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  1. Article: The 2018 Ming K. Jeang award for excellence in

    Shi, Yun-Bo

    Cell & bioscience

    2019  Volume 9, Page(s) 42

    Abstract: ... of Southern University of Science and Technology, Shenzhen, China, respectively, won the 2017 Ming K. Jeang ...

    Abstract Two research papers, one from a group led by Dr. Haifan Lin of Yale University School of Medicine, New Haven, USA and another from two laboratories led by Drs. Yihong Ye of National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, USA, and Ting Zhang of Southern University of Science and Technology, Shenzhen, China, respectively, won the 2017 Ming K. Jeang Award for Excellence in
    Language English
    Publishing date 2019-05-20
    Publishing country England
    Document type Editorial
    ZDB-ID 2593367-X
    ISSN 2045-3701
    ISSN 2045-3701
    DOI 10.1186/s13578-019-0305-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: [Fracture images in temple murals for sacrificial activities in the Ming and Qing Dynasties in Shanxi].

    Shi, H L / Yi, B

    Zhonghua yi shi za zhi (Beijing, China : 1980)

    2022  Volume 52, Issue 3, Page(s) 173–176

    Abstract: ... Buddhist rituals for sacrificial activities in the Ming and Qing Dynasties. Some 'fracture images' ... realistic style, as vivid portrayals of surgical medicine in the Ming Dynasty. For instance, one ...

    Abstract A great number of 'fracture images' in murals remain in some temples in Shanxi province, describing Buddhist rituals for sacrificial activities in the Ming and Qing Dynasties. Some 'fracture images', such as 'splint fixation method' and 'suspension fixation method', were found in Puguang Temple, Yunlin Temple and Yong'an Temple. These murals with 'fracture images' demonstrated characteristics of secularisation and realistic style, as vivid portrayals of surgical medicine in the Ming Dynasty. For instance, one of the pictures in Puguang Temple clearly described the shape of orthopedic splints at that time. The depictions in 'fracture images' in temple murals were basically consistent with the records in ancient literature based on the investigation on fracture treatment in the history of traditional Chinese medicine. They provided visual materials for further study of orthopedic history.
    MeSH term(s) Buddhism ; China ; Medicine, Chinese Traditional ; Orthopedics
    Language Chinese
    Publishing date 2022-07-01
    Publishing country China
    Document type Journal Article
    ZDB-ID 1052411-3
    ISSN 0255-7053
    ISSN 0255-7053
    DOI 10.3760/cma.j.cn112155112155-20200710-00109
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

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  3. Article: The 2017 Ming K. Jeang award for excellence in

    Shi, Yun-Bo

    Cell & bioscience

    2018  Volume 8, Page(s) 44

    Abstract: ... respectively, won the 2017 Ming K Jeang Award for Excellence in ...

    Abstract Two research groups led by Dr. Shui Qing Ye of University of Missouri Kansas City School of Medicine, Kansas City, USA and Dr. Dihua Yu of University of Texas MD Anderson Cancer Center, Houston, USA, respectively, won the 2017 Ming K Jeang Award for Excellence in
    Language English
    Publishing date 2018-07-24
    Publishing country England
    Document type Editorial
    ZDB-ID 2593367-X
    ISSN 2045-3701
    ISSN 2045-3701
    DOI 10.1186/s13578-018-0241-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: The 2016 Ming K Jeang Award for Excellence in

    Shi, Yun-Bo

    Cell & bioscience

    2017  Volume 7, Page(s) 40

    Abstract: ... of Rutgers University, USA, respectively, won the 2016 Ming K Jeang Award for Excellence in ...

    Abstract Two research groups led by Dr. Jim Hu of University of Toronto, Canada and Dr. Renping Zhou of Rutgers University, USA, respectively, won the 2016 Ming K Jeang Award for Excellence in
    Language English
    Publishing date 2017-08-10
    Publishing country England
    Document type Editorial
    ZDB-ID 2593367-X
    ISSN 2045-3701
    ISSN 2045-3701
    DOI 10.1186/s13578-017-0169-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Ming-Mu-Di-Huang-Pill Activates SQSTM1 via AMPK-Mediated Autophagic KEAP1 Degradation and Protects RPE Cells from Oxidative Damage.

    Chen, Xi / Zhu, Yujie / Shi, Xiaoqing / Zuo, Jing / Hu, Tianming / Wu, Hao / Xia, Ying / Shi, Wei / Wei, Wei

    Oxidative medicine and cellular longevity

    2022  Volume 2022, Page(s) 5851315

    Abstract: ... been identified as an important strategy to protect RPE cells from oxidative damage. Ming-Mu-Di-Huang ...

    Abstract Oxidative stress and diminished autophagy in the retinal pigment epithelium (RPE) play crucial roles in the pathogenesis of age-related macular degeneration (AMD). Enhancing autophagy has recently been identified as an important strategy to protect RPE cells from oxidative damage. Ming-Mu-Di-Huang-Pill (MMDH pill) is a traditional herbal medicine used to treat AMD, and its molecular mechanism is not well understood. The aim of the present study was to investigate whether the MMDH pill relieved acute oxidative damage by activating autophagy in an in vitro and in vivo model of sodium iodate (NaIO
    MeSH term(s) AMP-Activated Protein Kinases/metabolism ; Autophagy/physiology ; Kelch-Like ECH-Associated Protein 1/metabolism ; NF-E2-Related Factor 2/metabolism ; Oxidative Stress/physiology ; Sequestosome-1 Protein/metabolism
    Chemical Substances Kelch-Like ECH-Associated Protein 1 ; NF-E2-Related Factor 2 ; Sequestosome-1 Protein ; AMP-Activated Protein Kinases (EC 2.7.11.31)
    Language English
    Publishing date 2022-03-25
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2455981-7
    ISSN 1942-0994 ; 1942-0994
    ISSN (online) 1942-0994
    ISSN 1942-0994
    DOI 10.1155/2022/5851315
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: [Comparative study on the academic thought of bloodletting for expelling pathogens between Jin-Yuan Dynasties and Ming-Qing Dynasties].

    Chen, Hao / She, Yan-Fen / Gao, Ya-Yu / Song, Xiao-Dan / Fan, Xi-Sheng / Shi, Xu-Liang / Dong, Shang-Pu / Lv, Jing

    Zhongguo zhen jiu = Chinese acupuncture & moxibustion

    2021  Volume 41, Issue 7, Page(s) 813–817

    Abstract: ... of the medical representative scholars in Jin-Yuan Dynasties and Ming-Qing Dynasties respectively to construct ... the databases of bloodletting for expelling pathogens of Jin-Yuan Dynasties and Ming-Qing Dynasties. Using ... that the three-edge needle is the most commonly used device for bloodletting in Jin-Yuan Dynasties and Ming-Qing ...

    Abstract The relevant provisions of bloodletting for expelling pathogens are collected from the works of the medical representative scholars in Jin-Yuan Dynasties and Ming-Qing Dynasties respectively to construct the databases of bloodletting for expelling pathogens of Jin-Yuan Dynasties and Ming-Qing Dynasties. Using frequency analysis, the bloodletting device, bloodletting location, bloodletting volume, the related pathogens and indications are compared between these two times so that the evidences could be provided for the inheritance and development of the academic thought of bloodletting for expelling pathogens. It is found that the three-edge needle is the most commonly used device for bloodletting in Jin-Yuan Dynasties and Ming-Qing Dynasties and
    MeSH term(s) Acupuncture Points ; Bloodletting ; China ; Medicine, Chinese Traditional ; Meridians ; Needles
    Language Chinese
    Publishing date 2021-07-14
    Publishing country China
    Document type Journal Article
    ISSN 0255-2930
    ISSN 0255-2930
    DOI 10.13703/j.0255-2930.20200609-k0002
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Inter-library loan at ZB MED

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  7. Article ; Online: Network pharmacology and experimental evidence reveal the protective mechanism of Yi-Qi Cong-Ming decoction on age-related hearing loss.

    Yang, Yi-Fang / Yan, Xi-Rui / Wu, Rui-Xin / Li, Ning / Chu, Min / Dong, Yang / Fu, Shu-Ping / Shi, Jian-Rong / Liu, Qing

    Pharmaceutical biology

    2022  Volume 60, Issue 1, Page(s) 1478–1490

    Abstract: Context: Yi-Qi Cong-Ming (YQCM) decoction has been widely used to prevent age-related hearing loss ...

    Abstract Context: Yi-Qi Cong-Ming (YQCM) decoction has been widely used to prevent age-related hearing loss (ARHL), the most prevalent neurodegenerative disease in the elderly.
    Objective: To explore the mechanism of YQCM decoction in the treatment of ARHL.
    Materials and methods: The chemical constituents of YQCM were screened from the Traditional Chinese Medicine Systems Pharmacology Database. Potential targets of YQCM against ARHL were predicted by DrugBank, GeneCards, and OMIM database. Protein-protein network and enrichment analysis were used for exploring possible molecular mechanisms. Molecular docking and an
    Results: The main compounds have good affinities with hub targets, especially AKT1, PTGS2, and CASP3. GO and KEGG analysis showed that the main biological process and key targets were related to negative regulation of the apoptotic process. H
    Conclusions: Our study suggested that YQCM prevents ARHL by modulating the apoptosis process in auditory hair cells. Moreover, this study proved that bioinformatics analysis combined with molecular docking and cell model is a promising method to explore other possible pharmacological interventions of ARHL.
    MeSH term(s) Aged ; Caspase 3 ; Drugs, Chinese Herbal/therapeutic use ; Hearing Loss/drug therapy ; Humans ; Hydrogen Peroxide/toxicity ; Medicine, Chinese Traditional/methods ; Molecular Docking Simulation ; Network Pharmacology ; Neurodegenerative Diseases/drug therapy
    Chemical Substances Drugs, Chinese Herbal ; Hydrogen Peroxide (BBX060AN9V) ; Caspase 3 (EC 3.4.22.-)
    Language English
    Publishing date 2022-08-08
    Publishing country England
    Document type Journal Article
    ZDB-ID 1440131-9
    ISSN 1744-5116 ; 1388-0209
    ISSN (online) 1744-5116
    ISSN 1388-0209
    DOI 10.1080/13880209.2022.2101671
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 1300: Show issues Location:
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  8. Article ; Online: The 2018 Ming K. Jeang award for excellence in Cell & Bioscience

    Yun-Bo Shi

    Cell & Bioscience, Vol 9, Iss 1, Pp 1-

    2019  Volume 1

    Abstract: ... of Southern University of Science and Technology, Shenzhen, China, respectively, won the 2017 Ming K. Jeang ...

    Abstract Abstract Two research papers, one from a group led by Dr. Haifan Lin of Yale University School of Medicine, New Haven, USA and another from two laboratories led by Drs. Yihong Ye of National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, USA, and Ting Zhang of Southern University of Science and Technology, Shenzhen, China, respectively, won the 2017 Ming K. Jeang Award for Excellence in Cell & Bioscience.
    Keywords Biotechnology ; TP248.13-248.65 ; Biology (General) ; QH301-705.5 ; Biochemistry ; QD415-436
    Language English
    Publishing date 2019-05-01T00:00:00Z
    Publisher BMC
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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  9. Article: The 2015 Ming K Jeang Award for Excellence in Cell & Bioscience.

    Shi, Yun-Bo

    Cell & bioscience

    2016  Volume 6, Page(s) 27

    Abstract: ... National Institutes of Health, MD, USA, respectively, won the 2015 Ming K Jeang Award for excellence ...

    Abstract Two research groups led by Dr. Bin Gao of National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, MD, USA and Dr. Keji Zhao of National Heart, Lung, and Blood Institute, National Institutes of Health, MD, USA, respectively, won the 2015 Ming K Jeang Award for excellence in Cell & Bioscience.
    Language English
    Publishing date 2016-04-19
    Publishing country England
    Document type Journal Article
    ZDB-ID 2593367-X
    ISSN 2045-3701
    ISSN 2045-3701
    DOI 10.1186/s13578-016-0093-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Network pharmacology and experimental evidence reveal the protective mechanism of Yi-Qi Cong-Ming decoction on age-related hearing loss

    Yang, Yi-Fang / Yan, Xi-Rui / Wu, Rui-Xin / Li, Ning / Zhu, Min / Dong, Yang / Fu, Shu-Ping / Shi, Jian-Rong / Liu, Qing

    Pharmaceutical Biology. 2022 Dec. 31, v. 60, no. 1 p.1478-1490

    2022  

    Abstract: Yi-Qi Cong-Ming (YQCM) decoction has been widely used to prevent age-related hearing loss (ARHL ...

    Abstract Yi-Qi Cong-Ming (YQCM) decoction has been widely used to prevent age-related hearing loss (ARHL), the most prevalent neurodegenerative disease in the elderly. To explore the mechanism of YQCM decoction in the treatment of ARHL. The chemical constituents of YQCM were screened from the Traditional Chinese Medicine Systems Pharmacology Database. Potential targets of YQCM against ARHL were predicted by DrugBank, GeneCards, and OMIM database. Protein-protein network and enrichment analysis were used for exploring possible molecular mechanisms. Molecular docking and an in vitro model of ARHL by exposing auditory cells with 100 μM H₂O₂ for 3 h were applied. Cell viability and mitochondrial membrane potential (ΔΨM) were detected by CCK-8 and high-content analysis. γH2AX and cleaved caspase-3 were detected by Western blot. The main compounds have good affinities with hub targets, especially AKT1, PTGS2, and CASP3. GO and KEGG analysis showed that the main biological process and key targets were related to negative regulation of the apoptotic process. H₂O₂ treatment could reduce the cell viability by 68% and impaired ΔΨM, while 90 μg/mL YQCM pre-treatment could restore the cell viability by 97.45% and increase ΔΨM (2-fold higher). YQCM pre-treatment also reduced γH2AX and cleaved caspase-3 protein levels. Our study suggested that YQCM prevents ARHL by modulating the apoptosis process in auditory hair cells. Moreover, this study proved that bioinformatics analysis combined with molecular docking and cell model is a promising method to explore other possible pharmacological interventions of ARHL.
    Keywords Oriental traditional medicine ; Western blotting ; apoptosis ; bioinformatics ; caspase-3 ; cell viability ; databases ; elderly ; membrane potential ; mitochondrial membrane ; models ; neurodegenerative diseases ; pharmacology ; Molecular docking ; molecular dynamics simulation ; HEI-OC1 ; mitochondrial membrane potential ; AKT1
    Language English
    Dates of publication 2022-1231
    Size p. 1478-1490.
    Publishing place Taylor & Francis
    Document type Article ; Online
    ZDB-ID 1440131-9
    ISSN 1744-5116 ; 1388-0209
    ISSN (online) 1744-5116
    ISSN 1388-0209
    DOI 10.1080/13880209.2022.2101671
    Database NAL-Catalogue (AGRICOLA)

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