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Article ; Online: Self-powered triboelectric nanogenerator sensor for detecting humidity level and monitoring ethanol variation in a simulated exhalation environment.

Mohamadbeigi, Nima / Shooshtari, Leyla / Fardindoost, Somayeh / Vafaiee, Mohaddese / Iraji Zad, Azam / Mohammadpour, Raheleh

Scientific reports

2024 Volume 14, Issue 1, Page(s) 1562

Abstract: Respiration stands as a vital process reflecting physiological and pathological human health status. Exhaled breath analysis offers a facile, non-invasive, swift, and cost-effective approach for diagnosing and monitoring diseases by detecting ... ...

Abstract	Respiration stands as a vital process reflecting physiological and pathological human health status. Exhaled breath analysis offers a facile, non-invasive, swift, and cost-effective approach for diagnosing and monitoring diseases by detecting concentration changes of specific biomarkers. In this study, we employed Polyethylene oxide/copper (I) oxide composite nanofibers (PCNFs), synthesized via the electrospinning method as the sensing material to measure ethanol levels (1-200 ppm) in an exhaled breath simulator environment. The integrated contact-separation triboelectric nanogenerator was utilized to power the self-powered PCNFs exhaled breath sensor. The PCNFs-based gas sensor demonstrates promising results with values of 0.9 and 3.2 for detecting 5 ppm and 200 ppm ethanol, respectively, in the presence of interfering gas at 90% relative humidity (RH). Notably, the sensor displayed remarkable ethanol selectivity, with ratios of 10:1 to methanol and 25:1 to acetone. Response and recovery times for 200 ppm ethanol at 90 RH% were rapid, at 2.7 s and 5.8 s, respectively. The PCNFs-based exhaled breath sensor demonstrated consistent and stable performance in practical conditions, showcasing its potential for integration into wearable devices. This self-powered breath sensor enabling continuous monitoring of lung cancer symptoms and facilitating compliance checks with legal alcohol consumption limits.
MeSH term(s)	Humans ; Exhalation/physiology ; Humidity ; Ethanol ; Respiration ; Respiratory System
Chemical Substances	Ethanol (3K9958V90M)
Language	English
Publishing date	2024-01-18
Publishing country	England
Document type	Journal Article
ZDB-ID	2615211-3
ISSN	2045-2322 ; 2045-2322
ISSN (online)	2045-2322
ISSN	2045-2322
DOI	10.1038/s41598-024-51862-6
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Article ; Online: Years of life lost (YLL) associated with COVID-19 deaths in Khorasan-RAZAVI province, Iran.

Yousefi, Mehdi / Fazaeli, Somayeh / Mohammad-Pour, Saeed

Journal of public health (Oxford, England)

2021 Volume 45, Issue 1, Page(s) 259–266

Abstract: Background: The number of deaths among people with coronavirus disease 2019 (COVID-19) does not show the true impact of the disease on communities. Therefore, this study aimed to calculate years of life lost (YLL) due to premature death in patients with ...

Abstract	Background: The number of deaths among people with coronavirus disease 2019 (COVID-19) does not show the true impact of the disease on communities. Therefore, this study aimed to calculate years of life lost (YLL) due to premature death in patients with COVID-19. Methods: We performed a descriptive cross-sectional study based on data from one of the largest provinces of Iran, in the period 13 February 2020 to 17 May 2021. We used WHO proposed guidelines for the calculation of the burden of diseases to calculate the YLL among patients with COVID-19, taking into consideration gender in different age groups. Results: Findings showed that 13 628 deaths were due to COVID-19 with associated 249 309 YLL. The study reported higher mortality among men (1222 cases) in the age group over 85 years than in women (840) of the same age group. The minimum number of YLL for men was 1749 in the 5-9 years age group and that for women was 1551 years in the 14-10 years age group. Conclusion: The high number of deaths due to COVID-19 has led to high YLL due to premature death. The provision of adequate health care and appropriate policies will bring about a decrease in YLL due to COVID-19.
MeSH term(s)	Male ; Humans ; Female ; Aged, 80 and over ; Life Expectancy ; Iran/epidemiology ; Cross-Sectional Studies ; COVID-19 ; Mortality, Premature
Language	English
Publishing date	2021-12-12
Publishing country	England
Document type	Journal Article
ZDB-ID	2142082-8
ISSN	1741-3850 ; 1741-3842
ISSN (online)	1741-3850
ISSN	1741-3842
DOI	10.1093/pubmed/fdab392
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Article ; Online: Non-coding RNAs in Precursor Lesions of Colorectal Cancer: Their Role in Cancer Initiation and Formation.

Mohammadpour, Somayeh / Naderi Noukabadi, Fatemeh / Torshizi Esfahani, Amir / Kazemi, Fatemeh / Esmaeili, Sahar / Zafarjafarzadeh, Nikta / Sarpash, SeyedKasra / Nazemalhosseini-Mojarad, Ehsan

Current molecular medicine

2023

Abstract: Colorectal cancer (CRC) is one of the world's most common types of malignancy. The proliferation of precancerous lesions causes this type of cancer. Two distinct pathways for CRC carcinogenesis have been identified: the conventional adenoma-carcinoma ... ...

Abstract	Colorectal cancer (CRC) is one of the world's most common types of malignancy. The proliferation of precancerous lesions causes this type of cancer. Two distinct pathways for CRC carcinogenesis have been identified: the conventional adenoma-carcinoma pathway and the serrated neoplasia pathway. Recently, evidence has demonstrated the regulatory roles of noncoding RNAs (ncRNAs) in the initiation and progression of precancerous lesions, especially in the adenoma-carcinoma pathway and serrated neoplasia pathway. By expanding the science of molecular genetics and bioinformatics, several studies have identified dysregulated ncRNAs that function as oncogenes or tumor suppressors in cancer initiation and formation by diverse mechanisms via intracellular signaling pathways known to act on tumor cells. However, many of their roles are still unclear. This review summarizes the functions and mechanisms of ncRNAs (such as long non-coding RNAs, microRNAs, long intergenic non-coding RNAs, small interfering RNAs, and circRNAs) in the initiation and formation of precancerous lesions.
Language	English
Publishing date	2023-05-23
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	2064873-X
ISSN	1875-5666 ; 1566-5240
ISSN (online)	1875-5666
ISSN	1566-5240
DOI	10.2174/1566524023666230523155719
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Article ; Online: Enhancement of self-powered humidity sensing of graphene oxide-based triboelectric nanogenerators by addition of graphene oxide nanoribbons.

Ejehi, Faezeh / Mohammadpour, Raheleh / Asadian, Elham / Fardindoost, Somayeh / Sasanpour, Pezhman

Mikrochimica acta

2021 Volume 188, Issue 8, Page(s) 251

Abstract: A triboelectric nanogenerator (TENG) electrode sensitive to the adsorption of water molecules has been introduced to create a self-powered humidity sensor. Graphene oxide (GO) nanosheets and graphene oxide nanoribbon (GONR) possessing oxygenated ... ...

Abstract	A triboelectric nanogenerator (TENG) electrode sensitive to the adsorption of water molecules has been introduced to create a self-powered humidity sensor. Graphene oxide (GO) nanosheets and graphene oxide nanoribbon (GONR) possessing oxygenated functional groups, as well as high dielectric constants, have been proposed as appropriate candidates for this purpose. GO papers have been fabricated in three forms, i.e. pure GO paper, uniform composites of GONR and GO, and double-layer structures of GONR on top of GO. Results showed that all of the prepared paper-based TENGs revealed excellent performances by maximum output voltage above 300 V. As active humidity sensors, the maximum voltage response values of 57%, 124%, and 78% were obtained for GO, GONR+GO, and GONR/GO TENGs, respectively. Besides high sensitivity and precision of all variants, GO+GONR TENG demonstrated a rapid response/recovery behavior (0.3/0.5 s). This phenomenon can be attributed to the higher oxygenated groups and defects on the edges of GONR, which leads to facilitating the bulk diffusion of water molecules. Our results open new avenues of GONR application as an additive to enhance the performance of self-powered humidity sensors, as well as conventional hygrometers.
Language	English
Publishing date	2021-07-13
Publishing country	Austria
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	89-9
ISSN	1436-5073 ; 0026-3672
ISSN (online)	1436-5073
ISSN	0026-3672
DOI	10.1007/s00604-021-04921-y
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Article ; Online: Evaluation of the effects of diabetes self-management education based on 5A model on the quality of life and blood glucose of women with gestational diabetes mellitus: an experimental study in eastern Iran.

Rokni, Somayeh / Rezaei, Zahed / Noghabi, Ali Delshad / Sajjadi, Moosa / Mohammadpour, Ali

Journal of preventive medicine and hygiene

2022 Volume 63, Issue 3, Page(s) E442–E447

Abstract: Introduction: Gestational diabetes mellitus (GDM) is an important condition during pregnancy. The aim of the current study was to evaluate the effects of self-management education based on 5A model on the quality of life and blood glucose level of women ...

Abstract	Introduction: Gestational diabetes mellitus (GDM) is an important condition during pregnancy. The aim of the current study was to evaluate the effects of self-management education based on 5A model on the quality of life and blood glucose level of women with GDM. Methods: This quasi-experimental study was conducted on 54 pregnant women referred to the urban health care centers affiliated to the Gonabad University of Medical Sciences from March 2019 to March 2020 based on purposive sampling method. Participants were randomly allocated into intervention and control groups based on stratified random sampling using permuted block randomization method. The intervention group received self-management education program based on 5A model in five sessions during two months. Demographic data, blood glucose level, and diabetes quality of life (DQOL) questionnaire were collected for each participant. Data analysis was performed using the SPSS software version 16 and the level of statistical significance was set at 0.05. Results: Mean age of the participants was 33.11 ± 5.35 years old. At the end of the intervention, the mean blood glucose level of the participants in the intervention group was significantly lower compared to the control group (p < 0.001). The quality of life in the intervention group was significantly improved at the end of the intervention compared to the control group (p < 0.001). Conclusions: Self-management education based on 5A model can effectively improve quality of life and blood glucose levels in women with GDM.
MeSH term(s)	Female ; Humans ; Pregnancy ; Adult ; Diabetes, Gestational/therapy ; Blood Glucose ; Quality of Life ; Iran ; Self-Management
Chemical Substances	Blood Glucose
Language	English
Publishing date	2022-10-27
Publishing country	Italy
Document type	Randomized Controlled Trial ; Journal Article
ZDB-ID	1102926-2
ISSN	2421-4248 ; 1121-2233
ISSN (online)	2421-4248
ISSN	1121-2233
DOI	10.15167/2421-4248/jpmh2022.63.3.2611
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Article ; Online: EMAST frequency in colorectal cancer: a meta-analysis and literature review.

Ranjbar, Reza / Esfahani, Amir T / Nazemalhosseini-Mojarad, Ehsan / Olfatifar, Meysam / Aghdaei, Hamid A / Mohammadpour, Somayeh

Biomarkers in medicine

2020 Volume 14, Issue 11, Page(s) 1021–1030

Abstract: Aim: ...

Abstract	Aim:
MeSH term(s)	Colorectal Neoplasms/diagnosis ; Colorectal Neoplasms/genetics ; Humans ; Microsatellite Instability ; Microsatellite Repeats/genetics
Language	English
Publishing date	2020-09-16
Publishing country	England
Document type	Journal Article ; Meta-Analysis ; Research Support, Non-U.S. Gov't ; Systematic Review
ZDB-ID	2481014-9
ISSN	1752-0371 ; 1752-0363
ISSN (online)	1752-0371
ISSN	1752-0363
DOI	10.2217/bmm-2020-0068
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Article ; Online: Green synthesis, characterization, and application of Fe3O4 nanoparticles for methylene blue removal: RSM optimization, kinetic, isothermal studies, and molecular simulation

Mohammadpour, Amin / Karami, Najmeh / Zabihi, Reza / Fazeliyan, Ebrahim / Abbasi, Alireza / Karimi, Somayeh / Barbosa de Farias, Marina / Adeodato Vieira, Melissa Gurgel / Shahsavani, Ebrahim / Mousavi Khaneghah, Amin

Environmental Research. 2023 May, v. 225 p.115507-

2023

Abstract: Methylene Blue (MB) is a cationic dye causing various health problems such as asthma, heartbeat, eye and skin irritation, nausea, and distress during prolonged exposure. In this regard, the green magnetite nanoparticle was synthesized using the extract ... ...

Abstract	Methylene Blue (MB) is a cationic dye causing various health problems such as asthma, heartbeat, eye and skin irritation, nausea, and distress during prolonged exposure. In this regard, the green magnetite nanoparticle was synthesized using the extract of Prosopis farcta. The synthesized Fe₃O₄nanoparticle was characterized by X-ray powder diffraction (XRD), Field emission scanning electron microscopy (FESEM), energy-dispersive X-ray spectroscopy (EDX), transmission electron microscopy (TEM), Fourier transforms Infrared spectroscopy (FTIR), vibrating sample magnetometer (VSM), and Brunauer-Emmett-Teller (BET). The corresponding parameters, including the primary concentration of MB (5–65 mg/L), the dose of synthesized nanoparticle (0.025–0.925 g/L), solution pH (3–11), and contact time (20–60 min), were considered. Also, central composite design (CCD), as one of the response surface methodologies (RSM), was used for the related modelling and optimization. The particle size of the adsorbent was between 5 and 70 nm, and the nanoparticle has 206.75 m²/g of a specific surface, 6.1 nm of average pore size, and 0.3188 cm³/g of the total pore volume. The optimal conditions for MB removal by the nanoparticle were found to follow an initial MB concentration of 20 mg/L, 0.7 g/L of the nanoparticle dose, pH = 9, and a contact time of 50 min. The pseudo-second-order (PSO) and Freundlich models were the best kinetic and isothermal models for MB removal by the synthesized nanoparticle. Molecular modelling was used to optimize the MB molecular configuration and compute HOMO-LUMO energies, quantum-chemical descriptors, and molecular electrostatic potential to evaluate the nature reactivity of the MB molecule.
Keywords	Prosopis farcta ; X-ray diffraction ; adsorbents ; asthma ; distress ; energy-dispersive X-ray analysis ; eyes ; heart rate ; magnetite ; methylene blue ; molecular conformation ; molecular dynamics ; nanoparticles ; nausea ; pH ; particle size ; porosity ; research ; skin irritation ; transmission electron microscopy ; Adsorption ; Nanoparticle ; Green synthesis ; Iron oxide
Language	English
Dates of publication	2023-05
Publishing place	Elsevier Inc.
Document type	Article ; Online
ZDB-ID	205699-9
ISSN	1096-0953 ; 0013-9351
ISSN (online)	1096-0953
ISSN	0013-9351
DOI	10.1016/j.envres.2023.115507
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Green synthesis, characterization, and application of Fe

Environmental research

2023 Volume 225, Page(s) 115507

Abstract	Methylene Blue (MB) is a cationic dye causing various health problems such as asthma, heartbeat, eye and skin irritation, nausea, and distress during prolonged exposure. In this regard, the green magnetite nanoparticle was synthesized using the extract of Prosopis farcta. The synthesized Fe
MeSH term(s)	Methylene Blue/chemistry ; Adsorption ; Nanoparticles/chemistry ; Microscopy, Electron, Scanning ; Kinetics ; Water Pollutants, Chemical/chemistry ; Spectroscopy, Fourier Transform Infrared
Chemical Substances	Methylene Blue (T42P99266K) ; Water Pollutants, Chemical
Language	English
Publishing date	2023-02-23
Publishing country	Netherlands
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	205699-9
ISSN	1096-0953 ; 0013-9351
ISSN (online)	1096-0953
ISSN	0013-9351
DOI	10.1016/j.envres.2023.115507
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Article: Is gastric mapping needed in the endoscopy of dyspeptic patients?

Valizadeh Toosi, Seyed Mohammad / Sanayifar, Seyede Fateme / Mohammadpour, Reza Ali / Sheidaei, Somayeh

Gastroenterology and hepatology from bed to bench

2021 Volume 14, Issue 1, Page(s) 31–35

Abstract: Aim: Our study aimed to determine the prevalence of intestinal metaplasia in dyspeptic patients who underwent upper GI endoscopy.: Background: Intestinal metaplasia, which is defined as the replacement of normal gastric mucosa by metaplastic ... ...

Abstract	Aim: Our study aimed to determine the prevalence of intestinal metaplasia in dyspeptic patients who underwent upper GI endoscopy. Background: Intestinal metaplasia, which is defined as the replacement of normal gastric mucosa by metaplastic intestinal epithelium, has been described as a premalignant gastric lesion. Methods: Six hundred two consecutive patients with dyspeptic symptoms who had undergone upper GI endoscopy were included in the study. For all patients, gastric mapping was performed to determine the presence of intestinal metaplasia. All histologic samples were reported according to the updated Sydney classification. Results: Total of 61.3% of the patients were female. The mean age of the patients was 46±15 years. The overall prevalence of intestinal metaplasia was 22%. The distribution of intestinal metaplasia in the stomach was 15.1% in the antrum, 4.3% in the body, and 2.6% in the antrum and body together. Also, the prevalence of intestinal metaplasia in the age group of under 40 years was 9.5% and in patients over 40 years it was 29.5%.. Conclusion: The results of this study have shown that more than one-fifth of the patients with dyspepsia have intestinal metaplasia. This indicates that gastric mapping in patients with dyspepsia may lead to the detection of precancerous lesions especially after the age of 40.
Language	English
Publishing date	2021-02-16
Publishing country	Iran
Document type	Journal Article
ZDB-ID	2569124-7
ISSN	2008-4234 ; 2008-2258
ISSN (online)	2008-4234
ISSN	2008-2258
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Article: High expression of

Mohammadpour, Somayeh / Esfahani, Amir Torshizi / Khorasaniasl, Seyyedmohammadamin / Karimpour, Raana / Bakhshian, Farbod / Moradi, Afshin / Nazemalhosseini-Mojarad, Ehsan

The Indian journal of medical research

2022 Volume 156, Issue 1, Page(s) 64–69

Abstract: Background & objectives: Transforming growth factor-beta (TGF-β) signalling pathway has been reported to be involved in metastasis and at the same time has been considered compellingly an important mediator of epithelial-to-mesenchymal transition (EMT). ...

Abstract	Background & objectives: Transforming growth factor-beta (TGF-β) signalling pathway has been reported to be involved in metastasis and at the same time has been considered compellingly an important mediator of epithelial-to-mesenchymal transition (EMT). Besides, EMT process is maintained by zinc-finger E-box-binding homeobox 1 (ZEB1) gene which is induced by TGF-β pathway. TGF-β has been shown to be associated with elevated microsatellite alterations at selected tetranucleotide repeats (EMAST) phenomenon, which is one of the prognostic biomarkers of colorectal cancer (CRC). This study was conducted to determine the link among ZEB1-induced TGF-β, EMAST status and metastasis. Methods: The expression level of ZEB1 was evaluated using quantitative reverse transcription (qRT) real-time PCR in 122 formalin fixed paraffin-embedded tissues of CRC sample with known EMAST status and TGF-β/Smad-dependent pathways. The association among ZEB1 expression, TGF-β signalling pathway, EMAST status and metastatic behaviour was examined. Results: ZEB1 gene expression level was higher in tumour tissues as compared to normal samples (P<0.045). In addition, ZEB1 positive expression level was associated significantly with metastasis (P=0.05), EMAST Interpretation & conclusions: Our results validated significant association between activated TGF-β signalling pathway and EMAST
MeSH term(s)	Humans ; Cell Line, Tumor ; Colorectal Neoplasms/genetics ; Colorectal Neoplasms/pathology ; Epithelial-Mesenchymal Transition ; Microsatellite Repeats/genetics ; Neoplasm Metastasis ; Transforming Growth Factor beta/metabolism ; Zinc Finger E-box-Binding Homeobox 1/genetics ; Zinc Finger E-box-Binding Homeobox 1/metabolism
Chemical Substances	Transforming Growth Factor beta ; ZEB1 protein, human ; Zinc Finger E-box-Binding Homeobox 1
Language	English
Publishing date	2022-12-20
Publishing country	India
Document type	Journal Article
ZDB-ID	390883-5
ISSN	0971-5916 ; 0019-5340
ISSN	0971-5916 ; 0019-5340
DOI	10.4103/ijmr.IJMR_1062_20
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