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  1. Article ; Online: Brownout: another threat to ICU physicians and nurses.

    Valette, Xavier

    Intensive care medicine

    2018  Volume 44, Issue 5, Page(s) 694

    MeSH term(s) Attitude of Health Personnel ; Intensive Care Units ; Nurses ; Physicians
    Language English
    Publishing date 2018-05-24
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 80387-x
    ISSN 1432-1238 ; 0340-0964 ; 0342-4642 ; 0935-1701
    ISSN (online) 1432-1238
    ISSN 0340-0964 ; 0342-4642 ; 0935-1701
    DOI 10.1007/s00134-018-5164-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1089: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (1.OG)
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  2. Article ; Online: Questioning Tocilizumab Use in Hospitalized Patients With Coronavirus Disease 2019.

    Mombrun, Martin / Valette, Xavier

    Chest

    2021  Volume 159, Issue 5, Page(s) 2115–2116

    MeSH term(s) Antibodies, Monoclonal, Humanized ; COVID-19/drug therapy ; Cytokine Release Syndrome ; Humans ; SARS-CoV-2
    Chemical Substances Antibodies, Monoclonal, Humanized ; tocilizumab (I031V2H011)
    Language English
    Publishing date 2021-04-16
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 1032552-9
    ISSN 1931-3543 ; 0012-3692
    ISSN (online) 1931-3543
    ISSN 0012-3692
    DOI 10.1016/j.chest.2020.11.069
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Ui III Zs.45: Show issues Location:
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    Zs.MO 349: Show issues

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  3. Article ; Online: Anakinra for patients with COVID-19.

    Valette, Xavier / Cheyron, Damien du

    The Lancet Rheumatology

    2020  Volume 2, Issue 7, Page(s) e382

    Keywords covid19
    Language English
    Publishing date 2020-06-25
    Publishing country England
    Document type Journal Article
    ISSN 2665-9913
    ISSN (online) 2665-9913
    DOI 10.1016/S2665-9913(20)30176-4
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  4. Article ; Online: Radiation pneumonitis and chemotherapy in a patient with multiple myeloma.

    Cuchet, Pierre / Valette, Xavier

    Lancet (London, England)

    2021  Volume 397, Issue 10283, Page(s) 1484

    MeSH term(s) Adrenal Cortex Hormones/therapeutic use ; Aged ; Antineoplastic Agents/therapeutic use ; Antineoplastic Combined Chemotherapy Protocols/therapeutic use ; Bortezomib/therapeutic use ; Combined Modality Therapy ; Dyspnea/etiology ; Fever/etiology ; Humans ; Male ; Multiple Myeloma/complications ; Multiple Myeloma/drug therapy ; Radiation Pneumonitis/diagnosis ; Radiation Pneumonitis/drug therapy ; Tomography, X-Ray Computed
    Chemical Substances Adrenal Cortex Hormones ; Antineoplastic Agents ; Bortezomib (69G8BD63PP)
    Language English
    Publishing date 2021-04-17
    Publishing country England
    Document type Case Reports ; Journal Article
    ZDB-ID 3306-6
    ISSN 1474-547X ; 0023-7507 ; 0140-6736
    ISSN (online) 1474-547X
    ISSN 0023-7507 ; 0140-6736
    DOI 10.1016/S0140-6736(21)00315-9
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    Ua VI Zs.5: Show issues Location:
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    Zs.MG 94: Show issues

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  5. Article ; Online: Anakinra for patients with COVID-19

    Valette, Xavier / Cheyron, Damien du

    The Lancet Rheumatology

    2020  Volume 2, Issue 7, Page(s) e382

    Keywords covid19
    Language English
    Publisher Elsevier BV
    Publishing country us
    Document type Article ; Online
    ISSN 2665-9913
    DOI 10.1016/s2665-9913(20)30176-4
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article ; Online: Recirculation in Extracorporeal Membrane Oxygenation: The Warning Comes From the Cannula.

    Descamps, Richard / Mombrun, Martin / Valette, Xavier / Du Cheyron, Damien

    ASAIO journal (American Society for Artificial Internal Organs : 1992)

    2021  Volume 67, Issue 8, Page(s) e132–e133

    MeSH term(s) Cannula ; Extracorporeal Membrane Oxygenation/adverse effects ; Humans ; Oxygen
    Chemical Substances Oxygen (S88TT14065)
    Language English
    Publishing date 2021-02-28
    Publishing country United States
    Document type Journal Article
    ZDB-ID 759982-1
    ISSN 1538-943X ; 0162-1432 ; 1058-2916
    ISSN (online) 1538-943X
    ISSN 0162-1432 ; 1058-2916
    DOI 10.1097/MAT.0000000000001298
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    Uk I Zs.199: Show issues Location:
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    Zs.B 2435: Show issues Location:
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  8. Article ; Online: The authors reply.

    Valette, Xavier / du Cheyron, Damien

    Critical care medicine

    2017  Volume 45, Issue 7, Page(s) e746–e747

    MeSH term(s) Contrast Media ; Kidney
    Chemical Substances Contrast Media
    Language English
    Publishing date 2017-06-16
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 197890-1
    ISSN 1530-0293 ; 0090-3493
    ISSN (online) 1530-0293
    ISSN 0090-3493
    DOI 10.1097/CCM.0000000000002456
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    Zs.A 1261: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
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  9. Article ; Online: Mediastinal lymphadenopathy in patients with severe COVID-19.

    Valette, Xavier / du Cheyron, Damien / Goursaud, Suzanne

    The Lancet. Infectious diseases

    2020  Volume 20, Issue 11, Page(s) 1230

    MeSH term(s) Aged ; Betacoronavirus/genetics ; COVID-19 ; Cohort Studies ; Coronavirus Infections/complications ; Coronavirus Infections/diagnostic imaging ; Coronavirus Infections/epidemiology ; Coronavirus Infections/virology ; France/epidemiology ; Humans ; Intensive Care Units ; Lymph Nodes/diagnostic imaging ; Lymph Nodes/pathology ; Lymphadenopathy/complications ; Lymphadenopathy/diagnostic imaging ; Male ; Mediastinal Diseases/complications ; Mediastinal Diseases/diagnostic imaging ; Mediastinum ; Pandemics ; Pneumonia, Viral/complications ; Pneumonia, Viral/diagnostic imaging ; Pneumonia, Viral/epidemiology ; Pneumonia, Viral/virology ; SARS-CoV-2 ; Severity of Illness Index ; Tomography, X-Ray Computed
    Keywords covid19
    Language English
    Publishing date 2020-04-21
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 2061641-7
    ISSN 1474-4457 ; 1473-3099
    ISSN (online) 1474-4457
    ISSN 1473-3099
    DOI 10.1016/S1473-3099(20)30310-8
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    Zs.A 5743: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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  10. Article ; Online: Treatment patterns and clinical outcomes of extensive stage small cell lung cancer (SCLC) in the real-world evidence ESME cohort before the era of immunotherapy.

    Valette, Clarisse Audigier / Filleron, Thomas / Debieuvre, Didier / Lena, Hervé / Pérol, Maurice / Chouaid, Christos / Simon, Gaëtane / Quantin, Xavier / Girard, Nicolas

    Respiratory medicine and research

    2023  Volume 84, Page(s) 101012

    Abstract: Background: Small cell lung cancer (SCLC) is a highly aggressive entity of lung cancer with tendency toward early recurrence after first-line treatment. As per recently updated European Society for Medical Oncology recommendations, first-line treatment ... ...

    Abstract Background: Small cell lung cancer (SCLC) is a highly aggressive entity of lung cancer with tendency toward early recurrence after first-line treatment. As per recently updated European Society for Medical Oncology recommendations, first-line treatment with up to 4 cycles of platinum-etoposide combined with immune checkpoint inhibitor (ICIs)-targeting PD-L1, is now the standard of care. The purpose of the current analysis is to identify current patient profiles and treatment strategies in real life clinical practice, and report outcomes in Extensive Stage (ES)-SCLC.
    Methods: Non-interventional, retrospective, multicentre, comparative study was carried out to describe the outcome of ES-SCLC patients included in the Epidémiologie Stratégie Médico-Economique (ESME) data platform for advanced and metastatic lung cancer. Patients were selected from 34 health care facilities between January 2015 and December 2017, before the era of immunotherapy.
    Results: 1315 patients were identified, including 64% male and 78% under 70 year-old; 24% had at least 3 metastatic sites, mainly liver metastases (43%), bone metastases (36%), brain metastases (32%). 49% received only one line of systemic treatment; 30% and 21% received 2 and 3 lines or more, respectively. Carboplatin was more frequently used than cisplatin (71% and 29%, respectively). Prophylactic cranial irradiation was infrequent (4% of patients), but 16% of patients received thoracic radiation therapy, mainly after the completion of first-line chemotherapy (72% of patients); such strategies were more frequently applied in cisplatin/etoposide than carboplatin/etoposide patients (p = 0.006 and p = 0.015, respectively). After a median follow-up time of 21.8 (95% CI: 20.9-23.3) months, median real-world Progression-Free Survival (rw-PFS) was 6.2 (95% CI: 5.7; 6.9) and 6.1 (95% CI: 5.8; 6.3) months for cisplatin/etoposide and carboplatin/etoposide doublet regimens, respectively; 24-month rwPFS and Overall Survival were 3.2% (95% CI: 2.3; 4;2) and 22.2% (95% CI: 19.4; 25.1) in the whole population, respectively.
    Conclusion: Our data provide with landmark reference findings on ES-SCLC before the immunotherapy era, and cover many aspects of the treatment strategy, while highlighting on the role of radiotherapy, subsequent lines of therapy, and the outcomes of patients. Generation of real-world data focusing on patients who received platinum-based chemotherapy combined with immune checkpoint inhibitors is under way.
    MeSH term(s) Humans ; Male ; Aged ; Female ; Small Cell Lung Carcinoma/drug therapy ; Lung Neoplasms/drug therapy ; Cisplatin/adverse effects ; Carboplatin/therapeutic use ; Etoposide/adverse effects ; Retrospective Studies ; Immunotherapy
    Chemical Substances Cisplatin (Q20Q21Q62J) ; Carboplatin (BG3F62OND5) ; Etoposide (6PLQ3CP4P3)
    Language English
    Publishing date 2023-03-27
    Publishing country France
    Document type Journal Article
    ISSN 2590-0412
    ISSN (online) 2590-0412
    DOI 10.1016/j.resmer.2023.101012
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