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  1. Article: Editorial: Medication safety in COVID-19 management, Volume II.

    Das, Saibal

    Frontiers in pharmacology

    2023  Volume 14, Page(s) 1175152

    Language English
    Publishing date 2023-03-09
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2587355-6
    ISSN 1663-9812
    ISSN 1663-9812
    DOI 10.3389/fphar.2023.1175152
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Editorial: Medication Safety in COVID-19 Management.

    Das, Saibal

    Frontiers in pharmacology

    2022  Volume 13, Page(s) 940307

    Language English
    Publishing date 2022-07-08
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2587355-6
    ISSN 1663-9812
    ISSN 1663-9812
    DOI 10.3389/fphar.2022.940307
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Performance in a Balance Test and Prediction of All-Cause Mortality in Community-Dwelling Elderly Ambulatory Individuals: A Systematic Review and Meta-analysis.

    Das, Saibal / Bagepally, Bhavani S / Eerike, Madhavi / Cherian, Jerin J / Dasgupta, Shreyashi / Mathews, George / Rao, Shailaja

    Research on aging

    2024  , Page(s) 1640275241232392

    Abstract: Objective: ...

    Abstract Objective:
    Language English
    Publishing date 2024-02-09
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 424452-7
    ISSN 1552-7573 ; 0164-0275
    ISSN (online) 1552-7573
    ISSN 0164-0275
    DOI 10.1177/01640275241232392
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: The epidemiological and mycological profile of superficial mycoses in india from 2015 to 2021

    Saibal Das / Sanjib Bandyopadhyay / Sanket Sawant / Sirshendu Chaudhuri

    Indian Journal of Public Health, Vol 67, Iss 1, Pp 123-

    A systematic review

    2023  Volume 135

    Abstract: Background: The epidemiological and mycological patterns of superficial mycoses across various geographic regions of India across the last few years are changing. Objective: This study was performed to evaluate the epidemiological and mycological profile ...

    Abstract Background: The epidemiological and mycological patterns of superficial mycoses across various geographic regions of India across the last few years are changing. Objective: This study was performed to evaluate the epidemiological and mycological profile of superficial mycoses in India between 2015 and 2021. Methods: In this systematic review, the PubMed database was searched for all observational studies published between January 1, 2015, and December 31, 2021, which had evaluated the clinico-mycological profile of superficial mycoses among outpatients from various parts of India. Descriptive statistics was used to represent the results. Results: Forty studies (21 from the north, three from the northeast, five from the east, seven from the south, one from the west, and three from multiple regions of India) were included. Male patients and those of the age group of 21–40 years were most commonly affected. The proportion of dermatophytes as causative organisms was consistently high across all regions and throughout the study period (23.6%–100%). Among dermatophytes, the proportion of Trichophyton mentagrophyte (14.0%–97.2%) and Trichophyton rubrum (0%–69.1%) was consistently high across all regions. The prevalence of T. mentagrophyte showed a rising trend, while that T. rubrum showed a declining trend from 2015 to 2021. Conclusions: The epidemiological and mycological pattern of superficial mycoses showed a fairly similar trend across various regions of India from 2015 to 2021. Dermatophytes were the main causative agents of superficial mycoses; the most common species were T. mentagrophyte and T. rubrum. A rising trend of T. Mentagrophyte infection was found.
    Keywords dermatophytosis ; epidemiological ; india ; mycological ; superficial mycoses ; trichophyton mentagrophyte ; Public aspects of medicine ; RA1-1270
    Subject code 950
    Language English
    Publishing date 2023-01-01T00:00:00Z
    Publisher Wolters Kluwer Medknow Publications
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article ; Online: Effects of saroglitazar in the treatment of non-alcoholic fatty liver disease or non-alcoholic steatohepatitis: A systematic review and meta-analysis.

    Bandyopadhyay, Sanjay / Samajdar, Shambo Samrat / Das, Saibal

    Clinics and research in hepatology and gastroenterology

    2023  Volume 47, Issue 7, Page(s) 102174

    Abstract: Aim: This systematic review and meta-analysis was conducted to evaluate the efficacy and safety of 4 mg saroglitazar treatment in patients with non-alcoholic fatty liver disease (NAFLD) or non-alcoholic steatohepatitis (NASH).: Methods: PubMed, ... ...

    Abstract Aim: This systematic review and meta-analysis was conducted to evaluate the efficacy and safety of 4 mg saroglitazar treatment in patients with non-alcoholic fatty liver disease (NAFLD) or non-alcoholic steatohepatitis (NASH).
    Methods: PubMed, Embase, Scopus, Cochrane CENTRAL, medRxiv (pre-print), bioRxiv (pre-print), and ClinicalTrials.gov databases were searched for relevant studies. The primary outcome was the change in the serum alanine transaminase (ALT) level. The secondary outcomes were changes in liver stiffness, liver function test parameters, and metabolic parameters. Pooled mean differences were calculated using random-effects models.
    Results: Of 331 studies that were screened, ten were included. Treatment with adjunct saroglitazar showed a reduction in ALT [mean difference: 26.01 U/L (95% CI: 10.67 to 41.35); p = 0.009; i
    Conclusion: Treatment with adjunct 4 mg saroglitazar could significantly improve liver enzymes, reduce liver stiffness, and improve metabolic parameters (serum glucose and lipid profile) in patients with NAFLD or NASH.
    MeSH term(s) Humans ; Non-alcoholic Fatty Liver Disease ; Pyrroles/therapeutic use ; Pyrroles/metabolism ; Pyrroles/pharmacology ; Phenylpropionates/therapeutic use ; Phenylpropionates/metabolism ; Phenylpropionates/pharmacology ; Liver Function Tests ; Alanine Transaminase ; Liver/metabolism
    Chemical Substances saroglitazar (E0YMX3S4JD) ; Pyrroles ; Phenylpropionates ; Alanine Transaminase (EC 2.6.1.2)
    Language English
    Publishing date 2023-06-26
    Publishing country France
    Document type Meta-Analysis ; Systematic Review ; Journal Article
    ZDB-ID 2594333-9
    ISSN 2210-741X ; 2210-7401
    ISSN (online) 2210-741X
    ISSN 2210-7401
    DOI 10.1016/j.clinre.2023.102174
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: The epidemiological and mycological profile of superficial mycoses in india from 2015 to 2021: A systematic review.

    Das, Saibal / Bandyopadhyay, Sanjib / Sawant, Sanket / Chaudhuri, Sirshendu

    Indian journal of public health

    2023  Volume 67, Issue 1, Page(s) 123–135

    Abstract: Background: The epidemiological and mycological patterns of superficial mycoses across various geographic regions of India across the last few years are changing.: Objective: This study was performed to evaluate the epidemiological and mycological ... ...

    Abstract Background: The epidemiological and mycological patterns of superficial mycoses across various geographic regions of India across the last few years are changing.
    Objective: This study was performed to evaluate the epidemiological and mycological profile of superficial mycoses in India between 2015 and 2021.
    Methods: In this systematic review, the PubMed database was searched for all observational studies published between January 1, 2015, and December 31, 2021, which had evaluated the clinico-mycological profile of superficial mycoses among outpatients from various parts of India. Descriptive statistics was used to represent the results.
    Results: Forty studies (21 from the north, three from the northeast, five from the east, seven from the south, one from the west, and three from multiple regions of India) were included. Male patients and those of the age group of 21-40 years were most commonly affected. The proportion of dermatophytes as causative organisms was consistently high across all regions and throughout the study period (23.6%-100%). Among dermatophytes, the proportion of Trichophyton mentagrophyte (14.0%-97.2%) and Trichophyton rubrum (0%-69.1%) was consistently high across all regions. The prevalence of T. mentagrophyte showed a rising trend, while that T. rubrum showed a declining trend from 2015 to 2021.
    Conclusions: The epidemiological and mycological pattern of superficial mycoses showed a fairly similar trend across various regions of India from 2015 to 2021. Dermatophytes were the main causative agents of superficial mycoses; the most common species were T. mentagrophyte and T. rubrum. A rising trend of T. Mentagrophyte infection was found.
    MeSH term(s) Humans ; Male ; Young Adult ; Adult ; India/epidemiology ; Dermatomycoses/epidemiology ; Prevalence ; Databases, Factual
    Language English
    Publishing date 2023-01-10
    Publishing country India
    Document type Systematic Review ; Journal Article
    ZDB-ID 800737-8
    ISSN 2229-7693 ; 0019-557X
    ISSN (online) 2229-7693
    ISSN 0019-557X
    DOI 10.4103/ijph.ijph_987_22
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Acylsilane Directed Rh-Catalyzed Arene C-H Alkylation with Maleimides and Visible-Light-Induced Siloxycarbene-Amide Cyclization: [3 + 2] Carbo-Annulation in Ru Catalysis.

    Vaggu, Raju / Thadem, Nagender / Rajesh, Manda / Grée, René / Das, Saibal

    Organic letters

    2023  Volume 25, Issue 15, Page(s) 2594–2599

    Abstract: We herein demonstrate the acylsilane-directed Rh-catalyzed arene C-H bond alkylation with maleimides. The resulting derivatives were utilized in visible-light-induced intramolecular siloxycarbene-amide cyclization for the synthesis of new tricyclic γ- ... ...

    Abstract We herein demonstrate the acylsilane-directed Rh-catalyzed arene C-H bond alkylation with maleimides. The resulting derivatives were utilized in visible-light-induced intramolecular siloxycarbene-amide cyclization for the synthesis of new tricyclic γ-lactams. In parallel, we also harnessed the same acylsilane and maleimide units through [3 + 2] carbo-annulation by using Ru-catalysis. A wide range of maleimides and aroylsilanes were used to establish the broadness of these transformations.
    Language English
    Publishing date 2023-04-10
    Publishing country United States
    Document type Journal Article
    ISSN 1523-7052
    ISSN (online) 1523-7052
    DOI 10.1021/acs.orglett.3c00487
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Seroprevalence and Dynamics of anti-SARS-CoV-2 antibody among healthcare workers following ChAdOx1 nCoV-19 vaccination.

    Sarkar, Soma / Das, Shantanab / Choudhury, Kabita / Mukherjee, Saibal / Chatterjee, Raghunath

    Epidemiology and infection

    2022  , Page(s) 1–20

    Language English
    Publishing date 2022-04-25
    Publishing country England
    Document type Journal Article
    ZDB-ID 632982-2
    ISSN 1469-4409 ; 0950-2688
    ISSN (online) 1469-4409
    ISSN 0950-2688
    DOI 10.1017/S0950268822000747
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Synthesis of bridgehead-azacycles

    Thadem, Nagender / Rajesh, Manda / Balaboina, Harikrishna / Das, Saibal

    Organic & biomolecular chemistry

    2022  Volume 20, Issue 32, Page(s) 6368–6383

    Abstract: The synthesis of various bridged azacyclic adducts has recently become a reemerging topic due to their bioactive and natural product mimic profiles. Accordingly, herein, we report a method for easy access to succinamide-bridged azacyclic derivatives ... ...

    Abstract The synthesis of various bridged azacyclic adducts has recently become a reemerging topic due to their bioactive and natural product mimic profiles. Accordingly, herein, we report a method for easy access to succinamide-bridged azacyclic derivatives through the metal-free polarization-controlled dual C-N/C-C annulation of readily available α-amino acids, 2-amino benzaldehydes or pyrrole/indole-2-aldehyde and maleimide substrates. This cascade features a rare dipolarophile-induced diastereo-selective amidative annulation, followed by 3 + 2 cycloaddition as key steps.
    MeSH term(s) Aldehydes/chemistry ; Amino Acids ; Biological Products ; Cycloaddition Reaction ; Maleimides/chemistry
    Chemical Substances Aldehydes ; Amino Acids ; Biological Products ; Maleimides
    Language English
    Publishing date 2022-08-17
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2097583-1
    ISSN 1477-0539 ; 1477-0520
    ISSN (online) 1477-0539
    ISSN 1477-0520
    DOI 10.1039/d2ob01117d
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Role of semaglutide in the treatment of nonalcoholic fatty liver disease or non-alcoholic steatohepatitis: A systematic review and meta-analysis.

    Bandyopadhyay, Sanjay / Das, Saibal / Samajdar, Shambo Samrat / Joshi, Shashank R

    Diabetes & metabolic syndrome

    2023  Volume 17, Issue 10, Page(s) 102849

    Abstract: Aim: This systematic review and meta-analysis was conducted to evaluate the efficacy and safety of 24 weeks of semaglutide treatment in patients with non-alcoholic fatty liver disease (NAFLD) or non-alcoholic steatohepatitis (NASH).: Methods: PubMed, ...

    Abstract Aim: This systematic review and meta-analysis was conducted to evaluate the efficacy and safety of 24 weeks of semaglutide treatment in patients with non-alcoholic fatty liver disease (NAFLD) or non-alcoholic steatohepatitis (NASH).
    Methods: PubMed, Embase, Scopus, Cochrane CENTRAL, and ClinicalTrials.gov databases were searched for relevant studies. The primary outcome was the change in the serum alanine transaminase level. The secondary outcomes were changes in liver stiffness, liver function test parameters, metabolic parameters, and safety. Pooled mean differences and relative risks were calculated using random-effects models.
    Results: Six hundred studies were screened and eight were included (n = 2413). Semaglutide treatment showed a reduction in serum alanine transaminase [mean difference: 14.07 U/L (95% CI: 19.39 to -8.75); p < 0.001] and aspartate transaminase [mean difference: 6.89 U/L (95% CI: 9.14 to -4.63); p < 0.001] levels. There was a significant improvement in liver fat content [mean difference: 4.97% (95% CI: 6.65 to -3.29); p < 0.001] and liver stiffness [mean difference: 0.96 kPa (95% CI: 1.87 to -0.04); p = 0.04]. There were significant improvements in the glycated hemoglobin level and the lipid profile. However, the risk of serious adverse events [relative risk: 1.54 (95% CI: 1.02 to 2.34); p = 0.04] was high following semaglutide treatment as compared to placebo; the most common ones were gastrointestinal (nausea and vomiting, dyspepsia, decreased appetite, constipation, and diarrhea) and gallbladder-related diseases.
    Conclusion: Treatment with 24 weeks of semaglutide could significantly improve liver enzymes, reduce liver stiffness, and improve metabolic parameters in patients with NAFLD/NASH. However, the gastrointestinal adverse effects could be a major concern.
    MeSH term(s) Humans ; Non-alcoholic Fatty Liver Disease/metabolism ; Alanine Transaminase ; Liver/metabolism ; Glucagon-Like Peptides/therapeutic use
    Chemical Substances semaglutide (53AXN4NNHX) ; Alanine Transaminase (EC 2.6.1.2) ; Glucagon-Like Peptides (62340-29-8)
    Language English
    Publishing date 2023-09-13
    Publishing country Netherlands
    Document type Meta-Analysis ; Systematic Review ; Journal Article ; Review
    ZDB-ID 2273766-2
    ISSN 1878-0334 ; 1871-4021
    ISSN (online) 1878-0334
    ISSN 1871-4021
    DOI 10.1016/j.dsx.2023.102849
    Database MEDical Literature Analysis and Retrieval System OnLINE

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