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Article: Forecasting demand for blood products: Towards inventory management of a perishable product.

Thakur, Sanjay Kumar / Sinha, Anil Kumar / Negi, Dinesh Kumar / Singh, Sompal

2024 Volume 20, Issue 1, Page(s) 20–28

Abstract: Forecasting consumption of blood products can reduce their order frequency by 60% and inventory level by 40%. This also prevents shortage by balancing demand and supply. The study aimed to establish a "Simple Average with Mean Annual Increment" (SAMAI) ... ...

Abstract	Forecasting consumption of blood products can reduce their order frequency by 60% and inventory level by 40%. This also prevents shortage by balancing demand and supply. The study aimed to establish a "Simple Average with Mean Annual Increment" (SAMAI) method of time series forecasting and to compare its results with those of ARIMA, ratio to trend, and simple average to forecast demand of blood products. Monthly demand data of blood component from January 2017 to December 2022 (data set I) was used for creating a forecasting model. To avoid the effect of COVID19 pandemic instead of actual data of year 2020 and 2021, average monthly values of previous three years were used (data set II). The data from January to July 2023 were used as testing data set. To assess the fitness of model MAPE (Mean Absolute Percentage Error) was used. By SAMAI method MAPE were 18.82%, 13.392%, 14.516% and 27.637% respectively for of blood donation, blood issue, RDP issue and FFP issue for data set I. By Simple Average method MAPE were 20.05%, 12.09%, 29.06% and 34.85%, respectably. By Ratio-to-Trend method MAPE were 21.08%, 21.65%, 25.62% and 39.95% respectively. By SARIMA method MAPE were 12.99%, 19.59%, 37.15% and 31.94% respectively. The average MAPE was lower in data set II by all tested method and overall MAPE was lower by SAMAI method. The SAMAI method is simple and easy to perform. It can be used in the forecasting of blood components demand in medical institution without knowledge of advanced statistics.
Language	English
Publishing date	2024-01-31
Publishing country	Singapore
Document type	Journal Article
ZDB-ID	2203786-X
ISSN	0973-2063
ISSN	0973-2063
DOI	10.6026/973206300200020
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Article ; Online: Effect of COVID-19 pandemic on blood transfusion service: an experience from a regional blood transfusion center.

Thakur, Sanjay K / Sinha, Anil K / Negi, Dinesh K / Singh, Sompal

Blood science (Baltimore, Md.)

2023 Volume 5, Issue 3, Page(s) 209–217

Abstract: The unforeseen and uncertain life-threatening situation of the COVID-19 pandemic dramatically affected all areas of the human daily work schedule. This study was designed to assess the impact of the COVID-19 pandemic on blood transfusion services and ... ...

Abstract	The unforeseen and uncertain life-threatening situation of the COVID-19 pandemic dramatically affected all areas of the human daily work schedule. This study was designed to assess the impact of the COVID-19 pandemic on blood transfusion services and discuss the adopted confrontation measures for uninterrupted blood supply during the pandemic situation. The data on blood donation, blood component preparation, and issue from January 2019 to December 2022 were collected from the inventory registers of the RBTC, Delhi, India. Compared to the non-pandemic year 2019, during the year 2020, all variables decreased gradually. The observed maximum decrease in variables such as blood collection (-79.16%) in the month of October, blood issue (-71.61%) in the month of August, random donor platelets (RDP) preparation (-98.09%) in the month of October, RDP issue (-86.08%) in the month of September, fresh frozen plasma (FFP) preparation (-100%) in the month of October, and FFP issue (-96.08%) in the month of July with an annual decrease of -45.52%, -42.87%, -33.00%, -59.79%, -40.98%, and -54.48%, respectively, as compared to year 2019. Compared to year 2020, in year 2021, the annual increase in blood collection, blood issue, FFP preparation, FFP issue, RDP preparation, and RDP issue was +50.20%, +21.68%, +65.31%, +78.52%, +116.23%, and +213.30%, respectively. Our study results show that the COVID-19 pandemic has significantly affected blood transfusion services at our blood bank. The adopted coping strategies to maintain the safe and uninterrupted blood transfusion chain at our blood bank gave us lessons for future preparedness if faced with a similar situation.
Language	English
Publishing date	2023-05-24
Publishing country	United States
Document type	Journal Article
ISSN	2543-6368
ISSN (online)	2543-6368
DOI	10.1097/BS9.0000000000000161
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Article: Phenotype, allele and genotype frequency distribution of ABO and Rh(D) blood group among blood donors attending regional blood transfusion centre in Delhi, India.

Thakur, Sanjay Kumar / Singh, Sompal / Negi, Dinesh Kumar / Sinha, Anil Kumar

Bioinformation

2023 Volume 19, Issue 4, Page(s) 385–391

Abstract: The ABO and Rh blood group phenotypes, alleles, and genotype frequencies have many biological and medical implications. The frequency differs broadly according to races, geographical borders and ethnicity, even within the same region. This study was ... ...

Abstract	The ABO and Rh blood group phenotypes, alleles, and genotype frequencies have many biological and medical implications. The frequency differs broadly according to races, geographical borders and ethnicity, even within the same region. This study was designed to determine the frequency of ABO and Rh blood groups among blood donors attending the regional blood transfusion centre in Delhi. The gel card method was used to determine the ABO and Rh(D) blood groups of donors who donated blood between January 1, 2020, and June 30, 2022. The assumption of Hardy-Weinberg equilibrium was used to determine allele and genotype frequencies of blood donors. A total of 16,925 blood units were donated during the study period. Donors phenotype frequencies of ABO were as follows: 'A' (23.88%), 'B' (37.38%), 'AB' (9.97%) and 'O '(29.27%). Rh(D)+Ve (D) were (94.9%) and Rh(D)-Ve (d) were (5.01%), which follow an order of B > O > A > AB and Rh-D > d for Rh. Donors ABO and Rh (D) allele frequencies were I
Language	English
Publishing date	2023-04-30
Publishing country	Singapore
Document type	Journal Article
ZDB-ID	2203786-X
ISSN	0973-2063
ISSN	0973-2063
DOI	10.6026/97320630019385
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Article ; Online: Green urine in a postoperative child

Anil Negi / Surabhi Chandra

International Journal of Surgery and Medicine, Vol 7, Iss 2, Pp 20-

A case report

2021 Volume 22

Abstract: Introduction: Green discolouration of urine is a not so common finding. Case report: We present a five-year-old male child who had a transient episode of green urine in the postoperative period. The patient was admitted for closure of stoma (ileostomy) ... ...

Abstract	Introduction: Green discolouration of urine is a not so common finding. Case report: We present a five-year-old male child who had a transient episode of green urine in the postoperative period. The patient was admitted for closure of stoma (ileostomy) and correction of enterocutaneous fistula. In the postoperative period, the paediatrician noticed green urine. After ruling out other medical and surgery-related causes of green urine we concluded that the cause of green urine was Methylene blue dye which had been used intraoperatively to delineate the enterocutaneous fistulous tract. Conclusion: Methylene blue is an important cause of green urine.
Keywords	green urine ; methylene blue ; post operative ; case report ; Medicine ; R
Language	English
Publishing date	2021-04-01T00:00:00Z
Publisher	Bulgarian Association of Young Surgeons
Document type	Article ; Online
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Article: Prevalence of TTI among Indian blood donors.

Thakur, Sanjay Kumar / Singh, Sompal / Negi, Dinesh Kumar / Sinha, Anil Kumar

Bioinformation

2023 Volume 19, Issue 5, Page(s) 582–589

Abstract: Transfusion Transmissible Infections (TTIs) such as human immune-deficiency virus (HIV-I/II), hepatitis B virus (HBV), Hepatitis C virus (HCV), Malaria parasite (MP) and syphilis can spread through contaminated blood or blood products. The present study ... ...

Abstract	Transfusion Transmissible Infections (TTIs) such as human immune-deficiency virus (HIV-I/II), hepatitis B virus (HBV), Hepatitis C virus (HCV), Malaria parasite (MP) and syphilis can spread through contaminated blood or blood products. The present study was designed to analyze the prevalence of TTIs and their association with blood group, among the blood donors of Delhi. Blood group was determined by hem-agglutination using Gel card. HIV, HBV, and HCV test was performed by ELISA, syphilis by RPR and MP rapid card method. A total Transfusion Transmissible Infections (TTIs) such as human immune-deficiency virus (HIV-I/II), hepatitis B virus (HBV), Hepatitis C virus (HCV), Malaria parasite (MP) and syphilis can spread through contaminated blood or blood products. The present study was designed to analyze the prevalence of TTIs and their association with blood group, among the blood donors of Delhi. Blood group was determined by hem-agglutination using Gel card. HIV, HBV, and HCV test was performed by ELISA, syphilis by RPR and MP rapid card method. A total of 345(2.038%) blood donors were positive for TTIs. Prevalence of HBV, HCV, HIV-I/II, syphilis and MP were 188(1.111%), 73(0.431%), 34(0.201%), 49(0.29%) and 1(0.006%) respectively. Our result shows a trend of decrease in prevalence of TTIs; 2.267%, 2.111% and 1.614% between the year 2020, 2021 and 2022 respectively. Significant association of syphilis infection (P=0.036) and HCV infection (P=0.012) with ABO blood group antigen was observed. Blood group O donors were 1.81 times more infected with syphilis compared to donor having A and B antigen. Donors having blood group antigen B were 1.80 times more infected with HCV compared to donor not having B antigen. HBV and HIV prevalence found to be not associated with ABO and Rh blood group antigens. A low prevalence of TTIs positivity was observed among blood donors. Public awareness, proper counseling, medical examination and testing can help to minimize TTIs. Our study results shows ABO blood group has an association with HCV and VDRL infection.
Language	English
Publishing date	2023-05-31
Publishing country	Singapore
Document type	Journal Article
ZDB-ID	2203786-X
ISSN	0973-2063
ISSN	0973-2063
DOI	10.6026/97320630019582
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Article: Alloantibody among Thalassemia patients receiving multiple blood transfusions at a tertiary care hospital in India.

Thakur, Sanjay Kumar / Sinha, Anil Kumar / Jahan, Aarzoo / Mathur, Alka / Negi, Dinesh Kumar / Singh, Sompal

Bioinformation

2023 Volume 19, Issue 4, Page(s) 362–368

Abstract: Regular blood transfusion is a lifesaving treatment for thalassemia patients; however, it exposes them to multiple alloantigens. The present study was designed to assess the frequency of alloantibodies in thalassemia patients receiving multiple blood ... ...

Abstract	Regular blood transfusion is a lifesaving treatment for thalassemia patients; however, it exposes them to multiple alloantigens. The present study was designed to assess the frequency of alloantibodies in thalassemia patients receiving multiple blood transfusions. Blood samples were tested by Gel card method for ABO, Rh, Direct Antiglobulin Test (DAT), Indirect Antiglobulin Test (IAT), Auto Control (AC) and presence of alloantibody. Alloantibody screening and identification were performed using commercial 3-cell and 11-cell identification panels. Of a total of 66 thalassemia patients, 37 were male and 29 were female, with a mean age of 15.63±5.93 years and a range of 4.0 to 29.0 years. The ABO profiles of thalassemia patients were B-33, A-19, O-11, and AB-3, with 63 Rh-D positives and 3 Rh-D negatives. An average of 533.39±284.95 units were transfused an average of 304±119.65 times. Positive cases for DAT were 29(43.93%), AC was 26(39.39%) and IAT was 4(6.06%). Nine (13.636%) patients had developed alloantibodies, in which anti-K was seen in 5(27.77%), anti-Kp
Language	English
Publishing date	2023-04-30
Publishing country	Singapore
Document type	Journal Article
ZDB-ID	2203786-X
ISSN	0973-2063
ISSN	0973-2063
DOI	10.6026/97320630019362
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Article ; Online: Analysis on scattering characteristics of Love-type wave due to surface irregularity in a piezoelectric structure.

Negi, Anil / Kumar Singh, Abhishek

The Journal of the Acoustical Society of America

2019 Volume 145, Issue 6, Page(s) 3756

Abstract: Surface irregularity in piezoelectric sensors causes scattering of Love-type waves, which may lead to significant signal insertion loss. Also, as the reflected wave field in the piezoelectric sensor is increased due to surface irregularity, the input ... ...

Abstract	Surface irregularity in piezoelectric sensors causes scattering of Love-type waves, which may lead to significant signal insertion loss. Also, as the reflected wave field in the piezoelectric sensor is increased due to surface irregularity, the input interdigital transducer (IDT) can be damaged. The present analysis confers the characteristics of Love-type waves scattered through surface irregularity in piezoelectric composite structures with different shaped surface irregularity, e.g., rectangular shaped, parabolic shaped, and triangular notch shaped. The expressions of phase and group velocities of scattered Love-type waves are derived for electrically open and short conditions. Also, expressions of mechanical displacement and electrical potential function due to incident and scattered Love-type waves are deduced for both electrical conditions. It is reported from the analysis that the increase in vertical irregularity parameter causes stronger reflected wave fields. Also, with the increase in piezoelectricity of the superficial layer, signal insertion loss and strength of reflected wave field diminish.
Language	English
Publishing date	2019-06-22
Publishing country	United States
Document type	Journal Article
ZDB-ID	219231-7
ISSN	1520-8524 ; 0001-4966
ISSN (online)	1520-8524
ISSN	0001-4966
DOI	10.1121/1.5102165
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Article: Link between human ABO blood groups with diseases influencing blood donors and recipients frequency at RBTC, Delhi, India.

Thakur, Sanjay Kumar / Sompal, Singh / Dinesh Kumar, Negi / Sinha, Anil Kumar

Bioinformation

2023 Volume 19, Issue 5, Page(s) 576–581

Abstract: Blood groups had associations with many diseases that affect blood transfusion services by increasing or decreasing the blood demand of particular blood group. The present study was designed to compare the frequency of ABO and Rh blood groups among blood ...

Abstract	Blood groups had associations with many diseases that affect blood transfusion services by increasing or decreasing the blood demand of particular blood group. The present study was designed to compare the frequency of ABO and Rh blood groups among blood donors and blood component recipients. The ABO and Rh(D) blood groups of donors and recipients were determined using Gel card method. The frequency of blood donors and blood component recipients from January 1, 2020, to December 31, 2023, at regional blood transfusion centre of Delhi, were compared using χ² test. The ABO blood group frequencies of blood donors (n=23025) were: A(23.1%), B(37.53%), AB(10.09%), and O(29.29%). The blood issue (n=20255) was significantly (p=0.0000) higher in A(24.96%), B(39.92%), and lower in AB(9.76%) and O(25.37%). The RDP issue (n=7239) was significantly (p=0.0000) higher in A(24.71%), B(39.34%), and AB(11.53%) and lower in O(24.41%). The FFP issue (n=4164) was significantly (p=0.00024) higher in AB (12.3%) and lower in A (22.05%), B(37.32%), and O(28.14%). The difference between the blood donor frequencies of Rh(D)+Ve(95.19%) and Rh(D)-Ve(4.81%) and the blood issued by Rh(D)+Ve(95.06%) and Rh(D)-Ve(4.94%) was statistically not significant(P=0.52).Blood issues were higher in blood group A and B than in O, platelet issues were higher in A, B and AB than in O, and FFP issues were higher in the AB. Non-O blood groups may have a higher frequency of blood transfusions, while O blood groups may have a protective influence against diseases due to their innate immune response.
Language	English
Publishing date	2023-05-31
Publishing country	Singapore
Document type	Journal Article
ZDB-ID	2203786-X
ISSN	0973-2063
ISSN	0973-2063
DOI	10.6026/97320630019576
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Article ; Online: First report of '

Gupta, Shivani / Handa, Anil / Brakta, Ajay / Negi, Gulshan / Tiwari, Rahul Kumar / Lal, Milan Kumar / Kumar, Ravinder

PeerJ

2023 Volume 11, Page(s) e15926

Abstract: The almond, a commercially important tree nut crop worldwide, is native to the Mediterranean region. Stone fruit trees are affected by at least 14 ' ...

Abstract	The almond, a commercially important tree nut crop worldwide, is native to the Mediterranean region. Stone fruit trees are affected by at least 14 '
MeSH term(s)	Phytoplasma/genetics ; Phylogeny ; Prunus dulcis ; India ; Aster Plant ; Coloring Agents ; DNA, Ribosomal
Chemical Substances	Coloring Agents ; DNA, Ribosomal
Language	English
Publishing date	2023-08-28
Publishing country	United States
Document type	Journal Article
ZDB-ID	2703241-3
ISSN	2167-8359 ; 2167-8359
ISSN (online)	2167-8359
ISSN	2167-8359
DOI	10.7717/peerj.15926
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Article: Comparison of Two High-Pressure Liquid Chromatography Instruments Bio-Rad Variant-II and Tosoh HLC-723G11 in the Evaluation of Hemoglobinopathies.

Chopra, Parul / Bhardwaj, Sunanda / Negi, Pushkar / Arora, Anil

Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion

2020 Volume 36, Issue 4, Page(s) 725–732

Abstract: Hemoglobin High-performance liquid chromatography (Hb HPLC) is a standard first-line technique for diagnosis of thalassemia and hemoglobinopathies. We compared two HPLC systems for detection and quantification of normal and abnormal Hb fractions. EDTA ... ...

Abstract	Hemoglobin High-performance liquid chromatography (Hb HPLC) is a standard first-line technique for diagnosis of thalassemia and hemoglobinopathies. We compared two HPLC systems for detection and quantification of normal and abnormal Hb fractions. EDTA samples from 100 normal healthy subjects and 107 subjects affected with hemoglobinopathies or carriers were analysed using HPLC systems Tosoh HLC-723G11 and Bio-Rad Variant-II. Retention time (RT) and area of peaks for HbA2, HbF and other structural variants were compared. In discrepant cases samples were run on Sebia Capillary zone electrophoresis (CZE) for confirmation of results (39 out of 107 cases with HbE, HbD Iran, Hb Lepore and HbQ). Measurement of HbA2 and HbF in normal samples and HbF in those with variant Hbs showed good correlation by both analyzers (
Language	English
Publishing date	2020-06-19
Publishing country	India
Document type	Journal Article
ZDB-ID	2422370-0
ISSN	0974-0449 ; 0971-4502
ISSN (online)	0974-0449
ISSN	0971-4502
DOI	10.1007/s12288-020-01298-5
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