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  1. Article ; Online: A

    Abu Shtaya, Aasem / Kedar, Inbal / Bazak, Lily / Basel-Salmon, Lina / Barhom, Sarit Farage / Naftali, Michal / Eskin-Schwartz, Marina / Birk, Ohad S / Polager-Modan, Shirley / Keidar, Nitzan / Reznick Levi, Gili / Levi, Zohar / Yablonski-Peretz, Tamar / Mahamid, Ahmad / Segol, Ori / Matar, Reut / Bareli, Yifat / Azoulay, Noy / Goldberg, Yael

    Genes

    2024  Volume 15, Issue 3

    Abstract: POT1 (Protection of Telomeres 1) is a key component of the six-membered shelterin complex that plays a critical role in telomere protection and length regulation. Germline variants in ... ...

    Abstract POT1 (Protection of Telomeres 1) is a key component of the six-membered shelterin complex that plays a critical role in telomere protection and length regulation. Germline variants in the
    MeSH term(s) Male ; Humans ; Female ; Adult ; Middle Aged ; Aged ; Melanoma/genetics ; Leukemia, Lymphocytic, Chronic, B-Cell/genetics ; Telomere-Binding Proteins/genetics ; Skin Neoplasms/genetics ; Thyroid Neoplasms ; Shelterin Complex
    Chemical Substances Telomere-Binding Proteins ; POT1 protein, human ; Shelterin Complex
    Language English
    Publishing date 2024-03-13
    Publishing country Switzerland
    Document type Review ; Journal Article
    ZDB-ID 2527218-4
    ISSN 2073-4425 ; 2073-4425
    ISSN (online) 2073-4425
    ISSN 2073-4425
    DOI 10.3390/genes15030355
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: A

    Haq, Anwar Ul / Ahmad, Tasawer Shahzad / Ahmad, Afaq / Almutairi, Badriah S / Amin, Muhammad / Khan, M I / Ehsan, Nimra / Sharma, Ramesh

    Heliyon

    2023  Volume 9, Issue 11, Page(s) e21702

    Abstract: Recently, all inorganic double perovskites have drawn a lot of interest as promising solar materials. The optical, structural, thermoelectric, electronic, and mechanical properties of double halide perovskites ... ...

    Abstract Recently, all inorganic double perovskites have drawn a lot of interest as promising solar materials. The optical, structural, thermoelectric, electronic, and mechanical properties of double halide perovskites A
    Language English
    Publishing date 2023-10-30
    Publishing country England
    Document type Journal Article
    ZDB-ID 2835763-2
    ISSN 2405-8440
    ISSN 2405-8440
    DOI 10.1016/j.heliyon.2023.e21702
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: A

    Bajpai, Anjali / Quazi, Taushif Ahmad / Tang, Hong-Wen / Manzar, Nishat / Singh, Virender / Thakur, Ashwani / Ateeq, Bushra / Perrimon, Norbert / Sinha, Pradip

    Disease models & mechanisms

    2020  Volume 13, Issue 7

    Abstract: Peptide therapeutics, unlike small-molecule drugs, display crucial advantages of target specificity and the ability to block large interacting interfaces, such as those of transcription factors. The transcription co-factor of the Hippo pathway, YAP/ ... ...

    Abstract Peptide therapeutics, unlike small-molecule drugs, display crucial advantages of target specificity and the ability to block large interacting interfaces, such as those of transcription factors. The transcription co-factor of the Hippo pathway, YAP/Yorkie (Yki), has been implicated in many cancers, and is dependent on its interaction with the DNA-binding TEAD/Sd proteins via a large Ω-loop. In addition, the mammalian vestigial-like (VGLL) proteins, specifically their TONDU domain, competitively inhibit YAP-TEAD interaction, resulting in arrest of tumor growth. Here, we show that overexpression of the TONDU peptide or its oral uptake leads to suppression of Yki-driven intestinal stem cell tumors in the adult
    MeSH term(s) Administration, Oral ; Animals ; Animals, Genetically Modified ; Antineoplastic Agents/administration & dosage ; Antineoplastic Agents/metabolism ; Cell Proliferation/drug effects ; DNA-Binding Proteins/administration & dosage ; DNA-Binding Proteins/genetics ; DNA-Binding Proteins/metabolism ; Disease Models, Animal ; Drosophila Proteins/genetics ; Drosophila Proteins/metabolism ; Drosophila melanogaster/drug effects ; Drosophila melanogaster/genetics ; Drosophila melanogaster/metabolism ; Drug Development ; Drug Screening Assays, Antitumor ; Female ; Gene Expression Regulation, Neoplastic ; Humans ; Intestinal Neoplasms/drug therapy ; Intestinal Neoplasms/genetics ; Intestinal Neoplasms/metabolism ; Intestinal Neoplasms/pathology ; Neoplastic Stem Cells/drug effects ; Neoplastic Stem Cells/metabolism ; Neoplastic Stem Cells/pathology ; Nuclear Proteins/genetics ; Nuclear Proteins/metabolism ; PC-3 Cells ; Peptide Fragments/administration & dosage ; Peptide Fragments/genetics ; Peptide Fragments/metabolism ; Signal Transduction ; Trans-Activators/genetics ; Trans-Activators/metabolism ; Transcription Factors/administration & dosage ; Transcription Factors/genetics ; Transcription Factors/metabolism ; YAP-Signaling Proteins
    Chemical Substances Antineoplastic Agents ; DNA-Binding Proteins ; Drosophila Proteins ; Nuclear Proteins ; Peptide Fragments ; Trans-Activators ; Transcription Factors ; VGLL1 protein, human ; YAP-Signaling Proteins ; Yki protein, Drosophila ; esg protein, Drosophila ; sd protein, Drosophila
    Language English
    Publishing date 2020-07-23
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2451104-3
    ISSN 1754-8411 ; 1754-8403
    ISSN (online) 1754-8411
    ISSN 1754-8403
    DOI 10.1242/dmm.044420
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: A

    Marin-Mogollon, Catherin / Salman, Ahmed M / Koolen, Karin M J / Bolscher, Judith M / van Pul, Fiona J A / Miyazaki, Shinya / Imai, Takashi / Othman, Ahmad Syibli / Ramesar, Jai / van Gemert, Geert-Jan / Kroeze, Hans / Chevalley-Maurel, Severine / Franke-Fayard, Blandine / Sauerwein, Robert W / Hill, Adrian V S / Dechering, Koen J / Janse, Chris J / Khan, Shahid M

    Frontiers in cellular and infection microbiology

    2019  Volume 9, Page(s) 96

    Abstract: Transgenic malaria parasites expressing fluorescent and bioluminescent proteins are valuable tools to interrogate malaria-parasite biology and to evaluate drugs and vaccines. Using CRISPR/Cas9 methodology a ... ...

    Abstract Transgenic malaria parasites expressing fluorescent and bioluminescent proteins are valuable tools to interrogate malaria-parasite biology and to evaluate drugs and vaccines. Using CRISPR/Cas9 methodology a transgenic
    MeSH term(s) Animals ; Artificial Gene Fusion ; CRISPR-Associated Protein 9/metabolism ; Clustered Regularly Interspaced Short Palindromic Repeats ; Erythrocytes ; Gene Editing ; Gene Expression Profiling ; Genes, Reporter ; Humans ; Liver/parasitology ; Luciferases/analysis ; Luciferases/genetics ; Mice, SCID ; Plasmodium falciparum/genetics ; Plasmodium falciparum/growth & development ; Recombinant Proteins/analysis ; Recombinant Proteins/genetics ; Sporozoites/genetics ; Sporozoites/growth & development ; Staining and Labeling/methods
    Chemical Substances Recombinant Proteins ; Luciferases (EC 1.13.12.-) ; CRISPR-Associated Protein 9 (EC 3.1.-)
    Language English
    Publishing date 2019-04-16
    Publishing country Switzerland
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2619676-1
    ISSN 2235-2988 ; 2235-2988
    ISSN (online) 2235-2988
    ISSN 2235-2988
    DOI 10.3389/fcimb.2019.00096
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: A

    Khan, Jehangir / Adil, Muhammad / Wang, Gang / Tsheten, Tsheten / Zhang, Dongjing / Pan, Wenjie / Khan, Munir Ahmad / Rehman, Inayat Ur / Zheng, Xiaoying / Wu, Zhongdao / Wu, Yu

    Frontiers in public health

    2022  Volume 10, Page(s) 923277

    Abstract: Background: Dengue fever has been responsible for around 12 countrywide large outbreaks in Pakistan, resulting in 286,262 morbidities and 1,108 deaths. Khyber Pakhtunkhwa (KP) is the most recently impacted province. This study aimed to investigate the ... ...

    Abstract Background: Dengue fever has been responsible for around 12 countrywide large outbreaks in Pakistan, resulting in 286,262 morbidities and 1,108 deaths. Khyber Pakhtunkhwa (KP) is the most recently impacted province. This study aimed to investigate the molecular, epidemiological, and potential elements that contribute to increasing dengue transmission patterns, and knowledge, attitude, and practice (KAP) toward dengue in KP province.
    Method: This cross-sectional community-based study was conducted (June-December, 2021) in two phases. Phase I involved the epidemiological (
    Results: Peshawar district had the highest dengue cases (60.0%) associated with the predominant co-circulation of DENV-2 (45.8%) and DENV-3 (50.4%) serotypes. A rise in cases was reported in October (41.8%) followed by September (27.9%) and August (14.4%;
    Conclusion: Multiple poor socioeconomic elements are influencing dengue fever transmission in the province. Higher KAP levels may explain the low frequency of dengue in non-hotspot districts. Our study emphasizes the need for effective and long-term public health education, strengthened vector surveillance, and expanded laboratory capacity for better diagnosis and management of dengue cases to better predict the burden and seasonality of disease in the country.
    MeSH term(s) Cross-Sectional Studies ; Dengue/diagnosis ; Dengue/epidemiology ; Dengue/prevention & control ; Health Knowledge, Attitudes, Practice ; Humans ; Male ; Pakistan/epidemiology ; Risk Factors
    Language English
    Publishing date 2022-07-29
    Publishing country Switzerland
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2711781-9
    ISSN 2296-2565 ; 2296-2565
    ISSN (online) 2296-2565
    ISSN 2296-2565
    DOI 10.3389/fpubh.2022.923277
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: A

    Kabir-Ud-Din / Fatma, Waseefa / Khan, Ziya Ahmad

    Colloid and polymer science

    2006  Volume 284, Page(s) 1339–1344

    Abstract: The effect of addition of sodium anthranilate to 5 mM micellar solutions of gemini surfactant 1,4-bis( ...

    Abstract The effect of addition of sodium anthranilate to 5 mM micellar solutions of gemini surfactant 1,4-bis(
    Language English
    Publishing date 2006-04-08
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 124984-8
    ISSN 0303-402X ; 0023-2904
    ISSN 0303-402X ; 0023-2904
    DOI 10.1007/s00396-005-1417-z
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    In stock of ZB MED Bonn / Germany

    Z 4' 55/12: Show issues

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  7. Book: Clinical trials in surgical oncology

    Ahmad, Syed A.

    (Surgical oncology clinics of North America ; volume 32, number 1 (January 2023))

    2023  

    Author's details editors Syed A. Ahmad, Shishir K. Maithel
    Series title Surgical oncology clinics of North America ; volume 32, number 1 (January 2023)
    Collection
    Language English
    Size xvi, 232 Seiten, Illustrationen
    Publisher Elsevier
    Publishing place Philadelphia, Pennsylvania
    Publishing country United States
    Document type Book
    HBZ-ID HT021716233
    ISBN 978-0-323-96083-0 ; 0-323-96083-9
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    Se 1339 -32,1- not available for loan Lesesaal EG

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  8. Book ; Thesis: Relationship between implant geometry and primary stability in different bony defects and variant bone densities: an in vitro study

    Ibrahim, Ahmad

    2023  

    Author's details vorgelegt von Ahmad Khaled Ahmad Ali Ibrahim
    Language English
    Size 16 Seiten, Illustrationen
    Publishing place Aachen
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Dissertation, Rheinisch-Westfälische Technische Hochschule Aachen, 2023
    Note Die Dissertation besteht aus einem Aufsatz, der zuvor in der Zeitschrift "Materials" (2020, 13, 4349) veröffentlicht wurde; DOI: 10.3390/ma13194349
    HBZ-ID HT030628102
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2024 D 37 order for loan Magazin

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  9. Book ; Audio / Video ; Thesis: Monocentric cohort study of patients with SARS-CoV2/COVID-19 infection at the intermediate and intensive care units

    Alkhatib, Ahmad

    2022  

    Author's details submitted by Ahmad Alkhatib
    Language English
    Size 1 CD-ROM
    Publishing place Witten/Herdecke
    Publishing country Germany
    Document type Book ; Audio / Video ; Thesis
    Thesis / German Habilitation thesis Dissertation, Universität Witten/Herdecke, 2022
    HBZ-ID HT030020753
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2023 MO 40 order for loan Magazin

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  10. Book ; Online ; E-Book: Advanced Nondestructive and Structural Techniques for Diagnosis, Redesign and Health Monitoring for the Preservation of Cultural Heritage

    Osman, Ahmad / Moropoulou, A.

    Selected work from the TMM-CH 2021

    (Springer Proceedings in Materials, ; 16)

    2022  

    Abstract: Based on the success of the first published book on “Nondestructive Evaluation and Monitoring Technologies, Documentation, Diagnosis and Preservation of Cultural Heritage”, this book will includes peer reviewed papers submitted to the conference in form ... ...

    Author's details edited by Ahmad Osman, Antonia Moropoulou
    Series title Springer Proceedings in Materials, ; 16
    Abstract Based on the success of the first published book on “Nondestructive Evaluation and Monitoring Technologies, Documentation, Diagnosis and Preservation of Cultural Heritage”, this book will includes peer reviewed papers submitted to the conference in form of single independent chapters. Each chapter will highlight the benefits of one or more Non-Destructive Testing (NDT) methods, image processing and data analysis methods and their applications on cultural heritage sites. This book demonstrates Non-destructive sensing technologies and inspection modules as main tools for documentation, diagnosis, characterization, preservation planning, monitoring and quality of restoration, assessment and evaluation of material and preservation work. Within this book, the benefits of NDT methods and their applications will be demonstrated on diverse and important cultural heritage sites and monuments around the world. NDT sensing technologies and inspection modules are becoming main tools for the documentation, diagnosis, characterization, preservation planning, monitoring and quality control of restoration, assessment and evaluation of materials and preservation works. Distinguished scientists and representatives of the National Geographic Society, the Cultural Heritage Finance Alliance, the International Council of Monuments and Sites ICOMOS, the Organization of World Heritage Cities OWHC, the European Society for Engineering Education SEFI, the European Construction Technology Platform ECTP, the International Federation of Surveyors FIG, the International Committee CIPA Heritage Documentation, the World Monuments Fund and other major International and European Organizations, Associations, networks Universities and Research Centers in the field of cultural heritage preservation, participate in to the International Steering Committee which had successfully organized the 1st TMM_CH Conference as well. .
    Keywords Materials/Analysis ; Cultural property ; Materials Characterization Technique ; Cultural Heritage
    Subject code 363.69
    Language English
    Size 1 online resource (215 pages)
    Edition 1st ed. 2022.
    Publisher Springer International Publishing ; Imprint: Springer
    Publishing place Cham
    Document type Book ; Online ; E-Book
    Note Description based upon print version of record.
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    ISBN 3-031-03795-2 ; 9783031037948 ; 978-3-031-03795-5 ; 3031037944
    DOI 10.1007/978-3-031-03795-5
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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