Article ; Online: Enhancing LOD determination in gas chromatography: Validating the Hubaux-Vos method for gas concentration measurement.
2024 Volume 1720, Page(s) 464764
Abstract: The limit of detection (LOD) is a crucial measure in analytical methods, representing the smallest amount of a substance that can be distinguished from background noise. In the realm of gas chromatography (GC), however, determining LOD can be quite ... ...
Abstract | The limit of detection (LOD) is a crucial measure in analytical methods, representing the smallest amount of a substance that can be distinguished from background noise. In the realm of gas chromatography (GC), however, determining LOD can be quite subjective, leading to significant variability among researchers. In this study, we validate the Hubaux-Vos method, an International Standards Organization(ISO)-approved approach for determining LOD in gas concentration measurements, using a GC equipped with a discharge ionization detector (DID) and a dynamic dilution system. We employ a gas mixture certified reference material (CRM) of CO, CH |
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MeSH term(s) | Limit of Detection ; Chromatography, Gas/methods ; Calibration ; Reference Standards ; Indicator Dilution Techniques |
Language | English |
Publishing date | 2024-02-20 |
Publishing country | Netherlands |
Document type | Journal Article |
ZDB-ID | 1171488-8 |
ISSN | 1873-3778 ; 0021-9673 |
ISSN (online) | 1873-3778 |
ISSN | 0021-9673 |
DOI | 10.1016/j.chroma.2024.464764 |
Database | MEDical Literature Analysis and Retrieval System OnLINE |
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