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  1. Article ; Online: Psychiatric causes of behavioural change in adults less than 65 years old.

    Wang, Dingding / Goveas, Richard Roshan

    Singapore medical journal

    2022  Volume 63, Issue 8, Page(s) 456–461

    MeSH term(s) Adult ; Humans ; Mental Disorders
    Language English
    Publishing date 2022-10-19
    Publishing country India
    Document type Journal Article
    ZDB-ID 604319-7
    ISSN 2737-5935 ; 0037-5675
    ISSN (online) 2737-5935
    ISSN 0037-5675
    DOI 10.4103/singaporemedj.SMJ-2021-305
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 589: Show issues Location:
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  2. Article: Multiple brain abscesses caused by

    Jin, Shanmu / Guo, Xiaopeng / Xing, Hao / Li, Dingding / Wang, Yu / Ma, Wenbin

    IDCases

    2023  Volume 34, Page(s) e01903

    Abstract: ... ...

    Abstract Nocardia
    Language English
    Publishing date 2023-10-03
    Publishing country Netherlands
    Document type Case Reports
    ZDB-ID 2745454-X
    ISSN 2214-2509
    ISSN 2214-2509
    DOI 10.1016/j.idcr.2023.e01903
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  3. Article ; Online: A rotational spectroscopy study of microsolvation effects on intramolecular proton transfer in trifluoroacetylacetone-(H

    Lv, Dingding / Chen, Xinlei / Jiang, Ningjing / Wang, Guanjun / Zeng, Xiaoqing / Fang, Wei / Li, Weixing / Zhou, Mingfei

    Physical chemistry chemical physics : PCCP

    2024  Volume 26, Issue 16, Page(s) 12530–12536

    Abstract: Trifluoroacetylacetone (TFAA) has two enol forms, which can switch to each ... ...

    Abstract Trifluoroacetylacetone (TFAA) has two enol forms, which can switch to each other
    Language English
    Publishing date 2024-04-24
    Publishing country England
    Document type Journal Article
    ZDB-ID 1476244-4
    ISSN 1463-9084 ; 1463-9076
    ISSN (online) 1463-9084
    ISSN 1463-9076
    DOI 10.1039/d4cp01061b
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  4. Article ; Online: Glottic impersonation by a laryngeal neoplasm.

    Liu, Hongjun / Ni, Wenwen / Zhang, Lijuan / Wang, Dingding / Li, Wenxian / Han, Yuan

    Canadian journal of anaesthesia = Journal canadien d'anesthesie

    2023  Volume 70, Issue 12, Page(s) 2006–2007

    Language English
    Publishing date 2023-10-26
    Publishing country United States
    Document type Journal Article
    ZDB-ID 91002-8
    ISSN 1496-8975 ; 0832-610X
    ISSN (online) 1496-8975
    ISSN 0832-610X
    DOI 10.1007/s12630-023-02621-0
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 109: Show issues Location:
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  5. Article ; Online: PHYTOCHROME INTERACTING FACTOR 4 regulates microtubule organization to mediate high temperature-induced hypocotyl elongation in Arabidopsis.

    Zhou, Dingding / Wang, Xiaohong / Wang, Xiangfeng / Mao, Tonglin

    The Plant cell

    2023  Volume 35, Issue 6, Page(s) 2044–2061

    Abstract: Hypocotyl elongation is an important morphological response during plant thermomorphogenesis. Multiple studies indicate that the transcription factor PHYTOCHROME-INTERACTING FACTOR 4 (PIF4) is a key regulator of high temperature-induced hypocotyl ... ...

    Abstract Hypocotyl elongation is an important morphological response during plant thermomorphogenesis. Multiple studies indicate that the transcription factor PHYTOCHROME-INTERACTING FACTOR 4 (PIF4) is a key regulator of high temperature-induced hypocotyl elongation. However, the underlying cellular mechanisms regarding PIF4-mediated hypocotyl elongation are largely unclear. In this study, we found that PIF4 regulates the PLANT U-BOX TYPE E3 UBIQUITIN LIGASE 31 (PUB31)-SPIRAL1 (SPR1) module and alters cortical microtubule reorganization to promote hypocotyl cell elongation during Arabidopsis thaliana (Arabidopsis) thermomorphogenesis. SPR1 loss-of-function mutants exhibit much shorter hypocotyls when grown at 28 °C, indicating a positive role for SPR1 in high ambient temperature-induced hypocotyl elongation. High ambient temperature induces SPR1 expression in a PIF4-dependent manner, and stabilizes SPR1 protein to mediate microtubule reorganization. Further investigation showed that PUB31 interacts with and ubiquitinates SPR1. In particular, the ubiquitinated effect on SPR1 was moderately decreased at high temperature, which was due to the direct binding of PIF4 to the PUB31 promoter and down-regulating its expression. Thus, this study reveals a mechanism in which PIF4 induces SPR1 expression and suppresses PUB31 expression, resulting in the accumulation and stabilization of SPR1 protein, and further promoting hypocotyl cell elongation by altering cortical microtubule organization during Arabidopsis thermomorphogenesis.
    MeSH term(s) Arabidopsis/metabolism ; Arabidopsis Proteins/genetics ; Arabidopsis Proteins/metabolism ; Hypocotyl/metabolism ; Phytochrome/metabolism ; Temperature ; Basic Helix-Loop-Helix Transcription Factors/metabolism ; Microtubules/metabolism ; Microtubule-Associated Proteins/metabolism
    Chemical Substances Arabidopsis Proteins ; Phytochrome (11121-56-5) ; Basic Helix-Loop-Helix Transcription Factors ; SPR1 protein, Arabidopsis ; Microtubule-Associated Proteins
    Language English
    Publishing date 2023-03-23
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 623171-8
    ISSN 1532-298X ; 1040-4651
    ISSN (online) 1532-298X
    ISSN 1040-4651
    DOI 10.1093/plcell/koad042
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    In stock of ZB MED Bonn / Germany

    Z 4952: Show issues

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  6. Article ; Online: Efficacy and safety of Chinese patent medicine compound preparation combined with routine treatment in vitiligo: A Bayesian network meta-analysis.

    Wang, Jianfeng / Wang, Dingding / Si, Guomin

    Medicine

    2023  Volume 102, Issue 41, Page(s) e35327

    Abstract: Background and purpose: Treating vitiligo in clinical practice is challenging. Furthermore, oral drugs used in Western medicine have considerable side effects and are unsuitable for long-term treatment. In contrast, Chinese patent medicines (CPMs) are ... ...

    Abstract Background and purpose: Treating vitiligo in clinical practice is challenging. Furthermore, oral drugs used in Western medicine have considerable side effects and are unsuitable for long-term treatment. In contrast, Chinese patent medicines (CPMs) are more suitable for long-term oral vitiligo treatment, but medical evidence of their efficacy and safety is lacking. Therefore, in this study, the efficacy and safety of CPMs were evaluated and ranked using a Bayesian network meta-analysis.
    Methods: Seven Chinese and English databases were searched for all relevant articles published up to February 2023. The Bayesian network meta-analysis method was used to analyze the extracted data to evaluate efficacy and safety.
    Results: Six common CPMs for treating vitiligo were selected in our study, and 48 targeted articles and 4446 patients were included. This study showed that Qubai Babuqi tablets (QT) were the most effective for short-term treatment of vitiligo, and that vitiligo capsules or pills (VCP) were the most effective for long-term treatment, together with compound Quchong Banjiuju pills (QP). In terms of surface area under the cumulative ranking curve (SUCRA) values, the order of efficacy of each treatment was as follows: QT (92.18%) > Taohong Qingxue pills (TP) (63.81%) > VCP (55.53%) > QP (50.72%) > Bailing tablets or capsules (BTC) (49.01%) > Baishi pills (BP) (35.69%)>routine therapy (RT) (3.1%) in terms of total effective rate and QT (92.05%) > VCP (71.50%) > QP (66.60%) > TP (42.95%) > BTC (39.66%) > BP (36.60%)>RT (0.6%) in terms of improvement rate. In addition, the safety of the 6 CPMs did not significantly differ in terms of adverse effects. The SUCRA values indicated that QT performed slightly worse than other drugs.
    Discussion: In treating vitiligo, QT is most effective but only suitable for short-term administration owing to its poor safety. VCP and QP could be used as first-choice long-term medications. TP may positively affect repigmentation in patients with limited lesion areas.
    MeSH term(s) Humans ; Vitiligo/drug therapy ; Nonprescription Drugs/adverse effects ; Network Meta-Analysis ; Bayes Theorem ; Drugs, Chinese Herbal/adverse effects ; Drug-Related Side Effects and Adverse Reactions
    Chemical Substances Nonprescription Drugs ; 4-chlorophenyl methyl sulfide (123-09-1) ; Drugs, Chinese Herbal
    Language English
    Publishing date 2023-10-13
    Publishing country United States
    Document type Meta-Analysis ; Journal Article
    ZDB-ID 80184-7
    ISSN 1536-5964 ; 0025-7974
    ISSN (online) 1536-5964
    ISSN 0025-7974
    DOI 10.1097/MD.0000000000035327
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Ua VI Zs.171: Show issues Location:
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  7. Article ; Online: Baicalin attenuates chronic unpredictable mild stress-induced hippocampal neuronal apoptosis through regulating SIRT1/PARP1 signaling pathway.

    Ma, Zhongxuan / Feng, Dingding / Rui, Wenjuan / Wang, Zhiqing

    Behavioural brain research

    2023  Volume 441, Page(s) 114299

    Abstract: Baicalin (BA), a flavonoid glycoside extracts from Scutellaria baicalensis Georgi, has been reported to exert antidepressant effects. Emerging evidence indicates that neuronal apoptosis plays a crucial role in the pathogenesis of depression. Poly (ADP- ... ...

    Abstract Baicalin (BA), a flavonoid glycoside extracts from Scutellaria baicalensis Georgi, has been reported to exert antidepressant effects. Emerging evidence indicates that neuronal apoptosis plays a crucial role in the pathogenesis of depression. Poly (ADP-ribose) polymerase-1 (PARP1) is established as a key regulator of the cellular apoptosis. In the present study, we explored whether BA exerts antidepressant effects by regulating PARP1 signaling pathway and elucidated the underlying mechanisms. We found that administration of BA (30 mg/kg, 60 mg/kg) alleviated chronic unpredictable mild stress (CUMS)-induced depressive-like behaviors by increasing sucrose consumption in sucrose preference test (SPT), improving activity status in open field test (OFT) and reducing rest time in tail suspension test (TST). Hematoxylin and eosin (HE) staining and Nissl staining showed that BA ameliorated CUMS-induced neuronal damage in the hippocampus. Moreover, BA significantly upregulated anti-apoptotic protein Bcl-2, downregulated pro-apoptotic protein Bax and cleaved-caspase-3 after CUMS in hippocampal of mice. Intriguingly, western blot and immunohistochemistry (IHC) results showed that the protein level of PARP1 was significantly increased in hippocampal tissue after CUMS, which was reversed by BA treatment. In primary hippocampal neurons (PHNs), BA abrogated the neuronal apoptosis caused by PARP1 overexpression. Meanwhile, BA significantly increased the protein level of SIRT1, SIRT1 inhibitor (EX-527) treatment reversed the effect of BA on reducing the protein level of PARP1 and neuronal apoptosis in CUMS-induced mice. Overall, our results indicated that BA attenuated the CUMS-induced hippocampal neuronal apoptosis through regulating the SIRT1/PARP1 signaling pathway.
    MeSH term(s) Mice ; Animals ; Depression/metabolism ; Sirtuin 1/metabolism ; Poly (ADP-Ribose) Polymerase-1/metabolism ; Poly (ADP-Ribose) Polymerase-1/pharmacology ; Antidepressive Agents/pharmacology ; Signal Transduction ; Flavonoids/pharmacology ; Flavonoids/metabolism ; Apoptosis ; Neurons/metabolism ; Hippocampus/metabolism ; Stress, Psychological/drug therapy ; Stress, Psychological/metabolism ; Disease Models, Animal
    Chemical Substances baicalin (347Q89U4M5) ; Sirtuin 1 (EC 3.5.1.-) ; Poly (ADP-Ribose) Polymerase-1 (EC 2.4.2.30) ; Antidepressive Agents ; Flavonoids ; Sirt1 protein, mouse (EC 3.5.1.-)
    Language English
    Publishing date 2023-01-12
    Publishing country Netherlands
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 449927-x
    ISSN 1872-7549 ; 0166-4328
    ISSN (online) 1872-7549
    ISSN 0166-4328
    DOI 10.1016/j.bbr.2023.114299
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1599: Show issues Location:
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  8. Article ; Online: Gas diffusion TiO

    Wang, Chongyi / Liu, Yuxin / Chen, Rong / Zhu, Xun / Ye, Dingding / Yang, Yang / Liao, Qiang

    Journal of hazardous materials

    2023  Volume 447, Page(s) 130769

    Abstract: In this work, a photocatalytic fuel cell (PFC) with a gas diffusion ... ...

    Abstract In this work, a photocatalytic fuel cell (PFC) with a gas diffusion TiO
    Language English
    Publishing date 2023-01-12
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 1491302-1
    ISSN 1873-3336 ; 0304-3894
    ISSN (online) 1873-3336
    ISSN 0304-3894
    DOI 10.1016/j.jhazmat.2023.130769
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  9. Article ; Online: The Association Between Quarantine Duration and Psychological Outcomes, Social Distancing, and Vaccination Intention During the Second Outbreak of COVID-19 in China.

    Chen, Lele / Wang, Dingding / Xia, Yuxin / Zhou, Renlai

    International journal of public health

    2022  Volume 67, Page(s) 1604096

    Abstract: Objectives: ...

    Abstract Objectives:
    MeSH term(s) COVID-19/epidemiology ; COVID-19/prevention & control ; China/epidemiology ; Cross-Sectional Studies ; Disease Outbreaks/prevention & control ; Humans ; Intention ; Physical Distancing ; Quarantine ; Vaccination/psychology
    Language English
    Publishing date 2022-03-07
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2274130-6
    ISSN 1661-8564 ; 1661-8556
    ISSN (online) 1661-8564
    ISSN 1661-8556
    DOI 10.3389/ijph.2022.1604096
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 843: Show issues Location:
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  10. Article: Early diagnosis and clinical application of systemic lupus erythematosus based on a nomogram model.

    Yang, Yalin / Huang, Dingding / Liu, Cuicui / Zhong, Ningxuan / Peng, You / Wang, Lulu / Xiao, Linlin / Zhao, Weiwei

    Heliyon

    2024  Volume 10, Issue 2, Page(s) e24523

    Abstract: Systemic lupus erythematosus (SLE) is a chronic autoimmune disease involving multi-system and multi-organ dysfunction, and is easily misdiagnosed early in the disease course. We aimed to accurately predict early SLE nomogram to provide a reference basis ... ...

    Abstract Systemic lupus erythematosus (SLE) is a chronic autoimmune disease involving multi-system and multi-organ dysfunction, and is easily misdiagnosed early in the disease course. We aimed to accurately predict early SLE nomogram to provide a reference basis for the early clinical diagnosis of SLE.
    Language English
    Publishing date 2024-01-14
    Publishing country England
    Document type Journal Article
    ZDB-ID 2835763-2
    ISSN 2405-8440
    ISSN 2405-8440
    DOI 10.1016/j.heliyon.2024.e24523
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