LIVIVO - Search results -

Search results

Result 1 - 10 of total 65

Search options

Article ; Online: Rheumatology in Cameroon: History, Challenges, and Future.

Nkeck, Jan René / Pelda, Adeline / Singwé, Madeleine Ngandeu

2024 Volume 51, Issue 3, Page(s) 313

MeSH term(s)	Humans ; Cameroon/epidemiology ; Rheumatology
Language	English
Publishing date	2024-03-01
Publishing country	Canada
Document type	Journal Article
ZDB-ID	194928-7
ISSN	1499-2752 ; 0315-162X
ISSN (online)	1499-2752
ISSN	0315-162X
DOI	10.3899/jrheum.2023-0955
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 1168: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (1.OG) ab Jg. 2022: Lesesaal (EG)
Zs.MO 135: Show issues

Order via subito

This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Epidemiology of thromboembolic events in children and adolescents with antiphospholipid syndrome: A systematic review with meta-analysis.

Essouma, Mickael / Nkeck, Jan Rene / Noubiap, Jean Jacques

Reumatologia clinica

2024 Volume 20, Issue 3, Page(s) 155–161

Abstract: Background and aim: This was a systematic review and meta-analysis of the prevalence of thromboembolic events in children and adolescents with antiphospholipid syndrome (APS).: Methods: We searched PubMed, EMBASE and Web of Science to select relevant ...

Abstract	Background and aim: This was a systematic review and meta-analysis of the prevalence of thromboembolic events in children and adolescents with antiphospholipid syndrome (APS). Methods: We searched PubMed, EMBASE and Web of Science to select relevant articles published between 1 January 2000 and 27 February 2022. We used the random-effects meta-analysis to estimate pooled point prevalence rates of thromboembolic events in studies with a minimum sample size of 30. Results: We included five studies reporting data of 336 children and adolescents with primary APS and secondary APS (SAPS). Pooled point prevalence rates of initial general thrombosis, arterial thrombosis, venous thrombosis and stroke in individuals with seropositive APS were 98.2% (95% confidence interval [CI] 87.5-100), 27.6% (95% CI 21.4-34.2), 51.1% (95% CI 38.2-63.9) and 13.4% 95% CI (6.3-22.7), respectively. Pooled point prevalence rates of initial arterial and venous thromboses in children and adolescents with SAPS were 45.7% (95% CI 21.1-71.6) and 29.2% (95% CI 14.8-46), respectively. Conclusion: Arterio-venous thromboembolism is highly frequent in children and adolescents with SAPS. More studies using thrombotic and non-thrombotic APS classification criteria are warranted to better assess the frequency and predictors of thromboembolism in age- and ancestry-diverse pediatric populations affected by different types of APS.
MeSH term(s)	Child ; Humans ; Adolescent ; Antiphospholipid Syndrome/complications ; Antiphospholipid Syndrome/epidemiology ; Thrombosis ; Venous Thrombosis ; Venous Thromboembolism/epidemiology ; Venous Thromboembolism/etiology
Language	English
Publishing date	2024-02-21
Publishing country	Spain
Document type	Meta-Analysis ; Systematic Review ; Journal Article ; Review
ISSN	2173-5743
ISSN (online)	2173-5743
DOI	10.1016/j.reumae.2023.10.005
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article ; Online: MCP-1-2518 (A>G) polymorphism and asthma risk: a pilot case-control study in Cameroon.

Nkeck, Jériel Pascal / Nkeck, Jan René / Chedjou, Jean-Paul / Ndoadoumgue, Aude Laetitia / Essama, Doris Bibi / Afane Ze, Emmanuel / Mbacham, Wilfred Fon

The Pan African medical journal

2023 Volume 44, Page(s) 166

Abstract: Introduction: there is little data on the genetic determinants of asthma in Cameroon and sub-Saharan Africa, yet the involvement of genetics in the pathogenesis of this disease has been reported in the literature for several years. This study aims to ... ...

Abstract	Introduction: there is little data on the genetic determinants of asthma in Cameroon and sub-Saharan Africa, yet the involvement of genetics in the pathogenesis of this disease has been reported in the literature for several years. This study aims to investigate the possible role of MCP-1 2518 for the risk of asthma in Cameroonians. Methods: we performed a case-control study on 30 volunteers suffering from asthma, matched by aged and sex to 30 healthy subjects. We determine the polymorphism of MCP-1 2518 using restriction fragment length polymorphism following Polymerase Chain Reaction (RFLP-PCR). Fisher exact test was used to compare proportions, with a threshold of significance set at 0.05. Results: the average age of cases was 21±10 years with 17 (56.7%) females. The distribution of the MCP-1-2518 (A>G) gene polymorphism in people with asthma was as follows: 3 for AA, 5 for GG, and 22 for AG. The minor G allele was predominant (90%) in people with asthma. It was significantly associated with asthma whether the genotype was heterozygous AG or homozygous GG (p<0.01). Conclusion: MCP-1-2518 (A>G) shows an association with asthma in our sample. Future larger studies evaluating several polymorphisms are needed to describe the genetic determinants of asthma in Cameroon and sub-Saharan Africa.
MeSH term(s)	Female ; Humans ; Aged ; Child ; Adolescent ; Young Adult ; Adult ; Male ; Case-Control Studies ; Cameroon ; Genetic Predisposition to Disease ; Polymorphism, Genetic ; Polymorphism, Restriction Fragment Length ; Genotype ; Polymorphism, Single Nucleotide ; Gene Frequency
Language	English
Publishing date	2023-04-12
Publishing country	Uganda
Document type	Journal Article
ZDB-ID	2514347-5
ISSN	1937-8688 ; 1937-8688
ISSN (online)	1937-8688
ISSN	1937-8688
DOI	10.11604/pamj.2023.44.166.38544
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Epidemiologie, aspects cliniques et therapeutiques du syndrome Coronarien chronique en milieu cardiologique camerounais : un regard sur 10 ans.

Mfeukeu-Kuate, Liliane / Hamadou, Ba / Nkeck, Jan René / Boombhi, Jerome / DipitaSosso, Albert / Menanga, Alain Patrick

Le Mali medical

2024 Volume 37, Issue 2, Page(s) 11–16

Abstract: Aim: The present study aims to describe the epidemiology, clinical and therapeutic aspects of chronic coronary syndrome (CCS) in Cameroonian cardiology setting in order to highlight the current state of practice to guide efficient epidemiological ... ...

Title translation	Epidemiology, clinical and therapeutic aspects of chronic coronary syndrome in Cameroonian cardiology, a look back at 10 years.
Abstract	Aim: The present study aims to describe the epidemiology, clinical and therapeutic aspects of chronic coronary syndrome (CCS) in Cameroonian cardiology setting in order to highlight the current state of practice to guide efficient epidemiological interventions. Method: We retrospectively analyzed over 10 years [2010; 2019] the records of patients hospitalized in two cardiology units of referral hospitals in the city of Yaoundé. Result: Of the 2756 records retrieved, 47 (1.7%) had CCS according to the 2019 European Society of Cardiology guidelines, with an average age of 58 ± 12 years, and 63.8% were men. The most common cardiovascular risk factors found were hypertension (78.7%), overweight or obesity (84.9%), dyslipidemias (80.9%), smoking (68.1%), and diabetes (67.7%). Chest pain on exertion (74.5%) and exertional dyspnea (70.2%) were the main symptoms. Repolarization disorders (83%) were the most frequent ECG signs; necrosis sequelae were found on ECG in 34% of cases and rhythm disorders in 21.3%. The therapeutic modalities were essentially anti-platelet (95.7%), statins (91.5%), beta blockers (89.4%), and converting enzyme blockers (70.2%). Interventional treatments were rarely performed (2.1%). Conclusion: Although chronic coronary syndrome are uncommon in cardiology hospitalization in Cameroon, it is essential that public health policies work to improve the current state of care particularly interventional care.
Language	French
Publishing date	2024-03-20
Publishing country	Mali
Document type	English Abstract ; Journal Article
ZDB-ID	2502651-3
ISSN	1993-0836 ; 1993-0836
ISSN (online)	1993-0836
ISSN	1993-0836
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Epidemiology of Digital Clubbing and Hypertrophic Osteoarthropathy: A Systematic Review and Meta-analysis.

Essouma, Mickael / Nkeck, Jan Réné / Agbor, Valirie N / Noubiap, Jean Jacques

Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases

2022 Volume 28, Issue 2, Page(s) 104–110

Abstract: Abstract: Digital clubbing and hypertrophic osteoarthropathy (HOA) are long-standing clinical entities, but their prevalence have not been synthesized. We aimed to estimate the prevalence of digital clubbing and HOA in people with existing medical ... ...

Abstract	Abstract: Digital clubbing and hypertrophic osteoarthropathy (HOA) are long-standing clinical entities, but their prevalence have not been synthesized. We aimed to estimate the prevalence of digital clubbing and HOA in people with existing medical conditions.We comprehensively searched PubMed, Embase, and Web of Science to select studies addressing HOA or digital clubbing and published through March 23, 2021. Summary estimates of the prevalence were derived through random-effects meta-analysis and narrative synthesis. The review protocol has been registered with PROSPERO, CRD42021243934.Of 3973 records, we included 142 studies. In adults, the pooled prevalence of digital clubbing was 33.4% (95% confidence interval [CI], 16.6-52.8), 31.3% (95% CI, 22.4-41.1), 27% (95% CI, 9.4-49.5), and 22.8% (95% CI, 10.8-37.6) in subjects with intestinal diseases, interstitial lung diseases, infective endocarditis, and hepatic diseases, respectively. In children and adolescents, the pooled prevalence of digital clubbing was 29.1% (95% CI, 19.4-39.9), 23% (95% CI, 9.0-41.1), 19.5% (95% CI, 4.1-42.4), and 17.1% (95% CI, 9.5-26.5) in subjects with human immunodeficiency virus infection, hemoglobinopathies, cystic fibrosis, and tuberculosis. The pooled prevalence of HOA was 10.1% (95% CI, 2.0-23.1) in adults with cancers, and 5% (95% CI, 2.5-8.2) in children and adolescents with cystic fibrosis.In conclusion, the prevalence of digital clubbing varied across disease groups in both adults and children. Full-spectrum HOA was mostly reported in adults with liver disease and cancers, and in children and adolescents with cystic fibrosis.
MeSH term(s)	Adolescent ; Adult ; Child ; Humans ; Lung Diseases, Interstitial ; Osteoarthropathy, Secondary Hypertrophic/diagnosis ; Osteoarthropathy, Secondary Hypertrophic/epidemiology ; Osteoarthropathy, Secondary Hypertrophic/etiology
Language	English
Publishing date	2022-01-19
Publishing country	United States
Document type	Journal Article ; Meta-Analysis ; Systematic Review
ZDB-ID	1283266-2
ISSN	1536-7355 ; 1076-1608
ISSN (online)	1536-7355
ISSN	1076-1608
DOI	10.1097/RHU.0000000000001830
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 4815: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (2.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: COVID 19 pandemic, status of clinical trials in Africa on May 2020: need to reinforce.

Nkeck, Jan René / Ndoadoumgue, Aude Laetitia / Temgoua, Mazou Ngou

The Pan African medical journal

2020 Volume 35, Issue Suppl 2, Page(s) 87

MeSH term(s)	Africa ; COVID-19/drug therapy ; COVID-19/physiopathology ; Clinical Trials as Topic/statistics & numerical data ; Drug Repositioning ; Humans
Language	English
Publishing date	2020-06-22
Publishing country	Uganda
Document type	Letter
ZDB-ID	2514347-5
ISSN	1937-8688 ; 1937-8688
ISSN (online)	1937-8688
ISSN	1937-8688
DOI	10.11604/pamj.supp.2020.35.2.24349
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: [No title information]

Nkeck, Jan René / Ondoa, Hélène-Ornella Bongha / Hamadjoda, Saquinatou / Essama, Doris Bibi / Talongong, Baudelaire Fojo / Ngandeu-Singwe, Madeleine

The Pan African medical journal

2023 Volume 46, Page(s) 1

Title translation	Développement d´un questionnaire d´évaluation des apports calciques journaliers chez le Camerounais (QUEVACC).
MeSH term(s)	Humans ; Calcium ; Cameroon ; Surveys and Questionnaires
Chemical Substances	Calcium (SY7Q814VUP)
Language	French
Publishing date	2023-09-01
Publishing country	Uganda
Document type	Journal Article
ZDB-ID	2514347-5
ISSN	1937-8688 ; 1937-8688
ISSN (online)	1937-8688
ISSN	1937-8688
DOI	10.11604/pamj.2023.46.1.41310
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Epidemiology of infective endocarditis in Africa: a systematic review and meta-analysis.

Noubiap, Jean Jacques / Nkeck, Jan René / Kwondom, Beckly Shu / Nyaga, Ulrich Flore

The Lancet. Global health

2021 Volume 10, Issue 1, Page(s) e77–e86

Abstract: ... published from inception to Jan 14, 2021, irrespective of the language. We used the search terms ...

Abstract	Background: The epidemiology of infective endocarditis in Africa is inadequately characterised. We therefore aimed to comprehensively summarise the available data for the incidence, risk factors, clinical pattern, microbiology, and outcomes of infective endocarditis in Africa. Methods: We did a systematic review and meta-analysis. We searched PubMed, Embase, African Index Medicus, and African Journals Online for all studies reporting primary data for the epidemiology of infective endocarditis in populations within Africa, published from inception to Jan 14, 2021, irrespective of the language. We used the search terms "endocarditis", "Africa", and the name of all African countries in the search strategy. We excluded articles that did not include primary data, primary studies with a small sample size (<30 participants), and those that report findings from before 1990. We recorded data for study characteristics, sample size, criteria used to define infective endocarditis, risk factors, potential entry site, clinical patterns, microbiology profile, outcomes including complications such as embolic events, heart failure, acute kidney injury, and death, and predictors of death. We used random-effects meta-analysis method to pool estimates. This study is registered with PROSPERO, CRD42021243842. Findings: We retrieved 2141 records from the database and bibliographic searches, of which a total of 42 studies were included in this systematic review. Rheumatic heart disease was the most common risk factor for infective endocarditis in adults (52·0% [95% CI 42·4-61·5]), whereas congenital heart disease was the most common risk factor for infective endocarditis in children (44·7% [29·5-60·5]). Microbiological testing (mostly blood cultures) was positive in 48·6% (95% CI 42·2-51·1) of patients with infective endocarditis, with Staphylococcus species (41·3% [95% CI 36·2-46·5]) and Streptococcus species (34·0% [29·0-39·3]) the most commonly identified microorganisms. The pooled rate of surgical treatment of infective endocarditis was 49·1% (95% CI 43·2-55·1). The pooled in-hospital mortality rate was 22·6% (95% CI 19·5-25·9). Other frequent complications included heart failure (47·0% [95% CI 38·2-56·0]), acute kidney injury (22·8% [18·8-27·0]), and embolic events (31·1% [22·2-40·7]). Interpretation: As the most prevalent risk factor in Africa, rheumatic heart disease should be central in interventions to reduce the burden of infective endocarditis on the continent. In tertiary hospitals with good access to cardiac surgery, the outcomes of infective endocarditis seem relatively similar to what has been reported in other parts of the world, especially in high-income countries. Funding: None.
MeSH term(s)	Africa/epidemiology ; Comorbidity ; Endocarditis/epidemiology ; Endocarditis/etiology ; Humans ; Incidence ; Rheumatic Heart Disease/complications ; Risk Factors ; Sociodemographic Factors
Language	English
Publishing date	2021-12-10
Publishing country	England
Document type	Journal Article ; Meta-Analysis ; Systematic Review
ZDB-ID	2723488-5
ISSN	2214-109X ; 2214-109X
ISSN (online)	2214-109X
ISSN	2214-109X
DOI	10.1016/S2214-109X(21)00400-9
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: An alert on the incautious use of herbal medicines by sub-Saharan African populations to fight against the COVID-19.

Nkeck, Jan René / Tsafack, Edmond Elisée / Ndoadoumgue, Aude Laetitia / Endomba, Francky Teddy

The Pan African medical journal

2020 Volume 35, Issue Suppl 2, Page(s) 26

MeSH term(s)	Africa South of the Sahara ; COVID-19/drug therapy ; Humans ; Medicine, African Traditional/adverse effects ; Medicine, African Traditional/methods ; Phytotherapy/adverse effects ; Phytotherapy/methods ; Plant Preparations/administration & dosage ; Plant Preparations/adverse effects ; Plants, Medicinal/chemistry
Chemical Substances	Plant Preparations
Language	English
Publishing date	2020-05-07
Publishing country	Uganda
Document type	Letter
ZDB-ID	2514347-5
ISSN	1937-8688 ; 1937-8688
ISSN (online)	1937-8688
ISSN	1937-8688
DOI	10.11604/pamj.supp.2020.35.2.23161
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Leptin and psychiatric illnesses: does leptin play a role in antipsychotic-induced weight gain?

Endomba, Francky Teddy / Tankeu, Aurel T / Nkeck, Jan René / Tochie, Joel Noutakdie

Lipids in health and disease

2020 Volume 19, Issue 1, Page(s) 22

Abstract: Antipsychotic-induced weight gain is the most prevalent somatic adverse event occurring in patients treated by antipsychotics, especially atypical antipsychotics. It is of particular interest because of its repercussion on cardiovascular morbidity and ... ...

Abstract	Antipsychotic-induced weight gain is the most prevalent somatic adverse event occurring in patients treated by antipsychotics, especially atypical antipsychotics. It is of particular interest because of its repercussion on cardiovascular morbidity and mortality especially now that the use of second-generation antipsychotics has been extended to other mental health illnesses such as bipolar disorders and major depressive disorder. The mechanism underlying antipsychotics-induced weight gain is still poorly understood despite a significant amount of work on the topic. Recently, there has been an on-going debate of tremendous research interest on the relationship between antipsychotic-induced weight gain and body weight regulatory hormones such as leptin. Given that, researchers have brought to light the question of leptin's role in antipsychotic-induced weight gain. Here we summarize and discuss the existing evidence on the link between leptin and weight gain related to antipsychotic drugs, especially atypical antipsychotics.
MeSH term(s)	Antipsychotic Agents/adverse effects ; Antipsychotic Agents/therapeutic use ; Depressive Disorder, Major/drug therapy ; Female ; Humans ; Leptin/metabolism ; Male ; Weight Gain/drug effects
Chemical Substances	Antipsychotic Agents ; Leptin
Language	English
Publishing date	2020-02-07
Publishing country	England
Document type	Journal Article ; Review
ISSN	1476-511X
ISSN (online)	1476-511X
DOI	10.1186/s12944-020-01203-z
Database	MEDical Literature Analysis and Retrieval System OnLINE

Full text online

Accessible to users with ZB MED library card

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Details ▾
- Full text online
- Order with fees

To top

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito

Inter-library loan at ZB MED

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito

Full text online

More links

Kategorien

Order via subito

Inter-library loan at ZB MED