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  1. Article ; Online: Michael J. Fox Foundation LRRK2 Consortium: geographical differences in returning genetic research data to study participants.

    Alcalay, Roy N / Aasly, Jan / Berg, Daniela / Bressman, Susan / Brice, Alexis / Brockmann, Kathrin / Chan, Piu / Clark, Lorraine / Cormier, Florence / Corvol, Jean-Christophe / Durr, Alexandra / Facheris, Maurizio / Farrer, Matthew / Foroud, Tatiana M / Gasser, Thomas / Giladi, Nir / Halter, Cheryl / Lang, Anthony / Langston, J William /
    Marras, Connie / Marti-Masso, Jose-Felix / Ruiz Martinez, Javier / Mejia-Santana, Helen / Mirelman, Anat / Pont-Sunyer, Claustre / Orr-Urtreger, Avi / Raymond, Deborah / Saunders-Pullman, Rachel / Schüle, Birgitt / Tanner, Caroline / Tolosa, Eduardo / Urkowitz, Alison / Vilas, Dolores / Wise, Adina / Marder, Karen

    Genetics in medicine : official journal of the American College of Medical Genetics

    2014  Volume 16, Issue 8, Page(s) 644–645

    MeSH term(s) Foundations/organization & administration ; Genetic Research ; Humans ; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2 ; Parkinson Disease/genetics ; Patient Access to Records/psychology ; Protein Serine-Threonine Kinases/genetics
    Chemical Substances LRRK2 protein, human (EC 2.7.11.1) ; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2 (EC 2.7.11.1) ; Protein Serine-Threonine Kinases (EC 2.7.11.1)
    Language English
    Publishing date 2014-07-31
    Publishing country United States
    Document type Letter ; Research Support, Non-U.S. Gov't
    ZDB-ID 1455352-1
    ISSN 1530-0366 ; 1098-3600
    ISSN (online) 1530-0366
    ISSN 1098-3600
    DOI 10.1038/gim.2014.55
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5059: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  2. Book: Trainingsfälle für die Heilpraktikerprüfung

    Herzog, Michael / Lang, Eva / Sengebusch, Jürgen

    2020  

    Author's details Michael Herzog, Eva Lang, Jürgen Sengebusch
    Keywords Kurzlehrbuch ; mündliche Prüfung ; Heilpraktiker ; Heilerlaubnis ; Heilpraktikeranwärter ; Prüfungsvorbereitung ; Heilpraktikerprüfung ; Fallgeschichten ; Trainingsfälle ; 201 ; Heilpraxis ; Anamnese ; Untersuchung ; Differentialdiagnose ; Mündliche Prüfung
    Subject Naturheilpraktiker ; Differentialdiagnostik ; Differenzialdiagnostik ; Differenzialdiagnose ;RR ; Krankenuntersuchung ; Ärztliche Untersuchung ; Medizinische Untersuchung ; Ärztliche Untersuchungstechnik ; Klinische Untersuchung ; Körperliche Untersuchung ; Anamneseerhebung
    Subject code 610
    Language German
    Size 251 Seiten, Illustrationen, 24 cm x 17 cm, 590 g
    Edition 2., aktualisierte und erweiterte Auflage
    Publisher Karl F. Haug
    Publishing place Stuttgart
    Publishing country Germany
    Document type Book
    Old title Vorangegangen ist
    HBZ-ID HT020526391
    ISBN 978-3-13-242665-8 ; 3-13-242665-2 ; 9783132426672 ; 9783132426665 ; 3132426679 ; 3132426660
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2020 A 1147 available for loan (reading room) Lesesaal EG

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  3. Book ; Thesis: Der Effekt von uni- und bilateraler, thalamischer, tiefer Hirnstimulation auf die Sprache bei Patienten mit Essentiellem Tremor

    Pochmann, Jil / Barbe, Michael Thomas / Lang-Roth, Ruth

    Akustik und Verständlichkeit = The effect of uni- and bilateral thalamic deep brain stimulation on speech in patients with esssential tremor : acoustics and intelligibility

    2021  

    Title variant The effect of uni- and bilateral thalamic deep brain stimulation on speech in patients with esssential tremor
    Institution Universitätsklinikum Köln / Klinik und Poliklinik für Neurologie
    Author's details vorgelegt von Jil Pochmann ; 1. Gutachter: Universitätsprofessor Dr. med. M. Barbe, 2. Gutachterin: Privatdozentin Dr. med. R. Lang-Roth ; aus dem Zentrum für Neurologie udn Psychiatrie der Universität zu Köln, Klinik und Poliklinik für Neurologie
    Subject code 610
    Language German
    Size 67 Blätter, Diagramme
    Publishing place Köln
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Dissertation, Universität zu Köln, 2021
    HBZ-ID HT021188594
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2022 D 10 order for loan Magazin

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  4. Book: Differenzialdiagnose für Heilpraktiker

    Herzog, Michael / Lang, Eva / Sengebusch, Jürgen

    Kompendium mit Steckbriefen und Mind-Maps

    2017  

    Author's details Michael Herzog, Eva Lang, Jürgen Sengebusch
    Keywords Differentialdiagnose ; Heilpraktiker
    Subject Naturheilpraktiker ; Differentialdiagnostik ; Differenzialdiagnostik ; Differenzialdiagnose ;RR
    Language German
    Size 208 Seiten, Illustrationen, 27 cm x 19.5 cm
    Edition 3., überarbeitete und erweiterte Auflage
    Publisher Haug
    Publishing place Stuttgart
    Publishing country Germany
    Document type Book
    HBZ-ID HT019205456
    ISBN 978-3-13-205961-0 ; 3-13-205961-7 ; 9783132059719 ; 9783132059818 ; 3132059714 ; 3132059811
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2017 A 243 available for loan (reading room) Lesesaal EG

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  5. Book: Differenzialdiagnose für Heilpraktiker

    Herzog, Michael / Lang, Eva / Sengebusch, Jürgen

    Kompendium mit Steckbriefen und Mind-Maps

    2013  

    Author's details Michael Herzog ; Eva Lang ; Jürgen Sengebusch
    Keywords Differentialdiagnose ; Heilpraktiker
    Subject Naturheilpraktiker ; Differentialdiagnostik ; Differenzialdiagnostik ; Differenzialdiagnose ;RR
    Language German
    Size 234 S. : Ill., graph. Darst.
    Edition 2., aktualisierte Aufl.
    Publisher Haug
    Publishing place Stuttgart
    Publishing country Germany
    Document type Book
    HBZ-ID HT017769024
    ISBN 978-3-8304-7649-8 ; 3-8304-7649-3 ; 9783830476504 ; 9783830476511 ; 3830476507 ; 3830476515
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2013 A 2510 available for loan (reading room) Lesesaal EG

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  6. Article ; Online: Sphingosine Prevents Rhinoviral Infections.

    Lang, Judith / Soddemann, Matthias / Edwards, Michael J / Wilson, Gregory C / Lang, Karl S / Gulbins, Erich

    International journal of molecular sciences

    2024  Volume 25, Issue 5

    Abstract: Rhinoviral infections cause approximately 50% of upper respiratory tract infections and novel treatment options are urgently required. We tested the effects of 10 μM to 20 μM sphingosine on the infection of cultured and freshly isolated human cells with ... ...

    Abstract Rhinoviral infections cause approximately 50% of upper respiratory tract infections and novel treatment options are urgently required. We tested the effects of 10 μM to 20 μM sphingosine on the infection of cultured and freshly isolated human cells with minor and major group rhinovirus in vitro. We also performed in vivo studies on mice that were treated with an intranasal application of 10 μL of either a 10 μM or a 100 μM sphingosine prior and after infection with rhinovirus strains 1 and 2 and determined the infection of nasal epithelial cells in the presence or absence of sphingosine. Finally, we determined and characterized a direct binding of sphingosine to rhinovirus. Our data show that treating freshly isolated human nasal epithelial cells with sphingosine prevents infections with rhinovirus strains 2 (minor group) and 14 (major group). Nasal infection of mice with rhinovirus 1b and 2 is prevented by the intranasal application of sphingosine before or as long as 8 h after infection with rhinovirus. Nasal application of the same doses of sphingosine exerts no adverse effects on epithelial cells as determined by hemalaun and TUNEL stainings. The solvent, octylglucopyranoside, was without any effect in vitro and in vivo. Mechanistically, we demonstrate that the positively charged lipid sphingosine binds to negatively charged molecules in the virus, which seems to prevent the infection of epithelial cells. These findings indicate that exogenous sphingosine prevents infections with rhinoviruses, a finding that could be therapeutically exploited. In addition, we demonstrated that sphingosine has no obvious adverse effects on the nasal mucosa. Sphingosine prevents rhinoviral infections by a biophysical mode of action, suggesting that sphingosine could serve to prevent many viral infections of airways and epithelial cells in general. Future studies need to determine the molecular mechanisms of how sphingosine prevents rhinoviral infections and whether sphingosine also prevents infections with other viruses inducing respiratory tract infections. Furthermore, our studies do not provide detailed pharmacokinetics that are definitely required before the further development of sphingosine.
    MeSH term(s) Humans ; Animals ; Mice ; Sphingosine ; Nasal Mucosa ; Enterovirus Infections ; Epithelial Cells ; Rhinovirus ; Respiratory Tract Infections
    Chemical Substances Sphingosine (NGZ37HRE42)
    Language English
    Publishing date 2024-02-20
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms25052486
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Book: Differenzialdiagnose für Heilpraktiker

    Herzog, Michael / Lang, Eva / Sengebusch, Jürgen

    Kompendium mit Steckbriefen und Mind-Maps® ; 34 Tabellen

    2011  

    Author's details Michael Herzog ; Eva Lang ; Jürgen Sengebusch
    Keywords Differentialdiagnose ; Heilpraktiker
    Subject Naturheilpraktiker ; Differentialdiagnostik ; Differenzialdiagnostik ; Differenzialdiagnose ;RR
    Language German
    Size XIV, 210 S. : Ill., 240 mm x 170 mm
    Publisher Haug in MVS
    Publishing place Stuttgart
    Publishing country Germany
    Document type Book
    HBZ-ID HT016645437
    ISBN 978-3-8304-7362-6 ; 3-8304-7362-1
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2011 A 13 order for loan Magazin

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  8. Article ; Online: Republished:Delayed aneurysm rupture following treatment with the WEB embolization device.

    Gross, Bradley A / Lang, Michael J

    Journal of neurointerventional surgery

    2022  Volume 15, Issue 3, Page(s) e5

    Abstract: Delayed rupture of an aneurysm following WEB embolization has not yet been reported. We present a case of a multiply ruptured anterior communicating artery aneurysm treated via WEB embolization. A post-treatment CT scan confirmed no evidence of ... ...

    Abstract Delayed rupture of an aneurysm following WEB embolization has not yet been reported. We present a case of a multiply ruptured anterior communicating artery aneurysm treated via WEB embolization. A post-treatment CT scan confirmed no evidence of rebleeding during treatment. Four hours after treatment, the patient developed an acute, significant increase in intracranial pressure with bloody ventriculostomy output, with CT scan demonstrating new parenchymal and intraventricular hemorrhage. The aneurysm was subsequently treated via microsurgical clipping that did not identify an "uncovered" bleb or rupture source.
    MeSH term(s) Humans ; Subarachnoid Hemorrhage/therapy ; Intracranial Aneurysm/therapy ; Intracranial Aneurysm/surgery ; Embolization, Therapeutic/adverse effects ; Aneurysm, Ruptured/therapy ; Aneurysm, Ruptured/surgery ; Neurosurgical Procedures ; Treatment Outcome
    Language English
    Publishing date 2022-02-09
    Publishing country England
    Document type Case Reports ; Journal Article
    ZDB-ID 2514982-9
    ISSN 1759-8486 ; 1759-8478
    ISSN (online) 1759-8486
    ISSN 1759-8478
    DOI 10.1136/neurintsurg-2021-017439.rep
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6845: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  9. Book: Trainingsfälle für die Heilpraktikerprüfung

    Herzog, Michael / Lang, Eva / Sengebusch, Jürgen

    21 Tab

    2011  

    Author's details Michael Herzog ; Eva Lang ; Jürgen Sengebusch
    Keywords Anamnese ; Untersuchung ; Differentialdiagnose ; Mündliche Prüfung ; Heilpraktiker
    Subject Naturheilpraktiker ; Differentialdiagnostik ; Differenzialdiagnostik ; Differenzialdiagnose ;RR ; Krankenuntersuchung ; Ärztliche Untersuchung ; Medizinische Untersuchung ; Ärztliche Untersuchungstechnik ; Klinische Untersuchung ; Körperliche Untersuchung ; Anamneseerhebung
    Language German
    Size VII, 164 S., 240 mm x 170 mm
    Publisher Haug, MVS Med.-Verl
    Publishing place Stuttgart
    Publishing country Germany
    Document type Book
    HBZ-ID HT016715692
    ISBN 978-3-8304-7361-9 ; 3-8304-7361-3
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2011 A 605 order for loan Magazin

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  10. Book: Blickdiagnose für Heilpraktiker

    Herzog, Michael / Lang, Eva / Sengebusch, Jürgen

    Bildatlas für Prüfung und Praxis ; mit 7 Tabellen

    2010  

    Author's details Michael Herzog ; Eva Lang ; Jürgen Sengebusch
    Keywords Visuelle Diagnostik
    Subject Blickdiagnostik ; Blickdiagnose
    Language German
    Size VIII, 239 S. : zahlr. Ill., 27 cm
    Publisher Haug
    Publishing place Stuttgart
    Publishing country Germany
    Document type Book
    Note Literaturangaben
    HBZ-ID HT016495221
    ISBN 978-3-8304-7360-2 ; 3-8304-7360-5
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2010 A 4537 order for loan Magazin

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