Article ; Online: Comment on: Prognostic Value Of Liver Damage Assessed Through Direct Bilirubin Levels And Skeleton Muscle Weakness In Patients With Heart Failure.

Khan, Asfia Faheem / Kumar, Satesh / Samiullah, Fnu

Current problems in cardiology

2023 Volume 48, Issue 11, Page(s) 101872

Language	English
Publishing date	2023-06-09
Publishing country	Netherlands
Document type	Letter
ZDB-ID	441230-8
ISSN	1535-6280 ; 0146-2806
ISSN (online)	1535-6280
ISSN	0146-2806
DOI	10.1016/j.cpcardiol.2023.101872
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Article ; Online: Cyberattack patterns in blockchain-based communication networks for distributed renewable energy systems: A study on big datasets.

Faheem, Muhammad / Al-Khasawneh, Mahmoud Ahmad / Khan, Arfat Ahmad / Madni, Syed Hamid Hussain

Data in brief

2024 Volume 53, Page(s) 110212

Abstract: Blockchain-based reliable, resilient, and secure communication for Distributed Energy Resources (DERs) is essential in Smart Grid (SG). The Solana blockchain, due to its high stability, scalability, and throughput, along with low latency, is envisioned ... ...

Abstract	Blockchain-based reliable, resilient, and secure communication for Distributed Energy Resources (DERs) is essential in Smart Grid (SG). The Solana blockchain, due to its high stability, scalability, and throughput, along with low latency, is envisioned to enhance the reliability, resilience, and security of DERs in SGs. This paper presents big datasets focusing on SQL Injection, Spoofing, and Man-in-the-Middle (MitM) cyberattacks, which have been collected from Solana blockchain-based Industrial Wireless Sensor Networks (IWSNs) for events monitoring and control in DERs. The datasets provided include both raw (unprocessed) and refined (processed) data, which highlight distinct trends in cyberattacks in DERs. These distinctive patterns demonstrate problems like superfluous mass data generation, transmitting invalid packets, sending deceptive data packets, heavily using network bandwidth, rerouting, causing memory overflow, overheads, and creating high latency. These issues result in ineffective real-time events monitoring and control of DERs in SGs. The thorough nature of these datasets is expected to play a crucial role in identifying and mitigating a wide range of cyberattacks across different smart grid applications.
Language	English
Publishing date	2024-02-22
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	2786545-9
ISSN	2352-3409 ; 2352-3409
ISSN (online)	2352-3409
ISSN	2352-3409
DOI	10.1016/j.dib.2024.110212
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