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  1. Book: Improving transitions of care for patients with thromboembolic disease

    Owens, Gary M.

    (The American journal of managed care ; 20,4, Suppl.)

    2014  

    Author's details Gary M. Owens
    Series title The American journal of managed care ; 20,4, Suppl.
    Collection
    Language English
    Size S. S77 - S92
    Publisher Managed Care & Healthcare Communications
    Publishing place S.l.
    Publishing country United States
    Document type Book
    HBZ-ID HT018242695
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    Zs A 5353 -20,4,Suppl.- not available for loan Zeitschriften-Lesesaal

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  2. Article ; Online: Corrigendum to 'Deciphering silver nanoparticle perturbates effect and risk on soil enzymes worldwide: Insights from machine learning and soil property integration' [J. Hazard. Mater., 469 (2024), 134052].

    Zhang, Zhenjun / Lin, Jiajiang / Owens, Gary / Chen, Zuliang

    Journal of hazardous materials

    2024  Volume 470, Page(s) 134197

    Language English
    Publishing date 2024-04-09
    Publishing country Netherlands
    Document type Published Erratum
    ZDB-ID 1491302-1
    ISSN 1873-3336 ; 0304-3894
    ISSN (online) 1873-3336
    ISSN 0304-3894
    DOI 10.1016/j.jhazmat.2024.134197
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  3. Article ; Online: Deciphering silver nanoparticles perturbation effects and risks for soil enzymes worldwide: Insights from machine learning and soil property integration.

    Zhang, Zhenjun / Lin, Jiajiang / Owens, Gary / Chen, Zuliang

    Journal of hazardous materials

    2024  Volume 469, Page(s) 134052

    Abstract: Globally extensive research into how silver nanoparticles (AgNPs) affect enzyme activity in soils with differing properties has been limited by cost-prohibitive sampling. In this study, customized machine learning (ML) was used to extract data patterns ... ...

    Abstract Globally extensive research into how silver nanoparticles (AgNPs) affect enzyme activity in soils with differing properties has been limited by cost-prohibitive sampling. In this study, customized machine learning (ML) was used to extract data patterns from complex research, with a hit rate of Random Forest > Multiple Imputation by Chained Equations > Decision Tree > K-Nearest Neighbors. Results showed that soil properties played a pivotal role in determining AgNPs' effect on soil enzymes, with the order being pH > organic matter (OM) > soil texture ≈ cation exchange capacity (CEC). Notably, soil enzyme activity was more sensitive to AgNPs in acidic soil (pH < 5.5), while elevated OM content (>1.9 %) attenuated AgNPs toxicity. Compared to soil acidification, reducing soil OM content is more detrimental in exacerbating AgNPs' toxicity and it emerged that clay particles were deemed effective in curbing their toxicity. Meanwhile sand particles played a very different role, and a sandy soil sample at > 40 % of the water holding capacity (WHC), amplified the toxicity of AgNPs. Perturbation mapping of how soil texture alters enzyme activity under AgNPs exposure was generated, where soils with sand (45-65 %), silt (< 22 %), and clay (35-55 %) exhibited even higher probability of positive effects of AgNPs. The average calculation results indicate the sandy clay loam (75.6 %), clay (74.8 %), silt clay (65.8 %), and sandy clay (55.9 %) texture soil demonstrate less AgNPs inhibition effect. The results herein advance the prediction of the effect of AgNPs on soil enzymes globally and determine the soil types that are more sensitive to AgNPs worldwide.
    MeSH term(s) Soil/chemistry ; Silver/toxicity ; Silver/chemistry ; Clay ; Sand ; Metal Nanoparticles/toxicity ; Metal Nanoparticles/chemistry
    Chemical Substances Soil ; Silver (3M4G523W1G) ; Clay (T1FAD4SS2M) ; Sand
    Language English
    Publishing date 2024-03-15
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 1491302-1
    ISSN 1873-3336 ; 0304-3894
    ISSN (online) 1873-3336
    ISSN 0304-3894
    DOI 10.1016/j.jhazmat.2024.134052
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  4. Article ; Online: Old bones control smooth muscle clones.

    Serbulea, Vlad / Deaton, Rebecca A / Owens, Gary K

    Nature aging

    2023  Volume 3, Issue 1, Page(s) 9–10

    MeSH term(s) Clone Cells ; Muscle, Smooth
    Language English
    Publishing date 2023-04-25
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Comment
    ISSN 2662-8465
    ISSN (online) 2662-8465
    DOI 10.1038/s43587-022-00346-1
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  5. Article ; Online: Response by Owens and Deaton to Letter Regarding Article, "Dichotomous Roles of Smooth Muscle Cell-Derived MCP1 (Monocyte Chemoattractant Protein 1) in Development of Atherosclerosis".

    Owens, Gary K / Deaton, Rebecca A

    Arteriosclerosis, thrombosis, and vascular biology

    2022  Volume 43, Issue 1, Page(s) e64

    MeSH term(s) Humans ; Chemokine CCL2/metabolism ; Atherosclerosis/metabolism ; Cells, Cultured ; Myocytes, Smooth Muscle/metabolism
    Chemical Substances Chemokine CCL2
    Language English
    Publishing date 2022-12-21
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 1221433-4
    ISSN 1524-4636 ; 1079-5642
    ISSN (online) 1524-4636
    ISSN 1079-5642
    DOI 10.1161/ATVBAHA.122.318638
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1705: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  6. Article ; Online: Intensive ammonium fertilizer addition activates iron and carbon conversion coupled cadmium redistribution in a paddy soil under gradient redox conditions.

    Wu, Weiqin / Su, Shixun / Lin, Jiajiang / Owens, Gary / Chen, Zuliang

    The Science of the total environment

    2024  Volume 927, Page(s) 172179

    Abstract: While over-fertilization and nitrogen deposition can lead to the enrichment of nitrogen in soil, its effects on heavy metal fractions under gradient moisture conditions remains unclear. Here, the effect of intensive ammonium ( ... ...

    Abstract While over-fertilization and nitrogen deposition can lead to the enrichment of nitrogen in soil, its effects on heavy metal fractions under gradient moisture conditions remains unclear. Here, the effect of intensive ammonium (NH
    MeSH term(s) Cadmium/analysis ; Iron ; Soil/chemistry ; Carbon ; Fertilizers ; Oxidation-Reduction ; Ammonium Compounds ; Soil Pollutants/analysis ; Agriculture/methods ; Oryza/metabolism
    Chemical Substances Cadmium (00BH33GNGH) ; Iron (E1UOL152H7) ; Soil ; Carbon (7440-44-0) ; Fertilizers ; Ammonium Compounds ; Soil Pollutants
    Language English
    Publishing date 2024-04-04
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 121506-1
    ISSN 1879-1026 ; 0048-9697
    ISSN (online) 1879-1026
    ISSN 0048-9697
    DOI 10.1016/j.scitotenv.2024.172179
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 949: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  7. Article ; Online: Ferrous sulfide nanoparticles can be biosynthesized by sulfate-reducing bacteria: Synthesis, characterization and removal of heavy metals from acid mine drainage.

    Chen, Jinyang / Gan, Li / Han, Yonghe / Owens, Gary / Chen, Zuliang

    Journal of hazardous materials

    2024  Volume 466, Page(s) 133622

    Abstract: Ferrous sulfide nanoparticles (nFeS) have proven to be effective in removing heavy metals (HMs) from wastewater. One such approach, which has garnered much attention as a sustainable technology, is via the in situ microbial synthesis of nFeS. Here, a ... ...

    Abstract Ferrous sulfide nanoparticles (nFeS) have proven to be effective in removing heavy metals (HMs) from wastewater. One such approach, which has garnered much attention as a sustainable technology, is via the in situ microbial synthesis of nFeS. Here, a sulfate-reducing bacteria (SRB) strain, Geobacter sulfurreducens, was used to initially biosynthesize ferrous sulfide nanoparticles (SRB-nFeS) and thereafter remove HMs from acid mine drainage (AMD). SRB-nFeS was characterized by X-ray powder diffraction (XRD), scanning electron microscopy (SEM) coupled to an energy dispersive spectrometer (EDS), three-dimensional excitation-emission matrix (3D-EEM) spectroscopy, Fourier transform infrared (FTIR) spectroscopy and X-ray photoelectron spectroscopy (XPS). Such characterization showed that SRB mediated the reduction of SO
    MeSH term(s) Sulfates/chemistry ; Metals, Heavy/chemistry ; Desulfovibrio/metabolism ; Bacteria/metabolism ; Acids/metabolism ; Ferrous Compounds
    Chemical Substances ferrous sulfide (TH5J4TUX6S) ; Sulfates ; Metals, Heavy ; Acids ; Ferrous Compounds
    Language English
    Publishing date 2024-01-24
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 1491302-1
    ISSN 1873-3336 ; 0304-3894
    ISSN (online) 1873-3336
    ISSN 0304-3894
    DOI 10.1016/j.jhazmat.2024.133622
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  8. Article ; Online: Treatment of advanced atherosclerotic mice with ABT-263 reduced indices of plaque stability and increased mortality.

    Karnewar, Santosh / Karnewar, Vaishnavi / Shankman, Laura S / Owens, Gary K

    JCI insight

    2024  Volume 9, Issue 2

    Abstract: The use of senolytic agents to remove senescent cells from atherosclerotic lesions is controversial. A common limitation of previous studies is the failure to rigorously define the effects of senolytic agent ABT-263 (Navitoclax) on smooth muscle cells ( ... ...

    Abstract The use of senolytic agents to remove senescent cells from atherosclerotic lesions is controversial. A common limitation of previous studies is the failure to rigorously define the effects of senolytic agent ABT-263 (Navitoclax) on smooth muscle cells (SMC) despite studies claiming that these cells are the major source of senescent cells. Moreover, there are no studies on the effect of ABT-263 on endothelial cells (EC), which - along with SMC - comprise 90% of α-smooth muscle actin+ (α-SMA+) myofibroblast-like cells in the protective fibrous cap. Here we tested the hypothesis that treatment of advanced atherosclerotic mice with ABT-263 will reduce lesion size and increase plaque stability. SMC (Myh11-CreERT2-eYFP) and EC (Cdh5-CreERT2-eYFP) lineage tracing Apoe-/- mice were fed a western diet (WD) for 18 weeks, followed by ABT-263 at 100 mg/kg/bw for 6 weeks or 50 mg/kg/bw for 9 weeks. ABT-263 treatment did not change lesion size or lumen area of the brachiocephalic artery (BCA). However, ABT-263 treatment reduced SMC by 90% and increased EC contributions to lesions via EC-to-mesenchymal transition (EndoMT) by 60%. ABT-263 treatment also reduced α-SMA+ fibrous cap thickness by 60% and was associated with a > 50% mortality rate. Taken together, ABT-263 treatment of WD-fed Apoe-/- mice with advanced lesions resulted in multiple detrimental changes, including reduced indices of stability and increased mortality.
    MeSH term(s) Mice ; Animals ; Endothelial Cells ; Mice, Knockout, ApoE ; Atherosclerosis/drug therapy ; Apolipoproteins E ; Aniline Compounds ; Sulfonamides
    Chemical Substances navitoclax (XKJ5VVK2WD) ; Apolipoproteins E ; Aniline Compounds ; Sulfonamides
    Language English
    Publishing date 2024-01-23
    Publishing country United States
    Document type Journal Article
    ISSN 2379-3708
    ISSN (online) 2379-3708
    DOI 10.1172/jci.insight.173863
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  9. Article ; Online: Removal of As(III) using a microorganism sustained secrete laccase-straw oxidation system.

    Cai, Xiaonan / Xue, Chao / Owens, Gary / Chen, Zuliang

    Journal of hazardous materials

    2023  Volume 448, Page(s) 130967

    Abstract: While laccase oxidation is a novel and promising method for treating arsenite-containing wastewater, the high cost and unsustainability of commercially available enzymes indicate a need to investigate more cost-effective viable alternatives. Here, a ... ...

    Abstract While laccase oxidation is a novel and promising method for treating arsenite-containing wastewater, the high cost and unsustainability of commercially available enzymes indicate a need to investigate more cost-effective viable alternatives. Here, a microorganism sustained secrete laccase-straw oxidation system (MLOS) was established and subsequently evaluated for the removal of As(III). MLOS showed efficient biological As(III) oxidation, with an As(III) removal efficiency reaching 99.9% at an initial As(III) concentration of 1.0 mg·L
    MeSH term(s) Wastewater ; Laccase/metabolism ; Molecular Docking Simulation ; Oxidation-Reduction ; Arsenic/metabolism
    Chemical Substances Wastewater ; Laccase (EC 1.10.3.2) ; Arsenic (N712M78A8G)
    Language English
    Publishing date 2023-02-07
    Publishing country Netherlands
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1491302-1
    ISSN 1873-3336 ; 0304-3894
    ISSN (online) 1873-3336
    ISSN 0304-3894
    DOI 10.1016/j.jhazmat.2023.130967
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  10. Article ; Online: Enhanced activity of Fe/Mn nanoparticles using a response surface methodology and mechanism for removing oxytetracycline and copper ion.

    Wu, Jing / Weng, Xiulan / Owens, Gary / Chen, Zuliang

    Chemosphere

    2023  Volume 319, Page(s) 138057

    Abstract: As feed additives, oxytetracycline (OTC) and copper ion (Cu(II)) are often detected in livestock and poultry farming wastewater. To address this issue, firstly, the synthesis conditions of Fe/Mn nanoparticles (Fe/Mn NPs) were initially optimized using a ... ...

    Abstract As feed additives, oxytetracycline (OTC) and copper ion (Cu(II)) are often detected in livestock and poultry farming wastewater. To address this issue, firstly, the synthesis conditions of Fe/Mn nanoparticles (Fe/Mn NPs) were initially optimized using a response surface methodology (RSM) to yield highly active Fe/Mn NPs, where the application of RSM significantly increased the Fe/Mn NPs' efficiency in removing co-contamination OTC and Cu(II),respectively, from 45.8 to 86.2% and 14.9-67.2%. Secondly, scanning electron microscope and Nitrogen adsorption-desorption isotherms results showed that Fe/Mn NPs were composed of elliptic particles between 20 and 40 nm, a specific surface area of 59.5 m
    MeSH term(s) Animals ; Swine ; Oxytetracycline ; Copper/chemistry ; Wastewater ; Nanoparticles/chemistry ; Photoelectron Spectroscopy ; Adsorption ; Water Pollutants, Chemical/chemistry
    Chemical Substances Oxytetracycline (X20I9EN955) ; Copper (789U1901C5) ; Wastewater ; Water Pollutants, Chemical
    Language English
    Publishing date 2023-02-03
    Publishing country England
    Document type Journal Article
    ZDB-ID 120089-6
    ISSN 1879-1298 ; 0045-6535 ; 0366-7111
    ISSN (online) 1879-1298
    ISSN 0045-6535 ; 0366-7111
    DOI 10.1016/j.chemosphere.2023.138057
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2540: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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