Article ; Online: Polymonoclonal (Not Polyclonal) Antibodies Derived from Convalescent Human B Cell Hybridomas Might Be a Better Therapeutic Option than Single Target Monoclonal Antibodies.
ACS pharmacology & translational science
2020 Volume 3, Issue 4, Page(s) 786–787
Abstract: Both human B cell hybridoma technology and convalescent plasma therapy are promising immunological tools for therapeutic interventions. Here we propose using antibody producing B cells from convalescent SARS-CoV2 patients for developing human B cell ... ...
Abstract | Both human B cell hybridoma technology and convalescent plasma therapy are promising immunological tools for therapeutic interventions. Here we propose using antibody producing B cells from convalescent SARS-CoV2 patients for developing human B cell hybridomas, and a combination of monoclonal antibodies against multiple immunogenic targets of SARS-CoV-2 spike protein might deliver an antibody cocktail for long-lasting therapeutic targeting. |
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Keywords | covid19 |
Language | English |
Publishing date | 2020-07-24 |
Publishing country | United States |
Document type | Journal Article |
ISSN | 2575-9108 |
ISSN (online) | 2575-9108 |
DOI | 10.1021/acsptsci.0c00084 |
Database | MEDical Literature Analysis and Retrieval System OnLINE |
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