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  1. Article: Sheikh Abdullah and the politics of Kashmir

    Lockwood, David E / Abdullah, Sheikh

    Asian survey : a bimonthly review of contemporary Asian affairs Vol. 9, No. 5 , p. 382-396

    1969  Volume 9, Issue 5, Page(s) 382–396

    Author's details David E. Lockwood
    Keywords Nationale Selbstbestimmung ; Indien ; Kaschmir
    Publisher Univ. of California Press
    Publishing place Berkeley, Calif.
    Document type Article
    ZDB-ID 280167x
    Database ECONomics Information System

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  2. Article: Mitochondrial DNA sequencing of Kehilan and Hamdani horses from Saudi Arabia.

    Sheikh, Abdullah

    Saudi journal of biological sciences

    2023  Volume 30, Issue 9, Page(s) 103741

    Abstract: The Arabian horse breed is well known for its purity and played a key role in the genetic improvement of other horses worldwide. The mitochondrial genome plays a vital role in maternal inheritance and it's helpful to evaluate its genetic diversity and ... ...

    Abstract The Arabian horse breed is well known for its purity and played a key role in the genetic improvement of other horses worldwide. The mitochondrial genome plays a vital role in maternal inheritance and it's helpful to evaluate its genetic diversity and conservation. It has higher mutation rates than nuclear DNA in vertebrates and therefore reveals phylogenetic relationships and haplotypes. In this study, the mitochondrial genome mutations in two Saudi horse strains, Kehilan and Hamdani demonstrated various changes in the gene and amino acid levels and included two other Saudi horses (Hadban and Seglawi) from the previous study for phylogenetic comparison. The whole mitochondrial genome sequencing resulted in intra and inter mtDNA variations between the studied horses. Interestingly, the Hamdani horse has nucleotide substitutions similar to those of the Hadban horse, which is reflected in the phylogenetic tree as a significantly close relationship. This type of study provides a better understanding of mitogenome structure and conservation of livestock species genetic data.
    Language English
    Publishing date 2023-07-20
    Publishing country Saudi Arabia
    Document type Journal Article
    ZDB-ID 2515206-3
    ISSN 2213-7106 ; 1319-562X
    ISSN (online) 2213-7106
    ISSN 1319-562X
    DOI 10.1016/j.sjbs.2023.103741
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Potential role of tubulin glutamylation in neurodegenerative diseases.

    Sheikh, Abdullah Md / Tabassum, Shatera

    Neural regeneration research

    2023  Volume 19, Issue 6, Page(s) 1191–1192

    Language English
    Publishing date 2023-09-22
    Publishing country India
    Document type Journal Article
    ZDB-ID 2388460-5
    ISSN 1876-7958 ; 1673-5374
    ISSN (online) 1876-7958
    ISSN 1673-5374
    DOI 10.4103/1673-5374.385859
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Molecular detection of ruminal micro-flora and micro-fauna in Saudi Arabian camels: Effects of season and region.

    Abdullah, Hashim M / Mohammed, Osama B / Sheikh, Abdullah / Almathen, Faisal / Khalid, Ahmed M / Bakhiet, Amel O / Abdelrahman, Mutassim M

    Saudi journal of biological sciences

    2024  Volume 31, Issue 5, Page(s) 103982

    Abstract: This study investigated and explored the availability of micro-flora and micro-fauna in the ruminal contents of Arabian camel ( ...

    Abstract This study investigated and explored the availability of micro-flora and micro-fauna in the ruminal contents of Arabian camel (
    Language English
    Publishing date 2024-03-23
    Publishing country Saudi Arabia
    Document type Journal Article
    ZDB-ID 2515206-3
    ISSN 2213-7106 ; 1319-562X
    ISSN (online) 2213-7106
    ISSN 1319-562X
    DOI 10.1016/j.sjbs.2024.103982
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Mangifera indica L

    Alshwyeh, Hussah Abdullah / Al-Sheikh, Warqaa Muhammed Shariff / Rasedee, Abdullah / Alnasser, Sulaiman Mohammed / Al-Qubaisi, Mothanna Sadiq / Ibrahim, Wisam Nabeel

    Molecular & cellular oncology

    2024  Volume 11, Issue 1, Page(s) 2299046

    Abstract: In this study, we investigated the effects of an ethanolic extract ... ...

    Abstract In this study, we investigated the effects of an ethanolic extract of
    Language English
    Publishing date 2024-01-04
    Publishing country United States
    Document type Journal Article
    ISSN 2372-3556
    ISSN 2372-3556
    DOI 10.1080/23723556.2023.2299046
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Bacillus subtilis

    Khalifa, Ashraf / Ibrahim, Hairul-Islam Mohamed / Sheikh, Abdullah

    Microorganisms

    2023  Volume 11, Issue 7

    Abstract: With the practice of a successful livestock industry using antibiotics, which has continued for more than five decades, researchers have long been interested in finding alternatives to antibiotics for poultry production. Probiotics can potentially reduce ...

    Abstract With the practice of a successful livestock industry using antibiotics, which has continued for more than five decades, researchers have long been interested in finding alternatives to antibiotics for poultry production. Probiotics can potentially reduce enteric diseases in livestock and enhance their productivity. The aim of this study was to isolate putative probiotics from camel milk and test them against
    Language English
    Publishing date 2023-06-30
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2720891-6
    ISSN 2076-2607
    ISSN 2076-2607
    DOI 10.3390/microorganisms11071719
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: A small animal model of NASH with progressive steatohepatitis -induced by fast food diet and alcohol in C57BL/6J mouse with high human pathophysiological proximity.

    Sharma, Raghu Rai / Rashid, Haroon / Tasduq Abdullah, Sheikh

    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association

    2023  Volume 178, Page(s) 113851

    Abstract: Non-alcoholic steatohepatitis (NASH) and alcoholic steatohepatitis (ASH) both can progress to end-stage liver disease (ESLD). No relevant animal models are available for studying the toxic consequences of concurrent fast food diet and alcohol usage in ... ...

    Abstract Non-alcoholic steatohepatitis (NASH) and alcoholic steatohepatitis (ASH) both can progress to end-stage liver disease (ESLD). No relevant animal models are available for studying the toxic consequences of concurrent fast food diet and alcohol usage in fibrosing NASH. As a result, dependable and short-term in-vivo models capable of recapitulating human disease pathophysiology are required for deciphering mechanistic insights and preclinical drug discovery programs. The current study aims to develop a mouse model for progressive steatohepatitis employing a fast food (FF) diet with intermittent oral alcohol (EtOH) administration. For eight (8) weeks, C57BL/6J mice were fed standard chow (SC) diet ± EtOH or FF ± EtOH. EtOH uses enhanced the histological characteristics of FF -induced steatohepatitis and fibrosis. A dysregulated molecular signaling cascade related to oxidative stress, steatosis, fibrosis, DNA damage, and apoptosis was evident at protein and gene expression levels in the FF + EtOH. The results from the in-vivo model were replicated in mouse hepatocyte cultures (AML-12) subjected to palmitic acid (PA) ± EtOH exposures. The results of the present study indicate that the clinical hallmarks of human progressive steatohepatitis and fibrosis were achieved in our mice model, showing its suitability for preclinical research.
    MeSH term(s) Humans ; Mice ; Animals ; Non-alcoholic Fatty Liver Disease/metabolism ; Liver/metabolism ; Fast Foods ; Mice, Inbred C57BL ; Diet, High-Fat ; Ethanol/toxicity ; Ethanol/metabolism ; Disease Models, Animal ; Liver Cirrhosis/pathology
    Chemical Substances Ethanol (3K9958V90M)
    Language English
    Publishing date 2023-06-02
    Publishing country England
    Document type Journal Article
    ZDB-ID 782617-5
    ISSN 1873-6351 ; 0278-6915
    ISSN (online) 1873-6351
    ISSN 0278-6915
    DOI 10.1016/j.fct.2023.113851
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
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  8. Article ; Online: The Role of the Vascular System in Degenerative Diseases: Mechanisms and Implications.

    Sheikh, Abdullah Md / Yano, Shozo / Tabassum, Shatera / Nagai, Atsushi

    International journal of molecular sciences

    2024  Volume 25, Issue 4

    Abstract: Degenerative diseases, encompassing a wide range of conditions affecting various organ systems, pose significant challenges to global healthcare systems. This comprehensive review explores the intricate interplay between the vascular system and ... ...

    Abstract Degenerative diseases, encompassing a wide range of conditions affecting various organ systems, pose significant challenges to global healthcare systems. This comprehensive review explores the intricate interplay between the vascular system and degenerative diseases, shedding light on the underlying mechanisms and profound implications for disease progression and management. The pivotal role of the vascular system in maintaining tissue homeostasis is highlighted, as it serves as the conduit for oxygen, nutrients, and immune cells to vital organs and tissues. Due to the vital role of the vascular system in maintaining homeostasis, its dysfunction, characterized by impaired blood flow, endothelial dysfunction, and vascular inflammation, emerges as a common denominator of degenerative diseases across multiple systems. In the nervous system, we explored the influence of vascular factors on neurodegenerative diseases such as Alzheimer's and Parkinson's, emphasizing the critical role of cerebral blood flow regulation and the blood-brain barrier. Within the kidney system, the intricate relationship between vascular health and chronic kidney disease is scrutinized, unraveling the mechanisms by which hypertension and other vascular factors contribute to renal dysfunction. Throughout this review, we emphasize the clinical significance of understanding vascular involvement in degenerative diseases and potential therapeutic interventions targeting vascular health, highlighting emerging treatments and prevention strategies. In conclusion, a profound appreciation of the role of the vascular system in degenerative diseases is essential for advancing our understanding of degenerative disease pathogenesis and developing innovative approaches for prevention and treatment. This review provides a comprehensive foundation for researchers, clinicians, and policymakers seeking to address the intricate relationship between vascular health and degenerative diseases in pursuit of improved patient outcomes and enhanced public health.
    MeSH term(s) Humans ; Blood-Brain Barrier/pathology ; Neurodegenerative Diseases/pathology ; Cerebrovascular Circulation ; Biological Transport ; Homeostasis
    Language English
    Publishing date 2024-02-11
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms25042169
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Epipericardial Fat Necrosis and Covid-19.

    Haseeb, Mohsin / Shafiq, Abdullah / Sheikh, Muhammad A / Khan, Muhammad F

    European journal of case reports in internal medicine

    2024  Volume 11, Issue 3, Page(s) 4346

    Abstract: Background: Epipericardial fat necrosis (EFN) is a rare and self-limiting cause of acute chest pain. We describe a case of EFN in a patient with a recent coronavirus disease (COVID-19).: Case presentation: A 55-year-old male presented with a sudden ... ...

    Abstract Background: Epipericardial fat necrosis (EFN) is a rare and self-limiting cause of acute chest pain. We describe a case of EFN in a patient with a recent coronavirus disease (COVID-19).
    Case presentation: A 55-year-old male presented with a sudden onset of left-sided pleuritic chest pain for the past two days. The patient was diaphoretic, tachypneic, and tachycardic. Acute coronary syndrome was ruled out. A computed tomography (CT) pulmonary angiogram revealed an ovoid encapsulated fatty mass surrounded by dense appearing tissue. Patient symptoms improved remarkably with a short course of non-steroidal anti-inflammatory drugs (NSAIDs).
    Discussion: EFN typically presents with a sudden onset of excruciating chest pain. Misdiagnosis, under-diagnosis, and mismanagement are unavoidable. EFN is incidentally diagnosed on CT scan. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infects visceral adipose tissue and appears to increase the risk of EFN by promoting inflammatory cytokine production and death of adipocytes.
    Conclusion: EFN is a rare cause of acute chest pain. SARS-CoV-2 is likely to induce EFN. This rare clinical entity should be considered in the differential of acute chest pain especially in patients with active or recent COVID-19.
    Learning points: Epipericardial fat necrosis (EFN) is a rare cause of acute pleuritic chest pain that is often misdiagnosed and mismanaged.SARS-CoV-2 can possibly increase the risk of EFN and this entity should be considered in the differential of chest pain, especially in patients with active or recent coronavirus disease (COVID-19).Clinician awareness of EFN and its potential association with COVID-19, can reduce unnecessary testing and emotional distress.
    Language English
    Publishing date 2024-02-29
    Publishing country Italy
    Document type Journal Article
    ISSN 2284-2594
    ISSN (online) 2284-2594
    DOI 10.12890/2024_004346
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Ozone Layer Depletion and Emerging Public Health Concerns - An Update on Epidemiological Perspective of the Ambivalent Effects of Ultraviolet Radiation Exposure.

    Umar, Sheikh Ahmad / Tasduq, Sheikh Abdullah

    Frontiers in oncology

    2022  Volume 12, Page(s) 866733

    Abstract: Solar ultraviolet (UV) radiation exposure is the primary etiological agent responsible for developing cutaneous malignancies. Avoiding excessive radiation exposure, especially by high-risk groups, is recommended to prevent UV-induced photo-pathologies. ... ...

    Abstract Solar ultraviolet (UV) radiation exposure is the primary etiological agent responsible for developing cutaneous malignancies. Avoiding excessive radiation exposure, especially by high-risk groups, is recommended to prevent UV-induced photo-pathologies. However, optimal sun exposure is essential for the healthy synthesis of about 90% of vitamin D levels in the body. Insufficient exposure to UV-B is linked to vitamin D deficiency in humans. Therefore, optimal sun exposure is necessary for maintaining a normal state of homeostasis in the skin. Humans worldwide face a major existential threat because of climate change which has already shown its effects in several ways. Over the last 4 to 5 decades, increased incidences in skin cancer cases have led international health organizations to develop strong sun protection measures. However, at the same time, a growing concern about vitamin D deficiency is creating a kind of exposure dilemma. Current knowledge of UV exposure to skin outweighs the adverse effects than the beneficial roles it offers to the body, necessitating a correct public health recommendation on optimal sun exposure. Following an appropriate recommendation on optimal sun exposure will lead to positive outcomes in protecting humans against the adverse effects of strict recommendations on sun protection measures. In this short review, we spotlight the ambivalent health effects of UV exposure and how ozone layer depletion has influenced these effects of UVR. Further, our aim remains to explore how to lead towards a balanced recommendation on sun protection measures to prevent the spurt of diseases due to inadequate exposure to UV-B.
    Language English
    Publishing date 2022-03-10
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2649216-7
    ISSN 2234-943X
    ISSN 2234-943X
    DOI 10.3389/fonc.2022.866733
    Database MEDical Literature Analysis and Retrieval System OnLINE

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