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Article: Anaesthetic considerations during video-assisted thoracoscopic excision of a mediastinal ectopic parathyroid adenoma.

Sarma, Riniki / Gupta, Raghav / Kumar, Vinod / Pandit, Anuja

2021 Volume 65, Issue 6, Page(s) 492–494

Language	English
Publishing date	2021-06-22
Publishing country	India
Document type	Journal Article
ZDB-ID	412570-8
ISSN	0019-5049
ISSN	0019-5049
DOI	10.4103/ija.IJA_1523_20
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Article: Absent Lung Deflation Because of Blockade Using an Endobronchial Blocker.

Garg, Rakesh / Pandit, Anuja

Turkish journal of anaesthesiology and reanimation

2017 Volume 45, Issue 3, Page(s) 172–173

Abstract: One-lung ventilation is required for various thoracic procedures. In addition, various strategies such as the use of double-lumen tube, uninvent tubes, and endobronchial blocker have been used for performing one-lung ventilation. Each of these techniques ...

Abstract	One-lung ventilation is required for various thoracic procedures. In addition, various strategies such as the use of double-lumen tube, uninvent tubes, and endobronchial blocker have been used for performing one-lung ventilation. Each of these techniques has its advantages and limitations. Certain factors for failure of endobronchial blocker to provide lung deflation has been described in literature. We report a different aetiology of failure of lung deflation, although the endobronchial blocker was appropriately placed.
Language	English
Publishing date	2017-02-01
Publishing country	Turkey
Document type	Case Reports
ISSN	2667-677X
ISSN	2667-677X
DOI	10.5152/TJAR.2017.60566
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Article: A Correlation Analysis of Peripheral Oxygen Saturation and Arterial Oxygen Saturation Among COVID-19 Patients.

Sirohiya, Prashant / Vig, Saurabh / Pandey, Khushboo / Meena, Jitendra K / Singh, Ram / Ratre, Brajesh K / Kumar, Balbir / Pandit, Anuja / Bhatnagar, Sushma

Cureus

2022 Volume 14, Issue 4, Page(s) e24005

Abstract: Background and objective It has been observed that peripheral oxygen saturation ( ... ...

Abstract	Background and objective It has been observed that peripheral oxygen saturation (SpO
Language	English
Publishing date	2022-04-10
Publishing country	United States
Document type	Journal Article
ZDB-ID	2747273-5
ISSN	2168-8184
ISSN	2168-8184
DOI	10.7759/cureus.24005
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Article: Effect of Meditation and Breathing Exercises on the Well-being of Patients with SARS-CoV-2 Infection under Institutional Isolation: A Randomized Control Trial.

Mahendru, Kiran / Pandit, Anuja / Singh, Vishwajeet / Choudhary, Nandan / Mohan, Anant / Bhatnagar, Sushma

Indian journal of palliative care

2021 Volume 27, Issue 4, Page(s) 490–494

Abstract: Objectives: The corona virus disease-19 (COVID-19) pandemic has affected every domain of human health be it physical or mental. The uncertainty of disease progression in patients with SARS-CoV-2 infection can lead to major psychological and psychiatric ... ...

Abstract	Objectives: The corona virus disease-19 (COVID-19) pandemic has affected every domain of human health be it physical or mental. The uncertainty of disease progression in patients with SARS-CoV-2 infection can lead to major psychological and psychiatric concerns that should not be overlooked. The interventions should be directed to the vulnerable population to help them mitigate the stress and anxiety caused by the infection and isolation. We evaluated the effect of meditation and breathing exercises on the well-being of patients with SARS-CoV-2 infection under institutional isolation. Materials and methods: We conducted a randomized control trial on 84 subjects, 18 years and above, asymptomatic, or mildly symptomatic SARS-CoV-2 infected patients under institutional isolation. Subjects were randomly and equally divided into a control group and interventional group. We measured the depression, anxiety, and stress levels as well as quality of sleep in patients after 7 days of meditation and breathing exercises in the intervention group versus standard care in the control group. Results: Meditation and breathing exercises had a statistically significant effect on the depression level (P < 0.001), stress level (P = 0.004), and the quality of sleep [trouble falling asleep (P = 0.007), trouble staying asleep (P = 0.004), and feel tired after waking up in the morning (P = 0.003)]. Further, the positive effect of intervention on the level of anxiety in patients under isolation was also observed; however, the difference was not found to be statistically significant (P = 0.528). Conclusion: Meditation and breathing exercises have positive effects on depression, stress levels, and quality of sleep in COVID-19 positive patients under strict institutional isolation.
Language	English
Publishing date	2021-11-26
Publishing country	United States
Document type	Journal Article
ISSN	0973-1075
ISSN	0973-1075
DOI	10.25259/IJPC_40_21
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Article ; Online: Corrigendum to "Efficacy and safety of pegylated interferon alfa-2b in moderate COVID-19: A phase II, randomized, controlled, open-label study" [International Journal of Infectious Diseases, Volume 105, April 2021, Pages 516-521].

Pandit, Anuja / Bhalani, Nirav / Bhushan, B L Shashi / Koradia, Parshottam / Gargiya, Shweta / Bhomia, Vinay / Kansagra, Kevinkumar

International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases

2021 Volume 109, Page(s) 322

Language	English
Publishing date	2021-06-28
Publishing country	Canada
Document type	Published Erratum
ZDB-ID	1331197-9
ISSN	1878-3511 ; 1201-9712
ISSN (online)	1878-3511
ISSN	1201-9712
DOI	10.1016/j.ijid.2021.06.030
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Article ; Online: No Doppler Single Position-Lateral Intercostal Artery Perforator Flap (NDSP-LICAP): a Safe and Versatile Flap for Breast Oncoplasty in Resource-Limited Setting.

Mishra, Ashutosh / Deo, S V S / Oberoi, Ajit Singh / Gowda, Manoj / Bhoriwal, Sandeep Kumar / Saikia, Jyotishman / Pandit, Anuja / Mallick, Supriya / Batra, Atul / Jha, Akash

World journal of surgery

2023 Volume 47, Issue 11, Page(s) 2753–2760

Abstract: Introduction: The lateral intercostal artery perforator flap (LICAP) has emerged as one of the safest and less morbid flaps for lateral and central breast defects. We hereby describe a reproducible no Doppler single position (NDSP) technique to harvest ... ...

Abstract	Introduction: The lateral intercostal artery perforator flap (LICAP) has emerged as one of the safest and less morbid flaps for lateral and central breast defects. We hereby describe a reproducible no Doppler single position (NDSP) technique to harvest it in single position without handheld Doppler, making it a versatile flap for lateral breast defects in resource-limited setting also. Materials and methods: With this technique, we performed a total of 22 LICAP turnover flaps over a period of 18 months from January 2020 to June 2021. In all 22 cases, the indication of flap was to fill the post-breast conservation surgery (BCS) defects in outer quadrant of breast. All LICAP flaps were harvested by surface marking of anatomical landmarks and without handheld Doppler. Results: Out of 22 LICAP turnover flaps, thirteen were harvested for left breast and nine for right breast. The median width and length of the flap were 12.2 cm and 19.6 cm, respectively. The additional mean operative time was 41 min. All LICAP flaps survived well, and grade 1 Clavien-Dindo morbidity was documented in four cases. Mean hospital stay was 2.6 days. All patients received radiotherapy on their stipulated schedule. Early cosmetic outcome was good, and long-term outcomes are awaited. Conclusion: NDSP-LICAP flap is a workhorse for lateral breast defects. Precise knowledge of perforators and anatomical landmarks can be used for harvesting these flaps, thus avoiding ultrasound Doppler and dedicated training for perforator localization. This technique has short learning curve without the need for any plastic surgery training. The early cosmetic outcomes are good.
MeSH term(s)	Humans ; Perforator Flap/blood supply ; Resource-Limited Settings ; Plastic Surgery Procedures ; Breast ; Arteries
Language	English
Publishing date	2023-08-13
Publishing country	United States
Document type	Journal Article
ZDB-ID	224043-9
ISSN	1432-2323 ; 0364-2313
ISSN (online)	1432-2323
ISSN	0364-2313
DOI	10.1007/s00268-023-07126-x
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Zs.A 1336: Show issues

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Article ; Online: Hypercalcemia due to methadone-induced adrenal insufficiency in a case of oral cancer.

Sharma, Ankit / Subhash, Mahajan Jitendra / Pandit, Anuja / Bhan, Swati / Bhatnagar, Sushma

Palliative & supportive care

2020 Volume 18, Issue 6, Page(s) 751–753

Abstract: A 31-year-old patient of post-surgical recurrent buccal carcinoma (post-chemo and radiotherapy) on multimodal analgesia with methadone, paracetamol and gabapentin presented to pain clinic with occasional bleeding from tumor area and incidental ... ...

Abstract	A 31-year-old patient of post-surgical recurrent buccal carcinoma (post-chemo and radiotherapy) on multimodal analgesia with methadone, paracetamol and gabapentin presented to pain clinic with occasional bleeding from tumor area and incidental hypercalcemia. The hypercalcemia was attributed to adrenal insufficiency due to methadone, with no other obvious reasons identified for hypercalcemia or adrenal insufficiency. The patient was managed with the change of opioid, regular aseptic wound dressings and management of hypercalcemia with hydration, calcitonin and steroid therapy. Hypercalcemia in a cancer patient can have multiple other causes like hypercalcemia of malignancy and primary or secondary parathyroid carcinoma. A strong clinical suspicion and appropriate battery of tests may be required to arrive at the diagnosis. Prompt management, including identification and management of the primary pathology along with aggressive hydration with hormonal therapy, may prove to be life-saving.
MeSH term(s)	Adrenal Insufficiency/etiology ; Adrenal Insufficiency/physiopathology ; Adult ; Humans ; Hypercalcemia/etiology ; Hypercalcemia/physiopathology ; Male ; Methadone/adverse effects ; Methadone/therapeutic use ; Mouth Neoplasms/drug therapy ; Mouth Neoplasms/physiopathology ; Pain Management/methods
Chemical Substances	Methadone (UC6VBE7V1Z)
Language	English
Publishing date	2020-10-29
Publishing country	England
Document type	Case Reports ; Journal Article
ZDB-ID	2454009-2
ISSN	1478-9523 ; 1478-9515
ISSN (online)	1478-9523
ISSN	1478-9515
DOI	10.1017/S1478951520001133
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Article: A pilot randomised clinical trial comparing desflurane anaesthesia vs total intravenous anaesthesia, for changes in haemodynamic, inflammatory and coagulation parameters in patients undergoing hyperthermic intraperitoneal chemotherapy.

Pandit, Anuja / Singh, Vishwajeet / Bharati, Sachidanand J / Mishra, Seema / Deo, Suryanarayana Vs / Bhatnagar, Sushma

Indian journal of anaesthesia

2020 Volume 64, Issue 8, Page(s) 688–695

Abstract: Background and aims: Cytoreduction and hyperthermic intraperitoneal chemotherapy (CRS+HIPEC) cause numerous pathophysiological changes. The objective of this study was to compare the effect of two anaesthetic techniques on haemodynamic changes, ... ...

Abstract	Background and aims: Cytoreduction and hyperthermic intraperitoneal chemotherapy (CRS+HIPEC) cause numerous pathophysiological changes. The objective of this study was to compare the effect of two anaesthetic techniques on haemodynamic changes, inflammatory and coagulation parameters during this procedure. Methods: Twenty-one consenting adults undergoing CRS+HIPEC procedure, were block randomised to receive desflurane (V, Results: Changes in core body temperature and haemodynamic variables during the hyperthermic intraperitoneal chemotherapy (HIPEC) phase were comparable between the two groups; except mean variance of mean arterial pressure, which was significantly higher ( Conclusion: Desflurane group suffered greater mean arterial pressure (MAP) instability during the HIPEC phase. Inflammation in both groups was highest during the first 24 h after surgery. Prolonged inflammation was noted in patients receiving desflurane.
Language	English
Publishing date	2020-07-31
Publishing country	India
Document type	Journal Article
ZDB-ID	412570-8
ISSN	0019-5049
ISSN	0019-5049
DOI	10.4103/ija.IJA_34_20
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Article ; Online: Efficacy and safety of pegylated interferon alfa-2b in moderate COVID-19: A phase II, randomized, controlled, open-label study.

Pandit, Anuja / Bhalani, Nirav / Bhushan, B L Shashi / Koradia, Parshottam / Gargiya, Shweta / Bhomia, Vinay / Kansagra, Kevinkumar

International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases

2021 Volume 105, Page(s) 516–521

Abstract: Objective: To evaluate the efficacy and safety of pegylated interferon alfa-2b (PEG IFN-α2b) along with the standard of care (SOC) in subjects with moderate COVID-19.: Methods: In this phase 2, randomized, open-label study, adult subjects aged ≥18 ... ...

Abstract	Objective: To evaluate the efficacy and safety of pegylated interferon alfa-2b (PEG IFN-α2b) along with the standard of care (SOC) in subjects with moderate COVID-19. Methods: In this phase 2, randomized, open-label study, adult subjects aged ≥18 years with RT-PCR confirmed COVID-19 with moderate symptoms were randomized in a 1:1 to receive PEG IFN-α2b plus SOC, or SOC alone. The primary endpoint was improvement in clinical status on day 15, measured by the WHO 7-point ordinal scale. Results: Forty subjects were randomized to PEG IFN-α2b plus SOC (n = 20) and SOC (n = 20). Overall, 19 (95.00%) subjects in PEG IFN-α2b plus SOC had achieved clinical improvement on day 15 compared to 13 (68.42%) subjects in SOC (p < 0.05). Overall, 80% and 95% of subjects in the PEG IFN-α2b plus SOC group had a negative RT-PCR result on day 7 and day 14, respectively, compared to 63% and 68% in the SOC group. Adverse events (AEs) were reported for eleven subjects in the PEG IFN-α2b plus SOC group and eight subjects in the SOC group. All reported AEs were mild. Conclusion: The significant improvement in clinical status on day 15 is likely due to faster viral reduction compared to SOC with the PEG IFN-α2b treated moderate COVID-19 subjects showing a difference as early as day seven and becoming significant by day 14.
MeSH term(s)	Adult ; Aged ; Antiviral Agents/therapeutic use ; COVID-19/drug therapy ; Female ; Humans ; Interferon alpha-2/adverse effects ; Interferon alpha-2/therapeutic use ; Interferon-alpha/adverse effects ; Interferon-alpha/therapeutic use ; Male ; Middle Aged ; Polyethylene Glycols/adverse effects ; Polyethylene Glycols/therapeutic use ; Recombinant Proteins/adverse effects ; Recombinant Proteins/therapeutic use ; SARS-CoV-2
Chemical Substances	Antiviral Agents ; Interferon alpha-2 ; Interferon-alpha ; Recombinant Proteins ; Polyethylene Glycols (3WJQ0SDW1A) ; peginterferon alfa-2b (G8RGG88B68)
Language	English
Publishing date	2021-03-10
Publishing country	Canada
Document type	Clinical Trial, Phase II ; Journal Article ; Multicenter Study ; Randomized Controlled Trial
ZDB-ID	1331197-9
ISSN	1878-3511 ; 1201-9712
ISSN (online)	1878-3511
ISSN	1201-9712
DOI	10.1016/j.ijid.2021.03.015
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Article: The incidence of anosmia in patients with laboratory-confirmed COVID 19 infection in India: An observational study.

Kumar, Vinod / Singla, Sapna / Gupta, Nishkarsh / Bharati, Sachidanand Jee / Garg, Rakesh / Pandit, Anuja / Vig, Saurabh / Mishra, Seema / Bhatnagar, Sushma

Journal of anaesthesiology, clinical pharmacology

2021 Volume 37, Issue 1, Page(s) 51–56

Abstract: Background and aims: Acute loss of smell or anosmia is a common and sometimes the only symptom observed in patients with coronavirus disease-2019 (COVID-19). The objective of the study was to determine the prevalence, time of onset, and duration of ... ...

Abstract	Background and aims: Acute loss of smell or anosmia is a common and sometimes the only symptom observed in patients with coronavirus disease-2019 (COVID-19). The objective of the study was to determine the prevalence, time of onset, and duration of anosmia in patients with COVID-19 infection and the association of anosmia with other symptoms and eosinophil count. Material and methods: Two hundred patients with laboratory-confirmed COVID-19 infection, who were asymptomatic or mildly symptomatic were assessed for olfaction with a nonirritant odor. The presence of anosmia was recorded, and a questionnaire integrating the anosmia reporting tool was filled. Patients with anosmia/hyposmia were followed telephonically at 7 and 14 days for resolution of anosmia and other symptoms. The presence of anosmia was correlated with eosinophil count. Results: Of the 200 COVID-19 patients, 87% were symptomatic. More than half of the patients had fever (56%). Anosmia was observed in 30% of the patients and hyposmia in 4% of patients. In 41% of the patients, olfactory loss was reported before diagnosis. The mean duration of anosmia was 7.8 (± 5) days; 97% of patients recovered with a resolution of symptoms within 2 weeks. Ageusia was the most commonly and significantly associated symptom with anosmia (66%, n = 45) followed by sore throat (41%), and rhinorrhea (28%). The symptoms in both the sexes were comparable. Absolute eosinophil count of <40/μL was observed in 59 patients (29.5%) and an absolute eosinophil count of 0 in 17 patients (8.5%). Among the 68 anosmic patients, 36 (47%) patients had eosinopenia, which was statistically significant. Conclusion: Anosmia is an early and sometimes the only symptom in approximately one-third of the patients with COVID-19 infection. Eosinophil count should be checked in anosomic patient with suspicion of COVID-19 infection. Objective tools for olfactory and gustatory assessment should be brought into practice for early and prompt diagnosis to control the spread of the disease.
Language	English
Publishing date	2021-04-10
Publishing country	India
Document type	Journal Article
ZDB-ID	1401760-x
ISSN	0970-9185
ISSN	0970-9185
DOI	10.4103/joacp.JOACP_653_20
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