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  1. Article ; Online: Plasma synthesis of oxygen vacancy-rich CuO/Cu

    Yang, Zikun / Peng, Xiangfeng / Zheng, Jingxuan / Wang, Zhao

    Physical chemistry chemical physics : PCCP

    2023  Volume 25, Issue 42, Page(s) 29108–29119

    Abstract: Defect regulation and the construction of a heterojunction structure are effective strategies to improve the catalytic activity of catalysts. In this work, the rapid conversion of CuO to ... ...

    Abstract Defect regulation and the construction of a heterojunction structure are effective strategies to improve the catalytic activity of catalysts. In this work, the rapid conversion of CuO to Cu
    Language English
    Publishing date 2023-11-01
    Publishing country England
    Document type Journal Article
    ZDB-ID 1476244-4
    ISSN 1463-9084 ; 1463-9076
    ISSN (online) 1463-9084
    ISSN 1463-9076
    DOI 10.1039/d3cp03918h
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Comparative transcriptome analysis between rhesus macaques (

    Mao, Yu-Xiang / Li, Yamei / Yang, Zikun / Xu, Ning / Zhang, Shilong / Wang, Xuankai / Yang, Xiangyu / Sun, Qiang / Mao, Yafei

    Zoological research

    2024  Volume 45, Issue 2, Page(s) 299–310

    Abstract: Understanding gene expression variations between species is pivotal for deciphering the evolutionary diversity in phenotypes. Rhesus macaques ( ...

    Abstract Understanding gene expression variations between species is pivotal for deciphering the evolutionary diversity in phenotypes. Rhesus macaques (
    MeSH term(s) Humans ; Animals ; Macaca mulatta/genetics ; Macaca fascicularis/genetics ; Transcriptome ; Genomics ; Gene Expression Profiling/veterinary
    Language English
    Publishing date 2024-03-14
    Publishing country China
    Document type Journal Article
    ISSN 2095-8137
    ISSN 2095-8137
    DOI 10.24272/j.issn.2095-8137.2023.322
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Using combination of albumin to fibrinogen ratio and prognostic nutritional index model for predicting disease activity in patients with systemic lupus erythematosus.

    Zhao, Hongshuai / Huang, Zikun / Wang, Shiqian / Fu, Peng / Fu, Biqi / Guo, Yang / Li, Junming / Luo, Qing

    Lupus

    2024  Volume 33, Issue 5, Page(s) 490–501

    Abstract: Background: ...

    Abstract Background:
    MeSH term(s) Humans ; Nutrition Assessment ; Lupus Erythematosus, Systemic/diagnosis ; Lupus Erythematosus, Systemic/complications ; Fibrinogen ; Prognosis ; Retrospective Studies ; Biomarkers ; Albumins
    Chemical Substances Fibrinogen (9001-32-5) ; Biomarkers ; Albumins
    Language English
    Publishing date 2024-03-08
    Publishing country England
    Document type Journal Article
    ZDB-ID 1154407-7
    ISSN 1477-0962 ; 0961-2033
    ISSN (online) 1477-0962
    ISSN 0961-2033
    DOI 10.1177/09612033241238505
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3717: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  4. Article ; Online: Multiomics-integrated deep language model enables in silico genome-wide detection of transcription factor binding site in unexplored biosamples.

    Yang, Zikun / Li, Xin / Sheng, Lele / Zhu, Ming / Lan, Xun / Gu, Fei

    Bioinformatics (Oxford, England)

    2024  Volume 40, Issue 1

    Abstract: Motivation: Transcription factor binding sites (TFBS) are regulatory elements that have significant impact on transcription regulation and cell fate determination. Canonical motifs, biological experiments, and computational methods have made it possible ...

    Abstract Motivation: Transcription factor binding sites (TFBS) are regulatory elements that have significant impact on transcription regulation and cell fate determination. Canonical motifs, biological experiments, and computational methods have made it possible to discover TFBS. However, most existing in silico TFBS prediction models are solely DNA-based, and are trained and utilized within the same biosample, which fail to infer TFBS in experimentally unexplored biosamples.
    Results: Here, we propose TFBS prediction by modified TransFormer (TFTF), a multimodal deep language architecture which integrates multiomics information in epigenetic studies. In comparison to existing computational techniques, TFTF has state-of-the-art accuracy, and is also the first approach to accurately perform genome-wide detection for cell-type and species-specific TFBS in experimentally unexplored biosamples. Compared to peak calling methods, TFTF consistently discovers true TFBS in threshold tuning-free way, with higher recalled rates. The underlying mechanism of TFTF reveals greater attention to the targeted TF's motif region in TFBS, and general attention to the entire peak region in non-TFBS. TFTF can benefit from the integration of broader and more diverse data for improvement and can be applied to multiple epigenetic scenarios.
    Availability and implementation: We provide a web server (https://tftf.ibreed.cn/) for users to utilize TFTF model. Users can train TFTF model and discover TFBS with their own data.
    MeSH term(s) Binding Sites ; Multiomics ; Protein Binding ; Genome ; Transcription Factors/metabolism ; Computational Biology/methods
    Chemical Substances Transcription Factors
    Language English
    Publishing date 2024-01-11
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1422668-6
    ISSN 1367-4811 ; 1367-4803
    ISSN (online) 1367-4811
    ISSN 1367-4803
    DOI 10.1093/bioinformatics/btae013
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2374: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  5. Article ; Online: The Protective Effect of

    Wang, Tianci / Jia, Zikun / An, Canghai / Ren, Ping / Yang, Yiting / Wang, Wanting / Su, Ling

    Molecules (Basel, Switzerland)

    2023  Volume 28, Issue 24

    Abstract: This study's objective was to examine the protective effect and mechanism of a novel polysaccharide (AYP) ... ...

    Abstract This study's objective was to examine the protective effect and mechanism of a novel polysaccharide (AYP) from
    MeSH term(s) Mice ; Animals ; Gastrointestinal Microbiome ; RNA, Ribosomal, 16S ; Liver Diseases, Alcoholic/drug therapy ; Liver Diseases, Alcoholic/prevention & control ; Liver Diseases, Alcoholic/pathology ; Liver ; Polysaccharides/chemistry
    Chemical Substances RNA, Ribosomal, 16S ; Polysaccharides
    Language English
    Publishing date 2023-12-08
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 1413402-0
    ISSN 1420-3049 ; 1431-5165 ; 1420-3049
    ISSN (online) 1420-3049
    ISSN 1431-5165 ; 1420-3049
    DOI 10.3390/molecules28248003
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.MO 81: Show issues

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  6. Article ; Online: Cu-doped La

    Yang, Xue / Le, Fuhe / Zhou, Zikun / Jia, Wei / Zhou, Dehuo / Chen, Xianhao

    Dalton transactions (Cambridge, England : 2003)

    2023  Volume 52, Issue 20, Page(s) 6906–6914

    Abstract: The preparation of a high-efficiency and durable electrocatalyst for the alkaline hydrogen evolution reaction (HER) is essential for realizing renewable energy technologies. Herein, a series of ... ...

    Abstract The preparation of a high-efficiency and durable electrocatalyst for the alkaline hydrogen evolution reaction (HER) is essential for realizing renewable energy technologies. Herein, a series of La
    Language English
    Publishing date 2023-05-22
    Publishing country England
    Document type Journal Article
    ZDB-ID 1472887-4
    ISSN 1477-9234 ; 1364-5447 ; 0300-9246 ; 1477-9226
    ISSN (online) 1477-9234 ; 1364-5447
    ISSN 0300-9246 ; 1477-9226
    DOI 10.1039/d3dt00866e
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Four New Pale-Spored Species of

    Ma, Haixia / Song, Zikun / Pan, Xiaoyan / Qu, Zhi / Yang, Zhanen / Li, Yu / Zhu, Anhong

    Biology

    2022  Volume 11, Issue 6

    Abstract: ... ...

    Abstract Xylaria
    Language English
    Publishing date 2022-06-08
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2661517-4
    ISSN 2079-7737
    ISSN 2079-7737
    DOI 10.3390/biology11060885
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Smart Breeding Platform: A web-based tool for high-throughput population genetics, phenomics, and genomic selection.

    Li, Huihui / Li, Xin / Zhang, Peng / Feng, Yingwei / Mi, Junri / Gao, Shang / Sheng, Lele / Ali, Mohsin / Yang, Zikun / Li, Liang / Fang, Wei / Wang, Wensheng / Qian, Qian / Gu, Fei / Zhou, Wenbin

    Molecular plant

    2024  

    Language English
    Publishing date 2024-03-06
    Publishing country England
    Document type Journal Article
    ZDB-ID 2393618-6
    ISSN 1752-9867 ; 1674-2052
    ISSN (online) 1752-9867
    ISSN 1674-2052
    DOI 10.1016/j.molp.2024.03.002
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: ZmNF-YC1-ZmAPRG pathway modulates low phosphorus tolerance in maize.

    Bai, Yang / Yang, Qiuyue / Gan, Yuling / Li, Mei / Zhao, Zikun / Dong, Erfei / Li, Chaofeng / He, Di / Mei, Xiupeng / Cai, Yilin

    Journal of experimental botany

    2024  

    Abstract: Phosphorus (P) is an essential nutrient for plant growth and yield. Low phosphate-use-efficiency makes it important to clarify the molecular mechanism of low phosphorus stress. In our previous studies, a phosphorus efficiency gene ZmAPRG was identified. ... ...

    Abstract Phosphorus (P) is an essential nutrient for plant growth and yield. Low phosphate-use-efficiency makes it important to clarify the molecular mechanism of low phosphorus stress. In our previous studies, a phosphorus efficiency gene ZmAPRG was identified. Here, we further screened the upstream regulator ZmNF-YC1 of ZmAPRG by yeast one hybrid (Y1H) assay, and found it was a low Pi-inducible gene. The results of dual luciferase assays, expression analysis and ChIP-qPCR assays showed that ZmNF-YC1 is a positive regulator of ZmAPRG. Overexpression of ZmNF-YC1 improved low phosphorus tolerance whereas knockout of ZmNF-YC1 decreased low phosphorus tolerance in maize. Bimolecular fluorescence complementation (BiFC), Y2H and Y3H assay further showed that ZmNF-YC1 can interact with ZmNF-YB14, and recruit ZmNF-YA4/10 to form NF-Y complexes. Transcriptional activation assay confirmed that the NF-Y complexes can activate the promoters of ZmAPRG. Meanwhile, transcriptome and metabolome analyses indicated that overexpression of ZmAPRG improves low P tolerance by regulating lipid composition and photosynthetic capacity, and chlorophyll fluorescence parameters supplied evidence in support of this hypothesis. Furthermore, overexpression of ZmAPRG increased grain yield in inbred and hybrid maize under low P conditions. Taken together, our research revealed the low P tolerance mechanism of ZmNF-YC1-ZmAPRG pathway.
    Language English
    Publishing date 2024-02-23
    Publishing country England
    Document type Journal Article
    ZDB-ID 2976-2
    ISSN 1460-2431 ; 0022-0957
    ISSN (online) 1460-2431
    ISSN 0022-0957
    DOI 10.1093/jxb/erae068
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Bonn / Germany

    Z 55/29: Show issues

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  10. Article ; Online: Propensity score matched analysis of treatment outcomes in pediatric ureteropelvic junction obstruction: a comparison between horseshoe and non-horseshoe kidneys.

    Li, Jiayi / Shao, Zikun / Yang, Zhenzhen / Liu, Pei / Sun, Ning / Song, Hongcheng / Xie, Xianghui / Zhang, Weiping

    World journal of urology

    2024  Volume 42, Issue 1, Page(s) 282

    Abstract: Background: Pediatric hydronephrosis poses distinct challenges, particularly in cases involving horseshoe kidneys (HSK). This retrospective study compares treatment outcomes between HSK and non-horseshoe kidneys (NHSK) in pediatric ureteropelvic ... ...

    Abstract Background: Pediatric hydronephrosis poses distinct challenges, particularly in cases involving horseshoe kidneys (HSK). This retrospective study compares treatment outcomes between HSK and non-horseshoe kidneys (NHSK) in pediatric ureteropelvic junction obstruction (UPJO) patients.
    Methods: A retrospective cohort study included 35 patients with HSK and 790 patients with NHSK undergoing pyeloplasty. Preoperative, intraoperative, and postoperative parameters were evaluated. Propensity score matching (PSM) balanced patient characteristics in the NHSK group.
    Results: In comparison with NHSK, HSK exhibited a higher crossing vessel incidence (51.6% vs. 5.12%, P < 0.001) and smaller preoperative anteroposterior pelvic diameter (APD). Post 6 and 12 months, NHSK maintained a larger APD, with a higher P/C ratio at 12 months. PSM retained significantly higher crossing vessel incidence in HSK (51.6 vs. 3.61%, P < 0.001). Laparoscopic pyeloplasty (LP) in HSK showed lower postoperative length of stay (LOS). Postoperative ultrasound parameters favored NHSK. In HSK and NHSK with crossing vessels, HSK demonstrated higher complications even post-PSM (38.5% vs. 0%, P = 0.039).
    Conclusions: The study emphasizes the importance of recognizing crossing vessels in HSK-related hydronephrosis. Surgical success, although comparable between HSK and NHSK, requires tailored approaches. This investigation contributes valuable insights to pediatric urology, emphasizing personalized management for optimal outcomes.
    MeSH term(s) Humans ; Ureteral Obstruction/surgery ; Retrospective Studies ; Male ; Female ; Propensity Score ; Kidney Pelvis/surgery ; Treatment Outcome ; Child, Preschool ; Fused Kidney/complications ; Fused Kidney/surgery ; Child ; Urologic Surgical Procedures/methods ; Infant ; Cohort Studies ; Hydronephrosis/surgery
    Language English
    Publishing date 2024-05-02
    Publishing country Germany
    Document type Journal Article ; Comparative Study
    ZDB-ID 380333-8
    ISSN 1433-8726 ; 0724-4983
    ISSN (online) 1433-8726
    ISSN 0724-4983
    DOI 10.1007/s00345-024-04965-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1832: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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