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  1. Article ; Online: An automatic approach based on CNN architecture to detect Covid-19 disease from chest X-ray images.

    Hira, Swati / Bai, Anita / Hira, Sanchit

    Applied intelligence (Dordrecht, Netherlands)

    2020  Volume 51, Issue 5, Page(s) 2864–2889

    Abstract: Novel coronavirus (COVID-19) is started from Wuhan (City in China), and is rapidly spreading among people living in other countries. Today, around 215 countries are affected by COVID-19 disease. WHO announced approximately number of cases 11,274,600 ... ...

    Abstract Novel coronavirus (COVID-19) is started from Wuhan (City in China), and is rapidly spreading among people living in other countries. Today, around 215 countries are affected by COVID-19 disease. WHO announced approximately number of cases 11,274,600 worldwide. Due to rapidly rising cases daily in the hospitals, there are a limited number of resources available to control COVID-19 disease. Therefore, it is essential to develop an accurate diagnosis of COVID-19 disease. Early diagnosis of COVID-19 patients is important for preventing the disease from spreading to others. In this paper, we proposed a deep learning based approach that can differentiate COVID- 19 disease patients from viral pneumonia, bacterial pneumonia, and healthy (normal) cases. In this approach, deep transfer learning is adopted. We used binary and multi-class dataset which is categorized in four types for experimentation: (i) Collection of 728 X-ray images including 224 images with confirmed COVID-19 disease and 504 normal condition images (ii) Collection of 1428 X-ray images including 224 images with confirmed COVID-19 disease, 700 images with confirmed common bacterial pneumonia, and 504 normal condition images. (iii) Collections of 1442 X- ray images including 224 images with confirmed COVID-19 disease, 714 images with confirmed bacterial and viral pneumonia, and 504 images of normal conditions (iv) Collections of 5232 X- ray images including 2358 images with confirmed bacterial and 1345 with viral pneumonia, and 1346 images of normal conditions. In this paper, we have used nine convolutional neural network based architecture (AlexNet, GoogleNet, ResNet-50, Se-ResNet-50, DenseNet121, Inception V4, Inception ResNet V2, ResNeXt-50, and Se-ResNeXt-50). Experimental results indicate that the pre trained model Se-ResNeXt-50 achieves the highest classification accuracy of 99.32% for binary class and 97.55% for multi-class among all pre-trained models.
    Language English
    Publishing date 2020-11-27
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 1479519-X
    ISSN 1573-7497 ; 0924-669X
    ISSN (online) 1573-7497
    ISSN 0924-669X
    DOI 10.1007/s10489-020-02010-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Intentional Replantation Of Mandibular First Molar With Two Years Follow Up- Case Report.

    Javed, Muhammad Qasim / Zaman, Hira / Srivastava, Swati / Khan, Zohra Jabeen

    Journal of Ayub Medical College, Abbottabad : JAMC

    2022  Volume 34, Issue 3, Page(s) 569–572

    Abstract: Background: Intentional replantation (IR) is a reliable and predictable treatment option for cases with failed non-surgical root canal treatment. The success of IR is found to be 52-95%. The current case is of 35years old female who presented with ... ...

    Abstract Background: Intentional replantation (IR) is a reliable and predictable treatment option for cases with failed non-surgical root canal treatment. The success of IR is found to be 52-95%. The current case is of 35years old female who presented with severe pain and swelling in lower right first mandibular molar with previously initiated non-surgical root canal treatment that resulted in instrument separation in mesio-buccal canal. Periapical radiograph showed rarefactions at furcation area, mesial and distal root apices. It was decided to complete the non-surgical root canal treatment followed by intentional replantation and retrograde filling with MTA. The tooth was found to be asymptomatic after two years follow up and periapical radiographs depicted complete healing. Intentional replantation with careful case selection is a successful, easy and reliable treatment option for hopeless cases. Atraumatic extraction, minimum extra-alveolar time and aseptic techniques during the procedure are the key factors for success of the procedure.
    MeSH term(s) Humans ; Female ; Tooth Replantation ; Follow-Up Studies ; Molar/surgery ; Root Canal Therapy ; Tooth Root
    Language English
    Publishing date 2022-11-15
    Publishing country Pakistan
    Document type Case Reports
    ZDB-ID 2192473-9
    ISSN 1819-2718 ; 1025-9589
    ISSN (online) 1819-2718
    ISSN 1025-9589
    DOI 10.55519/JAMC-03-9754
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Mining precise cause and effect rules in large time series data of socio-economic indicators.

    Hira, Swati / Deshpande, P S

    SpringerPlus

    2016  Volume 5, Issue 1, Page(s) 1625

    Abstract: Discovery of cause-effect relationships, particularly in large databases of time-series is challenging because of continuous data of different characteristics and complex lagged relationships. In this paper, we have proposed a novel approach, to extract ... ...

    Abstract Discovery of cause-effect relationships, particularly in large databases of time-series is challenging because of continuous data of different characteristics and complex lagged relationships. In this paper, we have proposed a novel approach, to extract cause-effect relationships in large time series data set of socioeconomic indicators. The method enhances the scope of relationship discovery to cause-effect relationships by identifying multiple causal structures such as binary, transitive, many to one and cyclic. We use temporal association and temporal odds ratio to exclude noncausal association and to ensure the high reliability of discovered causal rules. We assess the method with both synthetic and real-world datasets. Our proposed method will help to build quantitative models to analyze socioeconomic processes by generating a precise cause-effect relationship between different economic indicators. The outcome shows that the proposed method can effectively discover existing causality structure in large time series databases.
    Language English
    Publishing date 2016-09-21
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2661116-8
    ISSN 2193-1801
    ISSN 2193-1801
    DOI 10.1186/s40064-016-3292-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Dual-phase computed tomography for localization of parathyroid lesions in children and adolescents with primary hyperparathyroidism.

    Sharma, Anima / Patil, Virendra / Sarathi, Vijaya / Purandare, Nilendu / Hira, Priya / Memon, Saba / Jadhav, Swati S / Karlekar, Manjiri / Lila, Anurag R / Bandgar, Tushar

    Annales d'endocrinologie

    2023  Volume 84, Issue 4, Page(s) 446–453

    Abstract: Background: Childhood and adolescent primary hyperparathyroidism (PHPT) is a rare disease caused by single adenomas in 65-94% of patients. In this patient group, there is no data on computed tomography (CT) for pre-operative parathyroid localization ... ...

    Abstract Background: Childhood and adolescent primary hyperparathyroidism (PHPT) is a rare disease caused by single adenomas in 65-94% of patients. In this patient group, there is no data on computed tomography (CT) for pre-operative parathyroid localization that may facilitate focused parathyroidectomy.
    Methods: Two radiologists reviewed dual-phase (nonenhanced and arterial) CT images of twenty-three operated children and adolescents [20:single-gland disease(SGD), 3:multi-glandular disease(MGD)] with proven histopathological PHPT. Percentage arterial enhancement (PAE) was calculated as [100*{arterial-phase Hounsfield unit (HU)-nonenhanced phase HU}/nonenhanced HU] of the parathyroid lesion(s), thyroid, and lymph node.
    Results: Dual-phase CT lateralized 100%, localized to the correct quadrant/site 85% SGD (including 3/3 ectopic), and identified 1/3 MGD. PAE (cutoff ≥ 112.3%) was sensitive (91.3%) and specific (99.5%) in distinguishing parathyroid lesions from local mimics (P<0.001). The average effective dose was 3.16±1.01mSv, comparable to the planar/single photon emission CT (SPECT) Technetium 99m(Tc)-sestamibi and choline positron emission tomography (PET)/CT scans. Solid-cystic morphology identified in 4 patients harboring pathogenic germline variants (3:CDC73, 1:CASR) may serve as a radiological clue to molecular diagnosis. Nineteen out of 20 (95%) patients with SGD who had undergone single gland resection based on pre-operative CT findings were in remission over a median follow-up of 18 months.
    Conclusion: As most children/adolescents with PHPT have SGD, dual-phase CT protocols which reduce the effective radiation dose with high localization sensitivity for single parathyroid lesions may be a sustainable pre-operative imaging modality in this patient group.
    MeSH term(s) Humans ; Adolescent ; Child ; Hyperparathyroidism, Primary/diagnostic imaging ; Hyperparathyroidism, Primary/surgery ; Technetium Tc 99m Sestamibi ; Parathyroid Glands/diagnostic imaging ; Parathyroid Glands/surgery ; Tomography, X-Ray Computed ; Tomography, Emission-Computed, Single-Photon/methods ; Radiopharmaceuticals ; Positron Emission Tomography Computed Tomography/methods
    Chemical Substances Technetium Tc 99m Sestamibi (971Z4W1S09) ; Radiopharmaceuticals
    Language English
    Publishing date 2023-03-10
    Publishing country France
    Document type Journal Article
    ZDB-ID 299-9
    ISSN 2213-3941 ; 0003-4266
    ISSN (online) 2213-3941
    ISSN 0003-4266
    DOI 10.1016/j.ando.2023.03.001
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: A Novel Grading System for Salpingopharyngeal Fold Hypertrophy in Obstructive Sleep Apnoea.

    Agrawal, Vikas K / Kodur, Swati / Jha, Raghav Hira

    Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India

    2018  Volume 71, Issue 1, Page(s) 60–65

    Abstract: The present study aimed at reporting the incidence of Salpingopharyngeal Fold (SPF) hypertrophy on Drug Induced Sleep Endoscopy (DISE) in patients with Obstructive Sleep Apnoea (OSA, validate a grading system and analyse the impact of various grades on ... ...

    Abstract The present study aimed at reporting the incidence of Salpingopharyngeal Fold (SPF) hypertrophy on Drug Induced Sleep Endoscopy (DISE) in patients with Obstructive Sleep Apnoea (OSA, validate a grading system and analyse the impact of various grades on the clinical presentation while ascertaining its relation with Apnoea-Hypopnoea Index (AHI). A retrospective analysis of 169 patients with polysomnographic confirmation of obstructive sleep apnoea has been done in the study. The DISE video data of 169 patients was evaluated by two ENT surgeons individually and they graded the hypertrophy of the fold as Grade 0 being normal anatomy, Grade 1 being hypertrophy causing partial obstruction and Grade 2 being hypertrophy causing complete obstruction of lateral pharyngeal wall. It was found that the presence of SPF hypertrophy independently adds considerably to the severity of the obstruction, attributing to lateral collapse at the upper retropalatal level and also significantly increases AHI. It is thus advised to consider the grade of SPF hypertrophy while surgically planning the management of patients with OSA.
    Language English
    Publishing date 2018-10-16
    Publishing country India
    Document type Journal Article
    ZDB-ID 1471137-0
    ISSN 0973-7707 ; 2231-3796 ; 0019-5421
    ISSN (online) 0973-7707
    ISSN 2231-3796 ; 0019-5421
    DOI 10.1007/s12070-018-1513-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Recurrence Based Similarity Identification of Climate Data

    Anita Bai / Swati Hira / S. Deshpande Parag

    Discrete Dynamics in Nature and Society, Vol

    2017  Volume 2017

    Abstract: Climate change has become a challenging and emerging research problem in many research related areas. One of the key parameters in analyzing climate change is to analyze temperature variations in different regions. The temperature variation in a region ... ...

    Abstract Climate change has become a challenging and emerging research problem in many research related areas. One of the key parameters in analyzing climate change is to analyze temperature variations in different regions. The temperature variation in a region is periodic within the interval. Temperature variations, though periodic in nature, may vary from one region to another and such variations are mainly dependent on the location and altitude of the region and also on other factors like the nearness of sea and vegetation. In this paper, we analyze such periodic variations using recurrence plot (RP), cross recurrence plot (CRP), recurrence rate (RR), and correlation of probability of recurrence (CPR) methods to find similarities of periodic variations between and within climatic regions and to identify their connectivity trend. First, we test the correctness of our method by applying it on voice and heart rate data and then experimentation is performed on synthetic climate data of nine regions in the United States and eight regions in China. Finally, the accuracy of our approach is validated on both real and synthetic datasets and demonstrated using ANOVA, Kruskal–Wallis, and z-statistics significance tests.
    Keywords Mathematics ; QA1-939 ; Social sciences (General) ; H1-99
    Subject code 333
    Language English
    Publishing date 2017-01-01T00:00:00Z
    Publisher Hindawi Publishing Corporation
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article ; Online: Percentage arterial enhancement on 2D CT in the diagnosis of primary hyperparathyroidism: A prospective validation study and potential pitfalls.

    Sonawane, Sushil / Jadhav, Swati S / Goroshi, Manjunath / Krishnappa, Brijesh / Sharma, Anima / Hira, Priya / Garle, Mahadev N / Gosavi, Vikrant / Memon, Saba / Patil, Virendra A / Lila, Anurag R / Shah, Nalini / Bandgar, Tushar

    Head & neck

    2022  Volume 44, Issue 8, Page(s) 1849–1856

    Abstract: Background: Parathyroid lesions are identified by subjective enhancement and washout patterns on computed tomography (CT). We have previously proposed "percentage arterial enhancement" (PAE) as an objective index and now aim to validate its performance ... ...

    Abstract Background: Parathyroid lesions are identified by subjective enhancement and washout patterns on computed tomography (CT). We have previously proposed "percentage arterial enhancement" (PAE) as an objective index and now aim to validate its performance prospectively.
    Methods: Dual-phase CT was performed in 40 consecutive primary hyperparathyroidism patients. PAE was calculated as [{arterial phase Hounsfield unit (HU)-unenhanced phase HU}/unenhanced phase HU] × 100. PAE > 128.9% was considered parathyroid.
    Results: PAE had 94.2% sensitivity, 100% positive predictive value (PPV) in lateralization, and sensitivity and PPV of 93.9% in quadrant localization of single-gland disease. PAE failed to identify two lesions: an intrathyroidal parathyroid carcinoma in the background of multinodular goiter and another lower enhancing cystic parathyroid adenoma. PAE had 60% sensitivity, and 100% PPV to identify multigland disease. The mean effective dose was 2.74 mSV.
    Conclusions: PAE is a specific CT index for parathyroid lesions with less radiation exposure. Areas of caution include intrathyroidal and cystic lesions.
    MeSH term(s) Adenoma/pathology ; Humans ; Hyperparathyroidism, Primary/diagnostic imaging ; Hyperparathyroidism, Primary/pathology ; Parathyroid Glands/pathology ; Parathyroid Neoplasms/diagnostic imaging ; Parathyroid Neoplasms/pathology ; Sensitivity and Specificity ; Tomography, X-Ray Computed/methods
    Language English
    Publishing date 2022-05-31
    Publishing country United States
    Document type Journal Article
    ZDB-ID 645165-2
    ISSN 1097-0347 ; 0148-6403 ; 1043-3074
    ISSN (online) 1097-0347
    ISSN 0148-6403 ; 1043-3074
    DOI 10.1002/hed.27108
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Genotype-Phenotype Correlations in Asian Indian Children and Adolescents with Primary Hyperparathyroidism.

    Sharma, Anima / Memon, Saba / Lila, Anurag R / Sarathi, Vijaya / Arya, Sneha / Jadhav, Swati S / Hira, Priya / Garale, Mahadeo / Gosavi, Vikrant / Karlekar, Manjiri / Patil, Virendra / Bandgar, Tushar

    Calcified tissue international

    2022  Volume 111, Issue 3, Page(s) 229–241

    Abstract: Childhood and adolescent primary hyperparathyroidism (PHPT) is a very rare disease. Data on its molecular genetics are scarce. We performed a retrospective analysis (January 2000-January 2021) to determine the deleterious germline variants and genotype- ... ...

    Abstract Childhood and adolescent primary hyperparathyroidism (PHPT) is a very rare disease. Data on its molecular genetics are scarce. We performed a retrospective analysis (January 2000-January 2021) to determine the deleterious germline variants and genotype-phenotype correlations in children and adolescents < 20 years diagnosed with PHPT from a single referral center. Clinical features, biochemistry, imaging, management, and genetics (clinical exome analyzed for 11 PHPT and 7 pancreatitis-associated genes, MLPA for CDC73) were recorded. Thirty-six patients (20 males; median age 17 years) were classified into those with familial and/or syndromic (F/S) or apparently sporadic (AS) presentation. Sixteen (44.4%) harbored pathogenic/likely pathogenic germline variants in PHPT-associated genes. The genetic yield in F/S group was 90% (MEN1:8/10; CDC73:1/10), and AS group was 26.9% (CDC73:4/26; CASR:3/26). F/S group had frequent asymptomatic presentation (60% vs none; P < 0.001), lower serum PTH (237.5 vs 1369.1 pg/mL; P = 0.001), and maximum parathyroid dimension (0.9 vs 2.2 cm; P = 0.01) than AS group. Among the AS group, renal involvement was higher in those with molecular diagnoses (71.4% vs 10.5%; P = 0.01). All those with novel CASR variants (including one homozygous) had hypercalciuria and histology-proven parathyroid adenoma/carcinoma. A missense CTRC VUS occurred in one patient with chronic pancreatitis. In summary, Asian Indian children and adolescents with PHPT have high genetic yield, even with apparently sporadic presentation. The phenotypic spectrum of CASR variants is expanded to include childhood/adolescent PHPT with hypercalciuria and single gland neoplasia. The proposed roles for renal involvement to predict molecular diagnosis among those with apparently sporadic presentation require further elucidation.
    MeSH term(s) Genetic Association Studies ; Humans ; Hypercalciuria ; Hyperparathyroidism, Primary/genetics ; Hyperparathyroidism, Primary/pathology ; Male ; Parathyroid Neoplasms/genetics ; Parathyroid Neoplasms/pathology ; Retrospective Studies ; Tumor Suppressor Proteins/genetics
    Chemical Substances Tumor Suppressor Proteins
    Language English
    Publishing date 2022-05-14
    Publishing country United States
    Document type Journal Article
    ZDB-ID 304266-2
    ISSN 1432-0827 ; 0944-0747 ; 0008-0594 ; 0171-967X
    ISSN (online) 1432-0827
    ISSN 0944-0747 ; 0008-0594 ; 0171-967X
    DOI 10.1007/s00223-022-00985-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Comparison of

    Patil, Virendra A / Goroshi, Manjunath R / Shah, Hina / Malhotra, Gaurav / Hira, Priya / Sarathi, Vijaya / Lele, Vikram R / Jadhav, Swati / Lila, Anurag / Bandgar, Tushar R / Shah, Nalini S

    World journal of nuclear medicine

    2020  Volume 19, Issue 2, Page(s) 99–105

    Abstract: The optimum imaging modality for the screening of multiple endocrine neoplasia type 1 (MEN1)-associated tumors is not well established. Here, we compare the performance of contrast-enhanced CT (CECT) ... ...

    Abstract The optimum imaging modality for the screening of multiple endocrine neoplasia type 1 (MEN1)-associated tumors is not well established. Here, we compare the performance of contrast-enhanced CT (CECT) versus
    Language English
    Publishing date 2020-01-29
    Publishing country Austria
    Document type Journal Article
    ZDB-ID 2911903-0
    ISSN 1607-3312 ; 1450-1147
    ISSN (online) 1607-3312
    ISSN 1450-1147
    DOI 10.4103/wjnm.WJNM_24_19
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Comparison of 68Ga-DOTA-NaI3-Octreotide/tyr3-octreotate positron emission tomography/computed tomography and contrast-enhanced computed tomography in localization of tumors in multiple endocrine neoplasia 1 syndrome

    Virendra Patil / Manjunath Goroshi / Hina Shah / Gaurav Malhotra / Priya Hira / Vijaya Sarathi / Vikram Lele / Swati Jadhav / Anurag Lila / Tushar Bandgar / Nalini Shah

    World Journal of Nuclear Medicine, Vol 19, Iss 02, Pp 99-

    2020  Volume 105

    Abstract: The optimum imaging modality for the screening of multiple endocrine neoplasia type 1 (MEN1)-associated tumors is not well established. Here, we compare the performance of contrast-enhanced CT (CECT) versus 68Ga DOTA-NOC/TATE PET/CT in MEN1 patients. The ...

    Abstract The optimum imaging modality for the screening of multiple endocrine neoplasia type 1 (MEN1)-associated tumors is not well established. Here, we compare the performance of contrast-enhanced CT (CECT) versus 68Ga DOTA-NOC/TATE PET/CT in MEN1 patients. The retrospective case record study is conducted at a tertiary health-care center. Thirty-four patients, who have undergone both CECT and 68Ga DOTA-NOC/TATE PET, were included in the analysis. CECT had higher per-lesion sensitivity than 68Ga DOTA-NOC/TATE PET/CT for the detection of parathyroid lesions, (82.6% vs. 24.6%, P < 0.001). 68Ga DOTA-NOC/TATE PET/CT had higher per-lesion sensitivity than CECT for the detection of metastases (85% vs. 47.5%, P < 0.001) and gastrinomas (90% vs. 10%, P = 0.003). When combined use of the two imaging modalities is compared to CECT alone (63.7% vs. 93.1%, P = 0.00012) and 68Ga-DOTA-NOC/TATE PET/CT alone (74.1% vs. 93.1%, P = 0.0057), it provided significantly higher per-lesion sensitivity for the detection of gastroenteropancreatic neuroendocrine tumors (GEP-NETs). 68Ga-DOTA-NOC/TATE PET was more sensitive for the detection of gastrinomas and metastases than CECT, whereas it was less sensitive for the detection of parathyroid lesions than CECT. The combined use of both the imaging modalities significantly increases the sensitivity for detection of GEP-NETs.
    Keywords 68ga-dota-nai3-octreotide/tyr3-octreotate positron emission tomography/computed tomography ; contrast enhanced computed tomography ; gastrointestinal-pancreatic neuroendocrine tumor ; multiple endocrine neoplasia type 1 imaging ; multiple endocrine neoplasia type 1 syndrome ; Medical physics. Medical radiology. Nuclear medicine ; R895-920
    Subject code 610
    Language English
    Publishing date 2020-04-01T00:00:00Z
    Publisher Wolters Kluwer Medknow Publications
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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