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  1. Article: Pulmonary tuberculosis due to B.C.G.

    Marks, J / Jenkins, P A / Kilpatrick, G S / Engbaek, H C / Vergmann, B

    British medical journal

    1971  Volume 3, Issue 5768, Page(s) 229–230

    MeSH term(s) Adult ; Aminosalicylic Acids/therapeutic use ; Arthritis, Juvenile/complications ; Female ; Humans ; Immune System Diseases ; Isoniazid/therapeutic use ; Mycobacterium Infections/complications ; Mycobacterium Infections/immunology ; Mycobacterium bovis ; Radiography ; Streptomycin/therapeutic use ; Tuberculosis, Pulmonary/complications ; Tuberculosis, Pulmonary/diagnostic imaging ; Tuberculosis, Pulmonary/drug therapy ; Tuberculosis, Pulmonary/etiology ; Tuberculosis, Pulmonary/immunology
    Chemical Substances Aminosalicylic Acids ; Isoniazid (V83O1VOZ8L) ; Streptomycin (Y45QSO73OB)
    Language English
    Publishing date 1971-07-24
    Publishing country England
    Document type Journal Article
    ZDB-ID 80088-0
    ISSN 0007-1447 ; 0267-0623 ; 0959-8138 ; 0959-8146
    ISSN 0007-1447 ; 0267-0623 ; 0959-8138 ; 0959-8146
    DOI 10.1136/bmj.3.5768.229
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    In stock of ZB MED Cologne/Königswinter

    Ua VI Zs.10: Show issues Location:
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  2. Article: E.C.G. abnormalities in steroid-treated rheumatoid patients.

    Stewart, I M / Marks, J S

    Lancet (London, England)

    1977  Volume 2, Issue 8050, Page(s) 1237–1238

    MeSH term(s) Arthritis, Rheumatoid/drug therapy ; Electrocardiography ; Heart Diseases/chemically induced ; Humans ; Prednisolone/adverse effects ; Prednisolone/therapeutic use
    Chemical Substances Prednisolone (9PHQ9Y1OLM)
    Language English
    Publishing date 1977-12-10
    Publishing country England
    Document type Letter
    ZDB-ID 3306-6
    ISSN 1474-547X ; 0140-6736 ; 0023-7507
    ISSN (online) 1474-547X
    ISSN 0140-6736 ; 0023-7507
    DOI 10.1016/s0140-6736(77)90486-x
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    In stock of ZB MED Cologne/Königswinter

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    Zs.MG 94: Show issues

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  3. Article ; Online: Bubble mediated polymerization of RNA and DNA

    Roman Marks

    AIMS Biophysics, Vol 9, Iss 2, Pp 96-

    2022  Volume 107

    Abstract: ... and revolutions may conduct winding of hexagonal blocks found in nitrogenous bases A, G and C, T or U ... as well as pentagonal rings in nitrogenous bases A and G are being winded. The compensative anionic flow ...

    Abstract Research dedicated to trace rotational motion of bubbles in saline water revealed that these may generate either single cationic or cationic/anionic motions, including spliced double helix flow. In all cases, the aggregated ionic flows propagate in spiraling as well as rotational manner. However, if bi-ionic or double helix motion is generated, the flow is oppositely directed and has opposite electric charges. Next, the assembled flow is forced to pirouette within the bubble vortex. During that processing the narrowing of spiraling flow takes place and result in increase of revolutions to even millions per second. As a result, a significant friction is induced between revolving ionic hydrates allowing continuous detachment of electrons from covalent atomic shells of electropositive elements. Then, free electrons may be attracted by electronegative elements that are dissolved in seawater. Afterwards, that negatively charged elements may undergo electrical condensation around cationic centers of revolutions. That explain a unique mechanism which operates when negatively charged phosphate compounds and pentagonal blocks found in RNA and DNA as ribose as well as pentagonal rings in nitrogenous bases A and G are being winded. The compensative anionic flow and revolutions may conduct winding of hexagonal blocks found in nitrogenous bases A, G and C, T or U. These assume to gather more positive charge needed to bridge negatively charged sugar molecules in nucleic acids. Thus, the continuity in generation of electronegative compounds and spiral manner of arranging them within the sub-bubble vortices should be regarded as a mechanism responsible for precise, rotational-electric polymerization of elongated macromolecules of RNA/DNA architecture. Reported research refers mainly to physical processes activated by rising bubbles thus should be confronted with other experimental methods used in genetics, microbiology and chemistry.
    Keywords bubbles in seawater ; aggregation of ions ; friction between revolving ions ; generation of electronegative compounds ; synthesis of ringed molecules ; assemblage of rna/dna ; Biology (General) ; QH301-705.5 ; Biotechnology ; TP248.13-248.65
    Subject code 612
    Language English
    Publishing date 2022-04-01T00:00:00Z
    Publisher AIMS Press
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article ; Online: The Diversity of Bacteriophages in Hot Springs.

    Marks, Timothy J / Rowland, Isabella R

    Methods in molecular biology (Clifton, N.J.)

    2023  Volume 2738, Page(s) 73–88

    Abstract: ... including increased G + C DNA percentages, reliance upon the pentose phosphate metabolic pathway to avoid ... hot springs, which can range in temperatures between 40 and 98 °C and pH levels between 1 and 9 ...

    Abstract Bacteriophages are ubiquitous in all environments that support microbial life. This includes hot springs, which can range in temperatures between 40 and 98 °C and pH levels between 1 and 9. Bacteriophages that survive in the higher temperatures of hot springs are known as thermophages. Thermophages have developed distinct adaptations allowing for thermostability in these extreme environments, including increased G + C DNA percentages, reliance upon the pentose phosphate metabolic pathway to avoid oxidative stress, and a codon preference for those with a GNA sequence leading to increased hydrophobic interactions and disulfide bonds. In this review, we discuss the diversity of characterized thermophages in hot spring environments that span five viral families: Myoviridae, Siphoviridae, Tectiviridae, Sphaerolipoviridae, and Inoviridae. Potential industrial and medicinal applications of thermophages will also be addressed.
    MeSH term(s) Humans ; Bacteriophages/genetics ; Hot Springs ; Myoviridae ; Siphoviridae ; Extreme Environments
    Language English
    Publishing date 2023-11-15
    Publishing country United States
    Document type Review ; Journal Article
    ISSN 1940-6029
    ISSN (online) 1940-6029
    DOI 10.1007/978-1-0716-3549-0_4
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  5. Article ; Online: Effect of Air Temperature and Velocity on Listeria monocytogenes Inactivation During Drying of Apple Slices.

    Randriamiarintsoa, Narindra / Ryser, Elliot T / Marks, Bradley P

    Journal of food protection

    2024  Volume 87, Issue 4, Page(s) 100253

    Abstract: ... 0.3 log CFU/g. Apple rings were dried in batches using dry air in a pilot-scale impingement oven ... at 60 or 80 °C air temperature and 0.7 or 2.1 m/s air velocity, and sampled every 30 min for bacterial ...

    Abstract A wide range of drying parameters and methods are used by industry to produce dried apples. To ensure end-product safety and regulatory compliance, it is essential to evaluate the effectiveness of such industrial practices on microbial inactivation. Therefore, the objective of this study was to evaluate the effects of drying air temperature and velocity on Listeria monocytogenes inactivation during drying of apple slices. Apples (cv. Gala) were cored, sliced as rings (∼6 mm thick), and surface-inoculated with broth-grown culture of an 8-strain cocktail of L. monocytogenes to achieve an inoculation level of 8.6 ± 0.3 log CFU/g. Apple rings were dried in batches using dry air in a pilot-scale impingement oven at 60 or 80 °C air temperature and 0.7 or 2.1 m/s air velocity, and sampled every 30 min for bacterial enumeration, water activity (a
    MeSH term(s) Malus/microbiology ; Temperature ; Listeria monocytogenes ; Colony Count, Microbial ; Fruit/microbiology ; Food Microbiology ; Food Handling/methods
    Language English
    Publishing date 2024-02-28
    Publishing country United States
    Document type Journal Article
    ZDB-ID 243284-5
    ISSN 1944-9097 ; 0362-028X
    ISSN (online) 1944-9097
    ISSN 0362-028X
    DOI 10.1016/j.jfp.2024.100253
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    In stock of ZB MED Bonn / Germany

    Z 2631: Show issues

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  6. Article ; Online: Red cells manufactured from lipaemic whole blood donations: Do they have higher haemolysis?

    Winter, Kelly M / Webb, Rachel G / Marks, Denese C

    Vox sanguinis

    2022  

    Abstract: Background and objectives: Lipaemia in blood donations is thought to influence haemolysis in stored red blood cell (RBC) components. Higher lipid concentrations are believed to increase red cell fragility, exacerbating haemolysis during collection and ... ...

    Abstract Background and objectives: Lipaemia in blood donations is thought to influence haemolysis in stored red blood cell (RBC) components. Higher lipid concentrations are believed to increase red cell fragility, exacerbating haemolysis during collection and subsequent red cell storage. This study aimed to investigate associations between lipoproteins in plasma and haemolysis of red cells stored in saline-adenine-glucose-mannitol (SAGM).
    Materials and methods: Fifty-four plasma and matched RBCs were obtained from lipaemic whole blood donations. Plasma was tested for coagulation factors, triglycerides and cholesterol. Haemolysis, glucose, lactate, extracellular potassium, lactate dehydrogenase and adenosine triphosphate (ATP) were measured in RBC on Days 7, 21 and 42 of storage. Additionally, 20 plasma and matched RBCs from non-lipaemic donations were tested as controls.
    Results: Lipaemic plasma had significantly higher triglyceride concentrations compared with non-lipaemic plasma. However, there was no significant difference in plasma cholesterol between the two groups. There were no significant differences in glucose, extracellular potassium or ATP concentrations in RBC from either group. There was no significant difference in haemolysis at expiry in lipaemic-derived and control RBC, with a weak correlation between haemolysis and either triglycerides or cholesterol.
    Conclusion: There was no significant difference in haemolysis in RBC manufactured from lipaemic and non-lipaemic whole blood donations when stored in SAGM; however, the proportion of RBC from lipaemic donations with higher haemolysis was greater than in the controls. There was a weak correlation between red cell haemolysis and plasma triglycerides. Therefore, RBCs derived from lipaemic donations are suitable for blood bank inventories.
    Language English
    Publishing date 2022-10-10
    Publishing country England
    Document type Journal Article
    ZDB-ID 80313-3
    ISSN 1423-0410 ; 0042-9007
    ISSN (online) 1423-0410
    ISSN 0042-9007
    DOI 10.1111/vox.13366
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 74: Show issues Location:
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  7. Article ; Online: Potential benefits of active case finding to reduce the burden of TB.

    Linh, N N / Miller, C / Marks, G B

    The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease

    2021  Volume 25, Issue 2, Page(s) 93–94

    MeSH term(s) Humans ; Mass Screening ; Tuberculosis/diagnosis ; Tuberculosis/epidemiology ; Tuberculosis/prevention & control
    Language English
    Publishing date 2021-03-03
    Publishing country France
    Document type Journal Article
    ZDB-ID 1385624-8
    ISSN 1815-7920 ; 1027-3719
    ISSN (online) 1815-7920
    ISSN 1027-3719
    DOI 10.5588/ijtld.20.0894
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4776: Show issues Location:
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    Zs.MO 261: Show issues

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  8. Article ; Online: Robotic right colectomy with robotic-sewn anastomosis: a pilot case series.

    Huscher, C G S / Lazzarin, Gianni / Marchegiani, F / Marks, J

    Journal of robotic surgery

    2022  Volume 17, Issue 2, Page(s) 427–434

    Abstract: The background of this study is to assess the feasibility, clinical utility and safety of intra-corporeal robotic-sewn anastomosis (ICrA) in completely robotic right hemicolectomy (CRH) for adenocarcinoma. A protocol for completely robotic right ... ...

    Abstract The background of this study is to assess the feasibility, clinical utility and safety of intra-corporeal robotic-sewn anastomosis (ICrA) in completely robotic right hemicolectomy (CRH) for adenocarcinoma. A protocol for completely robotic right hemicolectomy (CRH) and intra-corporeal robotic-sewn anastomosis (ICrA), was established at the authors' institution from January 2012 through December 2017. Univariate and multivariable models were constructed to explore the prognostic significance of clinical and surgical findings. Survival and recurrence analysis were performed using standard univariable and multivariable methods. The study population consisted of 123 patients. The median number of examined lymph nodes (ELN) was 25 (range 1-59), the median number of positive lymph nodes (PLN) was 1 (range 0-21). Mean operative time was 240 min (SD 43.56, range 180-360 min), and conversion to open rate was 0%. Anastomotic leaks rate was 1.6%. The median overall survival was 69 months. This pilot series, in which an intra-corporeal robotic-sewn anastomosis (ICrA) was performed during CRH, demonstrated the safety and feasibility of this approach. Compared to the current standard of care at a high-volume center, ICrA was associated with post-operative surgical outcomes similar to those reported in the literature. These results call for further validation in a prospective and controlled setting to be fully incorporated into clinical practice.
    MeSH term(s) Humans ; Robotic Surgical Procedures/methods ; Prospective Studies ; Robotics ; Colectomy/methods ; Anastomosis, Surgical/methods ; Laparoscopy/methods ; Colonic Neoplasms/surgery ; Retrospective Studies ; Treatment Outcome
    Language English
    Publishing date 2022-06-26
    Publishing country England
    Document type Journal Article
    ZDB-ID 2268283-1
    ISSN 1863-2491 ; 1863-2483
    ISSN (online) 1863-2491
    ISSN 1863-2483
    DOI 10.1007/s11701-022-01435-4
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  9. Article ; Online: Which trial do we need? Long-acting glycopeptides versus oral antibiotics for infective endocarditis in patients with substance use disorder.

    Wurcel, Alysse G / DeSimone, Daniel C / Marks, Laura / Baddour, Larry M / Sendi, Parham

    Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases

    2023  Volume 29, Issue 8, Page(s) 952–954

    MeSH term(s) Humans ; Anti-Bacterial Agents/therapeutic use ; Glycopeptides/therapeutic use ; Endocarditis, Bacterial/drug therapy ; Endocarditis/drug therapy ; Substance-Related Disorders/drug therapy
    Chemical Substances Anti-Bacterial Agents ; Glycopeptides
    Language English
    Publishing date 2023-04-10
    Publishing country England
    Document type Journal Article
    ZDB-ID 1328418-6
    ISSN 1469-0691 ; 1470-9465 ; 1198-743X
    ISSN (online) 1469-0691
    ISSN 1470-9465 ; 1198-743X
    DOI 10.1016/j.cmi.2023.04.005
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    Zs.MO 284: Show issues

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  10. Article ; Online: Dr Christopher Zishiri.

    Dlodlo, R A / Ncube, R T / Dhlakama, D / Nyathi, B B / Sandy, C / Marks, G

    The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease

    2022  Volume 26, Issue 11, Page(s) 1095–1096

    Language English
    Publishing date 2022-10-11
    Publishing country France
    Document type Journal Article
    ZDB-ID 1385624-8
    ISSN 1815-7920 ; 1027-3719
    ISSN (online) 1815-7920
    ISSN 1027-3719
    DOI 10.5588/ijtld.22.0401
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